| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S00018-016-2258-2 |
| P8608 | Fatcat ID | release_l2fezlyvlzam5lvs5x7kv657dq |
| P698 | PubMed publication ID | 27147463 |
| P50 | author | Paulo Matos | Q39965031 |
| Peter Jordan | Q39965078 | ||
| Margarida Duarte Amaral | Q40348869 | ||
| Cláudia Loureiro | Q57070016 | ||
| P2093 | author name string | Nikhil T Awatade | |
| Joana F S Pereira | |||
| P2860 | cites work | Epithelial cell coculture models for studying infectious diseases: benefits and limitations | Q21296749 |
| COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer | Q24608391 | ||
| Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures | Q24679747 | ||
| Advances in the formation, use and understanding of multi-cellular spheroids | Q26828808 | ||
| Peptide Hydrogels - Versatile Matrices for 3D Cell Culture in Cancer Medicine | Q26860533 | ||
| Molecular aspects of tight junction barrier function | Q26864785 | ||
| Forms, forces, and stem cell fate | Q26995659 | ||
| Mechanotransduction and extracellular matrix homeostasis | Q26998075 | ||
| CFTR functional measurements in human models for diagnosis, prognosis and personalized therapy: Report on the pre-conference meeting to the 11th ECFS Basic Science Conference, Malta, 26-29 March 2014 | Q27001087 | ||
| Microfabricated mammalian organ systems and their integration into models of whole animals and humans | Q27011459 | ||
| Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors | Q27023623 | ||
| Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip | Q27316911 | ||
| FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing. | Q27325401 | ||
| TEER measurement techniques for in vitro barrier model systems | Q28086851 | ||
| Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 | ||
| CD44: from adhesion molecules to signalling regulators | Q28201701 | ||
| Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Q28239639 | ||
| Engineered in vitro disease models. | Q38332700 | ||
| A guide to mechanobiology: Where biology and physics meet | Q38495688 | ||
| Mechanoreception at the cell membrane: More than the integrins | Q38560564 | ||
| Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression. | Q38636963 | ||
| SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer | Q38792830 | ||
| Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells. | Q38837736 | ||
| Efficient genetic engineering of human intestinal organoids using electroporation | Q38838399 | ||
| Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer | Q38840520 | ||
| Media additives to promote spheroid circularity and compactness in hanging drop platform | Q38848678 | ||
| Acetylcarnitine potentiates the anticarcinogenic effects of butyrate on SW480 colon cancer cells | Q38867543 | ||
| Prospective derivation of a living organoid biobank of colorectal cancer patients. | Q38877277 | ||
| Dissecting stromal-epithelial interactions in a 3D in vitro cellularized intestinal model for permeability studies | Q38880030 | ||
| Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium. | Q38984674 | ||
| Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays | Q38998478 | ||
| Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer | Q39001975 | ||
| Cellular localization, invasion, and turnover are differently influenced by healthy and tumor-derived extracellular matrix | Q39026929 | ||
| Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study | Q39039945 | ||
| Toxicity of commercially available engineered nanoparticles to Caco-2 and SW480 human intestinal epithelial cells | Q39184058 | ||
| 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing | Q39187713 | ||
| TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells | Q39393535 | ||
| Isolation and characterization of spheroid cells from the HT29 colon cancer cell line | Q39525075 | ||
| Functional characterization of MIMP for its adhesion to the intestinal epithelium | Q39534229 | ||
| Caco-2 and LS174T cell lines provide different models for studying mucin expression in colon cancer | Q39563275 | ||
| A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration | Q39642490 | ||
| T84 cells in culture as a model for enteroaggregative Escherichia coli pathogenesis | Q39826624 | ||
| Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells. | Q39914340 | ||
| A reliable tool to determine cell viability in complex 3-d culture: the acid phosphatase assay | Q40066461 | ||
| S-adenosyl L-methionine inhibits azoxymethane-induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco-2 cell growth in 3D culture | Q40088592 | ||
| Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis | Q40147027 | ||
| Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications | Q38112669 | ||
| Concise review: the yin and yang of intestinal (cancer) stem cells and their progenitors | Q38120218 | ||
| Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration | Q38170259 | ||
| 3D cell culture systems modeling tumor growth determinants in cancer target discovery | Q38196612 | ||
| Organoid cultures for the analysis of cancer phenotypes | Q38198433 | ||
| Three-dimensional in vitro cancer models: a short review | Q38204215 | ||
| Matrigel: from discovery and ECM mimicry to assays and models for cancer research. | Q38226546 | ||
| Synthesis and high-throughput processing of polymeric hydrogels for 3D cell culture. | Q38242844 | ||
| Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo | Q38244951 | ||
| The extracellular matrix modulates the hallmarks of cancer | Q38266276 | ||
| Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro | Q38269801 | ||
| Persistent use of "false" cell lines | Q28254701 | ||
