Tumor angiogenesis

scientific article (publication date: 8 May 2008)

Tumor angiogenesis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1056/NEJMRA0706596
P8608Fatcat IDrelease_xben6afysngujeu6jnmhocusky
P3181OpenCitations bibliographic resource ID2489563
P932PMC publication ID4542009
P698PubMed publication ID18463380
P5875ResearchGate publication ID5389019

P2093author name stringKerbel RS
P2860cites workBlocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growthQ24293042
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vesselsQ24299513
Vasohibin as an endothelium-derived negative feedback regulator of angiogenesisQ24306415
G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cellsQ78312502
Blockade of the vascular endothelial growth factor-receptor 2 pathway inhibits the growth of human renal cell carcinoma, RBM1-IT4, in the kidney but not in the bone of nude miceQ79857937
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growthQ80212331
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibitionQ80376810
Vascular leukocytes contribute to tumor vascularizationQ80546906
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesisQ81277909
VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cellsQ82264553
Antiangiogenic therapy: a universal chemosensitization strategy for cancer?Q83854395
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicityQ24561642
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularizationQ24673319
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitorsQ24676378
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Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sproutingQ24685542
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Tumor angiogenesis: therapeutic implicationsQ27860595
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
A cell initiating human acute myeloid leukaemia after transplantation into SCID miceQ28131777
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasisQ28264314
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Sorafenib in advanced clear-cell renal-cell carcinomaQ28282767
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Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancerQ28376841
Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1Q28469224
Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2Q28570936
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapyQ29547379
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Clinical translation of angiogenesis inhibitorsQ34152769
Chemokines direct endothelial progenitors into tumor neovesselsQ34212748
Endogenous inhibitors of angiogenesis.Q34419511
Autocrine VEGF signaling is required for vascular homeostasisQ34443661
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Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.Q50754378
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Tumor-associated macrophages press the angiogenic switch in breast cancer.Q51984236
Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells.Q53921302
A cancer drug shows promise, at a price that many can't pay.Q54023421
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Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesisQ59276609
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Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity.Q35848435
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Vascular remodeling and clinical resistance to antiangiogenic cancer therapy.Q35943388
Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.Q36014526
Genes that distinguish physiological and pathological angiogenesisQ36087324
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacyQ36089148
Disrupting tumour blood vesselsQ36146900
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockadeQ36276765
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The multifaceted circulating endothelial cell in cancer: towards marker and target identification.Q36621435
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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.Q37594746
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Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.Q40228810
Granulocyte colony-stimulating factor promotes tumor angiogenesis via increasing circulating endothelial progenitor cells and Gr1+CD11b+ cells in cancer animal modelsQ40340358
Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-optionQ40511146
Increased plasma vascular endothelial growth factor (VEGF) as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies.Q40514698
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawalQ40848490
The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesisQ42411644
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanismQ44043571
Signaling vascular morphogenesis and maintenanceQ45058276
Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.Q45866300
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortiaQ46114146
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectangiogenesis inhibitorQ574834
neoplasmQ1216998
neovascularizationQ1281049
VEGF receptorsQ4356503
vascular endothelial growth factor AQ7916455
tumor angiogenesisQ110495869
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)2039-49
P577publication date2008-05-08
P1433published inThe New England Journal of MedicineQ582728
P1476titleTumor angiogenesis
P478volume358

Reverse relations

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Q44228500Cardio-oncology: it takes two to translate
Q35584182Cardiovascular safety of VEGF-targeting therapies: current evidence and handling strategies
Q39717717Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer
Q37474070Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer
Q39497289Celastrus orbiculatus extract inhibits tumor angiogenesis by targeting vascular endothelial growth factor signaling pathway and shows potent antitumor activity in hepatocarcinomas in Vitro and in Vivo
Q33913432Celecoxib decreases growth and angiogenesis and promotes apoptosis in a tumor cell line resistant to chemotherapy
Q37505664Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51.
Q57810087Cell death in cancer in the era of precision medicine
Q35603983Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis
Q35123591Cell-based quantification of molecular biomarkers in histopathology specimens
Q58575098Cellular and Molecular Heterogeneity Associated with Vessel Formation Processes
Q41251561Cellular signaling pathway alterations and potential targeted therapies for medullary thyroid carcinoma
Q37546027Cervical cancer therapy: current, future and anti-angiogensis targeted treatment
Q33525581Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma
Q38554663Changing paradigms in the systemic treatment of advanced cervical cancer
Q98385780Characteristic Blood-Perfusion Reduction of Walker 256 Tumor Induced by Diagnostic Ultrasound and Microbubbles
Q55463722Characteristics of tumour vessels in cytological squash smears of astrocytic tumours
Q57116617Characterization and potential roles of bone marrow-derived stromal cells in cancer development and metastasis
Q57185834Characterization of receptor binding kinetics for vascular endothelial growth factor-A using SPR
Q30438032Chemokines as mediators of neovascularization
Q38053441Chemotherapy: What is its role in meningioma?
Q38800593Chimeric Mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments
Q39687326Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance.
Q35078406Cilengitide-induced temporal variations in transvascular transfer parameters of tumor vasculature in a rat glioma model: identifying potential MRI biomarkers of acute effects
Q37780014Circulating endothelial and endothelial progenitor cells in non-small-cell lung cancer.
Q53420162Circulating endothelial cells in chronic lymphocytic leukemia: more evidence of disturbed angiogenesis.
Q50784041Circulating endothelial cells in patients with chronic lymphocytic leukemia: clinical-prognostic and biologic significance.
Q54628938Circulating perivascular progenitors: a target of PDGFR inhibition.
Q42546774Classifier of cross talk genes predicts the prognosis of hepatocellular carcinoma
Q36884393Clinical Trials of Antiangiogenesis Therapy in Recurrent/Persistent and Metastatic Cervical Cancer
Q34658366Clinical advances in the development of novel VEGFR2 inhibitors
Q42708261Clinical significance of pretreatment serum levels of VEGF and its receptors, IL- 8, and their prognostic value in type I and II endometrial cancer patients
Q37892591Clinical trials of vaccines for immunotherapy in pancreatic cancer
Q26785665Clinical utility of ramucirumab in advanced gastric cancer
Q39388167Coevolution of the tumor microenvironment revealed by quantum dot-based multiplexed imaging of hepatocellular carcinoma
Q83192661Colonic anastomosis and colonic polyp mucosal metastasis of signet ring cell gastric adenocarcinoma
Q33803564Combination antiangiogenic therapy in advanced breast cancer: a phase 1 trial of vandetanib, a VEGFR inhibitor, and metronomic chemotherapy, with correlative platelet proteomics
Q92945264Combination of Epigallocatechin-3-gallate and Silibinin: A Novel Approach for Targeting Both Tumor and Endothelial Cells
Q39320160Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis.
Q36684023Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma
Q57317511Combination therapy of radiofrequency ablation and bevacizumab monitored with power Doppler ultrasound in a murine model of hepatocellular carcinoma
Q90074156Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents
Q89791281Combining transcatheter arterial embolization with iodized oil containing Apatinib inhibits HCC growth and metastasis
Q34105997Comparative effectiveness of approved first-line anti-angiogenic and molecularly targeted therapeutic agents in the treatment of good and intermediate risk metastatic clear cell renal cell carcinoma
Q41231221Comparison between three oxaliplatin-based regimens with bevacizumab in patients with metastatic colorectal cancer
Q91658406Competing Fluid Forces Control Endothelial Sprouting in a 3-D Microfluidic Vessel Bifurcation Model
Q38717558Concepts in cardio-oncology: definitions, mechanisms, diagnosis and treatment strategies of cancer therapy-induced cardiotoxicity
Q38058289Concise review: genetically engineered stem cell therapy targeting angiogenesis and tumor stroma in gastrointestinal malignancy
Q27023510Contemporary use of bevacizumab in ovarian cancer
Q34341736Context dependent role of the CD36--thrombospondin--histidine-rich glycoprotein axis in tumor angiogenesis and growth
Q36100725Contrary effects of the receptor tyrosine kinase inhibitor vandetanib on constitutive and flow-stimulated nitric oxide elaboration in humans
Q44556811Controlled release of imatinib mesylate from PLGA microspheres inhibit craniopharyngioma mediated angiogenesis
Q47675953Controlling Differentiation of Stem Cells for Developing Personalized Organ-on-Chip Platforms.
