Sodium voltage-gated channel alpha subunit 2

mammalian protein found in Homo sapiens

Wikidata entity: Q21135448



P682 biological process ... Q492 (memory) memory
P682 biological process ... Q1345738 (nervous system development) nervous system development
P682 biological process ... Q14818077 (neuron apoptotic process) neuron apoptotic process
P682 biological process ... Q14818081 (cellular response to hypoxia) cellular response to hypoxia
P682 biological process ... Q14820680 (transmembrane transport) transmembrane transport
P682 biological process ... Q14859673 (ion transport) ion transport
P682 biological process ... Q14865155 (regulation of ion transmembrane transport) regulation of ion transmembrane transport
P682 biological process ... Q14876135 (myelination) myelination
P682 biological process ... Q14881098 (sodium ion transport) sodium ion transport
P682 biological process ... Q14904837 (sodium ion transmembrane transport) sodium ion transmembrane transport
P682 biological process ... Q14905722 (membrane depolarization during action potential) membrane depolarization during action potential
P682 biological process ... Q14907683 (neuronal action potential) neuronal action potential
P682 biological process ... Q21135447 (intrinsic apoptotic signaling pathway in response to osmotic stress) intrinsic apoptotic signaling pathway in response to osmotic stress
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q924483 (node of Ranvier) node of Ranvier
P681 cell component ... Q178999 (axon) axon
P681 cell component ... Q2983734 (T-tubule) T-tubule
P681 cell component ... Q3824358 (intracellular anatomical structure) intracellular anatomical structure
P681 cell component ... Q6045608 (intercalated disc) intercalated disc
P681 cell component ... Q14327652 (integral component of membrane) integral component of membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14859540 (integral component of plasma membrane) integral component of plasma membrane
P681 cell component ... Q14905705 (voltage-gated sodium channel complex) voltage-gated sodium channel complex
P681 cell component ... Q14905731 (sodium channel complex) sodium channel complex
P681 cell component ... Q14906302 (paranode region of axon) paranode region of axon
P681 cell component ... Q21095104 (intrinsic component of plasma membrane) intrinsic component of plasma membrane
P681 cell component ... Q24629101 (glutamatergic synapse) glutamatergic synapse
P681 cell component ... Q26253861 (integral component of presynaptic membrane) integral component of presynaptic membrane
P702 encoded by ... Q18031394 (SCN2A) SCN2A
P2888 exact match Url UniProt ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24767982 (Ion transport domain) Ion transport domain
P527 has part(s) ... Q24769066 (Sodium ion transport-associated) Sodium ion transport-associated
P527 has part(s) ... Q24773130 (Voltage-gated Na+ ion channel, cytoplasmic domain) Voltage-gated Na+ ion channel, cytoplasmic domain
P527 has part(s) ... Q24784373 (IQ motif, EF-hand binding site) IQ motif, EF-hand binding site
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q14864714 (ion channel activity) ion channel activity
P680 molecular function ... Q14865152 (voltage-gated ion channel activity) voltage-gated ion channel activity
P680 molecular function ... Q14905706 (voltage-gated sodium channel activity) voltage-gated sodium channel activity
P680 molecular function ... Q14905710 (sodium channel activity) sodium channel activity
P361 part of ... Q24771424 (Voltage gated sodium channel, alpha subunit) Voltage gated sodium channel, alpha subunit
P361 part of ... Q54444446 (Voltage-dependent channel domain superfamily) Voltage-dependent channel domain superfamily
P361 part of ... Q70444589 (Voltage gated sodium channel) Voltage gated sodium channel
P361 part of ... Q83138248 (Ion transport domain, protein family) Ion transport domain, protein family
P361 part of ... Q83138691 (Sodium ion transport-associated domain, protein family) Sodium ion transport-associated domain, protein family
P361 part of ... Q83140953 (Voltage-gated Na+ ion channel, cytoplasmic domain, protein family) Voltage-gated Na+ ion channel, cytoplasmic domain, protein family
P361 part of ... Q95351939 (IQ motif, EF-hand binding site, protein family) IQ motif, EF-hand binding site, protein family
P129 physically interacts with ... Q1175385 (mephenytoin) mephenytoin
P129 physically interacts with ... Q221174 (topiramate) topiramate
P129 physically interacts with ... Q410400 (phenytoin) phenytoin
P129 physically interacts with ... Q176301 (oxcarbazepine) oxcarbazepine
P129 physically interacts with ... Q1530958 (oxybuprocaine) oxybuprocaine
P129 physically interacts with ... Q209202 (dichlorobenzyl alcohol) dichlorobenzyl alcohol
P129 physically interacts with ... Q216935 (lidocaine) lidocaine
P129 physically interacts with ... Q219957 (zonisamide) zonisamide
P129 physically interacts with ... Q15051328 (indecainide) indecainide
P129 physically interacts with ... Q19597602 (Irampanel) Irampanel
P129 physically interacts with ... Q21098885 (priralfinamide) priralfinamide
P129 physically interacts with ... Q21098995 (Evenamide) Evenamide
P129 physically interacts with ... Q27068150 (chloroprocaine hydrochloride) chloroprocaine hydrochloride
P129 physically interacts with ... Q27077226 (eslicarbazepine) eslicarbazepine
P129 physically interacts with ... Q27094388 (quinidine gluconate) quinidine gluconate
P129 physically interacts with ... Q27106430 (disopyramide phosphate) disopyramide phosphate
P129 physically interacts with ... Q27106453 (dyclonine hydrochloride) dyclonine hydrochloride
P129 physically interacts with ... Q27107324 (mepivacaine hydrochloride) mepivacaine hydrochloride
P129 physically interacts with ... Q27107357 ((RS)-mexiletine hydrochloride) (RS)-mexiletine hydrochloride
P129 physically interacts with ... Q27107584 (orphenadrine citrate) orphenadrine citrate
P129 physically interacts with ... Q27108080 (procainamide hydrochloride) procainamide hydrochloride
P129 physically interacts with ... Q27108087 (propafenone hydrochloride) propafenone hydrochloride
P129 physically interacts with ... Q27114248 (benoxinate hydrochloride) benoxinate hydrochloride
P129 physically interacts with ... Q27114764 (prilocaine hydrochloride) prilocaine hydrochloride

