review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Tom Blundell | Q7814993 |
Qian Wu | Q57451839 | ||
Harry Jubb | Q42822785 | ||
P2860 | cites work | BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function | Q24291119 |
The BRCT Domain Is a Phospho-Protein Binding Domain | Q24298428 | ||
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response | Q24306765 | ||
CCDC98 targets BRCA1 to DNA damage sites | Q24321418 | ||
Structure of an XRCC1 BRCT domain: a new protein-protein interaction module | Q24533379 | ||
BRCT domains: easy as one, two, three | Q24635835 | ||
Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1 | Q24651980 | ||
Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1 | Q27635011 | ||
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation | Q27639943 | ||
Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIβ binding protein 1 | Q27658324 | ||
Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1 | Q27659872 | ||
Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition | Q27667456 | ||
Structural basis for the BRCA1 BRCT interaction with the proteins ATRIP and BAAT1 | Q27686827 | ||
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 | Q28115843 | ||
Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA | Q28145077 | ||
Detection of multiscale pockets on protein surfaces using mathematical morphology. | Q51773359 | ||
Left-handed polyproline II helices commonly occur in globular proteins. | Q52402236 | ||
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening | Q63363987 | ||
The BRCT regions of tumor suppressor BRCA1 and of XRCC1 show DNA end binding activity with a multimerizing feature | Q64388283 | ||
Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core | Q71532382 | ||
Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins | Q73034981 | ||
Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design | Q80764882 | ||
Stereochemistry of polypeptide chain configurations | Q28190300 | ||
BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting | Q28212263 | ||
Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains | Q28212425 | ||
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling | Q28260142 | ||
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer | Q28260830 | ||
Linkage of early-onset familial breast cancer to chromosome 17q21 | Q28268902 | ||
Interactions between BRCT repeats and phosphoproteins: tangled up in two | Q28289371 | ||
DNA-PK: the means to justify the ends? | Q28305446 | ||
Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide | Q29031393 | ||
Analysis of membrane and surface protein sequences with the hydrophobic moment plot | Q29618183 | ||
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins | Q29619879 | ||
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair | Q29619880 | ||
Charting the landscape of tandem BRCT domain-mediated protein interactions | Q33782757 | ||
BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle | Q34313012 | ||
Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families | Q34321216 | ||
Tandem BRCT Domains: DNA's Praetorian Guard. | Q34865929 | ||
Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design | Q35445886 | ||
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. | Q37235809 | ||
Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells | Q37254703 | ||
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity | Q37524847 | ||
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. | Q40557832 | ||
CREDO: a structural interactomics database for drug discovery | Q42119055 | ||
Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1. | Q42761664 | ||
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. | Q46651078 | ||
BRCA1 protein products ... Functional motifs... | Q48062839 | ||
BRCA1 mutations in primary breast and ovarian carcinomas | Q48078473 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2-3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | peptide | Q172847 |
DNA damage | Q5205747 | ||
transcription factor | Q407384 | ||
phosphoprotein | Q423934 | ||
nuclear protein | Q16860021 | ||
chemical model | Q25109595 | ||
biomedical investigative technique | Q66648976 | ||
neoplasm protein | Q66894191 | ||
Fanconi anemia complementation group proteins | Q77044783 | ||
P304 | page(s) | 143-8 | |
P577 | publication date | 2015-03-01 | |
P1433 | published in | Progress in Biophysics and Molecular Biology | Q15753863 |
P1476 | title | Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif | |
P478 | volume | 117 |
Q55639040 | A new bioinformatics tool to help assess the significance of BRCA1 variants. |
Q50329367 | ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair |
Q90581419 | DNA breakpoint assay reveals a majority of gross duplications occur in tandem reducing VUS classifications in breast cancer predisposition genes |
Q37367852 | Dynamic structures in DNA damage responses & cancer. |
Q49936294 | Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development. |
Q57826033 | Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer |
Q37693410 | Identification of recurrent BRCA1 mutation and its clinical relevance in Chinese Triple-negative breast cancer cohort |
Q38326236 | Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites |
Q57029697 | The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection |
Q58084799 | The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans |
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