Q36003149Coup d'Etat: an orphan takes control.
Q38166329Critical appraisal of ramucirumab (IMC-1121B) for cancer treatment: from benchside to clinical use.
Q26801289Critical evaluation of ramucirumab in the treatment of advanced gastric and gastroesophageal cancers
Q38840543Cryptotanshinone, a novel tumor angiogenesis inhibitor, destabilizes tumor necrosis factor-α mRNA via decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR.
Q93039741Current Development of Monoclonal Antibodies in Cancer Therapy
Q34204524Current approaches and recent developments in the management of head and neck paragangliomas
Q53225923Current opinion on bevacizumab on endometrial cancer treatment.
Q34198939Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model
Q38169761Current status of antiangiogenic therapies for glioblastomas
Q35742534Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs
Q58546808Cyclooxygenase-2 inhibition potentiates the efficacy of vascular endothelial growth factor blockade and promotes an immune stimulatory microenvironment in preclinical models of pancreatic cancer
Q37900650Cytokines in neuroblastoma: from pathogenesis to treatment.
Q35880529Cytoplasmic Accumulation of Heterogeneous Nuclear Ribonucleoprotein K Strongly Promotes Tumor Invasion in Renal Cell Carcinoma Cells
Q33603626DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting β-catenin Signaling to Induce Expression of VEGFA
Q40346499DLL4 as a predictor of pelvic lymph node metastasis and a novel prognostic biomarker in patients with early-stage cervical cancer
Q49932201Das infantile Hämangiom: Pathogenese und Wirkmechanismus von Propranolol
Q64079790Deciphering the Pharmacological Mechanism of the Herb in the Treatment of Nasopharyngeal Carcinoma by Integrating iTRAQ-Coupled 2-D LC-MS/MS Analysis and Network Investigation
Q35713658Deflection of vascular endothelial growth factor action by SS18-SSX and composite vascular endothelial growth factor- and chemokine (C-X-C motif) receptor 4-targeted therapy in synovial sarcoma
Q39456092Delta-like ligand 4-notch blockade and tumor radiation response
Q34427294Delta-like ligand 4: A predictor of poor prognosis in clear cell renal cell carcinoma
Q48541561Demonstration of DCE-MRI as an early pharmacodynamic biomarker of response to VEGF Trap in glioblastoma
Q50073578Design and characterization of MP0250, a tri-specific anti-HGF/anti-VEGF DARPin® drug candidate.
Q84529564Design, synthesis, and anti-proliferative evaluation of [1,1'-biphenyl]-4-ols as inhibitor of HUVEC migration and tube formation
Q41852958Detection of circulating vascular endothelial growth factor and matrix metalloproteinase-9 in non-small cell lung cancer using Luminex multiplex technology
Q30475052Determination of breast cancer response to bevacizumab therapy using contrast-enhanced ultrasound and artificial neural networks
Q39432968Development and Validation of a Histological Method to Measure Microvessel Density in Whole-Slide Images of Cancer Tissue
Q34300621Development of a Resistance-like Phenotype to Sorafenib by Human Hepatocellular Carcinoma Cells Is Reversible and Can Be Delayed by Metronomic UFT Chemotherapy
Q39411007Diabetes and Wound Angiogenesis
Q38062793Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?
Q43245707Did animal offer relevant model for Bevacizumab testing?
Q35053270Differential effects of drugs targeting cancer stem cell (CSC) and non-CSC populations on lung primary tumors and metastasis
Q35803027Differential macrophage programming in the tumor microenvironment
Q39092622Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis.
Q37507568Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer
Q37204589Dihydroartemisinin induces endothelial cell anoikis through the activation of the JNK signaling pathway.
Q39459741Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.
Q37260920Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism.
Q93166626Discovery of Pyrido[3',2':5,6]thiopyrano[4,3-d]pyrimidine-Based Antiproliferative Multikinase Inhibitors
Q64064629Discovery of Small Molecules that Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies
Q36212825Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy
Q30373777Disruption of Prostate Microvasculature by Combining Microbubble-Enhanced Ultrasound and Prothrombin.
Q52619579Disruption of tumor neovasculature by microbubble enhanced ultrasound: a potential new physical therapy of anti-angiogenesis.
Q34141587Dissecting the autocrine and paracrine roles of the CCR2-CCL2 axis in tumor survival and angiogenesis
Q38192670Do anti-angiogenic cancer therapies increase risk of significant weight loss?
Q36659012Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer.
Q42021890Does CD34 Staining Reflect the Angiogenic Process in the Bone Marrow? An Analysis of a Series of Chronic Myeloid Leukemia Patients
Q46193990Does serum soluble vascular endothelial growth factor levels have different importance in pediatric acute leukemia and malignant lymphoma patients?
Q39226994Dose dependent effects of cadmium on tumor angiogenesis.
Q33786674Downregulation of angiogenesis factors, VEGF and PDGF, after rapid IgE desensitization and oral immunotherapy in children with food allergy
Q37050403Dynamic contrast-enhanced MRI for monitoring antiangiogenic treatment: determination of accurate and reliable perfusion parameters in a longitudinal study of a mouse xenograft model
Q38171740Dysphonia induced by anti-angiogenic compounds
Q38160089EGFR and KRAS mutations, and ALK fusions: current developments and personalized therapies for patients with advanced non-small-cell lung cancer.
Q24310236EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF
Q38019814EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis
Q52149377Early biomarkers from dynamic contrast-enhanced magnetic resonance imaging to predict the response to antiangiogenic therapy in high-grade gliomas.
Q43201120Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes.
Q33947163Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells
Q36503239Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apoptosis and expression of vascular endothelial growth factor and basic fibroblast growth factor in human umbilical vein endothelial cells
Q31060162Effect of angiogenesis inhibitor bevacizumab on survival in patients with cancer: a meta-analysis of the published literature
Q53239742Effect of high salt diet on blood pressure and renal damage during vascular endothelial growth factor inhibition with sunitinib.
Q37126585Effect of increased body mass index (BMI) on time to tumour progression (TTP) in unresectable metastatic colorectal cancer (mCRC) patients treated with bevacizumab-based therapy.
Q37458674Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer
Q49693392Effective Treatment of Cytotoxic Agent Refractory Alpha-Fetoprotein-Producing Gastric Cancer with Ramucirumab: a Case Report and Review of the Literature
Q26826864Effects of novel angiogenesis inhibitors for the treatment of cancer on the cardiovascular system: focus on hypertension
Q34668740Effects of tetrahydrocurcumin on hypoxia-inducible factor-1α and vascular endothelial growth factor expression in cervical cancer cell-induced angiogenesis in nude mice.
Q90455818Efficacy and Safety of Apatinib Plus Vinorelbine in Patients With Wild-Type Advanced Non-Small Cell Lung Cancer After Second-Line Treatment Failure: A Nonrandomized Clinical Trial
Q28079362Efficacy and safety of angiogenesis inhibitors in advanced gastric cancer: a systematic review and meta-analysis
Q90400076Efficacy and safety of apatinib combined with chemotherapy for the treatment of advanced gastric cancer in the Chinese population: a systematic review and meta-analysis
Q38230556Efficacy of motesanib diphosphate in non-small-cell lung cancer
Q40600188Efficacy of the nanoparticle-drug conjugate CRLX101 in combination with bevacizumab in metastatic renal cell carcinoma: results of an investigator-initiated phase I-IIa clinical trial
Q33800886Efficient in vivo selection of a novel tumor-associated peptide from a phage display library
Q47855049Elevated serum levels of cardiovascular biomarkers are associated with progression of renal cancer
Q28536420Embedding synthetic microvascular networks in poly(lactic acid) substrates with rounded cross-sections for cell culture applications
Q58798211Emerging Medical Treatments for Meningioma in the Molecular Era
Q38065241Emerging VEGF-receptor inhibitors for colorectal cancer
Q45874449Emerging drugs for head and neck cancer
Q35098322Emerging drugs to treat squamous cell carcinomas of the head and neck
Q48171089Emerging enzymatic targets controlling angiogenesis in cancer: preclinical evidence and potential clinical applications
Q35914897Emerging insights into the molecular and cellular basis of glioblastoma
Q38132645Emerging paradigms in cardiomyopathies associated with cancer therapies
Q41837594Emerging role of multikinase inhibitors for refractory thyroid cancer
Q34660607Emerging therapeutic targets for synovial sarcoma
Q36519807Emerging treatments for choroidal metastases
Q39431959Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan
Q36821570Endocrine vasculatures are preferable targets of an antitumor ineffective low dose of anti-VEGF therapy
Q39415229Endocytic adaptor protein epsin is elevated in prostate cancer and required for cancer progression
Q55506580Endogenous Matrix-Derived Inhibitors of Angiogenesis.
