PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification

scientific article

PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)63996-X
P3181OpenCitations bibliographic resource ID1477196
P932PMC publication ID1850320
P698PubMed publication ID11159191
P5875ResearchGate publication ID12170894

P50authorKristen JohnsonQ44839395
Hermann KalhoffQ64005991
Patrick SchauerteQ67186138
P2093author name stringA Superti-Furga
K Sano
R Terkeltaub
F Rutsch
H Kalhoff
W A Boisvert
B Maddux
S Vaingankar
I Goldfine
P2860cites workMutations in the gene encoding the human matrix Gla protein cause Keutel syndromeQ22008705
Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytesQ22010626
Role of the mouse ank gene in control of tissue calcification and arthritisQ22254612
Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 familyQ24308868
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Association of the human NPPS gene with ossification of the posterior longitudinal ligament of the spine (OPLL)Q28142507
Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activitiesQ28301252
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA proteinQ28304798
Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spineQ28505453
Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase)Q28589328
Ecto-enzymes: physiology meets pathologyQ33873171
Natural history of calcium deposits in atherosclerosis progression and regressionQ33894020
Tech.sight. Genetic testing--present and futureQ34049724
Idiopathic infantile arterial calcification: a case report and review of the literatureQ34261397
Idiopathic infantile arterial calcification: unusual featuresQ34268752
Idiopathic infantile arterial calcification with cardiac, renal and central nervous system involvementQ34521965
Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells.Q40951338
Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastomaQ41104567
Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1.Q42795833
Phosphocitrate inhibits a basic calcium phosphate and calcium pyrophosphate dihydrate crystal-induced mitogen-activated protein kinase cascade signal transduction pathwayQ42798382
Extracellular matrix calcification: where is the action?Q46291249
Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cellsQ46831739
Autotaxin, tumor motility-stimulating exophosphodiesteraseQ48055332
Keutel syndrome: further characterization and review.Q50504741
Arthritis and ankylosis in twy mice with hereditary multiple osteochondral lesions: with special reference to calcium deposition.Q50771981
Low levels of urinary inorganic pyrophosphate indicating systemic pyrophosphate deficiency in a boy with idiopathic infantile arterial calcification.Q52162692
Identification of B10, an alkaline phosphodiesterase of the apical plasma membrane of hepatocytes and biliary cells, in rat serum: increased levels following bile duct ligation and during the development of cholangiocarcinoma.Q53437411
Molecular determinants of arterial calcificationQ64049906
Idiopathic arterial calcification of infancy and pyrophosphate deficiencyQ70463159
A soluble PC-1 circulates in human plasma: relationship with insulin resistance and associated abnormalitiesQ73086790
Noncollagenous bone matrix proteins, calcification, and thrombosis in carotid artery atherosclerosisQ78121947
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectnucleoside-triphosphate diphosphatase activityQ21110155
Ectonucleotide pyrophosphatase/phosphodiesterase 1Q21110158
idiopathyQ594841
P304page(s)543-54
P577publication date2001-02-01
P1433published inThe American Journal of PathologyQ4744259
P1476titlePC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification
P478volume158

