Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

scientific article published on 16 April 2006

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1050800201
P356DOI10.1038/NATURE04721
P698PubMed publication ID16625206
P5875ResearchGate publication ID7155674

P50authorJaap GoudsmitQ2346715
Peter AbbinkQ47695590
Dan H. BarouchQ60489346
Anjali NandaQ63866123
Keith G MansfieldQ88124406
Michelle A LiftonQ95337710
Menzo HavengaQ104689196
Angelique LemckertQ104689197
Darci A GorgoneQ109916222
Angela A L CarvilleQ114439890
Lennart HoltermanQ114439894
Bonnie A EwaldQ114439895
P2093author name stringBing Chen
Jinyan Liu
Athmanundh Dilraj
Anna R Thorner
Diana M Lynch
Diane M Roberts
Patricia E Swanson
P2860cites workStructural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methodsQ24683349
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresQ26778412
The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 A resolutionQ30194037
Improved adenovirus vectors for infection of cardiovascular tissuesQ30657410
Immune response to recombinant capsid proteins of adenovirus in humans: antifiber and anti-penton base antibodies have a synergistic effect on neutralizing activity.Q33782487
Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype.Q33786378
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primatesQ34220503
Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag GeneQ34996554
Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunityQ35155049
Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectorsQ35640271
Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy VectorsQ37059464
Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vectorQ39146112
Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeysQ39612726
Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residuesQ39873800
Identification of adenovirus (ad) penton base neutralizing epitopes by use of sera from patients who had received conditionally replicative ad (addl1520) for treatment of liver tumorsQ40008652
Neutralization of adenoviruses: kinetics, stoichiometry, and mechanismsQ40128651
Hexon gene switch strategy for the generation of chimeric recombinant adenovirusQ43867091
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunityQ45734062
Development and homeostasis of T cell memory in rhesus macaqueQ45882091
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon proteinQ46499919
Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunityQ47644096
P433issue7090
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
P304page(s)239-243
P577publication date2006-04-16
P1433published inNatureQ180445
P1476titleHexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity
P478volume441

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