Q45901060Endoglin and activin receptor-like kinase 1 heterozygous mice have a distinct pulmonary and hepatic angiogenic profile and response to anti-VEGF treatment.
Q58093810Endoplasmic reticulum resident oxidase ERO1-Lalpha promotes hepatocellular carcinoma metastasis and angiogenesis through the S1PR1/STAT3/VEGF-A pathway
Q42047188Endostatin and anastellin inhibit distinct aspects of the angiogenic process
Q38821715Endostatin exerts radiosensitizing effect in non-small cell lung cancer cells by inhibiting VEGFR2 expression
Q28547399Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis
Q36499423Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism
Q33680346Endothelial Membrane Remodeling Is Obligate for Anti-Angiogenic Radiosensitization during Tumor Radiosurgery
Q35255024Endothelial cell tube formation assay for the in vitro study of angiogenesis
Q33592677Endothelial cell-derived interleukin-6 regulates tumor growth
Q34777219Endothelial cell-initiated extravasation of cancer cells visualized in zebrafish
Q34473290Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties
Q36498075Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling
Q35857778Endothelial progenitor cells carrying monocyte markers are selectively abnormal in type 1 diabetic patients with early retinopathy
Q37957761Endothelial progenitor cells: current issues on characterization and challenging clinical applications
Q38930761Engineered Microvessels for the Study of Human Disease
Q48822702Enhancement of Antiangiogenic Efficacy of Iron(II) Complex by Selenium Substitution
Q97543137Eosinophil and lymphocyte counts predict bevacizumab response and survival in recurrent glioblastoma
Q37153834EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance
Q38207484Epidermal growth factor receptor signalling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors
Q33619401Epithelial membrane protein-2 (EMP2) activates Src protein and is a novel therapeutic target for glioblastoma
Q39836194Epithelial-mesenchymal transition of ovarian tumor cells induces an angiogenic monocyte cell population
Q28307353Epsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer Progression
Q38708078Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
Q90701568Erythropoietin in tumor angiogenesis
Q36685121Essential role for endocytosis in the growth factor-stimulated activation of ERK1/2 in endothelial cells.
Q64254117Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure
Q28539181Evaluating the potential bioactivity of a novel compound ER1626
Q37965053Evaluation of treatment response in patients with metastatic renal cell carcinoma: role of state-of-the-art cross-sectional imaging
Q34470473Evaluation of tumor microenvironment in an animal model using a nanoparticle contrast agent in computed tomography imaging
Q38081233Everolimus in colorectal cancer
Q50878183Evidence for angiogenesis-independent contribution of VEGFR1 (FLT1) in gastric cancer recurrence.
Q21145736Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent
Q37862235Evolving strategies: future treatment of glioblastoma
Q37501570Exercise intolerance in cancer and the role of exercise therapy to reverse dysfunction.
Q64234892Exogenous sickle erythrocytes combined with vascular disruption trigger disseminated tumor vaso-occlusion and lung tumor regression
Q38709057Exosomes from Plasmodium-infected hosts inhibit tumor angiogenesis in a murine Lewis lung cancer model
Q39120436Exploring and challenging the network of angiogenesis.
Q39497632Exploring the concept of "inflammatory angiogenesis" in keratocystic odontogenic tumor
Q38319730Exploring the therapeutic rationale for angiogenesis blockade in cervical cancer
Q42376380Expression and association of VEGF-Notch pathways in infantile hemangiomas
Q46042271Expression and correlation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis
Q39697040Expression and prognostic significance of placental growth factor in hepatocellular carcinoma and peritumoral liver tissue
Q33951007Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer
Q37158416Expression of VEGF, its receptors, and HIF-1α in Dupuytren's disease
Q44753855Expression of tumor suppressor gene ING4 in ovarian carcinoma is correlated with microvessel density
Q33410553Expression patterns of RelA and c-mip are associated with different glomerular diseases following anti-VEGF therapy
Q95660964Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells
Q34129824FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol
Q34439734Fast rearrangement of the neuronal growth cone's actin cytoskeleton following VEGF stimulation
Q38799374Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties.
Q45370083Feasibility study of CT perfusion imaging for prostate carcinoma
Q54634525Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib.
Q39725148Firefly luciferase-based dynamic bioluminescence imaging: a noninvasive technique to assess tumor angiogenesis
Q38213500First-line and maintenance therapy for ovarian cancer: current status and future directions
Q33591948Five-year survival of metastatic pancreatic carcinoma: a study of courage and hope
Q35866398Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization.
Q24314412Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo
Q51366224Food increased the bioavailability of BMS-690514, an orally active EGFR/HER2/VEGF receptor kinase inhibitor, in healthy subjects.
Q37174213Foxc2 transcription factor as a regulator of angiogenesis via induction of integrin beta3 expression
Q24653645Foxc2 transcription factor: a newly described regulator of angiogenesis
Q26827148From sprouting angiogenesis to erythrocytes generation by cancer stem cells: evolving concepts in tumor microcirculation
Q37326863Future of targeted agents in metastatic colorectal cancer
Q35230245G-CSF supplementation with chemotherapy can promote revascularization and subsequent tumor regrowth: prevention by a CXCR4 antagonist
Q37149710G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
Q24631249GLO1-A novel amplified gene in human cancer
Q35597134Gas challenge-blood oxygen level-dependent (GC-BOLD) MRI in the rat Novikoff hepatoma model
Q36629538Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications
Q36764284Gene regulation by RNA binding proteins and microRNAs in angiogenesis
Q58362653Gene therapy in peripheral artery disease
Q55058836Gene-expression profiles correlate with the efficacy of anti-EGFR therapy and chemotherapy for colorectal cancer.
Q34645999General aspects of colorectal cancer
Q38565301Genetic markers of recurrence in colorectal cancer
Q84340559Genetic pathways linking hemostasis and cancer
Q41945502Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency
Q33620506Genetics of glioblastoma: a window into its imaging and histopathologic variability
Q29417061Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3
Q59465394Genomically personalized therapy in head and neck cancer
Q38700575Ginseng Metabolites on Cancer Chemoprevention: An Angiogenesis Link?
Q42835218Glioma cells enhance angiogenesis and inhibit endothelial cell apoptosis through the release of exosomes that contain long non-coding RNA CCAT2.
Q39959730Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotype
Q58883666Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis
Q39030742Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation
Q37962333HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
Q35097628HIF-1α and HIF-2α: siblings in promoting angiogenesis of residual hepatocellular carcinoma after high-intensity focused ultrasound ablation
Q44102393HIF-1α expression correlates with cellular apoptosis, angiogenesis and clinical prognosis in rectal carcinoma
Q96231688Heart-derived fibroblasts express LYPD-1 and negatively regulate angiogenesis in rat
Q33526297Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells
Q45128040Hemorrhagic events in cancer patients treated with aflibercept: a meta-analysis
Q55224564High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer.
Q54569303High expression of delta-like ligand 4 predicts poor prognosis after curative resection for pancreatic cancer.
