PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1.

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PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...745806G
P356DOI10.1371/JOURNAL.PONE.0045806
P932PMC publication ID3458951
P698PubMed publication ID23049865
P5875ResearchGate publication ID232226954

P2093author name stringHeng-Phon Too
Marie-Veronique Clement
Kim Ping Wong
Hwee Ying Lim
Qin Shi Ho
Chong Kiat Goo
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Portrait of PTEN: messages from mutant mice.Q37059129
Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.Q37325401
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mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPsQ39699300
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Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosisQ42601114
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Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeastQ21146425
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complexQ24295120
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
AKT/PKB signaling: navigating downstreamQ24657857
Measurement of protein using bicinchoninic acidQ26778491
Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localizationQ27301294
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The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeastQ27929773
Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteinsQ27938336
4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implicationsQ28240822
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenaseQ28565525
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1Q29614563
Molecular mechanisms of mTOR-mediated translational controlQ29615529
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicityQ29616651
Akt stimulates aerobic glycolysis in cancer cellsQ29619301
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayQ29620730
A PUF family portrait: 3'UTR regulation as a way of lifeQ30080015
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activationQ31034955
Direct control of mitochondrial function by mTOR.Q33552261
Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomographyQ34028316
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory networkQ34142560
In vivo and in organello assessment of OXPHOS activitiesQ34675859
PTEN hamartoma tumor syndrome: an overviewQ34996547
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)e45806
P577publication date2012-09-26
P1433published inPLOS OneQ564954
P1476titlePTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1.
P478volume7

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