| review article | Q7318358 |
| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2005Sci...307.1904R |
| P356 | DOI | 10.1126/SCIENCE.1104815 |
| P8608 | Fatcat ID | release_k25jfu27ezglfaez6nftozszsi |
| P698 | PubMed publication ID | 15790842 |
| P5875 | ResearchGate publication ID | 7944771 |
| P50 | author | Freddy Radtke | Q41621239 |
| P2093 | author name string | Hans Clevers | |
| P433 | issue | 5717 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 6 | |
| P304 | page(s) | 1904-1909 | |
| P577 | publication date | 2005-03-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Self-renewal and cancer of the gut: two sides of a coin | |
| P478 | volume | 307 |
| Q33279153 | (A)symmetric stem cell replication and cancer |
| Q27334159 | A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt |
| Q38655276 | A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium. |
| Q27860831 | A human colon cancer cell capable of initiating tumour growth in immunodeficient mice |
| Q37709067 | A new paradigm of bacteria-gut interplay brought through the study of Shigella |
| Q58164878 | A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth |
| Q38008209 | A review of spatial computational models for multi-cellular systems, with regard to intestinal crypts and colorectal cancer development |
| Q25256726 | A transcriptome anatomy of human colorectal cancers |
| Q35558499 | A two-gene blood test for methylated DNA sensitive for colorectal cancer |
| Q37421928 | A van der Waals-like Transition Between Normal and Cancerous Phases in Cell Populations Dynamics of Colorectal Cancer |
| Q33762815 | ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics |
| Q37635945 | APC and its modifiers in colon cancer. |
| Q28567061 | Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression |
| Q37317346 | Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism |
| Q40222493 | Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases |
| Q26826943 | Adult Hepatic Progenitor Cell Niche: How it affects the Progenitor Cell Fate |
| Q41669839 | Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells |
| Q41903928 | Alterations in epithelial and mesenchymal intestinal gene expression during doxorubicin-induced mucositis in mice |
| Q35958425 | Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice |
| Q53013784 | Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells. |
| Q37795965 | An Overview of Concepts for Cancer Stem Cells |
| Q42080504 | An agent-based model of anoikis in the colon crypt displays novel emergent behaviour consistent with biological observations |
| Q28474993 | Atonal homolog 1 is a tumor suppressor gene |
| Q39016335 | Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. |
| Q42157352 | BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation |
| Q45986472 | Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. |
| Q38995402 | Biochemical analysis of force-sensitive responses using a large-scale cell stretch device. |
| Q37122732 | Bloodlines of haematopoietic stem cell research in Japan |
| Q36740051 | Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells |
| Q41858389 | Buckling of a growing tissue and the emergence of two-dimensional patterns |
| Q93106187 | CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis |
| Q35167602 | CD44 functions in Wnt signaling by regulating LRP6 localization and activation |
| Q35048348 | CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells |
| Q33705126 | CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis. |
| Q35591995 | Can we safely target the WNT pathway? |
| Q33867131 | Cancer stem cells: a novel paradigm for cancer prevention and treatment |
| Q84109267 | Cancer stem cells: nature versus nurture |
| Q34462269 | Carnitine deficiency in OCTN2-/- newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response |
| Q34998590 | Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts. |
| Q36403593 | Chemoprevention of benzo(a)pyrene-induced colon polyps in ApcMin mice by resveratrol |
| Q40130445 | Chemotherapy-induced mucositis is associated with changes in proteolytic pathways |
| Q38970526 | Colocalization of β-catenin with Notch intracellular domain in colon cancer: a possible role of Notch1 signaling in activation of CyclinD1-mediated cell proliferation |
| Q61788251 | Colon cancer stem cells |
| Q27339524 | Colon stem cell and crypt dynamics exposed by cell lineage reconstruction |
| Q37220194 | Colonic and colorectal cancer stem cells: progress in the search for putative biomarkers |
| Q33720978 | Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs |
| Q37091832 | Colorectal carcinogenesis: a cellular response to sustained risk environment. |
| Q33300134 | Comparing the DNA hypermethylome with gene mutations in human colorectal cancer |
| Q30855650 | Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery |
| Q46961784 | Complex patterns of ETS gene alteration arise during cancer development in the human prostate |