| A functional CFTR assay using primary cystic fibrosis intestinal organoids | Q28291898 | ||
| Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients | Q28303521 | ||
| Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells | Q28485464 | ||
| Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression | Q29614274 | ||
| Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies | Q29614313 | ||
| Taking cell-matrix adhesions to the third dimension | Q29615214 | ||
| Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion | Q29617359 | ||
| Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport | Q30321148 | ||
| Cancer stem cells from colorectal cancer-derived cell lines. | Q30493732 | ||
| In vitro generation of colonic epithelium from primary cells guided by microstructures | Q30579116 | ||
| Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology | Q30717134 | ||
| Morphological and cytoskeletal changes caused by non-membrane damaging cytotoxin of Vibrio cholerae on int 407 and HeLa cells | Q30789888 | ||
| Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2 | Q33200951 | ||
| How cells sense extracellular matrix stiffness: a material's perspective | Q33680791 | ||
| Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model. | Q33771791 | ||
| Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery | Q33794878 | ||
| Dynamic transcription factor activity profiling in 2D and 3D cell cultures | Q33815599 | ||
| Much ado about M cells | Q33877091 | ||
| Epithelial cell polarity as reflected in enterocytes | Q33924101 | ||
| Matrigel: a complex protein mixture required for optimal growth of cell culture. | Q34021289 | ||
| Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. | Q34032640 | ||
| Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1 | Q34068310 | ||
| Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin. | Q34083378 | ||
| Regulation of intestinal epithelial permeability by tight junctions. | Q34287155 | ||
| Clinical development success rates for investigational drugs | Q34396786 | ||
| The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics. | Q34415669 | ||
| Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes | Q34418858 | ||
| Measurements of CFTR-mediated Cl- secretion in human rectal biopsies constitute a robust biomarker for Cystic Fibrosis diagnosis and prognosis. | Q34452224 | ||
| Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability | Q34561438 | ||
| Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines | Q34651865 | ||
| The phosphatidylinositol 3-kinase inhibitor, PX-866, is a potent inhibitor of cancer cell motility and growth in three-dimensional cultures | Q34674397 | ||
| Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors | Q34703085 | ||
| Three-dimensional cell culture matrices: state of the art. | Q34775700 | ||
| Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulation | Q34838011 | ||
| Knockout of MIMP protein in lactobacillus plantarum lost its regulation of intestinal permeability on NCM460 epithelial cells through the zonulin pathway | Q34875626 | ||
| Hydrogels as extracellular matrix mimics for 3D cell culture. | Q34983262 | ||
| Advancing science and technology via 3D culture on basement membrane matrix | Q34984619 | ||
| Adaptation of core mechanisms to generate cell polarity | Q35109711 | ||
| Tumor mechanics and metabolic dysfunction | Q35117423 | ||
| Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery. | Q35575499 | ||
| Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer | Q35605606 | ||
| The intestinal epithelium as guardian of gut barrier integrity | Q35751873 | ||
| Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo | Q35754364 | ||
| A three-dimensional system for long-term culture of human colorectal adenomas | Q35812168 | ||
| Robotic production of cancer cell spheroids with an aqueous two-phase system for drug testing | Q35970782 | ||
| Coordinated protein sorting, targeting and distribution in polarized cells | Q36015653 | ||
| LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis | Q36040577 | ||
| Self-renewal and cancer of the gut: two sides of a coin. | Q36080124 | ||
| Keynote review: intestinal Peyer's patch M cells and oral vaccine targeting. | Q36266985 | ||
| Cellular chloride and bicarbonate retention alters intracellular pH regulation in Cftr KO crypt epithelium | Q36480411 | ||
| In vitro neutrophil transepithelial migration | Q36518754 | ||
| Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b | Q36567588 | ||
| Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology | Q36594641 | ||
| CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness | Q36769451 | ||
| HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: in vitro-in vivo correlation with permeability data from rats and humans | Q36830229 | ||
| The tumor microenvironment is a dominant force in multidrug resistance. | Q36856829 | ||
| Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. | Q36869902 | ||
| Genetic reconstitution of tumorigenesis in primary intestinal cells | Q36990814 | ||
| A novel tissue engineered three-dimensional in vitro colorectal cancer model | Q37012173 | ||
| M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis. | Q37032884 | ||
| Epigenetic and genetic features of 24 colon cancer cell lines | Q37275764 | ||
| Engineering tumors: a tissue engineering perspective in cancer biology | Q37679204 | ||
| Multicellular tumor spheroids: an underestimated tool is catching up again. | Q37680413 | ||
| LGR5 positivity defines stem-like cells in colorectal cancer | Q37687330 | ||
| Deconstructing signaling in three dimensions | Q37701392 | ||
| Molecular regulation of lumen morphogenesis. | Q37837188 | ||
