| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2007PNAS..104..582S |
| P356 | DOI | 10.1073/PNAS.0606699104 |
| P8608 | Fatcat ID | release_c7ecn6blhfhzpptyxlpxlw75bi |
| P3181 | OpenCitations bibliographic resource ID | 760932 |
| P932 | PMC publication ID | 1766428 |
| P698 | PubMed publication ID | 17190814 |
| P5875 | ResearchGate publication ID | 6609398 |
| P50 | author | Shizuo Akira | Q2279629 |
| Michael Gale | Q38328848 | ||
| David M. Owen | Q55189280 | ||
| P2093 | author name string | Cynthia L Johnson | |
| Reiko Hirai | |||
| Sangita C Sinha | |||
| Takashi Fujita | |||
| Takeshi Saito | |||
| Yueh-Ming Loo | |||
| P2860 | cites work | Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB | Q22010046 |
| Helicase structure and mechanism | Q24292281 | ||
| IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction | Q24318426 | ||
| mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties | Q24530264 | ||
| Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection | Q24546318 | ||
| Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I | Q24556673 | ||
| RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2 | Q24673649 | ||
| Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication | Q27472912 | ||
| Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses: Implications for virus evolution and host persistence | Q27472977 | ||
| Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses | Q27860455 | ||
| The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses | Q27860685 | ||
| Production of infectious hepatitis C virus in tissue culture from a cloned viral genome | Q27860899 | ||
| RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates | Q27861007 | ||
| 5'-Triphosphate RNA is the ligand for RIG-I | Q28131726 | ||
| WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation | Q28290389 | ||
| The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue | Q28588610 | ||
| Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling | Q29614206 | ||
| Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease | Q29614208 | ||
| Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus | Q29615029 | ||
| Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity | Q29615913 | ||
| Cell type-specific involvement of RIG-I in antiviral response | Q29615914 | ||
| The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. | Q34457606 | ||
| Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection | Q36402851 | ||
| Intracellular pattern recognition receptors in the host response | Q36528528 | ||
| An infectious molecular clone of a Japanese genotype 1b hepatitis C virus | Q42604623 | ||
| CARD games between virus and host get a new player | Q45422197 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 582-7 | |
| P577 | publication date | 2007-01-09 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2 | |
| P478 | volume | 104 |
| Q35860633 | 5'-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity |
| Q35639613 | A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance |
| Q51336602 | A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time. |
| Q38977716 | A Novel Mechanism Underlying the Innate Immune Response Induction upon Viral-Dependent Replication of Host Cell mRNA: A Mistake of +sRNA Viruses' Replicases |
| Q34049284 | A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells |
| Q34945431 | A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses |
| Q38857831 | A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response |
| Q24306232 | A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection |
| Q89601086 | A rare form of dermatomyositis associated with muscle weakness and normal creatine kinase level |
| Q24320094 | A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2 |
| Q46241883 | A single amino acid substitution within the Paramyxovirus Sendai virus nucleoprotein is a critical determinant for production of IFN-beta-inducing copyback-type defective interfering genomes |
| Q34464259 | A structure-based model of RIG-I activation |
| Q33917851 | A time-resolved molecular map of the macrophage response to VSV infection |
| Q43042364 | A wide range of NS3/4A protease catalytic efficiencies in HCV-infected individuals |
| Q34695889 | ARF-like protein 16 (ARL16) inhibits RIG-I by binding with its C-terminal domain in a GTP-dependent manner |
| Q36526389 | ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2) |
| Q35606341 | Activation and evasion of antiviral innate immunity by hepatitis C virus. |
| Q35783875 | Activation of RIG-I-like receptor signal transduction |
| Q37510744 | Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin |
| Q37033361 | Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cells |
