Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice

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Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1017544789
P356DOI10.1186/2049-3002-2-6
P3181OpenCitations bibliographic resource ID3171205
P932PMC publication ID4392529
P698PubMed publication ID24685128
P5875ResearchGate publication ID261255036

P2093author name stringStephen D Hursting
Laura M Lashinger
Audrey J Rasmussen
Kristyn A Liu
P2860cites workmTOR: from growth signal integration to cancer, diabetes and ageingQ24633662
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L-isoleucine and L-leucine: tumor promoters of bladder cancer in rats.Q53538192
Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles.Q54620948
Tumour and host tissue responses to branched-chain amino acid supplementation of patients with cancerQ72674390
The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in manQ79848490
Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormonesQ81536693
Leucine activates pancreatic translational machinery in rats and mice through mTOR independently of CCK and insulinQ83986611
Calorie restriction from a young age preserves the functions of pancreatic β cells in aging ratsQ84596440
Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. AdultsQ28131763
Leucine signaling in the pathogenesis of type 2 diabetes and obesityQ29543116
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Genetics: influence of TOR kinase on lifespan in C. elegansQ29616619
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Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapyQ34030634
Pancreatic cancer: state-of-the-art careQ34032937
High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFRQ34075493
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Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese miceQ34974569
Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia.Q35091299
mTOR-mediated regulation of translation factors by amino acidsQ35610885
Links between apoptosis, proliferation and the cell cycleQ35834632
Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolismQ36298705
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Calories and carcinogenesis: lessons learned from 30 years of calorie restriction researchQ37647283
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical foodQ37661185
Leucine nutrition in animals and humans: mTOR signaling and beyondQ37902970
Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes.Q37949691
Understanding the mechanisms and treatment options in cancer cachexiaQ38064733
Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice.Q39556506
High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cellsQ39642080
Free Amino Acids in Plasma during Experimental Infection of Mice with the MHV-3 Strain of Mouse Hepatitis VirusQ40100023
Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancerQ41970207
Cachexia in pancreatic cancer: new treatment options and measures of successQ42412515
Long-term treatment with L-isoleucine or L-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesisQ42511181
The possible role of leucine in modulating glucose homeostasis under distinct catabolic conditions.Q44452226
Abnormal glucose metabolism and pancreatic cancer mortalityQ44511450
Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscleQ44886230
Proteasome activity is altered in skeletal muscle tissue of tumour-bearing rats a leucine-rich diet.Q45197460
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
pancreatic cancerQ212961
P304page(s)6
P577publication date2014-01-01
P1433published inCancer & MetabolismQ27724831
P1476titleLeucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice
P478volume2

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cites work (P2860)
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