Q40421447High-Resolution Intravital Microscopy of Tumor Angiogenesis
Q35312455High-field small animal magnetic resonance oncology studies.
Q54631831Hippocampal Neurogenesis after Traumatic Brain Injury Is Mediated by Vascular Endothelial Growth Factor Receptor-2 and the Raf/MEK/ERK Cascade
Q34399444Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies
Q42321106Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation
Q35767922Host-derived pericytes and Sca-1+ cells predominate in the MART-1- stroma fraction of experimentally induced melanoma
Q37291680Host-derived tumor endothelial marker 8 promotes the growth of melanoma
Q35588157How platelets safeguard vascular integrity
Q34640644Hyperplasia of pericytes is one of the main characteristics of microvascular architecture in malignant glioma
Q37996791Hypoxia control to normalize pathologic angiogenesis: potential role for endothelial precursor cells and miRNAs regulation
Q42426199Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies
Q37428993Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model
Q35825993Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma
Q38078802Hypoxia-regulated microRNAs in human cancer
Q39530204IL-3 is a novel target to interfere with tumor vasculature
Q35987440IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma
Q35043619Identification and characterization of angiogenesis targets through proteomic profiling of endothelial cells in human cancer tissues
Q35165550Identification and expression of troponin T, a new marker on the surface of cultured tumor endothelial cells by aptamer ligand
Q37338152Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay
Q40867070Identification of a Peptide from In vivo Bacteriophage Display with Homology to EGFL6: A Candidate Tumor Vasculature Ligand in Breast Cancer
Q33364892Identification of a characteristic vascular belt zone in human colorectal cancer
Q39390836Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array
Q48128395Immune cells regulate VEGF signalling via release of VEGF and antagonistic soluble VEGF receptor-1.
Q35138135Immunity and immune suppression in human ovarian cancer
Q37898427Immunochemistry and lung cancer: application in diagnosis, prognosis and targeted therapy
Q37417622Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research
Q33357295Immunotherapy for recurrent ovarian cancer: a further piece of the puzzle or a striking strategy?
Q37280829Immunotherapy in colorectal cancer
Q35840873Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice
Q37825180In pursuit of new anti-angiogenic therapies for cancer treatment
Q27301905In vitro and in vivo anti-angiogenic activities of Panduratin A
Q90568470In vitro and in vivo apatinib inhibits vasculogenic mimicry in melanoma MUM-2B cells
Q37222836In vitro angiogenesis induced by tumor-endothelial cell co-culture in bilayered, collagen I hydrogel bioengineered tumors
Q38480926In vivo passage of human prostate cancer cells in mice results in stable gene expression changes affecting numerous cancer-associated biological processes
Q36149661In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued
Q37662388Incidence and relative risk of hemorrhagic events associated with ramucirumab in cancer patients: a systematic review and meta-analysis
Q34445829Incidence and risk of proteinuria with aflibercept in cancer patients: a meta-analysis
Q35757896Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas
Q44864734Increase in circulating endothelial progenitor cells predicts response in patients with advanced non-small-cell lung cancer
Q81985539Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors
Q36642689Increased expression of placental growth factor in high-grade endometrial carcinoma
Q55425422Indirect comparison of efficacy and safety between immune checkpoint inhibitors and antiangiogenic therapy in advanced non-small-cell lung cancer.
Q26776198Individualized treatment of gastric cancer: Impact of molecular biology and pathohistological features
Q42183046Induction of Bv8 expression by granulocyte colony-stimulating factor in CD11b+Gr1+ cells: key role of Stat3 signaling.
Q37194653Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation
Q47386049Infantile hemangioma: pathogenesis and mechanisms of action of propranolol
Q34443672Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China
Q40372513Influence of Exposure to Chronic Persistent Low-Dose Ionizing Radiation on the Tumor Biology of Clear-Cell Renal-Cell Carcinoma. An Immunohistochemical and Morphometric Study of Angiogenesis and Vascular Related Factors
Q37577918Influence of obesity on breast cancer receptor status and prognosis
Q37854731Influence of the tumor microenvironment on angiogenesis
Q33959754Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors
Q37958925Inhibition of angiogenesis and the angiogenesis/invasion shift
Q93087611Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor-based immunotherapy
Q36476333Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis
Q33915046Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth
Q38284055Inhibition of the VEGF signalling pathway and glomerular disorders.
Q42051818Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo
Q26859210Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
Q34658016Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model
Q55643012Inhibitory Effects of Arsenic Trioxide and Thalidomide on Angiogenesis and Vascular Endothelial Growth Factor Expression in Leukemia Cells
Q34152009Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
Q28483727Insufficient radiofrequency ablation promotes angiogenesis of residual hepatocellular carcinoma via HIF-1α/VEGFA
Q42025842Insufficient radiofrequency ablation promotes human hepatoma SMMC7721 cell proliferation by stimulating vascular endothelial growth factor overexpression
Q53068289Integrated ¹⁸F-FDG PET/perfusion CT for the monitoring of neoadjuvant chemoradiotherapy in rectal carcinoma: correlation with histopathology.
Q38341324Integration of bevacizumab with chemotherapy doublets for advanced cervical cancer
Q41670949Integrins as Therapeutic Targets: Successes and Cancers.
Q35446009Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses
Q35627827Intratumoral myeloid cells regulate responsiveness and resistance to antiangiogenic therapy.
Q33860350Intravitreal itraconazole inhibits laser-induced choroidal neovascularization in rats.
Q41928551Investigation of inhibitory effects on EPC-mediated neovascularization by different bisphosphonates for cancer therapy
Q38340008Investigational therapies currently in Phase II clinical trials for the treatment of pelvic serous carcinomas.
Q37826096Invited review: decoding the microRNA response to hypoxia.
Q39658278Involvement of Osteopontin in the Matrix-Degrading and Proangiogenic Changes Mediated by Nicotine in Pancreatic Cancer Cells
Q42643167Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway.
Q24297342Isolation of a small vasohibin-binding protein (SVBP) and its role in vasohibin secretion
Q35966791Issues regarding improving the impact of antiangiogenic drugs for the treatment of breast cancer
Q28544728JSI-124 suppresses invasion and angiogenesis of glioblastoma cells in vitro
Q49309017Kaempferol Inhibits Angiogenesis by Suppressing HIF-1α and VEGFR2 Activation via ERK/p38 MAPK and PI3K/Akt/mTOR Signaling Pathways in Endothelial Cells
Q35760920Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC).
Q51375392Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.
Q89907643Lentivirus-Mediated VEGF Knockdown Suppresses Gastric Cancer Cell Proliferation and Tumor Growth in vitro and in vivo
Q38702994Lenvatinib: a potential breakthrough in advanced hepatocellular carcinoma?
Q57789067LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning
Q47417663Lipocalin-type prostaglandin D synthase-derived PGD2 attenuates malignant properties of tumor endothelial cells
Q91782756Lipoplex-based targeted gene therapy for the suppression of tumours with VEGFR expression by producing anti-angiogenic molecules
Q35213093Live cell integrated surface plasmon resonance biosensing approach to mimic the regulation of angiogenic switch upon anti-cancer drug exposure
Q47170227LncRNA SUMO1P3 drives colon cancer growth, metastasis and angiogenesis
Q33623357Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
Q42366666Long non-coding RNAs associated with non-small cell lung cancer
Q36782557Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways
Q47181473Long-Term Effects of Weight Loss and Exercise on Biomarkers Associated with Angiogenesis
Q37435219Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models
Q38027711Lung cancer: microRNA and target database
Q35832959Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor formation by miR-16.
Q37057680Lymphatic endothelial cells support tumor growth in breast cancer
Q37821374Lymphocyte subpopulation and dendritic cell phenotyping during antineoplastic therapy in human solid tumors
Q38134562Lysyl oxidase in colorectal cancer
Q28280138Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis
Q42368143MEF2 transcription factors are key regulators of sprouting angiogenesis
Q39736118MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
Q47112808MP0250, a VEGF and HGF neutralizing DARPin® molecule shows high anti-tumor efficacy in mouse xenograft and patient-derived tumor models.
Q37955105Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.