Reverse relations

cites work (P2860)
Q34163797A new Enpp1 allele, Enpp1(ttw-Ham), identified in an ICR closed colony
Q43070609A protective role for FGF-23 in local defence against disrupted arterial wall integrity?
Q54527062ATP acts as a survival signal and prevents the mineralization of aortic valve.
Q36642390Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hypertrophy and Mineralization After ACL Injuries In Vivo
Q36752273Advances in defining regulators of cementum development and periodontal regeneration
Q34168605Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice
Q38900801Alternatively activated macrophages exhibit an anticalcifying activity dependent on extracellular ATP/pyrophosphate metabolism
Q46296200Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA.
Q37791494Articular cartilage calcification in osteoarthritis: insights into crystal-induced stress.
Q24812372Association of ENPP1 gene polymorphisms with hand osteoarthritis in a Chuvasha population
Q54635726Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adults.
Q40437132Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate.
Q53089646Breast arterial calcification in chronic kidney disease: absence of smooth muscle apoptosis and osteogenic transdifferentiation.
Q35768694Calcium pyrophosphate dihydrate and basic calcium phosphate crystal-induced arthropathies: update on pathogenesis, clinical features, and therapy.
Q35126673Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: New developments relevant to the clinician
Q61927929Chapter 6 Vascular Calcification Inhibitors In Relation To Cardiovascular Disease With Special Emphasis On Fetuin‐A In Chronic Kidney Disease
Q24673657Characterisation of cartilage intermediate layer protein (CILP)-induced arthropathy in mice
Q26748812Characterisation of matrix vesicles in skeletal and soft tissue mineralisation
Q38646941Characterization and assessment of potential microRNAs involved in phosphate-induced aortic calcification.
Q46987166Chemical and hormonal determinants of vascular calcification in vitro.
Q35097443Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders
Q46012526Congenital Gaucher disease with nonimmune hydrops/erythroblastosis, infantile arterial calcification, and neonatal hepatitis/fibrosis. Clinicopathologic report with enzymatic and genetic analysis.
Q35126676Crystal deposition disease of the shoulder (including calcific tendonitis and milwaukee shoulder syndrome)
Q34222404Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
Q90029208Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
Q27343503ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
Q58102990ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP
Q41277036Effects of etidronate on the Enpp1⁻/⁻ mouse model of generalized arterial calcification of infancy
Q41354101Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions
Q34825300Enpp1: a potential facilitator of breast cancer bone metastasis
Q43242721Enzyme inhibition, radical scavenging, and spectroscopic studies of vanadium(IV)-hydrazide complexes
Q37294492Expression of NPP1 is regulated during atheromatous plaque calcification
Q58781123Extracellular ATP Regulates CD73 and ABCC6 Expression in HepG2 Cells
Q35559241Extracellular nucleotide metabolism and signaling in the pathophysiology of articular cartilage
Q53756234Extracellular pyrophosphate in the kidney: how does it get there and what does it do?.
Q35087040Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle
Q37584801FGF23 and syndromes of abnormal renal phosphate handling
Q41773869Generalized Arterial Calcification of Infancy: Fatal Clinical Course Associated with a Novel Mutation in ENPP1.
Q35671719Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6
Q41986289Generalized arterial calcification of infancy and pseudoxanthoma elasticum: two sides of the same coin
Q55040936Generalized arterial calcification of infancy: different clinical courses in two affected siblings.
Q55051449Generalized arterial calcification of infancy: phenotypic spectrum among three siblings including one case without obvious arterial calcifications.
Q34471170Generalized arterial calcification of infancy: two siblings with prolonged survival
Q82045563Genetic and enzymatic analysis for two Japanese patients with idiopathic infantile arterial calcification
Q36779445Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia
Q33352008Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel
Q28306935Hierarchies of extracellular matrix and mineral organization in bone of the craniofacial complex and skeleton
Q35853942Hip geometry variation is associated with bone mineralization pathway gene variants: The Framingham Study.
Q34514089Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs
Q24657630Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy
Q42113848Hypophosphatemic rickets developed after treatment with etidronate disodium in a patient with generalized arterial calcification in infancy
Q33474726Identification and characterization of novel tissue-nonspecific alkaline phosphatase inhibitors with diverse modes of action
Q24631251Idiopathic arterial calcification of infancy - a case report
Q47591462Idiopathic infantile arterial calcification in a 12-year-old girl presenting as chronic mesenteric ischemia: imaging findings and angioplasty results
Q34274117Idiopathic infantile arterial calcification: Sonographic findings
Q41977470Idiopathic infantile arterial calcification: a possible cause of refractory cardiopulmonary failure in infancy.
Q34519558Idiopathic infantile arterial calcification: clinical presentation, therapy and long-term follow-up
Q34486997Idiopathic infantile arterial calcification: imaging evaluation and the usefulness of MR angiography
Q34711868Idiopathic infantile arterial calcification: the spectrum of clinical presentations