External Ids
P705Ensembl protein IDENSP00000486885
P705Ensembl protein IDENSP00000489873
P705Ensembl protein IDENSP00000490800
P705Ensembl protein IDENSP00000490866
P705Ensembl protein IDENSP00000501305
P705Ensembl protein IDENSP00000364576
P705Ensembl protein IDENSP00000490107
P705Ensembl protein IDENSP00000489821
P705Ensembl protein IDENSP00000490765
P705Ensembl protein IDENSP00000501309
P705Ensembl protein IDENSP00000364586
P705Ensembl protein IDENSP00000490592
P705Ensembl protein IDENSP00000283256
P705Ensembl protein IDENSP00000406454
P705Ensembl protein IDENSP00000487466
P705Ensembl protein IDENSP00000500975
P705Ensembl protein IDENSP00000490849
P486MeSH descriptor IDD062551
P672MeSH tree codeD12.776.157.530.400.875.750.200
P672MeSH tree codeD12.776.543.550.450.875.750.200
P672MeSH tree codeD12.776.543.585.400.875.750.200
P672MeSH tree codeD12.776.631.960.200
P638PDB structure ID4JPZ
P638PDB structure ID2KAV
P637RefSeq protein IDNP_001035232
P637RefSeq protein IDNP_001035233
P637RefSeq protein IDNP_001358175
P637RefSeq protein IDNP_001358176
P637RefSeq protein IDNP_066287
P637RefSeq protein IDXP_016860145
P637RefSeq protein IDXP_016860146
P637RefSeq protein IDXP_016860147
P637RefSeq protein IDXP_016860148
P637RefSeq protein IDXP_024308805
P7260Transporter Classification Database ID1.A.1.10.12
P352UniProt protein IDQ99250

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