scholarly article | Q13442814 |
P50 | author | Ronny Drapkin | Q37843472 |
P2093 | author name string | W S Lane | |
D A Haber | |||
D M Livingston | |||
D W Bell | |||
S Ganesan | |||
S B Cantor | |||
D C Sgroi | |||
S Grossman | |||
D C Wahrer | |||
E M Kass | |||
P2860 | cites work | Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells | Q22003975 |
Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos | Q24302240 | ||
Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1 | Q24316865 | ||
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response | Q24316950 | ||
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. | Q41164271 | ||
Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines | Q41290495 | ||
Mammalian nucleotide excision repair and syndromes | Q41370274 | ||
Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation | Q41481294 | ||
Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps | Q47732509 | ||
BRCA1 protein products ... Functional motifs... | Q48062839 | ||
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. | Q52533204 | ||
BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene. | Q52537650 | ||
Transcriptional activation by BRCA1 | Q59072814 | ||
Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer | Q70812480 | ||
Location of BRCA1 in human breast and ovarian cancer cells | Q70998780 | ||
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3 | Q24321908 | ||
p53 modulation of TFIIH-associated nucleotide excision repair activity | Q24336880 | ||
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 | Q24609153 | ||
BRCA1 is a component of the RNA polymerase II holoenzyme | Q24675704 | ||
High-efficiency transformation of mammalian cells by plasmid DNA | Q27860469 | ||
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database | Q27861106 | ||
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder | Q28115238 | ||
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 | Q28115843 | ||
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response | Q28140763 | ||
Genetic analysis of BRCA1 function in a defined tumor cell line | Q28142643 | ||
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II | Q28251866 | ||
Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1 | Q28279796 | ||
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression | Q28282486 | ||
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor | Q28286827 | ||
Association of BRCA1 with Rad51 in mitotic and meiotic cells | Q28302118 | ||
The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility | Q28505195 | ||
Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH | Q28573627 | ||
Organization of SCP1 protein molecules within synaptonemal complexes of the rat | Q28574832 | ||
Brca1 controls homology-directed DNA repair | Q29614844 | ||
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage | Q29619360 | ||
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair | Q29619880 | ||
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties | Q29620009 | ||
DNA damage recognition during nucleotide excision repair in mammalian cells | Q31271134 | ||
Ten years of TFIIH. | Q33671312 | ||
Insights into the functions of BRCA1 and BRCA2. | Q33826737 | ||
Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum | Q33853150 | ||
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells | Q34503003 | ||
Evidence for a transcriptional activation function of BRCA1 C-terminal region | Q34736712 | ||
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation | Q36564865 | ||
Mutational analysis of ERCC3, which is involved in DNA repair and transcription initiation: identification of domains essential for the DNA repair function | Q38307435 | ||
SYBR Green I staining of pulsed field agarose gels is a sensitive and inexpensive way of quantitating DNA double-strand breaks in mammalian cells | Q39720624 | ||
Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription | Q40522919 | ||
Independence of R/M/N focus formation and the presence of intact BRCA1. | Q40864224 | ||
TFIIH: a key component in multiple DNA transactions | Q41099885 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | double-strand break repair | Q14818014 |
BRCA1 interacting protein C-terminal helicase 1 | Q21100487 | ||
BTB domain and CNC homolog 1 | Q21115419 | ||
P304 | page(s) | 149-160 | |
P577 | publication date | 2001-04-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function | |
P478 | volume | 105 |
Q42627861 | 17q23.2q23.3 de novo duplication in association with speech and language disorder, learning difficulties, incoordination, motor skill impairment, and behavioral disturbances: a case report. |
Q38357627 | A ChIP-chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response |
Q38018068 | A DOG's View of Fanconi Anemia: Insights from C. elegans |
Q30100995 | A never-ending story: the steadily growing family of the FA and FA-like genes |
Q55639040 | A new bioinformatics tool to help assess the significance of BRCA1 variants. |
Q36922848 | A novel breast cancer-associated BRIP1 (FANCJ/BACH1) germ-line mutation impairs protein stability and function |
Q37081107 | A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer |
Q39980425 | A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens |
Q24644321 | A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome |
Q39758925 | A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein |
Q37120616 | A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck |
Q39019991 | Aberrant DNA methylation status of DNA repair genes in breast cancer treated with neoadjuvant chemotherapy |
Q24306765 | Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response |
Q40804151 | Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase |
Q63432940 | Age-related gene and miRNA expression changes in airways of healthy individuals |
Q92240524 | An Arabidopsis FANCJ helicase homologue is required for DNA crosslink repair and rDNA repeat stability |
Q39639572 | An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy |
Q28115512 | An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification |
Q37097543 | Analysis of BRIP1 Variants among Korean Patients with BRCA1/2 Mutation-Negative High-Risk Breast Cancer |
Q33342762 | Analysis of the DNA binding activity of BRCA1 and its modulation by the tumour suppressor p53. |
Q24301530 | Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer |
Q37624182 | Assembly of checkpoint and repair machineries at DNA damage sites |
Q37775585 | Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair |
Q43497475 | Association between BRIP1 (BACH1) polymorphisms and breast cancer risk: a meta-analysis |
Q60934669 | Association of Single-Nucleotide Polymorphisms in Monoubiquitinated FANCD2-DNA Damage Repair Pathway Genes With Breast Cancer in the Chinese Population |
Q25257890 | BACH1 Ser919Pro variant and breast cancer risk |
Q82488305 | BACH1 is a DNA repair protein supporting BRCA1 damage response |
Q33531604 | BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control |
Q27487849 | BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1 |
Q57753005 | BLM's balancing act and the involvement of FANCJ in DNA repair |
Q37770591 | BRCA1 16 years later: DNA damage-induced BRCA1 shuttling |
Q36174109 | BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells |
Q92570468 | BRCA1 and BRCA2 Gene Expression: Diurnal Variability and Influence of Shift Work |
Q81042311 | BRCA1 and BRCA2 in breast cancer predisposition and recombination control |
Q34521769 | BRCA1 and BRCA2 in hereditary breast cancer |
Q34345297 | BRCA1 and BRCA2: 1994 and beyond |
Q34110729 | BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair |
Q37149848 | BRCA1 and BRCA2: different roles in a common pathway of genome protection |
Q38931388 | BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1 |
Q39218335 | BRCA1 and Its Network of Interacting Partners |
Q37507563 | BRCA1 and its toolbox for the maintenance of genome integrity |
Q35298530 | BRCA1 and p53: compensatory roles in DNA repair |
Q30480563 | BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin |
Q28267880 | BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220 |
Q47836565 | BRCA1 gene: function and deficiency |
Q35546588 | BRCA1 in hormone-responsive cancers |
Q24297493 | BRCA1 interacts with FHL2 and enhances FHL2 transactivation function |
Q42809714 | BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains |
Q40266057 | BRCA1 interacts with poly(A)-binding protein: implication of BRCA1 in translation regulation |
Q44373387 | BRCA1 point mutations in premenopausal breast cancer patients from Central Sudan. |
Q35153726 | BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair |
Q24316340 | BRCA1 supports XIST RNA concentration on the inactive X chromosome |
Q35861690 | BRCA1 tumor suppressor network: focusing on its tail |
Q34539782 | BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability |
Q52617694 | BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1. |
Q40424257 | BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II. |
Q33284720 | BRIP1 (BACH1) variants and familial breast cancer risk: a case-control study |
Q41925341 | BRIP1 coding variants are associated with a high risk of hepatocellular carcinoma occurrence in patients with HCV- or HBV-related liver disease |
Q36502747 | BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity |
Q47128752 | BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes |
Q54603929 | BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer. |
Q37735947 | BRIP1/FANCJ Mutation Analysis in a Family with History of Male and Female Breast Cancer in India |
Q61448013 | Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination |
Q36108626 | Breast cancer susceptibility and the DNA damage response |
Q37406868 | Breast cancer-associated Abraxas mutation disrupts nuclear localization and DNA damage response functions |
Q40104298 | CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response |
Q24321418 | CCDC98 targets BRCA1 to DNA damage sites |
Q28387717 | CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly. |
Q24802534 | Cancer incidence in relatives of a population-based set of cases of early-onset breast cancer with a known BRCA1 and BRCA2 mutation status |
Q34412496 | Cancer suppression by the chromosome custodians, BRCA1 and BRCA2. |
Q28217784 | Cancer susceptibility and the functions of BRCA1 and BRCA2 |
Q49685857 | Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar. |
Q28116217 | Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci |
Q28252640 | Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights |
Q28553736 | Characterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor Design |
Q42441246 | Characterization of the DNA damage-inducible helicase DinG from Escherichia coli. |
Q28277364 | Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 |
Q47104467 | Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition |
Q27938640 | Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae |
Q27932943 | Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion |
Q37310881 | Choreography of recombination proteins during the DNA damage response |
Q26828639 | Close encounters for the first time: Helicase interactions with DNA damage |
Q36104862 | Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1. |
Q39398050 | Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing |
Q24537451 | Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation |
Q38933663 | Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells |
Q37207378 | Correlation of the BACH1 Pro919Ser polymorphism with breast cancer risk: A literature-based meta-analysis and meta-regression analysis |
Q39668567 | Cortical neurons gradually attain a post-mitotic state. |
Q38981181 | Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses |
Q53815410 | CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. |
Q91964143 | DNA Helicases as Safekeepers of Genome Stability in Plants |
Q37127343 | DNA crosslinking damage and cancer - a tale of friend and foe. |
Q37742898 | DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints |
Q24306945 | DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains |
Q36044809 | DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster |
Q35961526 | DNA helicases associated with genetic instability, cancer, and aging |
Q93102659 | DNA- and DNA-Protein-Crosslink Repair in Plants |
Q36483479 | DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair |
Q50416430 | Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1. |
Q35859458 | Deciphering the BRCA1 Tumor Suppressor Network |
Q33879073 | Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells |
Q46850561 | Detecting protein-protein interactions by Far western blotting |
Q40890323 | Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India |
Q47577422 | Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations |
Q73874204 | Dhh1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression in yeast |
Q40614873 | Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation |
Q36840167 | Discovering interactions among BRCA1 and other candidate genes associated with sporadic breast cancer |
Q39170653 | Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray. |
Q49622066 | Discovery of cell-type specific DNA motif grammar in cis-regulatory elements using random Forest. |
Q26828898 | Disease-causing missense mutations in human DNA helicase disorders |
Q44052691 | Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. |
Q37631820 | Dissecting the chromatin interactome of microRNA genes. |
Q24802157 | Distinct functions of BRCA1 and BRCA2 in double-strand break repair |
Q33312344 | Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction |
Q50287350 | EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment |
Q27332013 | Emerging critical roles of Fe-S clusters in DNA replication and repair |
Q92103705 | Epithelial ovarian cancer risk: A review of the current genetic landscape |
Q35476330 | Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems |
Q35445886 | Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design |
Q45521062 | Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy |
Q35801606 | FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway |
Q28250124 | FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures |
Q33289084 | FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein |
Q36952290 | FANCJ at the FORK. |
Q36732772 | FANCJ couples replication past natural fork barriers with maintenance of chromatin structure |
Q41628920 | FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids. |
Q36710804 | FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability |
Q37391123 | FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress |
Q30863349 | FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner |
Q39922407 | FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts |
Q39042130 | FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation |
Q38285873 | FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation. |
Q37134364 | FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange |
Q34335528 | FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response |
Q39672854 | FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses. |
Q37271577 | FANCM-FAAP24 and FANCJ: FA proteins that metabolize DNA. |
Q37870047 | FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair |
Q38871644 | Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage |
Q37217527 | Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function |
Q28513158 | FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice |
Q42681613 | FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. |
Q39537982 | FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells |
Q36602573 | Fanconi anaemia genes and susceptibility to cancer |
Q83572053 | Fanconi anemia |
Q35645191 | Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction |
Q57499930 | Fanconi anemia and breast cancer susceptibility meet again |
Q34636203 | Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response |
Q34310865 | Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. |
Q33368942 | Fanconi anemia proteins stabilize replication forks |
Q37069628 | Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy |
Q51768232 | Four common polymorphisms of BRIP1 (rs2048718, rs4988344, rs4986764, and rs6504074) and cancer risk: evidence from 13,716 cancer patients and 15,590 cancer-free controls. |
Q35869772 | Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics |
Q33688407 | Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance |
Q35775886 | Functional assays for BRCA1 and BRCA2. |
Q34029275 | Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest |
Q33946999 | Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development |
Q28469139 | Functional impact of missense variants in BRCA1 predicted by supervised learning |
Q37336936 | G-quadruplex recognition and remodeling by the FANCJ helicase |
Q34554709 | Gene expression in inherited breast cancer |
Q33396559 | Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer |
Q89659606 | Genetic Predisposition to Breast and Ovarian Cancers: How Many and Which Genes to Test? |
Q64388164 | Genetic instability in the RAD51 and BRCA1 regions in breast cancer |
Q24621899 | Genome-wide comprehensive analysis of human helicases |
Q51690290 | Germline mutations in DNA repair genes may predict neoadjuvant therapy response in triple negative breast patients. |
Q26744714 | Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles |
Q34073316 | G‐quadruplex nucleic acids and human disease |
Q38736259 | HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks |
Q34396861 | HapScope: a software system for automated and visual analysis of functionally annotated haplotypes |
Q34659857 | Helicase-inactivating mutations as a basis for dominant negative phenotypes |
Q35029638 | Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1. |
Q36978755 | Hereditary breast cancer in the Han Chinese population. |
Q37720239 | Heterochromatin DNA replication and Rif1. |
Q64111167 | Holding All the Cards-How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability |
Q28085364 | Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins |
Q97904814 | Homologous repair deficiency score for identifying breast cancers with defective DNA damage response |
Q24634556 | How the fanconi anemia pathway guards the genome |
Q56552038 | Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity |
Q21263027 | Human single-stranded DNA binding proteins are essential for maintaining genomic stability |
Q35997630 | Impact of RING and BRCT Domain Mutations on BRCA1 Protein Stability, Localization and Recruitment to DNA Damage |
Q37861028 | Inherited mutations in breast cancer genes--risk and response |
Q35545841 | Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand. |
Q92853298 | Inhibition of Karyopherin-α2 Augments Radiation-Induced Cell Death by Perturbing BRCA1-Mediated DNA Repair |
Q100503057 | Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells |
Q33675765 | Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutations |
Q24337192 | Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome |
Q33838817 | Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism |
Q26753126 | Interplay between Fanconi anemia and homologous recombination pathways in genome integrity |
Q36005906 | Irreversible binding of an anticancer compound (BI-94) to plasma proteins |
Q36952019 | Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations |
Q34036642 | Long-range massively parallel mate pair sequencing detects distinct mutations and similar patterns of structural mutability in two breast cancer cell lines |
Q50287351 | Long-range resection of DNA DSBs by EXO1 or DNA2 |
Q34336205 | Loss of BRCA1-A complex function in RAP80 null tumor cells |
Q34989634 | Loss of the BRCA1-interacting helicase BRIP1 results in abnormal mammary acinar morphogenesis |
Q24317291 | MERIT40 facilitates BRCA1 localization and DNA damage repair |
Q28067393 | Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 |
Q36219554 | Mechanisms of BRCA1 tumor suppression |
Q36573932 | Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability |
Q34521150 | Mechanisms of helicases |
Q37263648 | Mechanisms of sister chromatid pairing |
Q36870879 | Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2). |
Q51125378 | MicroRNA-543 acts as a prognostic marker and promotes the cell proliferation in cervical cancer by BRCA1-interacting protein 1. |
Q59465999 | Microfluidics: Rapid Diagnosis for Breast Cancer |
Q28294399 | Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks |
Q28274000 | Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis |
Q34377302 | Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia |
Q27666163 | Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control |
Q27016169 | Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome |
Q33858073 | Molecular genetics complexity impeding research progress in breast and ovarian cancers |
Q28207872 | Molecular views of recombination proteins and their control |
Q49646612 | Multifaceted Fanconi Anemia Signaling. |
Q34324063 | Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes |
Q37356517 | Multimodal assessment of protein functional deficiency supports pathogenicity of BRCA1 p.V1688del |
Q51527655 | Mutation analysis of BRIP1 in male breast cancer cases: a population-based study in Central Italy. |
Q25257392 | Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer |
Q34491545 | Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining |
Q47141035 | Mutation status of RAD51C, PALB2 and BRIP1 in 100 Japanese familial breast cancer cases without BRCA1 and BRCA2 mutations |
Q38815816 | Mutational analysis of FANCJ helicase. |
Q28188416 | Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals |
Q39991531 | Mutational analysis of the breast cancer susceptibility gene BRIP1 /BACH1/FANCJ in high-risk non-BRCA1/BRCA2 breast cancer families |
Q28249514 | Mutations in BRIP1 confer high risk of ovarian cancer |
Q90485059 | Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Cancer Surveillance in Fanconi Anemia |
Q34348715 | New complexities for BRCA1 and BRCA2. |
Q36883664 | New insights into breast cancer genetics and impact on patient management |
Q37149784 | New players in the BRCA1-mediated DNA damage responsive pathway |
Q38184454 | Next-generation sequencing for inherited breast cancer risk: counseling through the complexity |
Q33456377 | Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank. |
Q28207250 | No evidence of involvement of germline BACH1 mutations in Finnish breast and ovarian cancer families |
Q37079859 | No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing |
Q28211127 | No mutations in the BACH1 gene in BRCA1 and BRCA2 negative breast-cancer families linked to 17q22 |
Q59539038 | No mutations in theXRCC2gene inBRCA1/2-negative high-risk breast cancer families |
Q33931112 | Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner |
Q34487109 | On the birth of breast cancer |
Q35621531 | Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence. |
Q38129725 | Opportunities and hurdles in the treatment of BRCA1-related breast cancer |
Q57752957 | Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress |
Q38013077 | Oxidative stress in Fanconi anaemia: from cells and molecules towards prospects in clinical management |
Q24316113 | PALB2 is an integral component of the BRCA complex required for homologous recombination repair |
Q24322952 | PALB2 regulates recombinational repair through chromatin association and oligomerization |
Q27649882 | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach |
Q28297156 | Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response |
Q28212425 | Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains |
Q26999072 | Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif |
Q41133980 | Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population. |
Q47683530 | Polymorphisms in BRCA1, BRCA1-interacting genes and susceptibility of breast cancer in Chinese women |
Q35619722 | Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae. |
Q27690911 | Postreplicative mismatch repair |
Q35833998 | Protein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stability |
Q51311489 | Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. |
Q37800769 | RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer |
Q92608468 | RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci |
Q36080420 | RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo |
Q24306789 | RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites |
Q34762756 | RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci |
Q41808393 | RAS, cellular senescence and transformation: the BRCA1 DNA repair pathway at the crossroads |
Q33378036 | Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku80 |
Q47259551 | RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions |
Q64055629 | Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms |
Q38985539 | Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia |
Q37120275 | Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network |
Q28214575 | Recombinational DNA repair and human disease |
Q28212699 | Redistribution of BRCA1 among four different protein complexes following replication blockage |
Q41781885 | Redox control of the DNA damage-inducible protein DinG helicase activity via its iron-sulfur cluster |
Q33886979 | Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications |
Q35678377 | Rescue of replication failure by Fanconi anaemia proteins |
Q44324983 | Rewiring the dynamic interactome |
Q37775588 | Role of homologous recombination in DNA interstrand crosslink repair |
Q28191496 | SUVi and BACH1: a new subfamily of mammalian helicases? |
Q22000758 | Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals |
Q54423137 | Screening for large genomic rearrangements of the BRIP1 and CHK1 genes in Finnish breast cancer families. |
Q28606408 | Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis |
Q39931246 | Sequence conservation and differential expression of Marek's disease virus microRNAs |
Q30491608 | Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase |
Q38292340 | Single-molecule sorting of DNA helicases |
Q38987499 | Sp1 is necessary for gene activation of Adamts17 by estrogen |
Q35604035 | Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation |
Q36333360 | Structural basis for phosphorylation-dependent signaling in the DNA-damage response |
