| scholarly article | Q13442814 |
| P2093 | author name string | Hong Xia | |
| Judy Kahm | |||
| Richard Seonghun Nho | |||
| Craig A Henke | |||
| Jill Kleidon | |||
| P2860 | cites work | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation | Q24642901 |
| DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals | Q24672929 | ||
| Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. | Q24673519 | ||
| Disruption of epithelial cell-matrix interactions induces apoptosis | Q24673611 | ||
| PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway | Q28139300 | ||
| AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation | Q28139447 | ||
| Integrin signaling | Q28142010 | ||
| Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase | Q30442141 | ||
| Inhibition of pp125FAK in cultured fibroblasts results in apoptosis | Q30442183 | ||
| Control of adhesion-dependent cell survival by focal adhesion kinase | Q30442196 | ||
| Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis | Q30442817 | ||
| Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase | Q30453995 | ||
| Integrin signaling and matrix assembly | Q34383427 | ||
| Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex | Q34452252 | ||
| Flow-mediated endothelial mechanotransduction | Q34648558 | ||
| alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway | Q34721118 | ||
| Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions | Q35766403 | ||
| Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. | Q36255622 | ||
| The extracellular matrix as a cell survival factor | Q40241699 | ||
| Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. | Q41673423 | ||
| Cellular control lies in the balance of forces | Q41750971 | ||
| Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway | Q42618265 | ||
| Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase | Q42807993 | ||
| Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397. | Q42830397 | ||
| The focal adhesion targeting sequence is the major inhibitory moiety of Fak-related non-kinase | Q43812572 | ||
| Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades | Q43900381 | ||
| beta 1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway | Q43977769 | ||
| Integrin signalling and tyrosine phosphorylation: just the FAKs? | Q47721433 | ||
| Induction of lung fibroblast apoptosis by soluble fibronectin peptides. | Q52541242 | ||
| Normal Human Primary Fibroblasts Undergo Apoptosis in Three-Dimensional Contractile Collagen Gels | Q57758370 | ||
| MAP kinase activation by flow in endothelial cells. Role of beta 1 integrins and tyrosine kinases | Q71393665 | ||
| SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity | Q72993747 | ||
| Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis | Q77114860 | ||
| Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue | Q77380938 | ||
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | positive regulation of protein kinase B signaling | Q14761970 |
| Protein tyrosine kinase 2 | Q2744706 | ||
| P304 | page(s) | 33024-34 | |
| P577 | publication date | 2004-07-30 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway | |
| P478 | volume | 279 |
| Q42575346 | A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance |
| Q34362076 | ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling |
| Q34717955 | Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis |
| Q33724411 | Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling. |
| Q26852158 | Anoikis molecular pathways and its role in cancer progression |
| Q48363650 | Anti-invasive effects of CXCR4 and FAK inhibitors in non-small cell lung carcinomas with mutually inactivated p53 and PTEN tumor suppressors |
| Q48832123 | Apoptosis induced by SRC-family tyrosine kinase inhibitors in cultured rat cortical cells |
| Q39148631 | Attachment-regulated signaling networks in the fibroblast-populated 3D collagen matrix |
| Q36018543 | Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes |
| Q46949378 | CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts |
| Q33645244 | Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth |
| Q90283477 | Cell senescence altered the miRNA expression profile in porcine angular aqueous plexus cells |
| Q42085271 | Cell type-specific regulation of CCN2 protein expression by PI3K-AKT-FoxO signaling |
| Q54622127 | Changes in extracellular matrix composition regulate cyclooxygenase-2 expression in human mesangial cells. |
| Q37485980 | Changes in muscle mass with mechanical load: possible cellular mechanisms |
| Q40774629 | Characterization of crude Echis carinatus venom-induced cytotoxicity in HEK 293T cells |
| Q36796975 | Characterization of heparanase-induced phosphatidylinositol 3-kinase-AKT activation and its integrin dependence |
| Q50800683 | Chemically-defined scaffolds created with electrospun synthetic nanofibers to maintain mouse embryonic stem cell culture under feeder-free conditions. |
| Q35677074 | Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts |
| Q38996114 | Combined effects of dentin sialoprotein and bone morphogenetic protein-2 on differentiation in human cementoblasts. |
| Q42262267 | Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway |
| Q46979004 | Contraction of tubulointerstitial fibrosis tissue in diabetic nephropathy, as demonstrated in an in vitro fibrosis model |
| Q40305940 | Contribution of Src-FAK signaling to the induction of connective tissue growth factor in renal fibroblasts |
| Q37242874 | Cytotoxic effect of recombinant Mycobacterium tuberculosis CFP-10/ESAT-6 protein on the crucial pathways of WI-38 cells |
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| Q35088190 | Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents |
| Q36039352 | Endothelial FAK is required for tumour angiogenesis |
| Q42560002 | Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation |
| Q38556950 | Engineering nanoscale stem cell niche: direct stem cell behavior at cell-matrix interface. |