| Q34147618 | Computational model of cell positioning: directed and collective migration in the intestinal crypt epithelium. |
| Q43167823 | Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow |
| Q36973786 | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells |
| Q40097115 | Convergence of Notch and beta-catenin signaling induces arterial fate in vascular progenitors |
| Q36236802 | Crosstalk between Nrf2 and Notch signaling. |
| Q52002352 | Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. |
| Q34258054 | DNA polymerase beta-catalyzed-PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post-mitotic brain |
| Q31813071 | DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis |
| Q37581649 | Debra-mediated Ci degradation controls tissue homeostasis in Drosophila adult midgut |
| Q35048299 | Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis |
| Q34212591 | Deregulated inflammasome signaling in disease |
| Q101216865 | Desacetyl-α-MSH and α-MSH have sex specific interactions with diet to influence mouse gut morphology, metabolites and microbiota |
| Q34313844 | Dietary fat-influenced development of colon neoplasia in Apc Min mice exposed to benzo(a)pyrene |
| Q27329003 | Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture |
| Q42407375 | Diversity in the molecular and cellular strategies of epithelium-to-mesenchyme transitions: Insights from the neural crest. |
| Q38814296 | Downregulation of SMC1A inhibits growth and increases apoptosis and chemosensitivity of colorectal cancer cells |
| Q33777566 | Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection |
| Q35037269 | Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development |
| Q46761462 | Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence |
| Q37966605 | Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers |
| Q52695262 | E-cadherin prolongs the moment for interaction between intestinal stem cell and its progenitor cell to ensure Notch signaling in adult Drosophila midgut. |
| Q37658959 | E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling |
| Q34592495 | EGF signaling regulates the proliferation of intestinal stem cells in Drosophila |
| Q37561771 | EGFR(S) inhibitors in the treatment of gastro-intestinal cancers: what's new? |
| Q37552436 | EGFR(s) in aging and carcinogenesis of the gastrointestinal tract. |
| Q52609447 | EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells. |
| Q27310105 | EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes |
| Q41871121 | EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila |
| Q47962064 | Early genetic aberrations in patients with sporadic colorectal cancer |
| Q43246930 | Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment: results from a prospective, ran |
| Q61798112 | Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types |
| Q37542578 | Endocytosis, asymmetric cell division, stem cells and cancer: unus pro omnibus, omnes pro uno |
| Q37336696 | Endogenous lung stem cells and contribution to disease |
| Q37623437 | Endoplasmic reticulum stress and intestinal inflammation |
| Q90438838 | Engineering cell heterogeneity into organs-on-a-chip |
| Q37333742 | Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks |
| Q54982528 | Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization. |
| Q40393464 | Enzymes involved in L-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: implications for gut health |
| Q34285451 | Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndrome |
| Q38841415 | Epithelial cell extrusion: Pathways and pathologies. |
| Q36690919 | Epithelial stem cells: turning over new leaves |
| Q52663260 | Evidence that stem cells reside in the adult Drosophila midgut epithelium. |
| Q27680503 | Evolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2 |
| Q44434381 | Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer. |
| Q50978303 | Expression and clinical significance of Notch signaling genes in colorectal cancer. |
| Q42468040 | Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with beta-catenin |
| Q37217451 | Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth |
| Q24311824 | Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells |
| Q38989294 | Extracellular Matrix and Colorectal Cancer: How Surrounding Microenvironment Affects Cancer Cell Behavior? |
| Q37097913 | Feedback Regulation in a Cancer Stem Cell Model can Cause an Allee Effect. |
| Q34618753 | Fibroblast growth factor receptor 2c signaling is required for intestinal cell differentiation in zebrafish |
| Q90640303 | Frequent Activation of Notch Signaling Pathway in Colorectal Cancers and Its Implication in Patient Survival Outcome |
| Q27004534 | From fly wings to targeted cancer therapies: a centennial for notch signaling |
| Q50501047 | Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell. |
| Q37138197 | Functional role of Notch signaling in the developing and postnatal heart |
