Clinical trials of vaccines for immunotherapy in pancreatic cancer

scientific article published on June 2011

Clinical trials of vaccines for immunotherapy in pancreatic cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1586/ERV.11.77
P698PubMed publication ID21692703

P2093author name stringJanet Plate
P2860cites workMesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancerQ24622837
Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II studyQ24652592
Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinomaQ47221022
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.Q47745236
Phase 1 trial of Wilms tumor 1 (WT1) peptide vaccine and gemcitabine combination therapy in patients with advanced pancreatic or biliary tract cancer.Q51528727
Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.Q51803685
Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma.Q52020454
PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine.Q53255741
Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutationQ56815463
Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic AdenocarcinomaQ56899396
Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activityQ59074350
Mesothelin targeted cancer immunotherapyQ24656242
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarraysQ28185685
Mesothelin: a new target for immunotherapyQ28268571
Tumor angiogenesisQ29614938
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlatesQ29620051
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouseQ29620396
Cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line metastatic pancreatic cancer: a multicentre phase II studyQ33383758
Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activationQ33887648
Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205Q34049250
Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).Q34049260
Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-rasQ34115737
Development of Ipilimumab: Contribution to a New Paradigm for Cancer ImmunotherapyQ34149569
Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cellsQ34304405
Mannan-MUC1-pulsed dendritic cell immunotherapy: a phase I trial in patients with adenocarcinoma.Q34492778
Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909.Q34508125
Focus on pancreas cancerQ34768641
Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.Q34875973
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activationQ34904065
The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational researchQ35000726
Autologous tumor vaccines processed to express alpha-gal epitopes: a practical approach to immunotherapy in cancerQ35810104
Development of the PANVAC-VF vaccine for pancreatic cancerQ36383786
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patientsQ36399737
Poxvirus-based vaccine therapy for patients with advanced pancreatic cancerQ36412657
PANVAC-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinomaQ36764939
Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines.Q36787548
Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancerQ36900726
Current immunotherapeutic strategies in pancreatic cancerQ37005912
MUC1 immunotherapy.Q37773241
Targeting mutated K-ras in pancreatic adenocarcinoma using an adjuvant vaccine.Q39850362
Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancerQ39981172
Effect of Cyclophosphamide on Immunological Control MechanismsQ40113295
PankoMab: a potent new generation anti-tumour MUC1 antibodyQ40314964
MUC‐1 Epithelial Tumor Mucin‐Based Immunity and Cancer VaccinesQ40433320
A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growthQ40692331
Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancerQ41705602
Increased immunogenicity of tumor-associated antigen, mucin 1, engineered to express alpha-gal epitopes: a novel approach to immunotherapy in pancreatic cancerQ43041616
Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancerQ43237571
Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapyQ45003964
Circulating anti-MUC1 IgG antibodies as a favorable prognostic factor for pancreatic cancerQ45205147
Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trialQ46852439
P433issue6
P921main subjectpancreatic cancerQ212961
immunotherapyQ1427096
P304page(s)825-836
P577publication date2011-06-01
P1433published inExpert Review of VaccinesQ15756339
P1476titleClinical trials of vaccines for immunotherapy in pancreatic cancer
P478volume10

Reverse relations

cites work (P2860)
Q28395823Adoptive T-cell transfer combined with a single low dose of total body irradiation eradicates breast tumors
Q34353635Combination treatment with comprehensive cryoablation and immunotherapy in metastatic hepatocellular cancer
Q40161224Prospective study of the safety and efficacy of a pancreatic cancer stem cell vaccine
Q38068234Recent progress in canine tumor vaccination: potential applications for human tumor vaccines
Q37606102Role of immune cells in pancreatic cancer from bench to clinical application: An updated review
Q40166620Safety and efficacy study of lung cancer stem cell vaccine
Q37710295The Association Between Chemoradiation-related Lymphopenia and Clinical Outcomes in Patients With Locally Advanced Pancreatic Adenocarcinoma.
Q57594208Vaccines in clinical trials: cancer

Search more.