MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

scientific article

MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1146/ANNUREV.BIOCHEM.67.1.99
P3181OpenCitations bibliographic resource ID4319980
P698PubMed publication ID9759484
P5875ResearchGate publication ID13525536

P50authorFritz EcksteinQ1466082
P2093author name stringSandeep Verma
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages36
P304page(s)99-134
P577publication date1998-06-01
P1433published inAnnual Review of BiochemistryQ567356
P1476titleMODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users
P478volume67

Reverse relations

cites work (P2860)
Q851949382′-Amino-Modified Ribonucleotides as Probes for Local Interactions Within RNA
Q419549545'-deoxy-5'-hydrazinylguanosine as an initiator of T7 Rna polymerase-catalyzed transcriptions for the preparation of labeling-ready RNAs.
Q41121184A Novel and Intuitive Method of Displaying and Interacting with Mass Difference Information: Application to Oligonucleotide Drug Impurities
Q38165645A brief review of methods for terminal functionalization of DNA.
Q42649730A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions.
Q38319775A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA.
Q47417991A new DNA analogue with expanded size and scope
Q41912492A short fragment of 23S rRNA containing the binding sites for two ribosomal proteins, L24 and L4, is a key element for rRNA folding during early assembly
Q42917512Alteration of cross-linking selectivity with the 2′-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects
Q30960956Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides
Q31988388Chemical synthesis and biological investigation of a 77-mer oligoribonucleotide with a sequence corresponding to E. coli tRNA(Asp).
Q38288505Communications between catalytic sites in the protein-DNA synapse by the SfiI endonuclease
Q37850774Controlling forces and pathways in self-assembly using viruses and DNA.
Q28117100Coordination of divalent metal ions in the active site of poly(A)-specific ribonuclease
Q35007006Crystallization and preliminary X-ray analysis of the type IV restriction endonuclease ScoMcrA from Streptomyces coelicolor, which cleaves both Dcm-methylated DNA and phosphorothioated DNA
Q36069661DNA-multichromophore systems
Q41946566Delta ribozyme benefits from a good stability in vitro that becomes outstanding in vivo
Q45713923Design and application of an easy to use oligonucleotide mass calculation program
Q27007011Design and application of multifunctional DNA nanocarriers for therapeutic delivery
Q50509310Design, assembly, and activity of antisense DNA nanostructures.
Q41957085Determination of 2'-hydroxyl and phosphate groups important for aminoacylation of Escherichia coli tRNAAsp: a nucleotide analogue interference study
Q35012309Developments in RNA chemistry, a personal view
Q33911877Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P
Q34835124Effective inhibition of Rta expression and lytic replication of Kaposi's sarcoma-associated herpesvirus by human RNase P.
Q35212574Engineering of RNase P ribozyme for gene-targeting applications
Q37967636Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers
Q26740493Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes
Q33762078Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures
Q33846993Fluorescent analogs of biomolecular building blocks: design, properties, and applications
Q46237618Fluorescent nucleobases as tools for studying DNA and RNA.
Q35054594Functional tuning of nucleic acids by chemical modifications: tailored oligonucleotides as drugs, devices, and diagnostics
Q36921638Gene modulation for treating liver fibrosis
Q44905168Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution
Q39939619Hoogsteen-paired homopurine [RP-PS]-DNA and homopyrimidine RNA strands form a thermally stable parallel duplex
Q40778337Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites
Q41906010Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA.
Q24796916Improving signal intensities for genes with low-expression on oligonucleotide microarrays
Q35890651In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex
Q40883283In vitro selection of novel RNA ligands that bind human cytomegalovirus and block viral infection
Q36988728Inhibition of gene expression in human cells using RNase P-derived ribozymes and external guide sequences
Q53845653Inhibition of non-homologous end joining and integration of DNA upon transformation of Rhizopus oryzae.
Q27662385Insights into the DNA stabilizing contributions of a bicyclic cytosine analogue: crystal structures of DNA duplexes containing 7,8-dihydropyrido [2,3-d]pyrimidin-2-one
Q45888150Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop
Q63761348Intercalating Nucleic Acids with Insertion of 5-[(Pyren-1-yl)methylidene]hydantoin-Substituted Butane-1,2-diol
