Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

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Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCB.1196
P698PubMed publication ID11500939

P50authorRiccardo VigneriQ53279376
Pierluigi ScaliaQ71126558
P2093author name stringL Comai
C K Sung
E Heart
P2860cites workIsolation of an AP-1 repressor by a novel method for detecting protein-protein interactionsQ24646252
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseQ24682825
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BQ27860731
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase BalphaQ28616168
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.Q30452681
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.Q33858986
The insulin-like growth factor family of ligands, receptors, and binding proteinsQ35343968
Insulin-like growth factor II stimulates cell proliferation through the insulin receptorQ36105416
Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblastsQ36653985
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activityQ38336655
Inhibition of glycogen synthase kinase-3 by insulin in cultured human skeletal muscle myoblastsQ41343940
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated proteQ41437636
Mechanisms and consequences of activation of protein kinase B/AktQ41751003
Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signallingQ42032355
Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.Q42811852
Insulin-stimulated expression of c-fos, fra1 and c-jun accompanies the activation of the activator protein-1 (AP-1) transcriptional complex.Q42991723
A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesisQ46050836
Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.Q52192889
Glycogen Synthase Kinase-3 from Rabbit Skeletal MuscleQ56456617
Insulin-like growth factor-I stimulates c-fos and c-jun transcription in PC12 cellsQ72877333
Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cellsQ77378921
Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanismQ77402826
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpositive regulation of protein kinase B signalingQ14761970
insulin receptorQ422579
Insulin like growth factor 2Q2006984
preproinsulinQ7240673
P304page(s)610-618
P577publication date2001-01-01
P1433published inJournal of Cellular BiochemistryQ6294917
P1476titleRegulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A
P478volume82

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cites work (P2860)
Q28304084A critical role for IGF-II in memory consolidation and enhancement.
Q36646199A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis
Q37709546Clear differences in cerebrospinal fluid proteome between women with chronic widespread pain and healthy women - a multivariate explorative cross-sectional study
Q91762067Core Element Cloning, Cis-Element Mapping and Serum Regulation of the Human EphB4 Promoter: A Novel TATA-Less Inr/MTE/DPE-Like Regulated Gene
Q33966144Differentiation of single cell derived human mesenchymal stem cells into cells with a neuronal phenotype: RNA and microRNA expression profile.
Q46240548IGF and insulin receptor signaling in breast cancer.
Q51765382Identification of Insulin Receptor Splice Variant B in Neurons by in situ Detection in Human Brain Samples.
Q91594882Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IRA axis in malignant mesothelioma
Q45041939Inhibition of phosphatidylinositol-3-kinase enhances insulin stimulation of insulin receptor substrate 1 tyrosine phosphorylation and extracellular signal-regulated kinases in mouse R- fibroblasts
Q38597801Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus
Q38780921Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.
Q38795736Molecular alterations in apoptotic pathways after PKB/Akt-mediated chemoresistance in NCI H460 cells
Q90296263Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling
Q89599170The IGF-II-Insulin Receptor Isoform-A Autocrine Signal in Cancer: Actionable Perspectives

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