topiramate

an anticonvulsant (antiepilepsy) drug

Wikidata entity: Q221174

C₁₂H₂₁NO₈S (P274)


Wikimedia Commons category is Topiramate



Quantities

P4250defined daily dose0.3
P2067mass339.099

P3780 active ingredient in ... Q47522053 (Qudexy) Qudexy
P3780 active ingredient in ... Q47522216 (Topamax) Topamax
P3780 active ingredient in ... Q47522236 (Trokendi) Trokendi
P3780 active ingredient in ... Q48829128 (Topiragen) Topiragen
P233 canonical SMILES String CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C ???
P373 Commons category String Topiramate ???
P1552 has characteristic ... Q1517187 (bitterness) bitterness
P366 has use ... Q12140 (medication) medication
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P2017 isomeric SMILES String CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C ???
P3493 legal status (medicine) ... Q879952 (boxed warning) boxed warning
P2175 medical condition treated ... Q41571 (epilepsy) epilepsy
P2175 medical condition treated ... Q81938 (pain) pain
P2175 medical condition treated ... Q131755 (bipolar disorder) bipolar disorder
P2175 medical condition treated ... Q202387 (post-traumatic stress disorder) post-traumatic stress disorder
P2175 medical condition treated ... Q188638 (mood disorder) mood disorder
P2175 medical condition treated ... Q133823 (migraine) migraine
P2175 medical condition treated ... Q693519 (essential tremor) essential tremor
P2175 medical condition treated ... Q1406803 (tonic–clonic seizure) tonic–clonic seizure
P2175 medical condition treated ... Q7140388 (focal epilepsy) focal epilepsy
P2175 medical condition treated ... Q18553762 (migraine with aura) migraine with aura
P2175 medical condition treated ... Q18555095 (infantile epileptic encephalopathy) infantile epileptic encephalopathy
P2175 medical condition treated ... Q18558125 (intracranial hypertension) intracranial hypertension
P129 physically interacts with ... Q1486720 (Glutamate ionotropic receptor AMPA type subunit 3) Glutamate ionotropic receptor AMPA type subunit 3
P129 physically interacts with ... Q3459294 (Sodium voltage-gated channel alpha subunit 5) Sodium voltage-gated channel alpha subunit 5
P129 physically interacts with ... Q5038044 (Carbonic anhydrase 4) Carbonic anhydrase 4
P129 physically interacts with ... Q5512777 (Gamma-aminobutyric acid type A receptor subunit alpha4) Gamma-aminobutyric acid type A receptor subunit alpha4
P129 physically interacts with ... Q6981557 (Sodium voltage-gated channel alpha subunit 4) Sodium voltage-gated channel alpha subunit 4
P129 physically interacts with ... Q6981560 (Sodium voltage-gated channel alpha subunit 9) Sodium voltage-gated channel alpha subunit 9
P129 physically interacts with ... Q6981561 (Sodium voltage-gated channel alpha subunit 11) Sodium voltage-gated channel alpha subunit 11
P129 physically interacts with ... Q21108701 (Glutamate ionotropic receptor kainate type subunit 1) Glutamate ionotropic receptor kainate type subunit 1
P129 physically interacts with ... Q21108705 (Glutamate ionotropic receptor kainate type subunit 3) Glutamate ionotropic receptor kainate type subunit 3
P129 physically interacts with ... Q21108706 (Glutamate ionotropic receptor kainate type subunit 4) Glutamate ionotropic receptor kainate type subunit 4
P129 physically interacts with ... Q21113297 (Gamma-aminobutyric acid type A receptor subunit delta) Gamma-aminobutyric acid type A receptor subunit delta
P129 physically interacts with ... Q21113305 (Gamma-aminobutyric acid type A receptor subunit gamma2) Gamma-aminobutyric acid type A receptor subunit gamma2
P129 physically interacts with ... Q21113312 (Gamma-aminobutyric acid type A receptor subunit beta3) Gamma-aminobutyric acid type A receptor subunit beta3
P129 physically interacts with ... Q21113314 (Gamma-aminobutyric acid type A receptor subunit beta2) Gamma-aminobutyric acid type A receptor subunit beta2
P129 physically interacts with ... Q21113326 (Gamma-aminobutyric acid type A receptor subunit gamma1) Gamma-aminobutyric acid type A receptor subunit gamma1
P129 physically interacts with ... Q21113337 (Gamma-aminobutyric acid type A receptor subunit theta) Gamma-aminobutyric acid type A receptor subunit theta
P129 physically interacts with ... Q21113344 (Glutamate ionotropic receptor kainate type subunit 2) Glutamate ionotropic receptor kainate type subunit 2
P129 physically interacts with ... Q21113351 (Glutamate ionotropic receptor kainate type subunit 5) Glutamate ionotropic receptor kainate type subunit 5
P129 physically interacts with ... Q21114574 (Gamma-aminobutyric acid type A receptor subunit beta1) Gamma-aminobutyric acid type A receptor subunit beta1
P129 physically interacts with ... Q21114578 (Gamma-aminobutyric acid type A receptor subunit alpha3) Gamma-aminobutyric acid type A receptor subunit alpha3
P129 physically interacts with ... Q21115961 (Glutamate ionotropic receptor AMPA type subunit 1) Glutamate ionotropic receptor AMPA type subunit 1
P129 physically interacts with ... Q21116946 (Carbonic anhydrase 12) Carbonic anhydrase 12
P129 physically interacts with ... Q21126314 (sodium voltage-gated channel alpha subunit 1) sodium voltage-gated channel alpha subunit 1
P129 physically interacts with ... Q21126334 (Sodium voltage-gated channel alpha subunit 10) Sodium voltage-gated channel alpha subunit 10
P129 physically interacts with ... Q21132911 (Carbonic anhydrase 2) Carbonic anhydrase 2
P129 physically interacts with ... Q21132915 (Carbonic anhydrase 7) Carbonic anhydrase 7
P129 physically interacts with ... Q21135448 (Sodium voltage-gated channel alpha subunit 2) Sodium voltage-gated channel alpha subunit 2
P129 physically interacts with ... Q21135449 (Sodium voltage-gated channel alpha subunit 3) Sodium voltage-gated channel alpha subunit 3
P129 physically interacts with ... Q21173164 (Carbonic anhydrase 1) Carbonic anhydrase 1
P3489 pregnancy category ... Q3679274 (Australian pregnancy category D) Australian pregnancy category D
P3489 pregnancy category ... Q28123618 (US pregnancy category D) US pregnancy category D
P279 subclass of ... Q126615356 (2,2,7,7-tetramethyltetrahydro-2H,3aH,7H-bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran-3a-yl)methyl sulfamate) 2,2,7,7-tetramethyltetrahydro-2H,3aH,7H-bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran-3a-yl)methyl sulfamate
P2868 subject has role ... Q414238 (carbonic anhydrase inhibitor) carbonic anhydrase inhibitor
P2868 subject has role ... Q576618 (anticonvulsant agent) anticonvulsant agent
P2868 subject has role ... Q1303753 (anti-obesity medication) anti-obesity medication
P2868 subject has role ... Q50377190 (neuroprotective agent) neuroprotective agent
P2868 subject has role ... Q72941151 (developmental toxicant) developmental toxicant
P2275 World Health Organisation international non-proprietary name Monolingualtext topiramate ???

