Abstract is: Ida Stephens Owens (September 13, 1939 – February 24, 2020) was an American scientist known for her work with drug-detoxifying enzymes. She received her Ph.D from Duke University in 1967, making her one of the first two African Americans to receive a doctorate from the school. She spent her career at the National Institutes of Health (NIH), where she worked from 1968 to 2017 and pioneered the study of the genetics of human diseases and drug metabolism.
| human | Q5 |
| P2671 | Google Knowledge Graph ID | /g/11cmh55htk |
| P27 | country of citizenship | United States of America | Q30 |
| P69 | educated at | Duke University | Q168751 |
| North Carolina Central University | Q1518804 | ||
| P108 | employer | National Institutes of Health | Q390551 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development | Q5409765 | ||
| P735 | given name | Ida | Q644599 |
| Ida | Q644599 | ||
| P106 | occupation | physiologist | Q2055046 |
| biochemist | Q2919046 | ||
| P5008 | on focus list of Wikimedia project | WikiProject African diaspora | Q15304953 |
| P21 | sex or gender | female | Q6581072 |
| Q28326664 | 2,3,7,8-tetrachlorodibenzo-p-dioxin as cocarcinogen causing 3-methylcholanthrene-initiated subcutaneous tumors in mice genetically "nonresponsive" at Ah locus |
| Q28316402 | 2-Fluoro-L-histidine, an inhibitor of enzyme induction |
| Q71646397 | A comparison of the isoelectric points of mouse liver UDP-glucuronosyltransferase enzymes conjugating the twelve benzo[a]pyrene phenols |
| Q24337841 | A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini |
| Q72571462 | A phenylalanine codon deletion at the UGT1 gene complex locus of a Crigler-Najjar type I patient generates a pH-sensitive bilirubin UDP-glucuronosyltransferase |
| Q68673926 | Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver |
| Q42833801 | Aryl hydrocarcon hydroxylase and tyrosine aminotransferase activities in somatic-cell hybrids derived from hepatoma tissue culture HTC (rat) cells and 3T3 (mouse) benzo(a)pyrene-resistant cells |
| Q70473782 | Cell-free translation of mouse liver mRNA coding for two forms of UDP glucuronosyltransferase |
| Q28263969 | Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms |
| Q70496846 | Cleavage of nascent UDP glucuronosyltransferase from rat liver by dog pancreatic microsomes |
| Q33382413 | Cloning and expression of human liver UDP-glucuronosyltransferase cDNA, UDPGTh2. |
| Q24303831 | Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells. 3,4-catechol estrogens and estriol as primary substrates |
| Q47928550 | Coding defect and a TATA box mutation at the bilirubin UDP-glucuronosyltransferase gene cause Crigler-Najjar type I disease |
| Q79783289 | Comparison of glucuronidating activity of two human cDNAs, UDPGTh1 and UDPGTh2 |
| Q77951539 | Delayed response to phenobarbital treatment of a Crigler-Najjar type II patient with partially inactivating missense mutations in the bilirubin UDP-glucuronosyltransferase gene |
| Q66920810 | Deoxyribonucleic acid binding of 3-hydroxy- and 9-hydroxybenzo[a]pyrene following further metabolism by mouse liver microsomal cytochrome P1-450 |
| Q70461680 | Differences in UDP-glucuronosyltransferase activities in congenic inbred rats homozygous and heterozygous for the jaundice locus |
| Q70470796 | Differential induction and glycosylation of UDP-glucuronosyltransferase |
| Q33382415 | Expression of human liver 3, 4-catechol estrogens UDP-Glucuronosyltransferase cDNA in COS 1 cells |
| Q53501845 | Gene expression, ontogeny and transplacental induction of hepatic UDP-glucuronosyl transferase activity in mice. |
| Q73062776 | Genetic defects at the UGT1 locus associated with Crigler-Najjar type I disease, including a prenatal diagnosis |
| Q28259021 | Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications |
| Q39432183 | Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction |
| Q70945518 | Genetic regulation of bilirubin-UDP-glucuronosyltransferase induction by polycyclic aromatic compounds and phenobarbital in mice. Association with aryl hydrocarbon (benzo[a]pyrene) hydroxylase induction |
| Q77920429 | Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus |
| Q43599627 | Impact of prophylaxis for Mycobacterium avium complex on bacterial infections in patients with advanced human immunodeficiency virus disease. |
| Q69881839 | Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester |
| Q71215748 | Lobular distribution of human liver phenol and bilirubin uridine 5'-diphosphate glucuronosyltransferase messenger RNAs |
| Q37368001 | Low rate of CMV end-organ disease in HIV-infected patients despite low CD4+ cell counts and CMV viremia: results of ACTG protocol A5030. |
| Q36432386 | Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation |
| Q66920808 | Mutagenesis of certain benzo[a]pyrene phenols in vitro following further metabolism by mouse liver |
| Q70483159 | Purification and immunochemical characterization of a low-pI form of UDP glucuronosyltransferase from mouse liver |
| Q70445846 | Purification of a form of mouse liver UDP glucuronosyltransferase which glucuronidates androgens |
| Q42260992 | Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones. |
| Q47732343 | Required buried alpha-helical structure in the bilirubin UDP-glucuronosyltransferase, UGT1A1, contains a nonreplaceable phenylalanine |
| Q44786656 | Some aspects of mouse mammary gland development from maturity to early pregnancy |
| Q24311466 | The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence |
| Q48059211 | The novel UGT1 gene complex links bilirubin, xenobiotics, and therapeutic drug metabolism by encoding UDP-glucuronosyltransferase isozymes with a common carboxyl terminus |
| Q35223429 | The novel bilirubin/phenol UDP-glucuronosyltransferase UGT1 gene locus: implications for multiple nonhemolytic familial hyperbilirubinemia phenotypes |
| Q28204435 | Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus |
| Q28293767 | Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives |
| Q55062544 | UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. |
| Arabic (ar / Q13955) | أيدا ستيفين أونز | wikipedia |
| Ida Stephens Owens | wikipedia |
Search more.