| Q27487543 | Agonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity Receptor |
| Q36948514 | Altered innate immunity in chronic hepatitis C infection: cause or effect? |
| Q38656528 | Alternative Pre-mRNA Splicing in Mammals and Teleost Fish: A Effective Strategy for the Regulation of Immune Responses Against Pathogen Infection |
| Q47371034 | Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response |
| Q28546870 | An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction |
| Q36241494 | An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp |
| Q35259962 | Antagonism of innate immunity by paramyxovirus accessory proteins |
| Q38976634 | Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5. |
| Q38235759 | Antiviral RNA recognition and assembly by RLR family innate immune sensors |
| Q27489800 | Antiviral activity and host gene induction by tamarin and marmoset interferon-α and interferon-γ in the GBV-B primary hepatocyte culture model |
| Q30358265 | Antiviral activity of baicalin against influenza virus H1N1-pdm09 is due to modulation of NS1-mediated cellular innate immune responses. |
| Q59349462 | Camouflage and interception: How pathogens evade detection by intracellular nucleic acid sensors |
| Q39631969 | Cardiac glycosides are potent inhibitors of interferon-β gene expression |
| Q24298724 | Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I |
| Q38090473 | Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses |
| Q90505652 | Cell-type specificity and functional redundancy of RIG-I-like receptors in innate immune sensing of Coxsackievirus B3 and encephalomyocarditis virus |
| Q38051306 | Challenge models to assess new therapies in chronic obstructive pulmonary disease |
| Q40784450 | Characterization and immune response expression of the Rig-I-like receptor mda5 in common carp Cyprinus carpio |
| Q34874614 | Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors |
| Q40081933 | Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates |
| Q38990872 | Cloning and expression of retinoic acid-induced gene-I and its effect on hepatitis C virus replication |
| Q66679118 | Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5 |
| Q93207268 | Comparative characterization of flavivirus production in two cell lines: Human hepatoma-derived Huh7.5.1-8 and African green monkey kidney-derived Vero |
| Q34323065 | Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly |
| Q39413432 | Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix α0. |
| Q36364287 | Control of the induction of type I interferon by Peste des petits ruminants virus |
| Q39437743 | Conventional protein kinase C-α (PKC-α) and PKC-β negatively regulate RIG-I antiviral signal transduction |
| Q35641310 | Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition |
| Q51712590 | Critical role of RIG-I-like receptors in inflammation in chronic obstructive pulmonary disease. |
| Q34295304 | Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity |
| Q27684911 | Crystal and solution structure of the human RIG-I SF2 domain |
| Q27649959 | Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain |
| Q27679898 | Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling |
| Q38494599 | Crystallization and preliminary crystallographic studies of human RIG-I in complex with double-stranded RNA. |
| Q39195781 | Cytosolic nucleic acid sensors and innate immune regulation |
| Q39899310 | Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA. |
| Q24317028 | DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling |
| Q24298235 | DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential |
| Q26796544 | DED or alive: assembly and regulation of the death effector domain complexes |
| Q38097227 | DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication |
| Q28075204 | Danger Signals and Graft-versus-host Disease: Current Understanding and Future Perspectives |
| Q44885753 | Deciphering interactions used by the influenza virus NS1 protein to silence the host antiviral sensor protein RIG-I using a bacterial reverse two-hybrid system |
| Q49906730 | Defective RNA sensing by RIG-I in severe influenza virus infection. |
| Q39180416 | Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling |
| Q37426836 | Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation |
| Q36742231 | Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity. |
| Q40213813 | Discrimination of Self and Non-Self Ribonucleic Acids |
| Q27485306 | Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity |
| Q42429796 | Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis |
| Q39611535 | Duck RIG-I CARD Domain Induces the Chicken IFN-β by Activating NF-κB. |
| Q35602911 | EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway |
| Q28074848 | Emerging Roles of Protein Deamidation in Innate Immune Signaling |
