Helicase structure and mechanism

scientific article

Helicase structure and mechanism is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0959-440X(02)00298-1
P3181OpenCitations bibliographic resource ID1681765
P698PubMed publication ID11839499

P2093author name stringDavid B McKay
Jonathan M Caruthers
P2860cites workCrystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicaseQ24539503
Helicases: amino acid sequence comparisons and structure-function relationshipsQ56657141
Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopyQ73103077
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding foldQ24556499
Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicaseQ24642694
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresQ26778412
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicasesQ27484152
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanismQ27617870
DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicaseQ27618867
Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae--the prototype of the DEAD box protein familyQ27619046
Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilusQ27619948
Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7Q27620078
Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicaseQ27620480
Crystal structure of Thermus thermophilus HB8 UvrB protein, a key enzyme of nucleotide excision repairQ27620507
Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repairQ27620746
Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotidesQ27625337
Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschiiQ27629461
Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010Q27629602
Structure and mechanism of the RuvB Holliday junction branch migration motorQ27633740
The structure of the E. coli recA protein monomer and polymerQ27643868
Structure of the recA protein–ADP complexQ27643870
Crystal structure of a DExx box DNA helicaseQ27733946
Structure of the hepatitis C virus RNA helicase domainQ27739123
Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADPQ27742867
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwindingQ27748908
Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNAQ27758298
Raster3D: photorealistic molecular graphicsQ27860557
The Pfam protein families database.Q27861012
Mechanical devices of the spliceosome: motors, clocks, springs, and thingsQ27938081
DExD/H box RNA helicases: from generic motors to specific dissociation functionsQ29615304
Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.Q33952351
Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicasesQ34387475
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.Q35116428
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicaseQ37098052
A two-site kinetic mechanism for ATP binding and hydrolysis by E. coli Rep helicase dimer bound to a single-stranded oligodeoxynucleotideQ38324775
Characterisation of Bacillus stearothermophilus PcrA helicase: evidence against an active rolling mechanismQ39723941
Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation.Q39728705
The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysisQ40656567
Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speedQ47249752
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectATP bindingQ14817981
Mov10 like RISC complex RNA helicase 1Q21119373
P304page(s)123-33
P577publication date2002-02-01
P1433published inCurrent Opinion in Structural BiologyQ15758416
P1476titleHelicase structure and mechanism
P478volume12

Reverse relations

cites work (P2860)
Q36791309A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex
Q42121359A SRS2 homolog from Arabidopsis thaliana disrupts recombinogenic DNA intermediates and facilitates single strand annealing
Q34931851A complex-based reconstruction of the Saccharomyces cerevisiae interactome
Q27931157A conserved Swi2/Snf2 ATPase motif couples ATP hydrolysis to chromatin remodeling
Q24338490A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex
Q39698916A model for dsDNA translocation revealed by a structural motif common to RecG and Mfd proteins
Q42421363A novel replicative enzyme encoded by the linear Arthrobacter plasmid pAL1.
Q57753824A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I
Q42151382A role for the cytoplasmic DEAD box helicase Dbp21E2 in rhodopsin maturation and photoreceptor viability
Q83538235A single amino acid in the helicase domain of PMMoV-S is responsible for its enhanced accumulation in C. chinense (L(3)L(3)) plants at 32°C
Q34103699A split active site couples cap recognition by Dcp2 to activation
Q33725394A superfamily 3 DNA helicase encoded by plasmid pSSVi from the hyperthermophilic archaeon Sulfolobus solfataricus unwinds DNA as a higher-order oligomer and interacts with host primase
Q48056420A vasa gene from green mud crab Scylla paramamosain and its expression during gonadal development and gametogenesis
Q36526389ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2)
Q24646651ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding
Q36005270ATP-dependent chromatin remodeling
Q27675185ATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA Translocase
Q46705698ATPase activity of RecD is essential for growth of the Antarctic Pseudomonas syringae Lz4W at low temperature
Q34810356ATPases as drug targets: learning from their structure
Q34365341Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A
Q37522958An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase
Q37135534Animal Mitochondrial DNA Replication.
Q37122013Application of a Euryarchaeota-Specific Helicase from Thermococcus kodakarensis for Noise Reduction in PCR.
Q27938034Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening
Q83222340Assaying DEAD-box RNA helicases and their role in mRNA degradation in Escherichia coli
Q36526232Asymmetric regulation of bipolar single-stranded DNA translocation by the two motors within Escherichia coli RecBCD helicase
Q27653490Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Q24309374Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor
Q34092871Brome mosaic virus 1a nucleoside triphosphatase/helicase domain plays crucial roles in recruiting RNA replication templates.
