| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.C100144200 |
| P698 | PubMed publication ID | 11331269 |
| P2093 | author name string | L E Maquat | |
| E A Thompson | |||
| L Jamieson | |||
| A P Fields | |||
| G Denning | |||
| P2860 | cites work | Mammalian orthologues of a yeast regulator of nonsense transcript stability | Q24313065 |
| Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein | Q24336236 | ||
| DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product | Q24337388 | ||
| SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast | Q24554452 | ||
| The Schizosaccharomyces pombe rad3 checkpoint gene | Q24561779 | ||
| Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo | Q24650917 | ||
| Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates | Q27860715 | ||
| PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints | Q27934828 | ||
| The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus | Q28257161 | ||
| Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro | Q28261009 | ||
| RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Q28286431 | ||
| Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway | Q28352632 | ||
| Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue | Q28367688 | ||
| Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction | Q28378871 | ||
| A perfect message: RNA surveillance and nonsense-mediated decay | Q29616125 | ||
| Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression | Q29616821 | ||
| Nonsense-mediated mRNA decay in health and disease | Q29619553 | ||
| Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin | Q29620399 | ||
| Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells | Q29620524 | ||
| RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer | Q33546909 | ||
| Telomere length regulation and telomeric chromatin require the nonsense-mediated mRNA decay pathway | Q33781130 | ||
| TOR kinase homologs function in a signal transduction pathway that is conserved from yeast to mammals | Q33784149 | ||
| Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA. | Q33786578 | ||
| Mechanisms of mRNA surveillance in eukaryotes | Q33847689 | ||
| Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome | Q33959686 | ||
| Quality control of mRNA function | Q34156109 | ||
| Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans | Q35202203 | ||
| Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. | Q35909879 | ||
| A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells | Q36283006 | ||
| Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control | Q36490482 | ||
| When is a lipid kinase not a lipid kinase? When it is a protein kinase | Q40410589 | ||
| The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression | Q40975191 | ||
| Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints | Q41063544 | ||
| Nonsense surveillance in lymphocytes? | Q41716349 | ||
| Structure and function of phosphoinositide 3-kinases. | Q52532836 | ||
| FAT: a novel domain in PIK-related kinases | Q57444244 | ||
| mRNA surveillance by the Caenorhabditis elegans smg genes | Q72234045 | ||
| P433 | issue | 25 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphatidylinositol phosphate biosynthetic process | Q14887688 |
| SMG1 nonsense mediated mRNA decay associated PI3K related kinase | Q21134874 | ||
| P304 | page(s) | 22709-14 | |
| P577 | publication date | 2001-06-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein | |
| P478 | volume | 276 |
| Q33374003 | A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans |
| Q39648391 | A protective role for the human SMG-1 kinase against tumor necrosis factor-alpha-induced apoptosis |
| Q34182070 | A role for nonsense-mediated mRNA decay in plants: pathogen responses are induced in Arabidopsis thaliana NMD mutants |
| Q29547735 | ATM and related protein kinases: safeguarding genome integrity |
| Q52581123 | Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. |
| Q24311198 | An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay |
| Q54303567 | Analysis of nonsense-mediated mRNA decay in mammalian cells. |
| Q36052569 | Balancing Arc synthesis, mRNA decay, and proteasomal degradation: maximal protein expression triggered by rapid eye movement sleep-like bursts of muscarinic cholinergic receptor stimulation. |
| Q35950217 | Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons |
| Q24293459 | Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. |
| Q37371781 | Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways |
| Q39323825 | Control of gene expression through the nonsense-mediated RNA decay pathway |
| Q91292192 | Cryo-EM structure of SMG1-SMG8-SMG9 complex |
| Q24297565 | DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans |
| Q24817164 | Differential gene expression in HIV/SIV-associated and spontaneous lymphomas |
| Q28214407 | Divergent origins and concerted expansion of two segmental duplications on chromosome 16 |
| Q33566949 | Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival. |
| Q92549160 | Glomerular Proteomic Profiles in the NZB/W F1 Hybrid Mouse Model of Lupus Nephritis |
| Q24304228 | Human INT6/eIF3e is required for nonsense-mediated mRNA decay |
| Q24316203 | Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay |
| Q40179946 | Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies |
| Q44241759 | Inferring protein function from genomic sequence: Giardia lamblia expresses a phosphatidylinositol kinase-related kinase similar to yeast and mammalian TOR. |
| Q29028235 | Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII |
| Q91621722 | InsP6 binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex |
| Q33437371 | Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia |
| Q35097691 | Looking at mRNA decay pathways through the window of molecular evolution |
| Q34206662 | Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1 |
| Q40572900 | Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway |
| Q26771669 | Mechanism and regulation of the nonsense-mediated decay pathway |
| Q38568755 | Mechanism, factors, and physiological role of nonsense-mediated mRNA decay. |
| Q53009055 | MicroRNA-585 acts as a tumor suppressor in non-small-cell lung cancer by targeting hSMG-1. |
| Q37675497 | NMD: a multifaceted response to premature translational termination |
| Q37325822 | NMD: multitasking between mRNA surveillance and modulation of gene expression |
| Q36052204 | Navigating without a road map |
| Q35296033 | New insights into the formation of active nonsense-mediated decay complexes. |
| Q89068594 | Nonsense-Mediated mRNA Decay Begins Where Translation Ends |
| Q28082699 | Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story |
| Q41348981 | Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival |
| Q34366609 | Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets |
| Q24671607 | Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways |
| Q37622077 | Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors |
| Q35133708 | Nonsense-mediated mRNA decay: insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins |
| Q27015298 | Nonsense-mediated mRNA decay: inter-individual variability and human disease |
| Q26750271 | Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact |
| Q29616134 | Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics |
| Q27684654 | Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6 |
| Q24300529 | Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7 |
| Q52667237 | Positional cloning of a cyromazine resistance gene in Drosophila melanogaster. |
| Q36287491 | RNAi and RNA-based regulation of immune system function |
| Q24644623 | Rapamycin and mTOR kinase inhibitors |
| Q38048705 | Regulation of nonsense-mediated mRNA decay |
| Q43785527 | Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway |
| Q27935545 | Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay |
| Q27334311 | SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians |
| Q47295086 | SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling |
| Q37349465 | SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA Decay in Caenorhabditis elegans |
| Q46329882 | SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia |
| Q37525832 | SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways |
| Q34463782 | SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. |
| Q50295873 | SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) |
| Q24302039 | SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay |
| Q24310484 | SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan |
| Q24295213 | SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway |
| Q30311841 | Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E. |
| Q36988764 | Signaling pathways that control mRNA turnover |
| Q33982260 | Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay |
| Q34416344 | Stop making nonSense: the C. elegans smg genes |
| Q95941526 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity |
| Q35232574 | The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA. |
| Q38341790 | The conformational plasticity of eukaryotic RNA-dependent ATPases |
| Q24537105 | The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling |
| Q24294881 | The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells |
| Q37013877 | The multiple lives of NMD factors: balancing roles in gene and genome regulation |
| Q28248816 | The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3 |
| Q27938201 | Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast |
| Q37628239 | Virus Escape and Manipulation of Cellular Nonsense-Mediated mRNA Decay |
| Q37118988 | hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress |
| Q43203528 | hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay |
| Q36833036 | mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons. |
| Q35560399 | mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia |
Search more.