| scholarly article | Q13442814 |
| P50 | author | Sharad Kumar | Q37380153 |
| Kieran Harvey | Q43142384 | ||
| P2093 | author name string | D I Cook | |
| A Dinudom | |||
| P2860 | cites work | Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes | Q22001440 |
| Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel | Q24310075 | ||
| The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization | Q24314678 | ||
| Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4 | Q24532178 | ||
| Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination | Q24532806 | ||
| Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene | Q24562174 | ||
| WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome | Q24563029 | ||
| A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity | Q24564608 | ||
| Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+ | Q24647839 | ||
| Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach | Q24653749 | ||
| Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb | Q24685954 | ||
| Structure and regulation of amiloride-sensitive sodium channels | Q28137896 | ||
| All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+ | Q28142056 | ||
| Identification of a set of genes with developmentally down-regulated expression in the mouse brain | Q28187594 | ||
| Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel | Q28240272 | ||
| Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases | Q28240495 | ||
| Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome | Q28288744 | ||
| Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry | Q28304711 | ||
| Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC) | Q28575559 | ||
| Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits | Q29300859 | ||
| Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties | Q29620009 | ||
| Molecular cloning of Nedd4 from Xenopus laevis | Q30793518 | ||
| Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions | Q33632965 | ||
| Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome. | Q33843800 | ||
| The heterotetrameric architecture of the epithelial sodium channel (ENaC). | Q33888043 | ||
| A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system | Q34249821 | ||
| cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene. | Q34419826 | ||
| Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system. | Q37383490 | ||
| Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells | Q41188575 | ||
| Genotype-phenotype analysis of a newly discovered family with Liddle's syndrome | Q42666192 | ||
| Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4. | Q48898610 | ||
| Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome | Q48930629 | ||
| Subunit stoichiometry of the epithelial sodium channel | Q48939958 | ||
| Regulation of a cloned epithelial Na+ channel by its beta- and gamma-subunits | Q48947761 | ||
| The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis | Q48951069 | ||
| Control of the amiloride-sensitive Na+ current in mouse salivary ducts by intracellular anions is mediated by a G protein | Q70845742 | ||
| Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract | Q73085880 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | positive regulation of endocytosis | Q14862251 |
| NEDD4 like E3 ubiquitin protein ligase | Q21112132 | ||
| P304 | page(s) | 8597-601 | |
| P577 | publication date | 2001-03-16 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel | |
| P478 | volume | 276 |
| Q79761759 | 24-h ambulatory blood pressure is linked to chromosome 18q21-22 and genetic variation of NEDD4L associates with cross-sectional and longitudinal blood pressure in Swedes |
| Q83987131 | A clinical phenotype mimicking essential hypertension in a newly discovered family with Liddle's syndrome |
| Q42461529 | A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes |
| Q34081449 | A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila |
| Q34731561 | Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct |
| Q40762395 | Activation of large conductance sodium channels upon expression of amiloride-sensitive sodium channel in Sf9 insect cells |
| Q44374527 | Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel |
| Q34216316 | Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains |
| Q42602705 | Characterization of the human UBE3B gene: structure, expression, evolution, and alternative splicing |
| Q34194606 | Characterization of the interactions between Nedd4-2, ENaC, and sgk-1 using surface plasmon resonance |
| Q28566104 | Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays |
| Q34777003 | Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport |
| Q35994930 | Crystallization and preliminary X-ray diffraction studies of the WW4 domain of the Nedd4-2 ubiquitin-protein ligase |
| Q38598033 | Deletion of Nedd4-2 results in progressive kidney disease in mice |
| Q36949242 | Deubiquitylation regulates activation and proteolytic cleavage of ENaC |
| Q91698512 | Dietary sodium modulates nephropathy in Nedd4-2-deficient mice |
| Q73786040 | Differential expression and localisation of WWP1, a Nedd4-like protein, in epithelia |