Q73268393Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability
Q36916655CHD proteins: a diverse family with strong ties
Q43198071Characterization of a thermostable UvrD helicase and its participation in helicase-dependent amplification
Q24791333Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifs
Q28487081Characterization of the helicase activity and substrate specificity of Mycobacterium tuberculosis UvrD
Q33720583Chloroplast- or Mitochondria-Targeted DEAD-Box RNA Helicases Play Essential Roles in Organellar RNA Metabolism and Abiotic Stress Responses
Q38830122Classification of pseudo pairs between nucleotide bases and amino acids by analysis of nucleotide-protein complexes
Q111346295Cloning and expression pattern of eukaryotic translation initiation factor 4A of the diamondback moth, Plutella xylostella
Q34387311Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of the N-terminal domain of DEAD-box RNA helicase from Staphylococcus aureus strain Mu50
Q36752413Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7.
Q44570241Complete nucleotide sequence of a new variant of grapevine rupestris stem pitting-associated virus from southern Italy
Q34353602Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis
Q27939616Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis
Q38202631Computational biology approach to uncover hepatitis C virus helicase operation
Q24293180Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF
Q29999792Conformational changes of a Swi2/Snf2 ATPase during its mechano-chemical cycle
Q42779890Controlling the motor activity of a transcription-repair coupling factor: autoinhibition and the role of RNA polymerase
Q27485425Coordinate Replication of Alfalfa Mosaic Virus RNAs 1 and 2 Involves cis - and trans -Acting Functions of the Encoded Helicase-Like and Polymerase-Like Domains
Q24810623Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence
Q34366536Crystal structure and functional analysis of DEAD-box protein Dhh1p
Q34331322Crystal structure of a Rad51 filament
Q27649153Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3
Q27642800Crystal structure of the BstDEAD N-terminal domain: a novel DEAD protein from Bacillus stearothermophilus
Q27641803Crystal structure of the SF3 helicase from adeno-associated virus type 2
Q38294458Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 A.
Q33581257Crystal structure of the human ATP-dependent splicing and export factor UAP56.
Q58618628Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP
Q33278262Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response
Q52720017DDX5 RNA Helicases: Emerging Roles in Viral Infection.
Q38208676DDX6 and its orthologs as modulators of cellular and viral RNA expression
Q26999638DEAD-box helicases as integrators of RNA, nucleotide and protein binding
Q29619863DEAD-box proteins: the driving forces behind RNA metabolism
Q41870184DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle
Q38097227DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication
Q34221058DExD/H-box proteins and their partners: helping RNA helicases unwind
Q47397800DISARM is a widespread bacterial defence system with broad anti-phage activities.
Q35064515DNA manipulators: caught in the act.
Q27022940DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy
Q34652749DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases
Q39215874DbpA is a region-specific RNA helicase
Q46493120De Novo Missense Mutations in DHX30 Impair Global Translation and Cause a Neurodevelopmental Disorder.
Q42019479Development and evaluation of a structural model for SF1B helicase Dda.
Q38861550Different proteomic strategies to identify genuine Small Ubiquitin-like MOdifier targets and their modification sites in Trypanosoma brucei procyclic forms
Q21145897Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity
Q27934397Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins
Q36742231Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.
Q57976550Disorder-order folding transitions underlie catalysis in the helicase motor of SecA
Q34658134Displacement of a DNA binding protein by Dda helicase
Q24309076Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome
Q40969310DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings
Q30336250Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.
Q38066334Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing
Q36315971Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly
Q35213825Dynamics of pre-replication complex proteins during the cell division cycle
Q35204590Energy use by biological protein transport pathways
Q27478372Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants
Q44608908Enzymatic mechanism of RNA translocation in double-stranded RNA bacteriophages
Q38357160Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme
Q37228485Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex
Q33784479Evidence in vivo that the DEAD-box RNA helicase RhlB facilitates the degradation of ribosome-free mRNA by RNase E
Q30435370Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase
Q62710214Extent of Single-stranded DNA Required for Efficient TraI Helicase Activityin Vitro
Q37903659From unwinding to clamping - the DEAD box RNA helicase family
Q41807822Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro
Q24701782Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity
Q44704139Functional mapping of PVX RNA-dependent RNA-replicase using pentapeptide scanning mutagenesis-Identification of regions essential for replication and subgenomic RNA amplification
Q44888122Functional properties of the herpes simplex virus type I origin-binding protein are controlled by precise interactions with the activated form of the origin of DNA replication
Q54536175Functionally significant mobile regions of Escherichia coli SecA ATPase identified by NMR.