| Q42288266 | Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts |
| Q92669335 | Enhancement of FAK alleviates ventilator-induced alveolar epithelial cell injury |
| Q36427136 | Epithelial-mesenchymal interactions in pulmonary fibrosis |
| Q34360298 | Essential role for focal adhesion kinase in regulating stress hematopoiesis |
| Q91621157 | Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases |
| Q36493966 | Evolving concepts of apoptosis in idiopathic pulmonary fibrosis |
| Q93369514 | Exposure of the extracellular matrix and colonization of the ovary in metastasis of fallopian-tube-derived cancer |
| Q40245087 | Expression of cell kinetics and death during monocyte-macrophage differentiation: effects of Actinomycin D and Vinblastine treatments. |
| Q50464386 | Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models. |
| Q26753838 | Extracellular Matrix and Dermal Fibroblast Function in the Healing Wound |
| Q24311450 | FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction |
| Q43206192 | FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex |
| Q93080778 | FAK-Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer |
| Q37234240 | FERM control of FAK function: implications for cancer therapy. |
| Q34354577 | Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway |
| Q28397455 | Fibroblast engraftment in the decellularized mouse lung occurs via a β1-integrin-dependent, FAK-dependent pathway that is mediated by ERK and opposed by AKT |
| Q35801970 | Fibronectin induces endothelial cell migration through β1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766. |
| Q39081809 | Fibronectin promotes migration and invasion of ovarian cancer cells through up-regulation of FAK-PI3K/Akt pathway |
| Q33369846 | Fibrotic myofibroblasts manifest genome-wide derangements of translational control |
| Q40345475 | Focal adhesion kinase is activated in invading fibrosarcoma cells and regulates metastasis |
| Q39985969 | Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation |
| Q40374547 | Focal adhesion kinase signaling regulates cardiogenesis of embryonic stem cells |
| Q29615192 | Focal adhesion kinase: in command and control of cell motility |
| Q54943861 | FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death. |
| Q36778873 | GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells |
| Q38612342 | Heparan Sulfate Proteoglycan Deficiency Up-Regulates the Intracellular Production of Nitric Oxide in Chinese Hamster Ovary Cell Lines. |
| Q37353092 | Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway |
| Q28221076 | Hypertrophic scar formation following burns and trauma: new approaches to treatment |
| Q36140322 | Hypoxic niche-mediated regeneration of hematopoiesis in the engraftment window is dominantly affected by oxygen tension in the milieu. |
| Q24603371 | Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells |
| Q35146728 | IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases |
| Q24300127 | Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein |
| Q36440438 | Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy |
| Q41443789 | Idiopathic pulmonary fibrosis fibroblasts become resistant to Fas ligand-dependent apoptosis via the alteration of decoy receptor 3. |
| Q36047564 | In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking |
| Q37745105 | Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury |
| Q42155716 | Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts |
| Q37130568 | Inhibition of ERK promotes collagen gel compaction and fibrillogenesis to amplify the osteogenesis of human mesenchymal stem cells in three-dimensional collagen I culture |
| Q54124233 | Inhibition of cell migration by focal adhesion kinase: Time-dependent difference in integrin-induced signaling between endothelial and hepatoblastoma cells. |
| Q36489859 | Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway |
| Q38130473 | Integration of autophagy and anoikis resistance in solid tumors |
| Q47140528 | Integrin and FAK Regulation of Human Pluripotent Stem Cells. |
| Q58763822 | Integrin α5β1-Ang1/Tie2 receptor cross-talk regulates brain endothelial cell responses following cerebral ischemia |
| Q40979872 | Integrin α6β1 Expressed in ESCs Instructs the Differentiation to Endothelial Cells. |
| Q37665359 | Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer |
| Q37171520 | Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and Differentiation |
| Q39096530 | Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer |
| Q39113758 | Involvement of CD137 ligand signaling in neural stem cell death |
| Q41201511 | Kaempferol-3-O-rutinoside from Afgekia mahidoliae promotes keratinocyte migration through FAK and Rac1 activation. |
| Q40207125 | Keratins modulate hepatic cell adhesion, size and G1/S transition |
| Q89522206 | Laminin α5 modulates fibroblast proliferation in epidural fibrosis through the PI3K/AKT/mTOR signaling pathway |
| Q28469144 | Ligand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cells |
| Q36071822 | Low α(2)β(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the β-catenin pathway |
| Q36289344 | MCPIP1 Regulates Fibroblast Migration in 3-D Collagen Matrices Downstream of MAP Kinases and NF-κB |
| Q35987273 | Maintaining human fetal pancreatic stellate cell function and proliferation require β1 integrin and collagen I matrix interactions |
| Q34033929 | Mannheimia haemolytica leukotoxin induces apoptosis of bovine lymphoblastoid cells (BL-3) via a caspase-9-dependent mitochondrial pathway |
| Q54979519 | Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells. |
| Q26852563 | Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute |
| Q88973517 | Mechanisms and context underlying the role of autophagy in cancer metastasis |
| Q90424470 | Mechanisms for the Resolution of Organ Fibrosis |
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