Q74251949Interstrand disulfide cross-linking of internal sugar residues in duplex RNA
Q42144869Kinetic and binding analysis of the catalytic involvement of ribose moieties of a trans-acting delta ribozyme
Q36848309Long-range distance determinations in biomacromolecules by EPR spectroscopy
Q30791792Matching organic libraries with protein-substructures.
Q42169091Microwave-assisted functionalization of solid supports for rapid loading of nucleosides
Q43033805Modified DNA bearing 5(methoxycarbonylmethyl)-2'-deoxyuridine: preparation by PCR with thermophilic DNA polymerase and postsynthetic derivatization
Q36316652Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA.
Q58127513New Trends in Nucleic Acids Based Biosensors—Florence, Italy, October 25–28, 2003
Q53814644Nuclease stability of boron-modified nucleic acids: application to label-free mismatch detection.
Q27657724Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
Q37920738Nucleic acid amphiphiles: synthesis and self-assembled nanostructures
Q50101001Oligonucleotide modifications enhance probe stability for single cell transcriptome in vivo analysis (TIVA).
Q38618638Oligonucleotide therapeutics: chemistry, delivery and clinical progress
Q44061365Oligonucleotides containing 7-vinyl-7-deazaguanine as a facile strategy for expanding the functional diversity of DNA.
Q33761599On the observation of discrete fluorine NMR spectra for uridine 5'-β,γ-fluoromethylenetriphosphate diastereomers at basic pH.
Q47761182Optimization and generality of a small deoxyribozyme that ligates RNA.
Q33928709Phosphorothioate modification of RNA for stereochemical and interference analyses
Q81464956Phosphorothioation of DNA in bacteria
Q39542570Polymorphisms in the large subunit of human RNA polymerase II as target for allele-specific inhibition
Q45986577Preparation of short interfering RNA containing the modified nucleosides 2-thiouridine, pseudouridine, or dihydrouridine.
Q28730631Prolonged fasting increases purine recycling in post-weaned northern elephant seals
Q57126282Prototropic tautomerism and basic molecular principles of hypoxanthine mutagenicity: an exhaustive quantum-chemical analysis
Q53188225Quality control of oligonucleotide synthesis by means of matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry on a nanocoated disposable target.
Q34522185RAPID FUNCTIONALIZATION AND LOADING OF SOLID SUPPORTS
Q36407791RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon
Q38295867Regulation of fibrin-mediated tumor cell adhesion to the endothelium using anti-thrombin aptamer
Q35567989Ribonucleic acid (RNA) biosynthesis in human cancer
Q35687704Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: application of a method called SERF
Q24537549Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
Q31128364Single base extension (SBE) with proofreading polymerases and phosphorothioate primers: improved fidelity in single-substrate assays
Q97892789Solid-Phase Synthesis of RNA 5'-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry
Q47786647Solid-Phase Synthesis of RNA Analogs Containing Phosphorodithioate Linkages
Q43741779Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages
Q37896490Stereocontrolled synthesis of oligonucleotide analogs containing chiral internucleotidic phosphorus atoms.
Q92757172Structural and Functional Stability of DNA Nanopores in Biological Media
Q34285001Survey and summary: The applications of universal DNA base analogues
Q43741645Synthesis and properties of novel triphosphate analogues: ribonucleoside and deoxyribonucleoside (alpha-P-borano, alpha-P-thio)triphosphates
Q57895656Synthesis of 3-(2-deoxy-β-d-ribofuranosyl)pyridin-2-one and 2-amino-6-(N,N-dimethylamino)-9-(2-deoxy-β-d-ribofuranosyl)purine derivatives for an unnatural base pair
Q92732764Synthesis of Oligonucleotides Containing 2'-N-alkylaminocarbonyl-2'-amino-LNA (2'-urea-LNA) Moieties Using Post-Synthetic Modification Strategy
Q34517805Synthesis of new classes of boron-containing nucleotides
Q40695358Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage
Q49958662Systematic optimization and modification of a DNA aptamer with 2'-O-methyl RNA analogues.
Q41914615The use of nano-sized acicular material, sliding friction, and antisense DNA oligonucleotides to silence bacterial genes
Q38228101Therapeutic targeting of microRNAs: current status and future challenges
Q28833703Twenty years hunting for sulfur in DNA
Q35856552Unnatural base pairs for specific transcription
Q42183632Unusual thermal stability of RNA/[RP-PS]-DNA/RNA triplexes containing a homopurine DNA strand
Q37546163Using modified aptamers for site specific protein-aptamer conjugations
Q92799447Utilization of G-Quadruplex-Forming Aptamers for the Construction of Luminescence Sensing Platforms
Q27472971Zeptomole detection of a viral nucleic acid using a target-activated ribozyme

Search more.