Q45422939Genetic analysis of the function of the plum pox virus CI RNA helicase in virus movement
Q34507001Genome sequence and molecular characterization of Homalodisca coagulata virus-1, a novel virus discovered in the glassy-winged sharpshooter (Hemiptera: Cicadellidae).
Q24621899Genome-wide comprehensive analysis of human helicases
Q44790621Global co-ordination of protein translocation by the SecA IRA1 switch
Q40640148HPV E1 up-regulates replication-related biochemistries of AAV Rep78.
Q45376581Helicase ATPase activity of the Tobacco mosaic virus 126-kDa protein modulates replicase complex assembly
Q43046851Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling.
Q40104144Helicase Motif III in SecA is essential for coupling preprotein binding to translocation ATPase.
Q34471081Helicase motif Ia is involved in single-strand DNA-binding and helicase activities of the herpes simplex virus type 1 origin-binding protein, UL9.
Q24533521Helicase-dependent isothermal DNA amplification
Q41933191Helicase-dependent isothermal amplification: a novel tool in the development of molecular-based analytical systems for rapid pathogen detection.
Q91906005Helicases as molecular motors: An insight
Q35651729Hepatitis C. Development of new drugs and clinical trials: promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February 27-March 1, 2003.
Q27642248High-resolution structure of the E.coli RecQ helicase catalytic core
Q36548179Host restriction factors in retroviral infection: promises in virus-host interaction
Q30480704How directional translocation is regulated in a DNA helicase motor
Q27675671Human Suv3 protein reveals unique features among SF2 helicases
Q42011517Identification and characterization of RNA duplex unwinding and ATPase activities of an alphatetravirus superfamily 1 helicase.
Q36154642Identification and characterization of an isolate of apple green crinkle associated virus involved in a severe disease of quince (Cydonia oblonga, Mill.).
Q33276952Identification and characterization of bovine regulator of telomere length elongation helicase gene (RTEL): molecular cloning, expression distribution, splice variants and DNA methylation profile
Q42164702Identification and in silico analysis of cattle DExH/D box RNA helicases
Q35668775Identification of molecular determinants from Moloney leukemia virus 10 homolog (MOV10) protein for virion packaging and anti-HIV-1 activity.
Q41216402Identification of small-molecule inhibitors against SecA by structure-based virtual ligand screening
Q42485674Identification of the preprotein binding domain of SecA.
Q27333608In silico investigation of conformational motions in superfamily 2 helicase proteins
Q34631076Inhibition of an iron-responsive element/iron regulatory protein-1 complex by ATP binding and hydrolysis
Q35130867Interaction of Escherichia coli DbpA with 23S rRNA in different functional states of the enzyme
Q36868446Interactions between branched DNAs and peptide inhibitors of DNA repair
Q35779031Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.
Q27926249Intrinsically Disordered Side of the Zika Virus Proteome
Q34246661Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
Q43027686Knockout and functional analysis of two DExD/H-box family helicase genes in Sulfolobus islandicus REY15A.
Q46825942Leishmania infantum LeIF protein is an ATP-dependent RNA helicase and an eIF4A-like factor that inhibits translation in yeast
Q42006060Lethal action of quinolones against a temperature-sensitive dnaB replication mutant of Escherichia coli.
Q40714764Ligand-induced conformation changes drive ATP hydrolysis and function in SMARCAL1.
Q47446718Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A.
Q34456088MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells
Q27933744Mak5p, which is required for the maintenance of the M1 dsRNA virus, is encoded by the yeast ORF YBR142w and is involved in the biogenesis of the 60S subunit of the ribosome
Q54551685Mechanical transduction mechanisms of RecA-like molecular motors.
Q27652992Mechanism of ATP turnover inhibition in the EJC
Q42983047Mechanism of flexibility control for ATP access of hepatitis C virus NS3 helicase
Q36578943Mechanisms of a ring shaped helicase
Q100490995Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters
Q45535794Modeling the helicase domain of Brome mosaic virus 1a replicase
Q24648359Modular architecture of the hexameric human mitochondrial DNA helicase
Q34181409Molecular Basis for Recognition of Nucleoside Triphosphate by Gene 4 Helicase of Bacteriophage T7
Q38093446Molecular and cellular pathogenesis of melanoma initiation and progression.