| Composition and functional role of the mucus layers in the intestine | Q37938766 | ||
| From 3D cell culture to organs-on-chips | Q37950229 | ||
| The cytoskeleton in development of epithelial cell polarity | Q40387499 | ||
| HT29-MTX and Caco-2/TC7 monolayers as predictive models for human intestinal absorption: role of the mucus layer | Q40672135 | ||
| Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes | Q40778287 | ||
| Positive and negative regulation of chloride secretion in T84 cells | Q40779327 | ||
| The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications | Q40947744 | ||
| Alginate hydrogels as synthetic extracellular matrix materials | Q40978578 | ||
| Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon. | Q41005959 | ||
| Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria | Q41094317 | ||
| A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model | Q41138277 | ||
| Role of laminin-1 and TGF-beta 3 in acinar differentiation of a human submandibular gland cell line (HSG). | Q41178672 | ||
| Uncoordinated, transient mosaic patterns of intestinal hydrolase expression in differentiating human enterocytes | Q41255452 | ||
| Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations | Q41515597 | ||
| Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell line. | Q41609857 | ||
| Morphologic differentiation of colon carcinoma cell lines HT-29 and HT-29KM in rotating-wall vessels | Q41644797 | ||
| The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues | Q41737293 | ||
| Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro | Q41770080 | ||
| Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells | Q41877034 | ||
| The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer | Q42044314 | ||
| Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction | Q42045002 | ||
| Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation | Q42440768 | ||
| NCM460, a normal human colon mucosal epithelial cell line | Q42812955 | ||
| The importance of release of proinflammatory cytokines, ROS, and NO in different stages of colon carcinoma growth and metastasis after treatment with cytotoxic drugs. | Q43044414 | ||
| Defining conditions for the co-culture of Caco-2 and HT29-MTX cells using Taguchi design | Q43160625 | ||
| Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs | Q44735346 | ||
| Microfabrication of human organs-on-chips. | Q45924666 | ||
| Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. | Q51541144 | ||
| Sequential cancer mutations in cultured human intestinal stem cells. | Q52423597 | ||
| The establishment of strains of human cells in tissue culture. | Q52831945 | ||
| 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions. | Q52879768 | ||
| Advances in the preclinical testing of cancer therapeutic hypotheses. | Q53264472 | ||
| A tunable Caco-2/HT29-MTX co-culture model mimicking variable permeabilities of the human intestine obtained by an original seeding procedure. | Q53581491 | ||
| A microfluidic device with 3-d hydrogel villi scaffold to simulate intestinal absorption. | Q53669687 | ||
| Isolation and in vitro expansion of human colonic stem cells. | Q54350641 | ||
| High drug attrition rates--where are we going wrong? | Q55054118 | ||
| CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis | Q57762440 | ||
| Campylobacter jejuni cell lysates differently target mitochondria and lysosomes on HeLa cells | Q60692687 | ||
| Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium | Q63406947 | ||
| The role of the arginine-glycine-aspartic acid-directed cellular binding to type I collagen and rat mesenchymal cells in colorectal tumour differentiation | Q70221468 | ||
| Comparison of the adherence of three Lactobacillus strains to Caco-2 and Int-407 human intestinal cell lines | Q71227144 | ||
| The human intestinal cell lines Caco-2 and LS174T as models to study cell-type specific mucin expression | Q71762344 | ||
| A human colonic tumor cell line that maintains vectorial electrolyte transport | Q72572397 | ||
| Expression of specific markers and particle transport in a new human intestinal M-cell model | Q73404961 | ||
| Defective cholinergic Cl(-) secretion and detection of K(+) secretion in rectal biopsies from cystic fibrosis patients | Q73670570 | ||
| An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells | Q79754770 | ||
| Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase | Q80230070 | ||
| Microparticle transport in the human intestinal M cell model | Q80439858 | ||
| P433 | issue | 21 | |
| P304 | page(s) | 3971-3989 | |
| P577 | publication date | 2016-05-04 | |
| P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
| P1476 | title | The third dimension: new developments in cell culture models for colorectal research | |
| P478 | volume | 73 |
| Q90677093 | Characterization and In Vivo Validation of a Three-Dimensional Multi-Cellular Culture Model to Study Heterotypic Interactions in Colorectal Cancer Cell Growth, Invasion and Metastasis |
| Q41916600 | Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (Eugenol) on Inflammatory and Apoptosis Processes in Dental Pulp Fibroblasts. |
| Q55035407 | Microfluidic Organ-on-a-Chip Models of Human Intestine. |
| Q52639286 | Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions. |
| Q90182028 | Routine Optical Clearing of 3D-Cell Cultures: Simplicity Forward |
| Q64999288 | Spontaneous and cytokine-induced hole formation in epithelial cell layers: Implications for barrier function studies with the gingival cell culture, Gie-3B11, and other epithelial models. |
| Q51508755 | Use of a Collagen Membrane to Enhance the Survival of Primary Intestinal Epithelial Cells. |
Search more.