| Q38495929 | Emerging complexity and new roles for the RIG-I-like receptors in innate antiviral immunity |
| Q34057885 | Enhancement of interferon induction by ORF3 product of hepatitis E virus |
| Q37704544 | Enter at your own risk: how enteroviruses navigate the dangerous world of pattern recognition receptor signaling |
| Q54249868 | Enteric Virome Sensing-Its Role in Intestinal Homeostasis and Immunity. |
| Q39255043 | Essential role of RIG-I in the activation of endothelial cells by dengue virus |
| Q40014093 | Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity |
| Q27485316 | Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1 |
| Q35867232 | Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue |
| Q37721842 | Exposing viruses: RNA patterns sensed by RIG-I-like receptors |
| Q35140360 | Expression and functional characterization of the RIG-I-like receptors MDA5 and LGP2 in Rainbow trout (Oncorhynchus mykiss). |
| Q112639850 | Flavivirus Capsid Proteins Inhibit the Interferon Response |
| Q61448766 | Frog Skin Innate Immune Defences: Sensing and Surviving Pathogens |
| Q24632537 | Function and regulation of retinoic acid-inducible gene-I |
| Q36774929 | Function of RIG-I-like receptors in antiviral innate immunity |
| Q57753018 | Functional Evolution of Avian RIG-I-Like Receptors |
| Q40173025 | Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense |
| Q34364612 | Functional characterizations of RIG-I to GCRV and viral/bacterial PAMPs in grass carp Ctenopharyngodon idella |
| Q35190533 | Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity |
| Q27488345 | Gene expression and hepatitis C virus infection |
| Q37118371 | Genetic architecture of transcript-level variation in humans |
| Q38522796 | Genetic variation in pattern recognition receptors: functional consequences and susceptibility to infectious disease. |
| Q41921212 | Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses |
| Q87800944 | Grass Carp Laboratory of Genetics and Physiology 2 Serves As a Negative Regulator in Retinoic Acid-Inducible Gene I- and Melanoma Differentiation-Associated Gene 5-Mediated Antiviral Signaling in Resting State and Early Stage of Grass Carp Reovirus |
| Q28475559 | Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I |
| Q36584342 | HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I. |
| Q55508841 | Harnessing RIG-I and intrinsic immunity in the tumor microenvironment for therapeutic cancer treatment. |
| Q33694809 | Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system |
| Q38077029 | Helicase-mediated changes in RNA structure at the single-molecule level. |
| Q38593783 | Helicases in Antiviral Immunity: Dual Properties as Sensors and Effectors |
| Q92191568 | Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection |
| Q41761723 | Hepatitis C Virus Evasion from RIG-I-Dependent Hepatic Innate Immunity |
| Q27485023 | Hepatitis C Virus Infection Induces the Beta Interferon Signaling Pathway in Immortalized Human Hepatocytes |
| Q90167787 | Hepatitis C Virus Infection Is Inhibited by a Noncanonical Antiviral Signaling Pathway Targeted by NS3-NS4A |
| Q35604054 | Hepatitis C Virus. Strategies to Evade Antiviral Responses |
| Q27487394 | Hepatitis C and Innate Immunity: Recent Advances |
| Q35270150 | Hepatitis C virus and antiviral innate immunity: who wins at tug-of-war? |
| Q33775699 | Hepatitis C virus core protein abrogates the DDX3 function that enhances IPS-1-mediated IFN-beta induction |
| Q40099643 | Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy |
| Q36244165 | Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2. |
| Q37772959 | Hepatitis C: viral and host factors associated with non-response to pegylated interferon plus ribavirin. |
| Q39092892 | Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity |
| Q38163544 | Host-Viral Interactions: Role of Pattern Recognition Receptors (PRRs) in Human Pneumovirus Infections |
| Q41992231 | Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence. |
| Q40291697 | Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors. |
| Q35913195 | IFN-β-inducing, unusual viral RNA species produced by paramyxovirus infection accumulated into distinct cytoplasmic structures in an RNA-type-dependent manner |
| Q27490889 | IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity |
| Q34539832 | IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling |
| Q41682677 | Identification and expression of the laboratory of genetics and physiology 2 gene in common carp Cyprinus carpio |
| Q39867703 | Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes |
| Q37069062 | Identification of multiple RIG-I-specific pathogen associated molecular patterns within the West Nile virus genome and antigenome |
