The detection, treatment, and biology of epithelial ovarian cancer

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The detection, treatment, and biology of epithelial ovarian cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1022538531
P356DOI10.1186/1757-2215-3-8
P932PMC publication ID2856581
P698PubMed publication ID20350313
P5875ResearchGate publication ID42638204

P2093author name stringJoseph P Connor
Manish S Patankar
Nick Claussen
Arvinder K Kapur
Jennifer Aa Gubbels
P2860cites workTL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulatorQ24292670
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesionQ24301956
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Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumorsQ24673454
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Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cellsQ28204913
Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)Q80580929
Tumor-derived soluble MICs impair CD3(+)CD56(+) NKT-like cell cytotoxicity in cancer patientsQ81728290
Humoral immune response to mesothelin in mesothelioma and ovarian cancer patientsQ81753024
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The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructureQ47178130
Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosisQ47347848
Interleukin-6 fused to an anti-idiotype antibody in a vaccine increases the specific humoral immune response against CA125+ (MUC-16) ovarian cancer.Q47826317
Intraperitoneal cisplatin plus intravenous cyclophosphamide versus intravenous cisplatin plus intravenous cyclophosphamide for stage III ovarian cancer.Q50512108
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Ascites from epithelial ovarian cancer contain high levels of functional decoy receptor 3 (DcR3) and is associated with platinum resistance.Q53458585
Isolation and characterization of human natural killer cell subsets.Q53481399
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.Q55042194
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activationQ59055770
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Elevation of serum CA125 in carcinomas of the fallopian tube, endometrium, and endocervixQ63446426
Monitoring human ovarian carcinoma with a combination of CA 125, CA 19-9, and carcinoembryonic antigenQ63446427
Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancerQ68090336
Elevated serum concentrations of CA-125 in patients with advanced endometriosisQ68723345
CA-125 in patients with endometriosisQ68963127
Extraovarian peritoneal serous papillary carcinoma. A clinicopathologic study of 31 casesQ69626773
Lymphocyte cytotoxicity in the peritoneal cavity and blood of patients with ovarian cancerQ70656081
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Monoclonal antibody immunoradiometric assay for an antigenic determinant (CA 125) associated with human epithelial ovarian carcinomasQ72722122
CA125 antigen levels in obstetric and gynecologic patientsQ72748884
Clinical course of ovarian cancer patients under repeated stimulation of HAMA using MAb OC125 and B43.13Q72754437
CA-125 in peritoneal fluid from patients with nonmalignant gynecologic disordersQ72819142
Serum and tissue measurements of CA72-4 in ovarian cancer patientsQ72947691
Induction of CA125-specific B and T cell responses in patients injected with MAb-B43.13--evidence for antibody-mediated antigen-processing and presentation of CA125 in vivoQ74260446
Prognostic factors in ovarian cancerQ74673849
Focus on epithelial ovarian cancerQ75353680
Distribution pattern and risk factors of pelvic and para-aortic lymph node metastasis in epithelial ovarian carcinomaQ77371908
Soluble epidermal growth factor receptor (sEGFR/sErbB1) as a potential risk, screening, and diagnostic serum biomarker of epithelial ovarian cancerQ78969303
The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A phase I trial of the AGO-OVARQ79149161
Use of CA125 fluctuation during the menstrual cycle as a tool in the clinical diagnosis of endometriosis; a preliminary reportQ80418026
Ovarian surface epithelium: biology, endocrinology, and pathologyQ28211321
Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2Q28212276
Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cellsQ28250971
SMRP and HE4 as biomarkers for ovarian carcinoma when used alone and in combination with CA125 and/or each otherQ28283527
Detection and quantitation of serum mesothelin, a tumor marker for patients with mesothelioma and ovarian cancerQ28293019
The cell of origin of ovarian epithelial tumoursQ28302089
Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epitheliumQ29030494
The distribution of secondary growths in cancer of the breast. 1889Q29614314
Tumor metastasis: mechanistic insights and clinical challengesQ29617676
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancerQ29620068
Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.Q30670385
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).Q30781823
A candidate precursor to serous carcinoma that originates in the distal fallopian tube.Q33264156
Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: an intergroup study of the GQ33335882
The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?Q33537711
Assessing lead time of selected ovarian cancer biomarkers: a nested case-control studyQ33574039
MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cellsQ33638962
Review: gonadotropins and development of ovarian cancerQ33764649
Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapyQ33828838