Q50266714Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression
Q52682124Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy.
Q47773621Major Challenges and Potential Microenvironment-Targeted Therapies in Glioblastoma.
Q37363751Malignant cell-derived PlGF promotes normalization and remodeling of the tumor vasculature
Q36170252Management of antiangiogenic therapy-induced hypertension
Q33849034Management of stage IV rectal cancer: palliative options
Q37621006Managing tumor angiogenesis: lessons from VEGF-resistant tumors and wounds
Q41437410Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B.
Q82415696Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1
Q49476941Mechanism of the anti-angiogenic effect of Avemar on tumor cells
Q34972161Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates
Q38233448Medical management of meningiomas
Q37785808Medical therapies for meningiomas
Q38683133Medullary Thyroid Cancer: Clinical Characteristics and New Insights into Therapeutic Strategies Targeting Tyrosine Kinases
Q35038893Medullary thyroid carcinoma: molecular signaling pathways and emerging therapies
Q42631326Melanoma topology reveals a stem-like phenotype that promotes angiogenesis.
Q82973923Meta-analysis of the association between VEGF-634 G>C and risk of malignancy based on 23 case-control studies
Q92522555Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation
Q57490984Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial
Q37763502Metronomic chemotherapy: new rationale for new directions
Q36210881MiR-101 targets DUSP1 to regulate the TGF-β secretion in sorafenib inhibits macrophage-induced growth of hepatocarcinoma
Q46131735MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression
Q47118717MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling
Q43560853MicroRNA-144-3p suppresses tumor growth and angiogenesis by targeting SGK3 in hepatocellular carcinoma
Q39184127MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42.
Q33918344MicroRNA-22 regulates hypoxia signaling in colon cancer cells
Q47616223MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway
Q84598420MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression
Q34422270MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling
Q38247982MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer.
Q37363641MicroRNAs: opening a new vein in angiogenesis research.
Q36520345MicroRNA‑126 inhibits proliferation and metastasis by targeting pik3r2 in prostate cancer
Q34165754Microfluidic culture models of tumor angiogenesis
Q48443748Microvessel density is high in clear-cell renal cell carcinomas of Ukrainian patients exposed to chronic persistent low-dose ionizing radiation after the Chernobyl accident
Q36766681Mifepristone improves chemo-radiation response in glioblastoma xenografts.
Q34562257Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies
Q38514734Modeling and analyzing gene co-expression in hepatocellular carcinoma using actor-semiotic networks and centrality signatures.
Q42132001Modeling of growth factor-receptor systems from molecular-level protein interaction networks to whole-body compartment models
Q34383803Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues
Q37039546Molecular MR imaging of neovascular progression in the Vx2 tumor with αvβ3-targeted paramagnetic nanoparticles
Q92945523Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco-2 Cells
Q92835893Molecular biomarker-guided anti-angiogenic targeted therapy for malignant glioma
Q34089123Molecular diversity of VEGF-A as a regulator of its biological activity.
Q38168618Molecular markers and targeted therapies for adrenocortical carcinoma
Q94452251Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines
Q36500108Molecular targeting of liposomal nanoparticles to tumor microenvironment
Q37736281Molecular therapeutic targets for glioma angiogenesis
Q38272728Molecularly targeted therapies for recurrent glioblastoma: current and future targets
Q38002719Molecularly targeted therapies in cervical cancer. A systematic review
Q37861547Molecularly targeted therapy for metastatic colon cancer: proven treatments and promising new agents
Q33740232Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab
Q37142916Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways
Q34774917Morpholino-Mediated Isoform Modulation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) Reduces Colon Cancer Xenograft Growth
Q36335923Motif mimetic of epsin perturbs tumor growth and metastasis
Q39203569Mouse tumor vasculature expresses NKG2D ligands and can be targeted by chimeric NKG2D-modified T cells.
Q37086837Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancer
Q38645392Multi-parametric profiling of renal cell, colorectal, and ovarian cancer identifies tumour-type-specific stroma phenotypes and a novel vascular biomarker.
Q38119471Multifunctional nanomicellar systems for delivering anticancer drugs.
Q26821959Multikinase inhibitors in the treatment of thyroid cancer: specific role of lenvatinib
Q37404422Multiscale models of breast cancer progression
Q37758250Myeloid cells in the tumor microenvironment: modulation of tumor angiogenesis and tumor inflammation.
Q57283011NCI 8628: a randomized phase 2 study of ziv-aflibercept and high-dose interleukin 2 or high-dose interleukin 2 alone for inoperable stage III or IV melanoma
Q37043370NGR-TNF, a novel vascular-targeting agent, does not induce cytokine recruitment of proangiogenic bone marrow-derived cells
Q90185375NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma
Q39440633NUB1, an interferon-inducible protein, mediates anti-proliferative actions and apoptosis in renal cell carcinoma cells through cell-cycle regulation
Q38933699Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?
Q37695537Natriuretic peptide receptor A signaling regulates stem cell recruitment and angiogenesis: a model to study linkage between inflammation and tumorigenesis.
Q41383985Neovascularization in Glioblastoma: Current Pitfall in Anti-angiogenic therapy
Q90060268Network Pharmacology-based Investigation of the Underlying Mechanism of Panax Notoginseng Treatment of Diabetic Retinopathy
Q33873686Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma
Q42719160Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons
Q37503510Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching
Q90292756New Insights Into Implementation of Mesenchymal Stem Cells in Cancer Therapy: Prospects for Anti-angiogenesis Treatment
Q37752435New anti-angiogenic strategies in pediatric solid malignancies: agents and biomarkers of a near future
Q24619151New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer
Q49800025New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications
Q34224278New insights into the treatment of multiple myeloma with histone deacetylase inhibitors
Q33956040New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab.
Q26739049New trends in molecular and cellular biomarker discovery for colorectal cancer
Q34086332New vessel formation in peritumoral area of squamous cell carcinoma of the head and neck
Q38059265Nintedanib (BIBF 1120) for IPF: a tomorrow therapy?
Q47160725Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3.
Q34309479Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways
Q52665696Non-angiogenic tumours and their influence on cancer biology.
Q37036792Nonsurgical management of cervical cancer: locally advanced, recurrent, and metastatic disease, survivorship, and beyond
Q39202040Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways
Q47303044Notch transactivates Rheb to maintain the multipotency of TSC-null cells
Q33745300Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth
Q28546583Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays
Q37325086Novel anti-angiogenic therapies for malignant gliomas
Q41897121Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma.
Q38714205Novel roles of folic acid as redox regulator: Modulation of reactive oxygen species sinker protein expression and maintenance of mitochondrial redox homeostasis on hepatocellular carcinoma
Q38221292Novel treatments for head and neck squamous cell carcinoma: preclinical identification and clinical investigation
Q47701879Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production.
Q38107793Oncogenes and angiogenesis: a way to personalize anti-angiogenic therapy?
Q38113988Optimal management of Ewing sarcoma family of tumors: recent developments in systemic therapy
Q35882341Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin
Q33441574Outcomes and prognoses of patients with ovarian cancer using bevacizumab: 6-year experience in a tertiary care hospital of northern Taiwan
Q26749333Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction
Q38004740Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
Q34165780Oxygen-controlled three-dimensional cultures to analyze tumor angiogenesis
Q33778804P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
Q39433494PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Q34122706PLD1-dependent PKCgamma activation downstream to Src is essential for the development of pathologic retinal neovascularization.
Q37650308Palliative treatment of unresectable metastatic colorectal cancer
Q41876722Pan-PPAR Agonist, Bezafibrate, Restores Angiogenesis in Hindlimb Ischemia in Normal and Diabetic Rats.
Q28535447Paradoxical regulation of hypoxia inducible factor-1α (HIF-1α) by histone deacetylase inhibitor in diffuse large B-cell lymphoma
Q37730633Paramagnetic and fluorescent liposomes for target-specific imaging and therapy of tumor angiogenesis.
Q37974693Pazopanib for the treatment of breast cancer
Q28269229Pazopanib in the treatment of soft tissue sarcoma
Q52672956Pazopanib radio-sensitization of human sarcoma tumors.
