Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3

scientific article

Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.74.11.5233-5241.2000
P932PMC publication ID110877
P698PubMed publication ID10799599

P2093author name stringB Hahm
S K Jang
J Lee
J Lim
S Cho
M Seedorf
J E Kim
K M Chung
O K Song
P2860cites workNuclear protein importQ34426767
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Analysis of genotypes and amino acid residues 2209 to 2248 of the NS5A region of hepatitis C virus in relation to the response to interferon-beta therapyQ42981569
Identification of the protease domain in NS3 of hepatitis C virusQ42981605
The amino terminal deletion mutants of hepatitis C virus nonstructural protein NS5A function as transcriptional activators in yeastQ42984045
Hepatitis C virus nonstructural protein 5A contains potential transcriptional activator domains.Q42985717
Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growthQ42993783
Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findingsQ42994660
Subcellular localization of hepatitis C viral proteins in mammalian cellsQ42995004
The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursorQ43048247
Inhibition of Ran guanosine triphosphatase-dependent nuclear transport by the matrix protein of vesicular stomatitis virusQ45762580
Decreased phorbol myristate acetate-induced release of tumor necrosis factor-alpha and interleukin-1 beta from peripheral blood monocytes of patients chronically infected with hepatitis C virusQ45767644
Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosisQ45844531
Karyopherins and kissing cousinsQ47721363
Transport routes through the nuclear pore complexQ47926615
Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiaeQ48183765
NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signalingQ22009551
Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like proteinQ22010735
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A proteinQ24319002
Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cellsQ24319791
Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1Q24336127
Kinetic and structural analyses of hepatitis C virus polyprotein processingQ24648164
Cloning and characterization of human karyopherin beta3Q24680128
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulationQ27469500
Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyproteinQ27469751
Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A regionQ27478292
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processingQ27478455
NS3-4A of hepatitis C virus is a chymotrypsin-like proteaseQ27478468
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5AQ27478481
The N-terminal region of hepatitis C virus-encoded NS5A is important for NS4A-dependent phosphorylationQ27480777
Hepatitis C virus nonstructural region 5A protein is a potent transcriptional activatorQ27480896
Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteinsQ27485988
Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kineticsQ27486009
Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sitesQ27486027
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctionsQ27486051
NS3 is a serine protease required for processing of hepatitis C virus polyproteinQ27486059
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virusQ27486062
Structure and organization of the hepatitis C virus genome isolated from human carriersQ27486168
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genomeQ27860719
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitisQ27860909
Importin/karyopherin protein family members required for mRNA export from the nucleusQ27934542
Improved method for high efficiency transformation of intact yeast cellsQ28131608
Hepatitis C virus infection is associated with the development of hepatocellular carcinomaQ28131791
Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitisQ29547897
Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virusQ29619471
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infectionQ29620702
A second hepatitis C virus-encoded proteinaseQ29620770
Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroupsQ29620772
C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activityQ29620775
Epstein-Barr virus BARF1 protein is dispensable for B-cell transformation and inhibits alpha interferon secretion from mononuclear cells.Q33650107
P433issue11
P407language of work or nameEnglishQ1860
P921main subjecthepatitis CQ154869
virologyQ7215
Hepatitis C virusQ708693
P304page(s)5233-5241
P577publication date2000-06-01
P1433published inJournal of VirologyQ1251128
P1476titleNonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3
P478volume74

Reverse relations

cites work (P2860)
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