| Q26746467 | Immune Activation in the Liver by Nucleic Acids |
| Q26782040 | Immune and non-immune responses to hepatitis C virus infection |
| Q24304438 | Immune signaling by RIG-I-like receptors |
| Q37534555 | Immune-Related Gene Expression Patterns in GPV- or H9N2-Infected Goose Spleens |
| Q34022013 | Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant |
| Q33886433 | Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein |
| Q38391949 | Importance of interferon inducible trans-membrane proteins and retinoic acid inducible gene I for influenza virus replication: A review |
| Q35152238 | In vivo ligands of MDA5 and RIG-I in measles virus-infected cells |
| Q33915111 | Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling |
| Q38161258 | Induction and control of the type I interferon pathway by Bluetongue virus |
| Q34003764 | Induction and evasion of innate antiviral responses by hepatitis C virus |
| Q37949459 | Induction and evasion of type I interferon responses by influenza viruses |
| Q38236277 | Induction and suppression of innate antiviral responses by picornaviruses |
| Q29042349 | Induction of type I interferon by RNA viruses: cellular receptors and their substrates |
| Q28088483 | Influenza virus activation of the interferon system |
| Q64229581 | Innate Immune Responses to Avian Influenza Viruses in Ducks and Chickens |
| Q38170229 | Innate antiviral immune signaling, viral evasion and modulation by HIV-1. |
| Q27489865 | Innate immune evasion by hepatitis C virus and West Nile virus |
| Q35868815 | Innate immune recognition of nucleic acids |
| Q33805229 | Innate immune recognition of viruses and viral vectors |
| Q37997024 | Innate immunity and hepatitis C virus infection: a microarray's view |
| Q24634416 | Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA |
| Q40312347 | Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5. |
| Q37361448 | Innate immunity to virus infection. |
| Q26996036 | Innate receptors and cellular defense against pulmonary infections |
| Q35108113 | Insight into buffalo (Bubalus bubalis) RIG1 and MDA5 receptors: a comparative study on dsRNA recognition and in-vitro antiviral response |
| Q92028460 | Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets |
| Q26860007 | Interferon induction by RNA viruses and antagonism by viral pathogens |
| Q45397719 | Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients |
| Q34212787 | Interplay between innate immunity and negative-strand RNA viruses: towards a rational model |
| Q37374825 | Intracellular detection of viral nucleic acids. |
| Q34319249 | Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens |
| Q34208090 | Intracellular innate immune cascades and interferon defenses that control hepatitis C virus |
| Q37627133 | Intracellular pathogen detection by RIG-I-like receptors |
| Q36185808 | Invertebrate Iridescent Virus 6, a DNA Virus, Stimulates a Mammalian Innate Immune Response through RIG-I-Like Receptors |
| Q36155506 | Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses |
| Q35716846 | Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5 |
| Q90068213 | Know Thyself: RIG-I-Like Receptor Sensing of DNA Virus Infection |
| Q39307499 | LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3. |
| Q24645870 | LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses |
| Q28084011 | LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling |
| Q91678692 | LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection |
| Q59358209 | LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs |
| Q33667898 | LGP2: positive about viral sensing |
| Q49755954 | Lab-Attenuated Rabies Virus Causes Abortive Infection and Induces Cytokine Expression in Astrocytes by Activating Mitochondrial Antiviral-Signaling Protein Signaling Pathway. |
| Q40370749 | Laboratory of genetics and physiology 2 (LGP2) plays an essential role in hepatitis C virus infection-induced interferon responses |
| Q24648192 | Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 |
| Q37304959 | Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew |
| Q37051657 | MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease |
| Q37145207 | MAVS self-association mediates antiviral innate immune signaling |
| Q27010611 | MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction |
| Q27677137 | MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA |
| Q24316163 | MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling |
| Q34708584 | MDA5 plays a crucial role in enterovirus 71 RNA-mediated IRF3 activation |
| Q38125018 | Master sensors of pathogenic RNA - RIG-I like receptors |
| Q37726746 | Measure and countermeasure: type I IFN (IFN-alpha/beta) antiviral response against West Nile virus |