Q37550249Perfusion computed tomography in colorectal cancer: protocols, clinical applications and emerging trends.
Q24595357Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression
Q47128300Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis
Q37730440Pharmaco-epigenomics: discovering therapeutic approaches and biomarkers for cancer therapy
Q26996793Pharmacogenetic biomarkers for the prediction of response to antiangiogenic treatment
Q64983729Pharmacokinetics, Biodistribution, and Anti-Angiogenesis Efficacy of Diamino Propane Tetraiodothyroacetic Acid-conjugated Biodegradable Polymeric Nanoparticle.
Q35108333Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy
Q37401839Phase I safety, pharmacokinetic, and pharmacodynamic study of ENMD-2076, a novel angiogenic and Aurora kinase inhibitor, in patients with advanced solid tumors
Q33627763Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors.
Q90449579Phase II evaluation of dalantercept in the treatment of persistent or recurrent epithelial ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study
Q91719723Phase II trial of paclitaxel, carboplatin, and bevacizumab for advanced or recurrent cervical cancer
Q37234829Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor-Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance)
Q64230340Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line
Q54595475Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of β-catenin transcriptional activity.
Q36944511Pilot study of (89)Zr-bevacizumab positron emission tomography in patients with advanced non-small cell lung cancer
Q38743706PlGF and VEGF-A Regulate Growth of High-Risk MYCN-Single Copy Neuroblastoma Xenografts via Different Mechanisms.
Q36268182PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors
Q38881266Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis.
Q27026940Positron emission tomography to assess hypoxia and perfusion in lung cancer
Q36024383Post-translational regulated and hypoxia-responsible VEGF plasmid for efficient secretion
Q33557565Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole
Q34128953Potential relevance of bell-shaped and u-shaped dose-responses for the therapeutic targeting of angiogenesis in cancer
Q54542173Potentially functional genetic variants in KDR gene as prognostic markers in patients with resected colorectal cancer.
Q34388847Practicing pathology in the era of big data and personalized medicine
Q35797850Preoperative platelet-lymphocyte ratio is superior to neutrophil-lymphocyte ratio as a prognostic factor for soft-tissue sarcoma
Q39046994Primary tumor versus metastasis: new experimental models for studies on cancer cell homing and metastasis in melanoma
Q43950404Primary tumorectomy promotes angiogenesis and pulmonary metastasis in osteosarcoma-bearing nude mice
Q39336606Pristimerin, a triterpenoid, inhibits tumor angiogenesis by targeting VEGFR2 activation.
Q36520616Profile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer
Q26775134Profile of nintedanib in the treatment of solid tumors: the evidence to date
Q41869300Profiling of microRNAs in AML cells following overexpression or silencing of the VEGF gene
Q38308001Prognostic and predictive role of vascular endothelial growth factor polymorphisms in breast cancer
Q35664735Prognostic angiogenic markers (endoglin, VEGF, CD31) and tumor cell proliferation (Ki67) for gastrointestinal stromal tumors
Q84801828Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer: coexpression of Notch-1 and vascular endothelial growth factor-A predicts poor survival
Q36241849Prognostic value of circulating endothelial cells in non-small cell lung cancer patients: a systematic review and meta-analysis
Q50358087Prognostic value of endoglin-assessed microvessel density in cancer patients: a systematic review and meta-analysis
Q51501402Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells.
Q42404762Proliferation and tissue remodeling in cancer: the hallmarks revisited
Q99212442Protein kinase C inhibitor anchored BRD4 PROTAC PEGylated nanoliposomes for the treatment of vemurafenib-resistant melanoma
Q39512060Protein kinase CK2 promotes cancer cell viability via up-regulation of cyclooxygenase-2 expression and enhanced prostaglandin E2 production
Q48538797Protein neddylation and its alterations in human cancers for targeted therapy
Q36953182Quinazoline derivative compound (11d) as a novel angiogenesis inhibitor inhibiting VEGFR2 and blocking VEGFR2-mediated Akt/mTOR /p70s6k signaling pathway
Q38814218RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature
Q37804904Radioimmunotherapy of Solid Tumors: Searching for the Right Target
Q33605773Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting
Q51651776Raiders of the lost mark - endothelial cells and their role in transplantation for hematologic malignancies.
Q92635779Ramucirumab and GSK1838705A Enhance the Inhibitory Effects of Low Concentration Sorafenib and Regorafenib Combination on HCC Cell Growth and Motility
Q38826507Ramucirumab for the treatment of gastric cancers, colorectal adenocarcinomas, and other gastrointestinal malignancies.
Q26745418Ramucirumab in metastatic colorectal cancer: evidence to date and place in therapy
Q38842754Ramucirumab: A vascular endothelial growth factor receptor-2 inhibitor with activity in several malignancies
Q34446310Ramucirumab: preclinical research and clinical development.
Q30438696Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents
Q38252759Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors.
Q38108392Recent advances in the treatment of metastatic renal cell carcinoma
Q58756849Recent advances in understanding the complexities of metastasis
Q21092930Recent advances of novel targeted therapy in non-small cell lung cancer
Q64103672Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
Q58607138Receptor Tyrosine Kinase-Targeted Cancer Therapy
Q64069367Recombinant RGD-disintegrin DisBa-01 blocks integrin αβ and impairs VEGF signaling in endothelial cells
Q47869837Recombinant protein rMBP-NAP restricts tumor progression by triggering antitumor immunity in mouse metastatic lung cancer
Q50277288Red Raspberry Phenols Inhibit Angiogenesis: A Morphological and Subcellular Analysis Upon Human Endothelial Cells
Q37301807Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma
Q33791749Regulation of ocular angiogenesis by Notch signaling: implications in neovascular age-related macular degeneration.
Q42288643Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma
Q28513991Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis
Q64375116Regulation of vascularization by hypoxia-inducible factor 1
Q26991865Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment
Q37334087Repurposing the Clinically Efficacious Antifungal Agent Itraconazole as an Anticancer Chemotherapeutic
Q52579594Resistance to Anti-Angiogenic Therapy in Cancer-Alterations to Anti-VEGF Pathway.
Q98291421Resistance to Anti-angiogenic Therapies: A Mechanism Depending on the Time of Exposure to the Drugs
Q39008859Resistance to Targeted Therapies in Renal Cancer: The Importance of Changing the Mechanism of Action.
Q37947911Response to anti-angiogenesis: an ever changing feature
Q37669383Retreatment with bevacizumab in patients with gynecologic malignancy is associated with clinical response and does not increase morbidity
Q93113434Revascularization after angiogenesis inhibition favors new sprouting over abandoned vessel reuse
Q81890232Rhinitis and epistaxis in patients treated by anti-angiogenic therapy
Q42158334RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA.
Q37917796Risk of anti-EGFR monoclonal antibody-related hypomagnesemia: systematic review and pooled analysis of randomized studies
Q58729601Risk of bleeding associated with antiangiogenic monoclonal antibodies bevacizumab and ramucirumab: a meta-analysis of 85 randomized controlled trials
Q36301449Risk of hemoptysis in patients with resected squamous cell and other high-risk lung cancers treated with adjuvant bevacizumab
Q35691234Risk of treatment-related mortality with sorafenib in cancer patients: a meta-analysis of 20 randomly controlled trials : Risk of sorafenib-associated death
Q42433181Risks associated with sunitinib use and monitoring to improve patient outcomes
Q48365671Role for cytotoxic chemotherapy in patients with recurrent glioblastoma progressing on bevacizumab: a retrospective case series
Q50586476Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer.
Q89835342Role of VEGFs/VEGFR-1 Signaling and its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models
Q37651091Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis
Q34254595Role of pancreatic stellate cells in pancreatic cancer metastasis.
