Statins and dementia

scientific article

Statins and dementia is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1016519716
P356DOI10.1007/S11883-007-0012-9
P3181OpenCitations bibliographic resource ID4235280
P698PubMed publication ID17877925

P50authorLewis KullerQ88077314
P2860cites workGene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset familiesQ27860677
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trialQ28214393
Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer diseaseQ28216782
Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulationQ28613091
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Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyondQ33702396
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Can statin therapy really reduce the risk of Alzheimer's disease and slow its progression?Q36308740
Cholesterol in Alzheimer's diseaseQ36317585
Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force.Q36438054
Epidemiological and clinical trials evidence about a preventive role for statins in Alzheimer's diseaseQ36546512
Interventions for heart disease and their effects on Alzheimer's diseaseQ36582781
From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humansQ43681969
Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brainQ43885523
Serum lipoprotein levels, statin use, and cognitive function in older womenQ43915654
Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptideQ44187794
Use of lipid-lowering drugs in older adults with and without dementia: a community-based epidemiological studyQ44201251
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers.Q44300030
APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: the Three-City Study.Q44657566
Statins and cognitive function in the elderly: the Cardiovascular Health StudyQ46794954
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterolQ48161830
Caloric intake and the risk of Alzheimer diseaseQ48520005
Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.Q48578997
Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort.Q51926808
Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study.Q51933375
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.Q52937381
Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study.Q53265427
Statin Use and the Risk of Incident DementiaQ57392350
Formation of oxysterols from different pools of cholesterol as studied by stable isotope technique: cerebral origin of most circulating 24S-hydroxycholesterol in rats, but not in miceQ59306993
Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control studyQ72319626
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patientsQ73462725
Statin therapy in the treatment of Alzheimer disease: what is the rationale?Q81631120
P433issue2
P921main subjectdementiaQ83030
P304page(s)154-161
P577publication date2007-04-01
P1433published inCurrent Atherosclerosis ReportsQ20821076
P1476titleStatins and dementia
P478volume9

Reverse relations

cites work (P2860)
Q37165703Current and future therapy in Alzheimer's disease.
Q37827489Current perspectives on pharmacotherapy of Alzheimer's disease
Q35394390Dementia and Alzheimer's disease: a new direction.The 2010 Jay L. Foster Memorial Lecture
Q38628959Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1.
Q34572020Frontiers in the pathogenesis of Alzheimer's disease
Q38819005Highly electronegative low-density lipoprotein L5 evokes microglial activation and creates a neuroinflammatory stress via Toll-like receptor 4 signaling.
Q41995769Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity
Q35947072Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease.
Q37198579Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?
Q36553735Risk of dementia and death in the long-term follow-up of the Pittsburgh Cardiovascular Health Study-Cognition Study
Q35843502Statins and brain integrity in older adults: secondary analysis of the Health ABC study
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Q37139026Towards onset prevention of cognition decline in adults with Down syndrome (The TOP-COG study): A pilot randomised controlled trial

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