External Ids
P267ATC codeN03AX11
P7524CA PROP 65 IDtopiramate
P231CAS Registry Number97240-79-4
P683ChEBI ID63631
P592ChEMBL IDCHEMBL220492
P661ChemSpider ID4447672
P3073CosIng number90620
P9272DeCS ID57558
P715DrugBank IDDB00273
P11198DrugCentral ID2706
P8494DSSTOX compound identifierDTXCID103688
P3117DSSTox substance IDDTXSID8023688
P232EC number619-263-3
P2566ECHA Substance Infocard ID100.129.713
P1417Encyclopædia Britannica Online IDtopic/topiramate
P646Freebase ID/m/01qb88
P595Guide to Pharmacology Ligand ID6849
P2062HSDB ID7531
P2057Human Metabolome Database IDHMDB0005034
P234InChIInChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1
P235InChIKeyKJADKKWYZYXHBB-XBWDGYHZSA-N
P665KEGG IDD00537
P244Library of Congress authority IDsh97000684
P6689MassBank accession IDMSBNK-Waters-WA001873
P6689MassBank accession IDMSBNK-Waters-WA001874
P6689MassBank accession IDMSBNK-Waters-WA001875
P6689MassBank accession IDMSBNK-Waters-WA001876
P6689MassBank accession IDMSBNK-Waters-WA001877
P10245MedlinePlus drug identifiera697012
P486MeSH descriptor IDD000077236
P672MeSH tree codeD09.947.875.359.250.500
P672MeSH tree codeD09.947.875.465.354.500
P6366Microsoft Academic ID (discontinued)2777683783
P8189National Library of Israel J9U ID987007551783705171
P2115NDF-RT IDN0000148493
P2840NSC number759251
P10283OpenAlex IDC2777683783
P4235PatientsLikeMe treatment IDtopiramate
P3636PDB ligand IDTOR
P638PDB structure ID3LXE
P638PDB structure ID3HKU
P11199Probes And Drugs IDPD000722
P662PubChem CID5284627
P3417Quora topic IDTopiramate
P1579Reaxys registry number5988957
P3345RxNorm CUI38404
P4964SPLASHsplash10-00di-0059000000-415c62c34b95b430780e
P4964SPLASHsplash10-014i-0090000000-114dcddef02a03a7e050
P4964SPLASHsplash10-01x0-1970000000-f0e80f5cc5d6fc2b6d38
P4964SPLASHsplash10-03di-0239000000-994a7b97e101c455a792
P2877SureChEMBL ID34631
P4527UK Parliament thesaurus ID510289
P2892UMLS CUIC0076829
P2892UMLS CUIC0127173
P11089UniChem compound ID128687
P652UNII0H73WJJ391
P11143WikiProjectMed IDTopiramate
P13591Yale LUX IDconcept/4726b6b8-efe7-4369-a816-b36e8ab09959

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