Q33352793Role of placenta growth factor in cancer and inflammation
Q38399886Role of platelet derived growth factor receptor (PDGFR) over-expression and angiogenesis in ependymoma
Q39552934Role of the EGFR ligand/receptor system in the secretion of angiogenic factors in mesenchymal stem cells
Q37228059Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies
Q33740510SHARP1 suppresses angiogenesis of endometrial cancer by decreasing hypoxia-inducible factor-1α level
Q39521060SKLB610: a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo
Q39521937SPIO-RGD nanoparticles as a molecular targeting probe for imaging tumor angiogenesis using synchrotron radiation
Q36394326STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
Q36860502Safety and efficacy of bevacizumab with hypofractionated stereotactic irradiation for recurrent malignant gliomas
Q38066186Safety and efficacy of sunitinib in patients with unresectable pancreatic neuroendocrine tumors
Q38824719Safety of available treatment options for renal cell carcinoma
Q37903602Safety of bevacizumab in patients with metastatic breast cancer
Q35983858Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis
Q38709612Salinomycin exhibits anti-angiogenic activity against human glioma in vitro and in vivo by suppressing the VEGF-VEGFR2-AKT/FAK signaling axis
Q28077612Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses
Q34477717ScFv anti-heparan sulfate antibodies unexpectedly activate endothelial and cancer cells through p38 MAPK: implications for antibody-based targeting of heparan sulfate proteoglycans in cancer
Q36059674Selective blockade of tumor angiogenesis
Q34682223Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors
Q38546474Selective use of vandetanib in the treatment of thyroid cancer
Q28650150Semantically linking in silico cancer models
Q38161405Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression
Q39334060Serotonin activates angiogenic phosphorylation signaling in human endothelial cells
Q34606479Serum vascular endothelial growth factor and fibronectin predict clinical response to high-dose interleukin-2 therapy
Q35848075Short-term anti-vascular endothelial growth factor treatment elicits vasculogenic mimicry formation of tumors to accelerate metastasis
Q45885224Shortened ALK1 regulatory fragment maintains a specific activity in arteries feeding ischemic tissues
Q27324518Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response
Q54578853Significance of heparanase-1 and vascular endothelial growth factor in adrenocortical carcinoma angiogenesis: potential for therapy.
Q42263067Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic therapy with clinically available safe agents
Q33351178Solving the puzzle of metastasis: the evolution of cell migration in neoplasms
Q47126334Sorafenib Improves Survival in Metastatic Hepatocellular Carcinoma: A Case Report
Q51929209Spheroid-based human endothelial cell microvessel formation in vivo.
Q37655585State of the art in anti-cancer mAbs.
Q38046514Strategies for improving the clinical benefit of antiangiogenic drug based therapies for breast cancer
Q38015229Strategies for the discovery and development of therapies for metastatic breast cancer
Q37620640Suppression of tumor angiogenesis by targeting the protein neddylation pathway
Q39506220Survivin promotes glioma angiogenesis through vascular endothelial growth factor and basic fibroblast growth factor in vitro and in vivo.
Q33421361Switch maintenance treatment with oral vinorelbine and bevacizumab after induction chemotherapy with cisplatin, gemcitabine and bevacizumab in patients with advanced non-squamous non-small cell lung cancer: a phase II study
Q35783198Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity
Q33392869Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues
Q64100389Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment
Q28477256Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole
Q39800101Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines
Q47860855Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.
Q38062459Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer
Q33526062TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.
Q35787916TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types
Q38074430Targeted approach to metastatic colorectal cancer: what comes beyond epidermal growth factor receptor antibodies and bevacizumab?
Q28082828Targeted immune therapy of ovarian cancer
Q34040956Targeted inhibition of VEGF receptor 2: an update on ramucirumab
Q34878868Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action
Q34088696Targeted therapies in renal cell cancer: recent developments in imaging
Q37341824Targeted therapy in gastric cancer.
Q47640411Targeted therapy with apatinib in a patient with relapsed small cell lung cancer: A case report and literature review
Q92446657Targeting Angiogenesis in Prostate Cancer
Q38633308Targeting HER 2 and angiogenesis in gastric cancer
Q38964908Targeting Neovasculature with Multitargeted Antiangiogenesis Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer.
Q38799268Targeting acid sphingomyelinase with anti-angiogenic chemotherapy
Q38053680Targeting angiogenesis as a promising modality for the treatment of prostate cancer
Q89953634Targeting angiogenesis in gastrointestinal tumors: current challenges
Q38389997Targeting angiogenesis in lung cancer - Pitfalls in drug development
Q51732175Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin® protein MP0250: a preclinical study.
Q37563976Targeting angiogenesis: progress with anti-VEGF treatment with large molecules
Q29547395Targeting cancer with small molecule kinase inhibitors
Q34393461Targeting the PDGF signaling pathway in tumor treatment
Q34200930Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.
Q36626921Targeting the tumour microenvironment in ovarian cancer
Q37767356Targeting the tumour vasculature: insights from physiological angiogenesis
Q37359115Targeting tumor angiogenesis with histone deacetylase inhibitors
Q38118388Targeting tyrosine-kinases in ovarian cancer
Q28743072Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism
Q58112882Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling pathway
Q46407140Ten years of anti-vascular endothelial growth factor therapy
Q42831001Testin is a tumor suppressor and prognostic marker in breast cancer
Q33387704The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer
Q51745752The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis.
Q46358843The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer
Q38679301The Microenvironment of Lung Cancer and Therapeutic Implications
Q89724959The Multifaceted Roles of CXCL9 Within the Tumor Microenvironment
Q52719266The Platelet Lifeline to Cancer: Challenges and Opportunities.
Q59793680The Prognostic Value of the Combination of Low VEGFR-1 and High VEGFR-2 Expression in Endothelial Cells of Colorectal Cancer
Q50932310The Role of Angiogenesis in Cancer Treatment.
Q35654391The Vital Role of Blood Flow-Induced Proliferation and Migration in Capillary Network Formation in a Multiscale Model of Angiogenesis
Q45230734The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials
Q37725449The antiangiogenic role of the pro-inflammatory cytokine interleukin-31.
Q35626139The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells
Q37206338The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis
Q36827736The assessment of the prognostic value of tumor markers and cytokines as SCCAg, CYFRA 21.1, IL-6, VEGF and sTNF receptors in patients with squamous cell cervical cancer, particularly with early stage of the disease.
Q37987661The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities
Q34312566The characteristics of bone marrow-derived endothelial progenitor cells and their effect on glioma
Q93266252The combination of apatinib and S-1 for the treatment of advanced gastric cancer in China: A meta-analysis of randomized controlled trials
Q34669361The complexities of obesity and diabetes with the development and progression of pancreatic cancer
Q42434225The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells
Q37374031The definition of EPCs and other bone marrow cells contributing to neoangiogenesis and tumor growth: is there common ground for understanding the roles of numerous marrow-derived cells in the neoangiogenic process?
Q61803634The effect of cycling hypoxia on MCF-7 cancer stem cells and the impact of their microenvironment on angiogenesis using human umbilical vein endothelial cells (HUVECs) as a model
Q59793761The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks
Q51533513The effects of a picosecond pulsed electric field on angiogenesis in the cervical cancer xenograft models.
Q55083555The efficacy and safety of paclitaxel and carboplatin with versus without bevacizumab in patients with non-small-cell lung cancer: a systematic review and meta-analysis.
Q92568034The endothelial tip-stalk cell selection and shuffling during angiogenesis
Q33559661The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development
Q55002211The heterogenic tumor microenvironment of hepatocellular carcinoma and prognostic analysis based on tumor neo-vessels, macrophages and α-SMA.
Q37613407The immune system in the pathogenesis of ovarian cancer
Q26824086The impact of Bevacizumab (Avastin) on survival in metastatic solid tumors--a meta-analysis and systematic review
Q34988362The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer
Q38028791The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies
Q44603401The mRNA expression of various angiogenesis-related genes in pediatric sarcomas and nonmalignant lesions of tissue
Q38243969The miRNA network: micro-regulator of cell signaling in cancer
Q37821229The molecular biology of head and neck cancer
Q44622914The multitasking role of macrophages in Stanford type A acute aortic dissection.
Q28387803The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
Q38603771The potential of cell sheet technique on the development of hepatocellular carcinoma in rat models.