| Q26825006 | Epithelial Na(+) channel regulation by cytoplasmic and extracellular factors |
| Q40081080 | Epithelial sodium channel exit from the endoplasmic reticulum is regulated by a signal within the carboxyl cytoplasmic domain of the alpha subunit |
| Q44396581 | Functional analysis of the human orthologue of the RSP5-encoded ubiquitin protein ligase, hNedd4, in yeast |
| Q43634951 | Gender difference in association of NEDD4L gene variants among southern Han Chinese with essential hypertension - a population-based case-control study. |
| Q50738677 | Genetic risk variants for dyslexia on chromosome 18 in a German cohort. |
| Q33517845 | Genetic variation of NEDD4L is associated with essential hypertension in female Kazakh general population: a case-control study |
| Q64080057 | HECT E3 Ligases: A Tale With Multiple Facets |
| Q30444132 | HECT E3s and human disease |
| Q91722534 | IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway |
| Q24322011 | Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L |
| Q33742226 | Identification of candidate genes for dyslexia susceptibility on chromosome 18. |
| Q34211983 | Identification of epistatic effects using a protein-protein interaction database |
| Q34251618 | Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype |
| Q34479835 | Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage |
| Q37025393 | Mechanisms and pharmacogenetic signals underlying thiazide diuretics blood pressure response |
| Q28594273 | N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein |
| Q38272580 | NEDD4-2 (NEDD4L): the ubiquitin ligase for multiple membrane proteins |
| Q40501781 | NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor |
| Q50134895 | NEDD4-2-dependent control of Na+ homeostasis and renal disease |
| Q38295075 | NEDD4: The founding member of a family of ubiquitin-protein ligases |
| Q34113703 | NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene. |
| Q34758977 | NEDD4L overexpression rescues the release and infectivity of human immunodeficiency virus type 1 constructs lacking PTAP and YPXL late domains |
| Q36769074 | Ndfip2 is a potential regulator of the iron transporter DMT1 in the liver |
| Q24651528 | Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions |
| Q34379768 | Nedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons |
| Q21129256 | Nedd4-2 and the regulation of epithelial sodium transport |
| Q34359643 | Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells |
| Q36571577 | Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel |
| Q39031391 | Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma |
| Q24534668 | Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression |
| Q29617293 | Physiological functions of the HECT family of ubiquitin ligases |
| Q33284000 | Polymorphism in NEDD4L is associated with increased salt sensitivity, reduced levels of P-renin and increased levels of Nt-proANP. |
| Q24555190 | Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells |
| Q35996407 | Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury |
| Q37693525 | Regulation of epithelial sodium channel trafficking by ubiquitination |
| Q37023709 | Regulation of the divalent metal ion transporter via membrane budding. |
| Q35010881 | Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11. |
| Q28564648 | Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein |
| Q40612889 | Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interference |
| Q50803754 | Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion. |
| Q34324276 | Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension |
| Q39893074 | Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC. |
| Q24629880 | Respiratory distress and perinatal lethality in Nedd4-2-deficient mice |
| Q28296575 | Role of the ubiquitin system in regulating ion transport |
| Q42609139 | Stimulation of Transepithelial Na + Current by Extracellular Gd 3+ in Xenopus laevis Alveolar Epithelium |
| Q47655027 | Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition |
| Q35691527 | The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture |
| Q37393354 | The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation |
| Q37176369 | The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism |
| Q38289604 | The impacts of the interaction of genetic variation, CYP11β2 and NEDD4L, with sodium intake on pediatric obesity with gender difference: a 3-year panel study |
| Q37416375 | The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels |
| Q47709454 | The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly |
| Q28217136 | Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel |
| Q39033646 | Ubiquitination and the Regulation of Membrane Proteins |
| Q64101960 | Ubiquitination as a Key Regulator of Endosomal Signaling by GPCRs |
| Q26863205 | Ubiquitylation and control of renal Na+ balance and blood pressure |
| Q28287425 | Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3 |
| Q44209009 | Where have all the Na+ channels gone? In search of functional ENaC in exocrine pancreas |
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