Mesothelin is not required for normal mouse development or reproductionQ33895649
Ovarian cancer: epidemiology, biology, and prognostic factorsQ33959805
Incessant ovulation--a factor in ovarian neoplasia?Q34051579
The CA 125 gene: an extracellular superstructure dominated by repeat sequencesQ34109036
Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin.Q34111770
Ovarian cancer antigen CA125 is encoded by the MUC16 mucin geneQ34121019
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.Q34211073
A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancerQ34254918
Potential markers that complement expression of CA125 in epithelial ovarian cancerQ34439240
EGF/ErbB receptor family in ovarian cancerQ34483792
Critical role of lysophospholipids in the pathophysiology, diagnosis, and management of ovarian cancer.Q34483798
Prevention and early detection of ovarian cancer: mission impossible?Q34575612
A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutationsQ34761925
Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutationsQ34811314
Status of Tumor Markers in Ovarian Cancer ScreeningQ35125949
Ovarian cancer: strategies for overcoming resistance to chemotherapyQ35166813
Modulation of TcR/CD3-zeta chain expression by a circulating factor derived from ovarian cancer patientsQ36622390
Mechanisms of transcoelomic metastasis in ovarian cancer.Q36643128
Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm.Q36914343
Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reductionQ36924865
Molecular pathogenesis and therapeutic targets in epithelial ovarian cancer.Q36945763
Ascites specific inhibition of CD1d-mediated activation of natural killer T cells.Q37177987
NKG2D ligands in tumor immunityQ37287179
Tumor invasion and metastasis: an imbalance of positive and negative regulation.Q37289935
Combining a symptoms index with CA 125 to improve detection of ovarian cancer.Q37324647
The temporal stability of the Symptom Index among women at high-risk for ovarian cancer.Q37329916
Epidemiology of ovarian cancerQ37358065
Multicellular spheroids in ovarian cancer metastases: Biology and pathology.Q37366009
Phase I active immunotherapy with combination of two chimeric, human epidermal growth factor receptor 2, B-cell epitopes fused to a promiscuous T-cell epitope in patients with metastatic and/or recurrent solid tumorsQ37412304
Decoy receptor 3 overexpression and immunologic tolerance in hepatocellular carcinoma (HCC) developmentQ38358028
Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancerQ39741066
Development of an ovarian cancer symptom index: possibilities for earlier detection.Q39777813
Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancerQ39796555
Priming and activation of human ovarian and breast cancer-specific CD8+ T cells by polyvalent Listeria monocytogenes-based vaccinesQ39799815
Memory and cellular immunity induced by a DNA vaccine encoding self antigen TPD52 administered with soluble GM-CSF.Q39890891
Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasisQ39915235
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.Q39959127
Oregovomab maintenance monoimmunotherapy does not improve outcomes in advanced ovarian cancerQ40019095
Correlation between expression of DcR3 on tumor cells and sensitivity to FasL.Q40029680
Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenograftsQ40041128
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.Q40111238
Phase I study of abagovomab in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer.Q40469093
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysisQ40552203
Ovarian carcinoma cells inhibit T cell proliferation: suppression of IL-2 receptor beta and gamma expression and their JAK-STAT signaling pathwayQ40596065
Development of a syngeneic mouse model for events related to ovarian cancerQ40888613
Immunotherapy of human ovarian carcinoma with OvaRex MAb-B43.13 in a human-PBL-SCID/BG mouse modelQ40959437
Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexityQ41033264
Pathology of ovarian cancer precursorsQ41070262
Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancerQ41114970
The E-cadherin/catenin complex in invasion and metastasisQ41117074
Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosisQ43774838
Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer.Q43779560
Papillary serous carcinoma of the peritoneumQ44099816
Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trialQ44426842
Effects of epidermal growth factor/hydrocortisone on the growth and differentiation of human ovarian surface epitheliumQ44878671
Characterization of the CA 125 antigen associated with human epithelial ovarian carcinomas.Q44986187
Factors affecting the completion of intraperitoneal chemotherapy in women with ovarian cancerQ45111172
Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.Q45728676
Tissue expression of CA 125 in benign and malignant lesions of ovary and fallopian tube: a comparison with CA 19-9 and CEA.Q45789637
Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy.Q46016693
Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor modelsQ46407253
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectobstetrics and gynaecologyQ80015
ovarian cancerQ172341
P304page(s)8
P577publication date2010-01-01
P1433published inJournal of Ovarian ResearchQ27721898
P1476titleThe detection, treatment, and biology of epithelial ovarian cancer
P478volume3

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cites work (P2860)
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