Q36630478The potential role of aerobic exercise to modulate cardiotoxicity of molecularly targeted cancer therapeutics.
Q90911537The pro-tumorigenic host response to cancer therapies
Q37088087The prothrombotic activity of cancer cells in the circulation
Q51791363The reduction in pigment epithelium-derived factor is a sign of malignancy in ovarian cancer expressing low-level of vascular endothelial growth factor.
Q37683553The role IL-1 in tumor-mediated angiogenesis
Q37486241The role of Notch and gamma-secretase inhibition in an ovarian cancer model
Q37833645The role of bevacizumab in colorectal cancer: understanding its benefits and limitations
Q45222224The role of bone marrow-derived cells during the bone healing process in the GFP mouse bone marrow transplantation model.
Q38099238The role of functional imaging in the era of targeted therapy of renal cell carcinoma
Q55019858The role of hypoxia in shaping the recruitment of proangiogenic and immunosuppressive cells in the tumor microenvironment.
Q39096266The role of mTOR inhibition as second-line therapy in metastatic renal carcinoma: clinical evidence and current challenges
Q38205134The role of targeted therapies in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline
Q39337947The safety and efficacy of ramucirumab in combination with docetaxel in the treatment of lung cancer
Q34612059The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma
Q39378690The single nucleotide polymorphism +936 C/T VEGF is associated with human epidermal growth factor receptor 2 expression in Moroccan breast cancer women
Q33559711The therapeutic promise of the cancer stem cell concept
Q39500842The toxicity of intrathecal bevacizumab in a rabbit model of leptomeningeal carcinomatosis
Q37318832The tumor microenvironment and its contribution to tumor evolution toward metastasis
Q34343645The tumor microenvironment in colorectal carcinogenesis
Q52935906The utility of cardiac biomarkers and echocardiography for the early detection of bevacizumab- and sunitinib-mediated cardiotoxicity.
Q35618768Therapeutic Angiogenesis by Gene Therapy for Critical Limb Ischemia: Choice of Biological Agent
Q38805228Therapeutic angiogenesis using tumor cell-conditioned medium.
Q47553195Therapeutic efficacy of a synthetic epsin mimetic peptide in glioma tumor model: uncovering multiple mechanisms beyond the VEGF-associated tumor angiogenesis
Q97692561Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors
Q28253120Therapeutic vulnerability of an in vivo model of alveolar soft part sarcoma (ASPS) to antiangiogenic therapy
Q47134647Therapy for Cancer: Strategy of Combining Anti-Angiogenic and Target Therapies
Q33862570Three-dimensional characterization of the vascular bed in bone metastasis of the rat by microcomputed tomography (MicroCT).
Q33810438Three-dimensional micro-MRI analysis of cerebral artery development in mouse embryos
Q30588927Three-dimensional reconstruction of neovasculature in solid tumors and basement membrane matrix using ex vivo X-ray microcomputed tomography
Q36113958Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1).
Q39540184Thrombospondin-1 expression in melanoma is blocked by methylation and targeted reversal by 5-Aza-deoxycytidine suppresses angiogenesis
Q33887928Tissue-engineered three-dimensional tumor models to study tumor angiogenesis.
Q37908815Towards tailored therapy of glioblastoma multiforme
Q34612724Tracking dynamic microvascular changes during healing after complete biopsy punch on the mouse pinna using optical microangiography.
Q38858806Translational aspects in targeting the stromal tumour microenvironment: from bench to bedside.
Q30499092Transplanting normal vascular proangiogenic cells to tumor-bearing mice triggers vascular remodeling and reduces hypoxia in tumors
Q36953476Treatment of pediatric brain tumors
Q37574433Treatment of retinal diseases with VEGF antagonists
Q49283018Treatment outcome of anti-angiogenesis through VEGF-pathway in the management of gastric cancer: a systematic review of phase II and III clinical trials
Q28482576Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts
Q37578166Tumor and host-mediated pathways of resistance and disease progression in response to antiangiogenic therapy.
Q36428702Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited
Q36535215Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs.
Q90478015Tumor endothelial marker 8 promotes cancer progression and metastasis
Q39912324Tumor metabolism: cancer cells give and take lactate
Q38057420Tumor vasculature: the Achilles' heel of cancer?
Q36499639Tumor vessel-injuring ability improves antitumor effect of cytotoxic T lymphocytes in adoptive immunotherapy
Q91386068Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma
Q37416806Tumoral angiogenesis and breast cancer
Q34497992Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide
Q38199737Type III or allosteric kinase inhibitors for the treatment of non-small cell lung cancer
Q38205041Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.
Q38066182Update and developments in the treatment of glioblastoma multiforme - focus on bevacizumab.
Q34348270Update on antiangiogenic therapy in colorectal cancer: aflibercept and regorafenib
Q39570902Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma
Q37947558Ups and downs of guided vessel sprouting: the role of polarity
Q35691033Use of S-100B to evaluate therapy effects during bevacizumab induction treatment in AJCC stage III melanoma
Q55194696VEGF +936 C/T Genetic Polymorphism in Patients with Cervical Dysplasia.
Q37951859VEGF gene alternative splicing: pro- and anti-angiogenic isoforms in cancer.
Q92229613VEGF in Signaling and Disease: Beyond Discovery and Development
Q33573974VEGF inhibition and metastasis: possible implications for antiangiogenic therapy
Q37264085VEGF inhibitors and prostate cancer therapy
Q36216197VEGF neutralizing aerosol therapy in primary pulmonary adenocarcinoma with K-ras activating-mutations
Q26770678VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside
Q34420871VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
Q37035757VEGF-A splicing: the key to anti-angiogenic therapeutics?
Q38982626VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes
Q41900132VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
Q38232368VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs
Q46202577VEGFR-1 expression levels predict occurrence of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma
Q54118788Validation of [18F]FLT as a perfusion-independent imaging biomarker of tumour response in EGFR-mutated NSCLC patients undergoing treatment with an EGFR tyrosine kinase inhibitor.
Q38236623Vandetanib as a potential treatment for breast cancer.
Q38821641Vascular Endothelial Growth Factor A Regulates the Secretion of Different Angiogenic Factors in Lung Cancer Cells
Q39691814Vascular Mimicry: The Next Big Glioblastoma Target
Q36286704Vascular endothelial growth factor D expression is a potential biomarker of bevacizumab benefit in colorectal cancer
Q35227644Vascular endothelial growth factor in anterior chamber liquid patients with diabetic retinopathy, cataract and neovascular glaucoma
Q37785877Vascular endothelial growth factor inhibitors in malignant gliomas.
Q54012562Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain.
Q37695468Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care
Q38266022Vascular endothelial growth factor trap-eye and trap technology: Aflibercept from bench to bedside
Q37117805Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth
Q41096029Vascular mimicry in glioblastoma following anti-angiogenic and anti-20-HETE therapies.
Q42750671Vascular phenotypes in primary non-small cell lung carcinomas and matched brain metastases
Q37407384Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
Q92059895Virus-Like Particles Presenting the FGF-2 Protein or Identified Antigenic Peptides Promoted Antitumor Immune Responses in Mice
Q44699541Walker 256/B malignant breast cancer cells improve femur angioarchitecture and disrupt hematological parameters in a rat model of tumor osteolysis
Q92267228Whole-lesion ADC histogram analysis is not able to reflect microvessel density in HNSCC
Q38410647Why some tumours trigger neovascularisation and others don't: the story thus far.
Q37840101XL184 (cabozantinib) for medullary thyroid carcinoma.
Q34658579Ziv-aflibercept in metastatic colorectal cancer
Q38152887Ziv-aflibercept: a novel angiogenesis inhibitor for the treatment of metastatic colorectal cancer
Q54566371[The study of PI3K/AKT pathway in lung cancer metastasis and drug resistance].
Q39056231hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer
Q33910328microRNAs and lung cancer: tumors and 22-mers.
Q37468744p53 Mutation: Critical Mediator of Therapy Resistance against Tumor Microenvironment
Q37241367αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target
Q36848635β -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells
Q35604861γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.

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