Mesothelin targeted cancer immunotherapy

scientific article

Mesothelin targeted cancer immunotherapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.EJCA.2007.08.028
P932PMC publication ID2265108
P698PubMed publication ID17945478
P5875ResearchGate publication ID5901116

P50authorRaffit HassanQ96951105
P2093author name stringMitchell Ho
P2860cites workBinding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesionQ24301956
Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancersQ24315965
Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumorsQ24673454
Stromelysin-1 and mesothelin are differentially regulated by Wnt-5a and Wnt-1 in C57mg mouse mammary epithelial cellsQ24797540
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activationQ28141319
Mesothelin: a new target for immunotherapyQ28268571
Detection and quantitation of serum mesothelin, a tumor marker for patients with mesothelioma and ovarian cancerQ28293019
Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomasQ30310974
Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.Q30670385
Improving antibody affinity by mimicking somatic hypermutation in vitroQ30724948
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).Q30781823
Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activityQ32140773
Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinomaQ33233449
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathwaysQ33814311
Mesothelin is not required for normal mouse development or reproductionQ33895649
A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancerQ34254918
Identification of novel human CTL epitopes and their agonist epitopes of mesothelinQ34313298
Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinomaQ34614377
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patientsQ36399737
What are the current best immunohistochemical markers for the diagnosis of epithelioid mesothelioma? A review and updateQ36631062
Listeria-based cancer vaccines that segregate immunogenicity from toxicityQ37535306
Localization of mesothelin in epithelial ovarian cancerQ38441572
Mesothelin expression in human lung cancerQ40164540
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing miceQ40245236
Pretargeted radioimmunotherapy of mesothelin-expressing cancer using a tetravalent single-chain Fv-streptavidin fusion proteinQ40401336
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapyQ40496032
Cytotoxic activity of the recombinant anti-mesothelin immunotoxin, SS1(dsFv)PE38, towards tumor cell lines established from ascites of patients with peritoneal mesotheliomas.Q40531731
A novel cytokine exhibiting megakaryocyte potentiating activity from a human pancreatic tumor cell line HPC-Y5.Q41494627
Frequent expression of the tumor antigen CAK1 in squamous-cell carcinomasQ41619004
Monoclonal Antibody K1 Reacts With Epithelial Mesothelioma but not With Lung AdenocarcinomaQ41636261
Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro.Q42808417
Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-cateninQ46511205
Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarraysQ47960817
Application of Mesothelin Immunostaining in Tumor DiagnosisQ50492362
Tumor-directed radiation and the immunotoxin SS1P in the treatment of mesothelin-expressing tumor xenografts.Q51790432
Value of mesothelin immunostaining in the diagnosis of mesothelioma.Q54769537
Immunotoxin therapy of cancerQ56454451
Mesothelin-family proteins and diagnosis of mesotheliomaQ57297479
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesotheliumQ67743629
Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleuraQ78841533
Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancersQ81038996
Humoral immune response to mesothelin in mesothelioma and ovarian cancer patientsQ81753024
Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitisQ82279314
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
P304page(s)46-53
P577publication date2008-01-01
P1433published inEuropean Journal of CancerQ332260
P1476titleMesothelin targeted cancer immunotherapy
P478volume44

Reverse relations

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