| Q34420897 | Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine |
| Q33294105 | GSK-3 inhibitors induce chromosome instability |
| Q39120190 | Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells |
| Q39925551 | Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells |
| Q37897490 | Gastrointestinal stem cells in self-renewal and cancer |
| Q37040950 | Genetic variations in stem cell-related genes and colorectal cancer prognosis |
| Q36540321 | Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells |
| Q38223273 | Glutamine and intestinal barrier function |
| Q40124526 | Glutamine regulates the human epithelial intestinal HCT-8 cell proteome under apoptotic conditions |
| Q28074181 | Guanylyl cyclase C signaling axis and colon cancer prevention |
| Q24303785 | Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin |
| Q37099380 | Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma |
| Q36635519 | Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon |
| Q40046463 | Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system |
| Q35864246 | Hes1 Increases the Invasion Ability of Colorectal Cancer Cells via the STAT3-MMP14 Pathway. |
| Q34698817 | High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients |
| Q35049311 | High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. |
| Q47435526 | Hippo, TGF-β, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection |
| Q57422101 | Histological overlap between colorectal villous/tubulovillous and traditional serrated adenomas |
| Q92651594 | Homeostasis and systematic ageing as non-equilibrium phase transitions in computational multicellular organizations |
| Q36202841 | Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. |
| Q42220559 | Hoxb13 regulatory elements mediate transgene expression during prostate organogenesis and carcinogenesis |
| Q21260380 | Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states |
| Q51541144 | Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. |
| Q46140184 | Human tissue-engineered colon forms from postnatal progenitor cells: an in vivo murine model |
| Q34513657 | Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling |
| Q36288682 | ID genes mediate tumor reinitiation during breast cancer lung metastasis |
| Q35013368 | IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation |
| Q39277983 | IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a. |
| Q28510385 | IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade |
| Q58482772 | Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression |
| Q33787896 | Impact of tiny miRNAs on cancers |
| Q33331795 | In vivo gene expression profiling of human intestinal epithelial cells: analysis by laser microdissection of formalin fixed tissues |
| Q36296267 | Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila |
| Q36072651 | Inflammasomes and Intestinal Tumorigenesis |
| Q39237282 | Inflammasomes and intestinal inflammation |
| Q33482165 | Influence of smoking on colonic gene expression profile in Crohn's disease |
| Q33479798 | Integrin alpha6Bbeta4 inhibits colon cancer cell proliferation and c-Myc activity |
| Q43192584 | Interleukin-1 receptor signaling protects mice from lethal intestinal damage caused by the attaching and effacing pathogen Citrobacter rodentium. |
| Q47154871 | Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity |
| Q34796870 | Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation |
| Q38164704 | Intestinal acyl-CoA synthetase 5: activation of long chain fatty acids and behind |
| Q28474823 | Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis |
| Q90685529 | Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds |
| Q37164036 | Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal |
| Q37379590 | Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila |
| Q35175249 | Investigating the relation between stochastic differentiation, homeostasis and clonal expansion in intestinal crypts via multiscale modeling |
| Q41966153 | Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis |
| Q39405395 | JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. |
| Q41895017 | JNK signalling modulates intestinal homeostasis and tumourigenesis in mice |
| Q33764707 | Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1. |
| Q36854925 | JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function |
| Q35269425 | Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine |
| Q42241490 | Krüppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection |
| Q36917052 | LKB1 induces apical trafficking of Silnoon, a monocarboxylate transporter, in Drosophila melanogaster |
| Q57191753 | Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients |
| Q34594582 | Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection |
| Q36983184 | Laminin alpha 5 influences the architecture of the mouse small intestine mucosa |
