| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Matthew W Conklin | Q57326297 |
| Pepper J Schedin | Q59160451 | ||
| Valerie M Weaver | Q67221999 | ||
| Victoria L Seewaldt | Q100406305 | ||
| Kevin Eliceiri | Q28367456 | ||
| P2093 | author name string | Patricia J Keely | |
| Christopher Sistrunk | |||
| J Matthew Barnes | |||
| Jason C Tung | |||
| Shraddha R Desai | |||
| P2860 | cites work | Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype | Q21562167 |
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway | Q24294542 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation | Q24322925 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth | Q24613142 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Matrix crosslinking forces tumor progression by enhancing integrin signaling | Q24646370 | ||
| AKT/PKB signaling: navigating downstream | Q24657857 | ||
| Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation | Q24680802 | ||
| Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 | Q24681460 | ||
| Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis | Q26830671 | ||
| Tensional homeostasis and the malignant phenotype | Q27860932 | ||
| On the Origin of Cancer Cells | Q27861025 | ||
| TIGAR, a p53-inducible regulator of glycolysis and apoptosis | Q28118306 | ||
| Correlation of magnetic resonance spectroscopic and growth characteristics within Grades II and III gliomas | Q48204510 | ||
| Strain processing of intraoperative ultrasound images of brain tumours: initial results | Q49143645 | ||
| Tools to study cell mechanics and mechanotransduction. | Q50961316 | ||
| Ultrasonic strain imaging and reconstructive elastography for biological tissue. | Q51158439 | ||
| Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland. | Q52005031 | ||
| Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. | Q53530417 | ||
| The nanomechanical signature of breast cancer | Q58463870 | ||
| Immunohistochemical study of type I collagen and type I pN-collagen in benign and malignant ovarian neoplasms | Q72503251 | ||
| Type I and III collagen metabolites as predictors of clinical outcome in epithelial ovarian cancer | Q73347576 | ||
| Expression of phosphatidylinositol-3 kinase in lung cancer | Q73688533 | ||
| Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc | Q73819236 | ||
| Aberrant type I and type III collagen gene expression in human breast cancer in vivo | Q77349737 | ||
| Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin: Response to Farooki and Schneider | Q80012747 | ||
| Phosphatidylinositol 3-kinase/AKT signalling pathway components in human breast cancer: clinicopathological correlations | Q80665514 | ||
| Prognostic potential of the pre-therapeutic tumor oxygenation status | Q83377028 | ||
| A tense situation: forcing tumour progression | Q37112264 | ||
| Collagen architecture in pregnancy-induced protection from breast cancer | Q37168882 | ||
| Breaking down barriers: the importance of the stromal microenvironment in acquiring invasiveness in young women's breast cancer | Q37208748 | ||
| Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer | Q37241740 | ||
| Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. | Q37245109 | ||
| LOXL2-mediated matrix remodeling in metastasis and mammary gland involution | Q37346579 | ||
| Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03. | Q37347497 | ||
| Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells | Q37351516 | ||
| 18F-FDG uptake in lung, breast, and colon cancers: molecular biology correlates and disease characterization | Q37440346 | ||
| Expression of metabolism-related proteins in triple-negative breast cancer | Q37452279 | ||
| Glucose promotes breast cancer aggression and reduces metformin efficacy. | Q37525828 | ||
| The role of focal adhesion kinase in tumor initiation and progression. | Q37582150 | ||
| Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors | Q37693081 | ||
| Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. | Q37694973 | ||
| Dynamic interplay between the collagen scaffold and tumor evolution | Q37786073 | ||
| Oxidative phosphorylation in cancer cells | Q37789810 | ||
| Tumor microenvironment is multifaceted | Q37832693 | ||
| PTEN loss in the continuum of common cancers, rare syndromes and mouse models. | Q37856722 | ||
| The tumor macroenvironment and systemic regulation of breast cancer progression | Q37967589 | ||
| Tumor microenvironment: a main actor in the metastasis process. | Q37982937 | ||
| Non-glucose metabolism in cancer cells--is it all in the fat? | Q38019411 | ||
| Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma | Q38990221 | ||
| 13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C-labeled glutamine | Q39955996 | ||
| Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells | Q40056669 | ||
| Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis. | Q40143359 | ||
| Ultraviolet-induced autofluorescence characterization of normal and tumoral esophageal epithelium cells with quantitation of NAD(P)H. | Q40281921 | ||
| Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH. | Q40365851 | ||
| Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly | Q40782515 | ||
| Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of the breast | Q41553767 | ||
| Metformin prevents the development of chronic heart failure in the SHHF rat model. | Q41885618 | ||
| Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis | Q41961097 | ||
| Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion. | Q42048391 | ||
| The relationship of expression of GLUT1,HIF-1α and the uptake of FDG in non-small cell lung cancer | Q42786427 | ||
| Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial | Q42920181 | ||
| Clinical outcomes after radical prostatectomy in diabetic patients treated with metformin | Q42971655 | ||
| Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway | Q43143850 | ||
| Correlation of ¹⁸F-FDG PET activity with expressions of survivin, Ki67, and CD34 in non-small-cell lung cancer | Q43280146 | ||
| Metabolic targets for cancer therapy | Q46213230 | ||
| The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation | Q46418283 | ||
| Biological correlation of ¹⁸F-FDG uptake on PET in pulmonary neuroendocrine tumors | Q46877702 | ||
| Cross Talk between Cellular Redox Status, Metabolism, and p53 in Neural Stem Cell Biology | Q46937723 | ||
| The cytoskeleton and cell signaling: component localization and mechanical coupling | Q47801990 | ||
| Tumor hypoxia and malignant progression. | Q47822417 | ||
| Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis | Q36562440 | ||
| In situ force mapping of mammary gland transformation | Q36588916 | ||
| Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus | Q36753875 | ||
| Tumor microenvironment promotes cancer progression, metastasis, and therapeutic resistance | Q36760601 | ||
| Vimentin filaments follow the preexisting cytokeratin network during epithelial-mesenchymal transition of cultured neonatal rat hepatocytes | Q36795484 | ||
| Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways | Q36802337 | ||
| Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation | Q36842018 | ||
| Vimentin and epithelial-mesenchymal transition in human breast cancer--observations in vitro and in vivo. | Q36857862 | ||
| Tensegrity-based mechanosensing from macro to micro | Q36942896 | ||
| Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer | Q36943123 | ||
| Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. | Q36989021 | ||
| Adiposity, the metabolic syndrome, and breast cancer in African-American and white American women | Q36992667 | ||
| Signalling through phosphoinositide 3-kinases: the lipids take centre stage | Q28141934 | ||
| Integrin signaling | Q28142010 | ||
| p53 regulates mitochondrial respiration | Q28242400 | ||
| Metformin induces unique biological and molecular responses in triple negative breast cancer cells | Q28244833 | ||
| Integrins in mechanotransduction | Q28244898 | ||
| Lysyl oxidase mediates hypoxic control of metastasis | Q28271667 | ||
| The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway | Q28298223 | ||
| Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis | Q28298687 | ||
| HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption | Q28300415 | ||
| Regulation of cancer cell metabolism | Q28303890 | ||
| Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate | Q28472161 | ||
| Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma | Q28540413 | ||
| Regulation of PTEN transcription by p53 | Q28646911 | ||
| Environmental sensing through focal adhesions | Q29615211 | ||
| Microenvironmental regulation of tumor progression and metastasis | Q29615504 | ||
| THE METABOLISM OF TUMORS IN THE BODY | Q29616202 | ||
| Metformin and reduced risk of cancer in diabetic patients | Q29616275 | ||
| Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors | Q29617042 | ||
| Production of large amounts of hydrogen peroxide by human tumor cells | Q29617080 | ||
| The LKB1-AMPK pathway: metabolism and growth control in tumour suppression | Q29617506 | ||
| The extracellular matrix: a dynamic niche in cancer progression | Q29617793 | ||
| Matrix metalloproteinases: regulators of the tumor microenvironment | Q29619858 | ||
| Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury | Q30414261 | ||
| Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. | Q30453215 | ||
| Collagen reorganization at the tumor-stromal interface facilitates local invasion | Q30478870 | ||
| Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas | Q30544282 | ||
| Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells | Q30802715 | ||
| Intra-operative 3D ultrasound in neurosurgery | Q33229815 | ||
| Multiphoton excitation of autofluorescence for microscopy of glioma tissue. | Q33238108 | ||
| Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation | Q33285396 | ||
| A hyperspectral fluorescence lifetime probe for skin cancer diagnosis | Q33312633 | ||
| Fluorescence lifetime imaging distinguishes basal cell carcinoma from surrounding uninvolved skin. | Q33331965 | ||
| Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer | Q33766299 | ||
| Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data | Q33795593 | ||
| Cancer and the tumor microenvironment: a review of an essential relationship | Q33806357 | ||
| Collagen density promotes mammary tumor initiation and progression | Q33845553 | ||
| Understanding the benefit of metformin use in cancer treatment | Q33864199 | ||
| Substrate flexibility regulates growth and apoptosis of normal but not transformed cells | Q33921181 | ||
| Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth | Q33925322 | ||
| Molecular basis of mechanotransduction in living cells. | Q33939989 | ||
| GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer | Q34003440 | ||
| Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment | Q34099325 | ||
| Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation | Q34103419 | ||
| Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival | Q34269713 | ||
| Persistent oxidative stress in cancer | Q34315954 | ||
| A tabulated summary of the FDG PET literature. | Q34325136 | ||
| Metformin in cancer prevention and therapy | Q34357983 | ||
| Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate | Q34359533 | ||
| Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression | Q34413051 | ||
| PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. | Q34438439 | ||
| Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. | Q34551523 | ||
| Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence | Q34572312 | ||
| Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis | Q34700500 | ||
| Body size, physical activity, and risk of triple-negative and estrogen receptor-positive breast cancer | Q34722266 | ||
| Aligned collagen is a prognostic signature for survival in human breast carcinoma | Q34760807 | ||
| Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage | Q35007822 | ||
| PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer. | Q35038068 | ||
| Subtle variations in Pten dose determine cancer susceptibility | Q35055350 | ||
| Metabolic Syndrome and Breast Cancer Risk: Is There a Role for Metformin? | Q35161241 | ||
| Adhesion-dependent cell mechanosensitivity. | Q35564866 | ||
| Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS. | Q35906419 | ||
| The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production | Q36118624 | ||
| In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia | Q36288673 | ||
| Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition | Q36312242 | ||
| Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells | Q36321798 | ||
| ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix | Q36324827 | ||
| The Regulation of Multiple p53 Stress Responses is Mediated through MDM2 | Q36387610 | ||
| Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival | Q36549632 | ||
| P304 | page(s) | 269-280 | |
| P577 | publication date | 2014-12-19 | |
| P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
| P1476 | title | Tumor mechanics and metabolic dysfunction | |
| P478 | volume | 79 |
| Q40518800 | A prognostic profile of hypoxia-induced genes for localised high-grade soft tissue sarcoma |
| Q94070972 | Advancements in Free-Radical Pathologies and an Important Treatment Solution with a Free-Radical Inhibitor |
| Q91754592 | Ag Nanoparticles/α-Ag2WO4 Composite Formed by Electron Beam and Femtosecond Irradiation as Potent Antifungal and Antitumor Agents |
| Q51152292 | Breaching the Hyaluronan Barrier with PH20-Fc Facilitates Intratumoral Permeation and Enhances Antitumor Efficiency: A Comparative Investigation of Typical Therapeutic Agents in Different Nanoscales. |
| Q50969508 | Cell forces meet cell metabolism. |
| Q38383936 | Development by three-dimensional approaches and four-dimensional imaging: to the knowledge frontier and beyond |
| Q37708946 | Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma |
| Q36063668 | Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening |
| Q37226057 | Down-Regulated Phosphoglycerate Kinase 1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Cancer |
| Q37284384 | Engineered bacteria detect spatial profiles in glucose concentration within solid tumor cell masses |
| Q51551094 | Engineered tumours: Roll-on scaffolds. |
| Q38712123 | Extracellular Proton Concentrations Impacts LN229 Glioblastoma Tumor Cell Fate via Differential Modulation of Surface Lipids |
| Q46277412 | FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis |
| Q47376188 | Fibrosis imaging: Current concepts and future directions |
| Q57817200 | Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels |
| Q37689086 | Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection |
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| Q37694744 | ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer |
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| Q89980729 | Metabolism of pancreatic cancer: paving the way to better anticancer strategies |
| Q61444957 | Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer |
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| Q53078069 | Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity. |
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