Q43938239Molecular characterization of a new Tospovirus infecting soybean
Q97905013Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd
Q41895411Molecular dynamics simulations of a helicase
Q33825197Moloney leukemia virus 10 (MOV10) protein inhibits retrovirus replication
Q40883770Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase
Q36471439Mutation of the arginine finger in the active site of Escherichia coli DbpA abolishes ATPase and helicase activity and confers a dominant slow growth phenotype
Q24541400Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay
Q35759551Mutational analysis of the Escherichia coli DEAD box protein CsdA
Q27491297NSs Encoded by Groundnut Bud Necrosis Virus Is a Bifunctional Enzyme
Q36261377Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication
Q43037770Nucleic acid unwinding by hepatitis C virus and bacteriophage t7 helicases is sensitive to base pair stability
Q60489240Nucleosome remodeling
Q27639672Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA
Q36608490Oligomeric states of the SecA and SecYEG core components of the bacterial Sec translocon
Q39732614Oligomerization and activity of the helicase domain of the tobacco mosaic virus 126- and 183-kilodalton replicase proteins
Q40552534Oligomerization of Ebola virus VP30 is essential for viral transcription and can be inhibited by a synthetic peptide
Q30425105One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes?
Q36700546OsBIRH1, a DEAD-box RNA helicase with functions in modulating defence responses against pathogen infection and oxidative stress
Q36827289Packaging motor from double-stranded RNA bacteriophage phi12 acts as an obligatory passive conduit during transcription.
Q28469302Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032
Q38216121Parts, assembly and operation of the RIG-I family of motors
Q42986507Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase
Q54535975Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA.
Q42732957Phylogenetic distribution and evolutionary history of bacterial DEAD-Box proteins
Q35851875Physical analysis of recombinant forms of the human mitochondrial DNA helicase
Q37353966Physiology and genetics of Listeria monocytogenes survival and growth at cold temperatures
Q61792042Plasmodium falciparum specific helicase 2 is a dual, bipolar helicase and is crucial for parasite growth
Q42377173Plasmodium falciparum specific helicase 3 is nucleocytoplasmic protein and unwinds DNA duplex in 3' to 5' direction
Q24670723Preprotein-controlled catalysis in the helicase motor of SecA
Q28357054Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile
Q27662061Prp43p contains a processive helicase structural architecture with a specific regulatory domain
Q24535910Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
Q43103139Purification strategy for recombinant forms of the human mitochondrial DNA helicase
Q47236714RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions
Q31042190RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells
Q27654400RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon
Q36514468RNA helicases and abiotic stress.
Q64387294Rad54 Phosphorylation Promotes Homologous Recombination by Balancing Rad54 Mobility and DNA Binding
Q55437951RecA-like domain 2 of DNA-dependent ATPase A domain, a SWI2/SNF2 protein, mediates conformational integrity and ATP hydrolysis.
Q24537705Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.
Q24338327Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
Q24310270Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2
Q44187652Replication of cucumber mosaic virus RNA 1 in cis requires functional helicase-like motifs of the 1a protein
Q33940331Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex
Q51204003Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA.
Q42467631Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2.
Q27477537Role of RNA helicases in HIV-1 replication
Q58018244Second report on chicken genes and chromosomes 2005
Q33554200Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding
Q35132443Sexually dimorphic expression of vasa isoforms in the tongue sole (Cynoglossus semilaevis).
Q35100587Sit down, relax and unwind: structural insights into RecQ helicase mechanisms
Q36578937Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures
Q90444286Soybean vein necrosis virus: an emerging virus in North America
Q92253163SrmB Rescues Trapped Ribosome Assembly Intermediates
Q97885504Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation
Q42689212Structural and functional characterization of the human DNA repair helicase XPD by comparative molecular modeling and site-directed mutagenesis of the bacterial repair protein UvrB.
Q43037798Structural and functional comparison of the non-structural protein 4B in flaviviridae
Q27640680Structural and functional insights into the human Upf1 helicase core
Q27656314Structural and functional studies of the yeast class II Hda1 histone deacetylase complex
Q37546176Structural aspects of RNA helicases in eukaryotic mRNA decay
Q27649210Structural basis of mechanochemical coupling in a hexameric molecular motor
Q27655950Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
Q42594464Structural features of Chi recognition in AddAB with implications for RecBCD.
Q37223884Structural frameworks for considering microbial protein- and nucleic acid-dependent motor ATPases
Q42328217Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
Q42613420Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2.