| Q27345444 | Lifespan extension by preserving proliferative homeostasis in Drosophila |
| Q43271997 | Long-term exposure to various types of dietary fat modulates acrylamide-induced preneoplastic lesions of colon mucosa through Wnt/beta-catenin signaling in rats |
| Q28579732 | Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats |
| Q36528951 | Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. |
| Q26852586 | Maintaining tissue homeostasis: dynamic control of somatic stem cell activity |
| Q24612560 | Mammalian Krüppel-Like Factors in Health and Diseases |
| Q37427798 | Management of the human mucosal defensive barrier: evidence for glycan legislation |
| Q42211947 | Mapping the Deltex-binding surface on the notch ankyrin domain using analytical ultracentrifugation |
| Q36580274 | Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity |
| Q36559283 | Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy |
| Q36467836 | Mechanisms of disease: from stem cells to colorectal cancer. |
| Q54795628 | Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin. |
| Q27302913 | Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt |
| Q33233373 | Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches |
| Q28513112 | Monitoring Notch1 activity in development: evidence for a feedback regulatory loop |
| Q35941365 | Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved |
| Q33611548 | Morphological and molecular evidence for functional organization along the rostrocaudal axis of the adult zebrafish intestine |
| Q33684472 | Mouse models for cancer stem cell research |
| Q36435973 | Multiple functions of Notch signaling in self-renewing organs and cancer. |
| Q30408477 | N-ethylmaleimide-sensitive factor attachment protein α (αSNAP) regulates matrix adhesion and integrin processing in human epithelial cells |
| Q33547282 | NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon |
| Q35150890 | NLRPs, microbiota, and gut homeostasis: unravelling the connection. |
| Q33883897 | NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts |
| Q33596234 | New intracellular and molecular aspects in pathophysiology of colorectal cancer |
| Q37302750 | New wirings in the survivin networks |
| Q37071851 | Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion |
| Q35821670 | Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche |
| Q35208718 | Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells |
| Q38635489 | Notch post-translationally regulates β-catenin protein in stem and progenitor cells |
| Q36317949 | Notch signaling in hematopoietic stem cells |
| Q37785204 | Notch signaling in solid tumors. |
| Q34982347 | Notch signaling proteins: legitimate targets for cancer therapy |
| Q40396715 | Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells. |
| Q52670911 | Notch synergizes with axin to regulate the activity of armadillo in Drosophila. |
| Q41813687 | Novel double-negative feedback loop between adenomatous polyposis coli and Musashi1 in colon epithelia |
| Q38114502 | Novel drug discovery opportunities for colorectal cancer |
| Q39522017 | Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer |
| Q89771836 | Overview of Basic Mechanisms of Notch Signaling in Development and Disease |
| Q27316304 | PTEN-deficient intestinal stem cells initiate intestinal polyposis |
| Q44694317 | Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells |
| Q37730965 | Pathogenic stimulation of intestinal stem cell response in Drosophila |
| Q24674126 | Phenotypic characterization of human colorectal cancer stem cells |
| Q35637318 | Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective |
| Q34494992 | Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis |
| Q38186823 | Postembryonic organogenesis of the digestive tube: why does it occur in worms and sea cucumbers but fail in humans? |
| Q28571361 | Pro-inflammatory cytokine interleukin-1β promotes the development of intestinal stem cells |
| Q36402193 | Probiotics and prebiotics in human health. |
| Q33414418 | Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour |
| Q42019069 | Prostaglandin-secreting cells: a portable first aid kit for tissue repair |
| Q37124964 | Prostate stem cells: the niche and cell markers |
| Q37174121 | Protective and destructive innate immune responses to enteropathogenic Escherichia coli and related A/E pathogens |
| Q28487798 | Protein kinase C delta negatively modulates canonical Wnt pathway and cell proliferation in colon tumor cell lines |
| Q37929700 | Protein kinase C in Wnt signaling: implications in cancer initiation and progression |
| Q54352733 | Protein kinase C ζ is a positive modulator of canonical Wnt signaling pathway in tumoral colon cell lines. |
| Q28509681 | Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine |
| Q35749862 | Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch. |
| Q36678039 | R-Spondin family members regulate the Wnt pathway by a common mechanism |