Q24628641 | Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains |
Q40557832 | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. |
Q39494743 | Structural characterization of BRCT-tetrapeptide binding interactions. |
Q27639943 | Structural consequences of a cancer-causing BRCA1-BRCT missense mutation |
Q24651980 | Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1 |
Q28260830 | Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer |
Q38326236 | Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites |
Q24292396 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure |
Q29031393 | Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide |
Q92116582 | Structure-Guided Synthesis and Evaluation of Small-Molecule Inhibitors Targeting Protein-Protein Interactions of BRCA1 tBRCT Domain |
Q62937915 | Studies of TBX4 and chromosome 17q23.1q23.2: an uncommon cause of nonsyndromic clubfoot |
Q37178493 | Superfamily 2 helicases |
Q64119152 | Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci |
Q24514481 | TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage |
Q33277172 | Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer |
Q34865929 | Tandem BRCT Domains: DNA's Praetorian Guard. |
Q39736886 | Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass |
Q37161449 | Telomeres do the (un)twist: helicase actions at chromosome termini |
Q34194407 | Telomeres: structures in need of unwinding |
Q35130683 | The 17q23 amplicon and breast cancer |
Q37124472 | The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50. |
Q40486944 | The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci |
Q24622650 | The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations |
Q34560326 | The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia |
Q34543616 | The BRCA2-EMSY connection: implications for breast and ovarian tumorigenesis |
Q24298428 | The BRCT Domain Is a Phospho-Protein Binding Domain |
Q40382210 | The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair |
Q55671102 | The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J |
Q54443591 | The DinG protein from Escherichia coli is a structure-specific helicase. |
Q24312784 | The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells |
Q35024542 | The Fanconi anemia pathway and ICL repair: implications for cancer therapy |
Q28756516 | The Fanconi anemia pathway and ubiquitin |
Q37356265 | The Fanconi anemia protein interaction network: casting a wide net. |
Q34170774 | The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization |
Q37417960 | The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment |
Q36052367 | The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function |
Q36982306 | The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia |
Q89866885 | The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication |
Q39082111 | The budding yeast protein Chl1p is required to preserve genome integrity upon DNA damage in S-phase |
Q64089437 | The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors |
Q40307700 | The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest |
Q38805624 | The excluded DNA strand is SEW important for hexameric helicase unwinding |
Q74420964 | The genome's best friend |
Q47160579 | The helicase DinG responds to stress due to DNA double strand breaks |
Q46888893 | The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction |
Q34163219 | The relationship between the roles of BRCA genes in DNA repair and cancer predisposition |
Q58084799 | The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans |
Q42065210 | The ubiquitin E3 ligase activity of BRCA1 and its biological functions. |
Q38065578 | The yin and yang of repair mechanisms in DNA structure-induced genetic instability |
Q35730286 | Tracing the network connecting BRCA and Fanconi anaemia proteins |
Q33373567 | Transcription factor and microRNA regulation in androgen-dependent and -independent prostate cancer cells |
Q38375832 | Transcriptome analyses of rhesus monkey preimplantation embryos reveal a reduced capacity for DNA double-strand break repair in primate oocytes and early embryos |
Q92644000 | Transcriptome profiling revealed multiple genes and ECM-receptor interaction pathways that may be associated with breast cancer |
Q47567895 | Translational opportunities for broad-spectrum natural phytochemicals and targeted agent combinations in breast cancer |
Q33720531 | Triple helix-interacting proteins and cancer |
Q56625730 | Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles |
Q28249114 | Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155 |
Q43764686 | Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes |
Q38190273 | Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers. |
Q90072078 | USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells |
Q81138696 | Unraveling the Fanconi anemia-DNA repair connection |
Q28756062 | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
Q37577923 | Update on genetic predisposition to breast cancer |
Q42004182 | WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase |
Q37144651 | Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins |
Q42020935 | Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer |
Q35883840 | hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. |
Search more.