| Q39914626 | Mechanism of mda-5 Inhibition by paramyxovirus V proteins. |
| Q35886583 | Mechanisms and pathways of innate immune activation and regulation in health and cancer |
| Q36035399 | Mechanisms of MAVS regulation at the mitochondrial membrane |
| Q27490827 | Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo |
| Q37522841 | Melanoma differentiation-associated gene 5 in zebrafish provoking higher interferon-promoter activity through signalling enhancing of its shorter splicing variant |
| Q44614118 | Melanoma differentiation-associated protein-5 (MDA-5) limits early viral replication but is not essential for the induction of type 1 interferons after Coxsackievirus infection |
| Q35913071 | Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate |
| Q37257891 | Methylcrotonoyl-CoA carboxylase 1 potentiates RLR-induced NF-κB signaling by targeting MAVS complex |
| Q39099480 | Microbial recognition and danger signals in sepsis and trauma |
| Q38258737 | Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors |
| Q37784872 | Mitochondria and viruses |
| Q37714034 | Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling |
| Q41107347 | Modeling and analysis of innate immune responses induced by the host cells against hepatitis C virus infection |
| Q38706585 | Molecular cloning of MDA5, phylogenetic analysis of RIG-I-like receptors (RLRs) and differential gene expression of RLRs, interferons and proinflammatory cytokines after in vitro challenge with IPNV, ISAV and SAV in the salmonid cell line TO. |
| Q38759960 | Molecular cloning, characterization and expression analysis of woodchuck retinoic acid-inducible gene I. |
| Q34253570 | Molecular mechanisms of viral inhibitors of RIG-I-like receptors |
| Q35751132 | Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE. |
| Q38041927 | Multi-level regulation of cellular recognition of viral dsRNA. |
| Q38918325 | Muscovy duck retinoic acid-induced gene I (MdRIG-I) functions in innate immunity against H9N2 avian influenza viruses (AIV) infections |
| Q35309808 | Myositis-specific autoantibodies: detection and clinical associations |
| Q28387246 | NLRs, inflammasomes, and viral infection |
| Q37860087 | Natural killer cell activation secondary to innate pattern sensing |
| Q36424059 | Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation |
| Q24324134 | Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3 |
| Q28116012 | Negative regulation of RIG-I-mediated innate antiviral signaling by SEC14L1 |
| Q27487296 | Negative regulation of cytoplasmic RNA-mediated antiviral signaling |
| Q39922463 | Negative regulation of virus-triggered IFN-beta signaling pathway by alternative splicing of TBK1. |
| Q39179381 | Negative regulators of the RIG-I-like receptor signaling pathway |
| Q33924436 | Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production |
| Q38120958 | Newly described pattern recognition receptors team up against intracellular pathogens |
| Q40097576 | Non-encapsidated 5' copy-back defective-interfering genomes produced by recombinant measles viruses are recognized by RIG-I and LGP2 but not MDA5. |
| Q39654502 | Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virus |
| Q27488308 | Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities |
| Q34896257 | Occurrence of genetic modifications in core, 5'UTR and NS5b of HCV associated with viral response to treatment |
| Q38827613 | Organ system view of the hepatic innate immunity in HCV infection |
| Q33436036 | Origin and evolution of the RIG-I like RNA helicase gene family |
| Q41285425 | Overexpression of feline tripartite motif-containing 25 interferes with the late stage of feline leukemia virus replication |
| Q40100614 | PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. |
| Q38994892 | Paramyxovirus V protein interaction with the antiviral sensor LGP2 disrupts MDA5 signaling enhancement but is not relevant to LGP2-mediated RLR signaling inhibition |
| Q24617419 | Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction |
| Q38156883 | Paramyxovirus evasion of innate immunity: Diverse strategies for common targets |
| Q21296719 | Pathogen recognition and activation of the innate immune response in zebrafish |
| Q24643034 | Pathogen recognition and inflammatory signaling in innate immune defenses |
| Q29615592 | Pathogen recognition by the innate immune system |
| Q36208105 | Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length |
| Q64084948 | Pattern Recognition by Melanoma Differentiation-Associated Gene 5 (Mda5) in Teleost Fish: A Review |
| Q37785794 | Pattern recognition of viral nucleic acids by RIG-I-like helicases |
| Q40237307 | Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system |
| Q34485161 | Phosphorylation of RIG-I by casein kinase II inhibits its antiviral response. |