Q34506946Idiopathic infantile arterial calcification: two case reports, a review of the literature and a role for cardiac transplantation.
Q37226131Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow
Q42516251Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms
Q36688447Interaction of vascular and bone disease in patients with normal renal function and patients undergoing dialysis
Q53657104Isolated pericardial effusion in the human fetus: a report of three cases.
Q26766350Large animal models of cardiovascular disease
Q43843547Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression
Q90329508Magnesium and Anti-phosphate Treatment with Bisphosphonates for Generalised Arterial Calcification of Infancy: A Case Report
Q35309274Matrix Gla protein metabolism in vascular smooth muscle and role in uremic vascular calcification
Q47647600Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models
Q35111872Metabolism of extracellular pyrophosphate
Q27680880Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke
Q35966637Molecular diagnosis of generalized arterial calcification of infancy (GACI)
Q34561450Molecular-pathogenetic classification of genetic disorders of the skeleton
Q42717983Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals
Q34217171Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification
Q28833749Nanomolar pyrophosphate detection and nucleus staining in living cells with simple terpyridine-Zn(II) complexes
Q33291152Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification
Q35161110Npp1 promotes atherosclerosis in ApoE knockout mice
Q28214273Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine
Q24301854One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist
Q35753562Osteogenic regulation of vascular calcification: an early perspective
Q93182236PXE, a Mysterious Inborn Error Clarified
Q35525230Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification
Q48016566Persistence of Vascular Calcification after Reversal of Uremia
Q44414003Phenolic glycosides from Symplocos racemosa: natural inhibitors of phosphodiesterase I
Q36943228Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification
Q34690795Phosphate sensing
Q26852872Phosphate/pyrophosphate and MV-related proteins in mineralisation: discoveries from mouse models
Q35920063Phosphate: known and potential roles during development and regeneration of teeth and supporting structures
Q105111046Phosphodiesterase Inhibitory Coumarinolignoids from Duranta repens
Q34769231Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification
Q35131762Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
Q35078539Plasma pyrophosphate and vascular calcification in chronic kidney disease
Q57070266Profile of asfotase alfa in the treatment of hypophosphatasia: design, development, and place in therapy
Q35156112Progressive ankylosis protein (ANK) in osteoblasts and osteoclasts controls bone formation and bone remodeling
Q34288709Purine receptors modulate chondrocyte extracellular inorganic pyrophosphate production
Q35247898Recent progress in the treatment of vascular calcification
Q36292246Regenerating the periodontium: is there a magic formula?
Q35699827Regulation of cardiovascular calcification
Q33727722Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia
Q48379638Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy.
Q96109756Skeletal abnormalities secondary to antenatal etidronate treatment for suspected generalised arterial calcification of infancy
Q51507079Smad3 plays an inhibitory role in phosphate-induced vascular smooth muscle cell calcification.
Q44838130Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1.
Q35083898Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice.
Q37218460T0901317, an LXR agonist, augments PKA-induced vascular cell calcification
Q33911294The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells
Q34402808The bone-vascular axis in chronic kidney disease.
Q34821047The mystery of persistent pulmonary hypertension: an idiopathic infantile arterial calcification
Q33775764The role of inorganic pyrophosphate in aortic valve calcification
Q36463221The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities
Q36602795The vascular phenotype in Pseudoxanthoma elasticum and related disorders: contribution of a genetic disease to the understanding of vascular calcification
Q38151635Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors
Q58087424Tissue Non-Specific Alkaline Phosphatase And Vascular Calcification: A Potential Therapeutic Target
Q34035649Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization
Q37325456Treatment of vascular calcification
Q38599585Treatment with pyrophosphate inhibits uremic vascular calcification
Q33603761Ultrastructural and biochemical aspects of matrix vesicle-mediated mineralization
Q50146523Ultrastructure and biological function of matrix vesicles in bone mineralization.
Q34165065Up-regulated expression of cartilage intermediate-layer protein and ANK in articular hyaline cartilage from patients with calcium pyrophosphate dihydrate crystal deposition disease
Q41697749Upregulation of IGF2 expression during vascular calcification
Q28565710Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification
Q41126480Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes
Q38671493Vascular Calcification in Uremia: New-Age Concepts about an Old-Age Problem
Q37195354Vascular calcification in chronic kidney disease: Pathogenesis and clinical implication
Q35021536Vascular calcification is dependent on plasma levels of pyrophosphate
Q28071582Vascular calcification: When should we interfere in chronic kidney disease patients and how?
Q79744868Vascular calcification: not so crystal clear
Q38796978Zooming in on the genesis of atherosclerotic plaque microcalcifications

Search more.