Q42921287Structure and Mechanisms of SF1 DNA Helicases
Q24321366Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response
Q35817571Structure and function of RecQ DNA helicases
Q23011530Structure and functionality in flavivirus NS-proteins: perspectives for drug design
Q35758805Structure and mechanism of the RNA polymerase II transcription machinery
Q27652104Structure of RapA, a Swi2/Snf2 Protein that Recycles RNA Polymerase During Transcription
Q27470453Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A
Q27470433Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing
Q27663709Structure of the RNA Binding Domain of a DEAD-Box Helicase Bound to Its Ribosomal RNA Target Reveals a Novel Mode of Recognition by an RNA Recognition Motif
Q28243168Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54
Q36426537Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN.
Q36522085Structure, function and evolution of the animal mitochondrial replicative DNA helicase.
Q28768048Structure-based model of the stepping motor of PcrA helicase
Q42992194Structure-based virtual screening for novel inhibitors of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase
Q50620442Subcellular localization of the triple gene block proteins encoded by a Foveavirus infecting grapevines.
Q41872949Synergistic effects of ATP and RNA binding to human DEAD-box protein DDX1.
Q35966770The ATP-dependent RNA helicase HrpB plays an important role in motility and biofilm formation in Xanthomonas citri subsp. citri
Q30799661The ATPases: a new family for a family-based drug design approach
Q47402031The DEAD-box RNA Helicase RH50 Is a 23S-4.5S rRNA Maturation Factor that Functionally Overlaps with the Plastid Signaling Factor GUN1.
Q57259006The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases
Q36566603The DbpA catalytic core unwinds double-helix substrates by directly loading on them
Q52374636The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.
Q27672895The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1
Q33963813The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis
Q44153079The RNA helicase DbpA exhibits a markedly different conformation in the ADP-bound state when compared with the ATP- or RNA-bound states
Q40524485The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core.
Q27934054The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes
Q33598282The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans
Q44235307The carboxy-terminal domain of the DExDH protein YxiN is sufficient to confer specificity for 23S rRNA.
Q60921857The conformational changes coupling ATP hydrolysis and translocation in a bacterial DnaB helicase
Q38341790The conformational plasticity of eukaryotic RNA-dependent ATPases
Q24332542The crystal structure of Zika virus helicase: basis for antiviral drug design
Q34625723The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold
Q30444766The domain structure of Helicobacter pylori DnaB helicase: the N-terminal domain can be dispensable for helicase activity whereas the extreme C-terminal region is essential for its function
Q37624407The emerging roles of the DDX41 protein in immunity and diseases
Q28272982The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity
Q54346226The function of RH22, a DEAD RNA helicase, in the biogenesis of the 50S ribosomal subunits of Arabidopsis chloroplasts.
Q42620165The genome and proteome of coliphage T1.
Q39384751The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.
Q43024714The mycobacterial PhoH2 proteins are type II toxin antitoxins coupled to RNA helicase domains.
Q34327481The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity
Q42017648The non-structural protein NS-2 of Bombyx mori parvo-like virus is localized to the nuclear membrane
Q45396994The requirement of the DEAD-box protein DDX24 for the packaging of human immunodeficiency virus type 1 RNA.
Q40568559The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.
Q57756314The study of interactions between DNA and PcrA DNA helicase by using targeted molecular dynamic simulations
Q34600531The two eIF4A helicases in Trypanosoma brucei are functionally distinct.
Q45005887The zinc finger motif of Escherichia coli RecQ is implicated in both DNA binding and protein folding.
Q30356850Three dimensional model of severe acute respiratory syndrome coronavirus helicase ATPase catalytic domain and molecular design of severe acute respiratory syndrome coronavirus helicase inhibitors.
Q38185572To peep into Pif1 helicase: multifaceted all the way from genome stability to repair-associated DNA synthesis
Q44317704Transient kinetic analysis of ATP-induced allosteric transitions in the eukaryotic chaperonin containing TCP-1.
Q35991471Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements.
Q43018165Ultraviolet-radiation-resistant isolates revealed cellulose-degrading species of Cellulosimicrobium cellulans (UVP1) and Bacillus pumilus (UVP4).
Q34056764Unique helicase determinants in the essential conjugative TraI factor from Salmonella enterica serovar Typhimurium plasmid pCU1.
Q22065679Unraveling DNA helicases. Motif, structure, mechanism and function
Q36483339Unraveling the 'DEAD-box' helicases of Plasmodium falciparum
Q38332906Unzippers, resolvers and sensors: a structural and functional biochemistry tale of RNA helicases
Q33344714Use of synthetic signal sequences to explore the protein export machinery
Q36267887Viral and cellular RNA helicases as antiviral targets
Q46665831YxiN is a modular protein combining a DEx(D/H) core and a specific RNA-binding domain
Q37856199mRNA helicases: the tacticians of translational control

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