| Q39609052 | Phosphorylation-mediated negative regulation of RIG-I antiviral activity |
| Q35895344 | Pigeon RIG-I Function in Innate Immunity against H9N2 IAV and IBDV |
| Q39834740 | Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS. |
| Q57092483 | Porcine Deltacoronavirus Accessory Protein NS6 Antagonizes Interferon Beta Production by Interfering with the Binding of RIG-I/MDA5 to Double-Stranded RNA |
| Q64259883 | Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination |
| Q84315450 | Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I |
| Q35060758 | Positive evolutionary selection on the RIG-I-like receptor genes in mammals |
| Q34136483 | Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing |
| Q39036428 | Protect this house: cytosolic sensing of viruses |
| Q42239259 | Protective role of LGP2 in influenza virus pathogenesis. |
| Q28543776 | Proteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking |
| Q36611248 | Pyruvate Carboxylase Activates the RIG-I-like Receptor-Mediated Antiviral Immune Response by Targeting the MAVS signalosome |
| Q55435928 | RIG-I Detects Kaposi's Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner. |
| Q36086242 | RIG-I Mediates an Antiviral Response to Crimean-Congo Hemorrhagic Fever Virus |
| Q33396469 | RIG-I and dsRNA-induced IFNbeta activation |
| Q28081618 | RIG-I in RNA virus recognition |
| Q37939129 | RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity. |
| Q37945229 | RIG-I like receptors in antiviral immunity and therapeutic applications |
| Q35279959 | RIG-I self-oligomerization is either dispensable or very transient for signal transduction |
| Q41684042 | RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome |
| Q107547969 | RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses |
| Q37543955 | RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation. |
| Q92602380 | RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection |
| Q24321688 | RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium |
| Q39358994 | RIG-I: a multifunctional protein beyond a pattern recognition receptor |
| Q34281605 | RNA helicases in infection and disease |
| Q52691333 | RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling. |
| Q34210374 | RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. |
| Q39090397 | Reciprocal inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells |
| Q37671348 | Recognition of viruses by cytoplasmic sensors |
| Q38054048 | Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses |
| Q47550753 | Regulation of RIG-I Activation by K63-Linked Polyubiquitination |
| Q38229327 | Regulation of RIG-I-like receptor signaling by host and viral proteins |
| Q26700093 | Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6 |
| Q34659642 | Regulation of adaptive immunity by the innate immune system |
| Q91826761 | Regulation of cGAS- and RLR-mediated immunity to nucleic acids |
| Q26824743 | Regulation of hepatic innate immunity by hepatitis C virus |
| Q45399186 | Regulation of innate immunity against hepatitis C virus infection. |
| Q24310270 | Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2 |
| Q90670400 | Regulation of virus-triggered type I interferon signaling by cellular and viral proteins |
| Q24611792 | Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific microRNA 122 |
| Q36185915 | Resurrecting ancestral structural dynamics of an antiviral immune receptor: adaptive binding pocket reorganization repeatedly shifts RNA preference. |
| Q36922870 | Retinoic acid inducible gene-I, more than a virus sensor |
| Q24315899 | Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection |
| Q37907346 | Role of Toll-like receptors in liver health and disease |
| Q34864608 | Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction |
| Q38338295 | SUMOylation of RIG-I positively regulates the type I interferon signaling |
| Q33554200 | Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding |
| Q37976964 | Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion |
| Q35163321 | Sensing of viral nucleic acids by RIG-I: from translocation to translation |
| Q37549926 | Sensors of the innate immune system: their mode of action |
| Q40180990 | Small self-RNA generated by RNase L amplifies antiviral innate immunity |
| Q24317636 | Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors |
| Q27675052 | Structural Insights into RNA Recognition by RIG-I |
| Q42771951 | Structural and biochemical studies of RIG-I antiviral signaling. |
| Q27674465 | Structural basis of RNA recognition and activation by innate immune receptor RIG-I |
| Q38056521 | Structural basis of innate immune recognition of viral RNA. |
| Q27674485 | Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation |
| Q24321366 | Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response |
| Q28471590 | Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response |
| Q38998010 | Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5. |
| Q33531803 | TRAF5 is a downstream target of MAVS in antiviral innate immune signaling |
| Q95271914 | Targeted Knockout of MDA5 and TLR3 in the DF-1 Chicken Fibroblast Cell Line Impairs Innate Immune Response Against RNA Ligands |
| Q99594459 | Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study |
| Q102210856 | Targeting nuclear acid-mediated immunity in cancer immune checkpoint inhibitor therapies |
| Q64272347 | The 14-3-3η chaperone protein promotes antiviral innate immunity via facilitating MDA5 oligomerization and intracellular redistribution |
| Q24310238 | The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I |
| Q35919836 | The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites |
| Q27674769 | The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling |
| Q37543198 | The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness |
| Q24320147 | The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA |
| Q41564761 | The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus |
| Q92571706 | The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders |
| Q40479603 | The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection. |
| Q63246498 | The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein |
| Q41936234 | The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy |
| Q37749473 | The chase for the RIG-I ligand--recent advances |
| Q39706057 | The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway |
| Q38045184 | The essential adaptors of innate immune signaling |
| Q34281428 | The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs |
| Q34145484 | The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly |
| Q37556622 | The laboratory of genetics and physiology 2: emerging insights into the controversial functions of this RIG-I-like receptor |
| Q39346072 | The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. |
| Q27653718 | The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA |
| Q40863011 | The role of immunostimulatory nucleic acids in septic shock |
| Q36001052 | The role of type I interferons in intestinal infection, homeostasis, and inflammation |
| Q37034554 | The role of viral nucleic acid recognition in dendritic cells for innate and adaptive antiviral immunity. |
| Q36968250 | The science of adjuvants |
| Q35028032 | Toll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses. |
| Q37174620 | Toll-like receptors and adaptor molecules in liver disease: update |
| Q27486231 | Toll-like receptors regulation of viral infection and disease☆ |
| Q36898663 | Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response |
| Q36774934 | Triggering the innate antiviral response through IRF-3 activation |
| Q40046657 | Tumour viruses and innate immunity |
| Q34608956 | Type B coxsackieviruses and their interactions with the innate and adaptive immune systems |
| Q26771789 | Ubiquitin in the activation and attenuation of innate antiviral immunity |
| Q37926284 | Ubiquitin-mediated modulation of the cytoplasmic viral RNA sensor RIG-I. |
| Q54217610 | Understanding Viral dsRNA-Mediated Innate Immune Responses at the Cellular Level Using a Rainbow Trout Model. |
| Q34388463 | Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I. |
| Q36282798 | Viperin interaction with mitochondrial antiviral signaling protein (MAVS) limits viperin-mediated inhibition of the interferon response in macrophages |
| Q38020836 | Viral CNS infections: role of glial pattern recognition receptors in neuroinflammation |
| Q28069090 | Viral Evasion Strategies in Type I IFN Signaling - A Summary of Recent Developments |
| Q38902137 | Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production |
| Q37361452 | Viral sensors: diversity in pathogen recognition |
| Q90198276 | Viroporins and inflammasomes: A key to understand virus-induced inflammation |
| Q57810083 | Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells |
| Q54996453 | Viruses Seen by Our Cells: The Role of Viral RNA Sensors. |
| Q38074266 | West Nile virus infection and immunity |
| Q22001518 | Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction |
| Q24307928 | ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses |
| Q41717615 | Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response. |
| Q54526400 | [RIG-I: a viral RNA detector molecular switch]. |
| Q35205757 | dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity |
| Q54232342 | miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11. |
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