| P682 | biological process | epithelial to mesenchymal transition | Q74419 |
| regulation of gene expression | Q411391 | ||
| angiogenesis | Q539568 | ||
| Notch signaling pathway | Q904082 | ||
| negative regulation of transcription, DNA-templated | Q14633919 | ||
| transcription, DNA-templated | Q14763010 | ||
| positive regulation of transcription by RNA polymerase II | Q14818068 | ||
| regulation of cell population proliferation | Q14818120 | ||
| hair follicle maturation | Q14908094 | ||
| positive regulation of Notch signaling pathway | Q14912017 | ||
| endocardium morphogenesis | Q14912179 | ||
| ventricular trabecula myocardium morphogenesis | Q14914182 | ||
| regulation of timing of cell differentiation | Q14916210 | ||
| labyrinthine layer blood vessel development | Q15317715 | ||
| heart development | Q14819288 | ||
| defense response to bacterium | Q14820938 | ||
| regulation of transcription by RNA polymerase II | Q14852032 | ||
| blood vessel remodeling | Q14859590 | ||
| negative regulation of cell differentiation | Q14859959 | ||
| cell fate commitment | Q14860192 | ||
| negative regulation of ossification | Q14860506 | ||
| transcription initiation from RNA polymerase II promoter | Q14860785 | ||
| DNA recombination | Q14862222 | ||
| humoral immune response | Q14863386 | ||
| B cell differentiation | Q14863499 | ||
| keratinocyte differentiation | Q14864187 | ||
| somatic stem cell population maintenance | Q14864652 | ||
| positive regulation of cardiac muscle cell proliferation | Q14865337 | ||
| myeloid dendritic cell differentiation | Q14865490 | ||
| pituitary gland development | Q14886419 | ||
| artery morphogenesis | Q14890445 | ||
| neuron differentiation | Q14897720 | ||
| secondary heart field specification | Q14903261 | ||
| positive regulation of BMP signaling pathway | Q14903312 | ||
| positive regulation of cell proliferation involved in heart morphogenesis | Q14903591 | ||
| epithelial to mesenchymal transition involved in endocardial cushion formation | Q14904138 | ||
| atrioventricular canal development | Q14904145 | ||
| sebaceous gland development | Q14904147 | ||
| ventricular septum morphogenesis | Q14904373 | ||
| outflow tract morphogenesis | Q14906347 | ||
| inflammatory response to antigenic stimulus | Q14907247 | ||
| cardiac left ventricle morphogenesis | Q14908053 | ||
| hemopoiesis | Q919283 | ||
| somitogenesis | Q3489847 | ||
| negative regulation of cell population proliferation | Q14599399 | ||
| negative regulation of transcription by RNA polymerase II | Q14633878 | ||
| regulation of transcription, DNA-templated | Q14633883 | ||
| positive regulation of cell population proliferation | Q14633891 | ||
| positive regulation of gene expression | Q14633893 | ||
| Notch signaling involved in heart development | Q21096359 | ||
| positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | Q21097286 | ||
| club cell differentiation | Q21101545 | ||
| auditory receptor cell fate commitment | Q21101609 | ||
| dorsal aorta morphogenesis | Q21115825 | ||
| blood vessel lumenization | Q21115826 | ||
| endocardium development | Q21116511 | ||
| positive regulation of transcription of Notch receptor target | Q21119391 | ||
| epidermal cell fate specification | Q21132124 | ||
| positive regulation of ephrin receptor signaling pathway | Q21132125 | ||
| arterial endothelial cell fate commitment | Q21132126 | ||
| blood vessel endothelial cell fate specification | Q21132127 | ||
| positive regulation of ERBB signaling pathway | Q21132128 | ||
| positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | Q21132129 | ||
| aortic valve development | Q22298385 | ||
| pulmonary valve development | Q22298386 | ||
| negative regulation of cold-induced thermogenesis | Q54810623 | ||
| P681 | cell component | nucleolus | Q30869 |
| cytoplasm | Q79899 | ||
| nucleus | Q40260 | ||
| nucleoplasm | Q14817956 | ||
| transcription regulator complex | Q14818102 | ||
| MAML1-RBP-Jkappa- ICN1 complex | Q15334949 | ||
| transcription repressor complex | Q14864663 | ||
| P702 | encoded by | RBPJ | Q18027737 |
| P703 | found in taxon | Homo sapiens | Q15978631 |
| P680 | molecular function | protein binding | Q167149 |
| DNA-binding transcription activator activity, RNA polymerase II-specific | Q14817973 | ||
| chromatin binding | Q14817976 | ||
| DNA-binding transcription factor activity | Q14817979 | ||
| transcription factor binding | Q14817982 | ||
| protein N-terminus binding | Q14817992 | ||
| sequence-specific DNA binding | Q14818107 | ||
| DNA-binding transcription factor activity, RNA polymerase II-specific | Q14864645 | ||
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | Q14864824 | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Q14885806 | ||
| DNA binding | Q14633858 | ||
| DNA strand exchange activity | Q21095317 |
| Q50257904 | CSL NICD coactivator complex [nucleoplasm] |
| Q113151340 | CSL-NOTCH1-MAML transcriptional activation complex |
| Q100153972 | Formation of CSL NCOR corepressor complex |
| Q50290085 | Formation of CSL-NICD coactivator complex |
| Q50256027 | NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] |
| Q50258526 | NICD1:RBPJ:SNW1 [nucleoplasm] |
| Q50298670 | NICD2 binds RBPJ and MAML in the nucleus |
| Q55219512 | NICD3 binds RBPJ and MAML in the nucleus |
| Q56860730 | NICD4 binds RBPJ and MAML in the nucleus |
| Q50273360 | NOTCH2 Coactivator Complex [nucleoplasm] |
| Q50273171 | NOTCH3 coactivator complex [nucleoplasm] |
| Q56856839 | NOTCH4 coactivator complex [nucleoplasm] |
| Q50287840 | RBPJ- and NOTCH1-dependent synthesis of HES1 protein during morphogenesis |
| Q50256021 | RBPJ:NCOR corepressor complex [nucleoplasm] |
| Q50256043 | RBPJ:SNW1 [nucleoplasm] |
| Q28910481 | A metabolic enzyme of the short-chain dehydrogenase/reductase superfamily may moonlight in the nucleus as a repressor of promoter activity |
| Q22008610 | CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex |
| Q24292921 | Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis |
| Q34275062 | Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity |
| Q24301606 | Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. |
| Q24307974 | Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2 |
| Q24294890 | RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes |
| Q24308025 | RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J. |
| Q22253329 | SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function |
| Q24306223 | The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis |
| Q18027737 | RBPJ | encodes | P688 |
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