| Q34932642 | R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/beta-catenin pathway |
| Q24292884 | R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 |
| Q36997840 | RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function. |
| Q35670105 | RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells |
| Q37420042 | Rac1 drives intestinal stem cell proliferation and regeneration |
| Q39126564 | Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc |
| Q35534376 | Redox biology of the intestine |
| Q33643086 | Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis |
| Q36996297 | Regulation of metastasis in colorectal adenocarcinoma: a collision between development and tumor biology. |
| Q39617000 | Reinforcement of epithelial cell adhesion to basement membrane by a bacterial pathogen as a new infectious stratagem |
| Q37139984 | Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion |
| Q27305398 | Retracted: Multi-Level Interactions between the Nuclear Receptor TRα1 and the WNT Effectors β-Catenin/Tcf4 in the Intestinal Epithelium |
| Q53327324 | Risk of Intestinal Malignancy in Patients With Short Bowel Syndrome. |
| Q37012033 | Road for understanding cancer stem cells: model cell lines |
| Q36699327 | SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation |
| Q36301662 | Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development |
| Q34687656 | Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk. |
| Q33833613 | Small molecules and stem cells. Potency and lineage commitment: the new quest for the fountain of youth |
| Q42769371 | So many progenitors, so little myelin. |
| Q37655806 | Sphingolipids in colon cancer |
| Q24629901 | Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function |
| Q37192698 | Sphingosine-1-phosphate lyase in development and disease: sphingolipid metabolism takes flight |
| Q37477501 | Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines |
| Q38061121 | Stem cell therapy: an exercise in patience and prudence |
| Q36375720 | Stem cell-based growth, regeneration, and remodeling of the planarian intestine |
| Q30486086 | Stem cells and cell therapies in lung biology and lung diseases |
| Q28073597 | Stem cells and colorectal carcinogenesis |
| Q37508765 | Stem cells and solid cancers |
| Q36976592 | Stem cells as a potential future treatment of pediatric intestinal disorders |
| Q37799828 | Stem cells in gastrointestinal cancers: a matter of choice in cell fate determination |
| Q38203883 | Sweet and sour: the impact of differential glycosylation in cancer cells undergoing epithelial-mesenchymal transition |
| Q33664419 | Symplekin promotes tumorigenicity by up-regulating claudin-2 expression |
| Q33277113 | Systemic bud induction and retinoic acid signaling underlie whole body regeneration in the urochordate Botrylloides leachi |
| Q37923993 | T cell costimulation and coinhibition: genetics and disease. |
| Q34999356 | TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. |
| Q64074399 | TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer |
| Q39109832 | Targeting cancer stem cells for chemoprevention of pancreatic cancer. |
| Q79397666 | Targeting the Hedgehog pathway in cancer |
| Q30480629 | Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo |
| Q37679216 | The "Stars and Stripes" Metaphor for Animal Regeneration-Elucidating Two Fundamental Strategies along a Continuum |
| Q40309718 | The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes |
| Q35677720 | The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC. |
| Q34342516 | The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration |
| Q34313840 | The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis |
| Q34762033 | The Nlrp3 inflammasome: contributions to intestinal homeostasis |
| Q25256767 | The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear |
| Q38466771 | The Role of CD44 in Disease Pathophysiology and Targeted Treatment. |
| Q36501637 | The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment |
| Q28589724 | The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis |
| Q36674940 | The Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells |
| Q34071318 | The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways |
| Q35002372 | The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus). |
| Q52663264 | The adult Drosophila posterior midgut is maintained by pluripotent stem cells. |
| Q37013896 | The c-myc promoter: still MysterY and challenge |
| Q43677095 | The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters |
| Q34819259 | The effects of aging on stem cell behavior in Drosophila |
| Q28393062 | The effects of anthrax lethal toxin on host barrier function |
| Q29617793 | The extracellular matrix: a dynamic niche in cancer progression |
| Q38569328 | The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell |
| Q42459991 | The molecular pathogenesis of Barrett's esophagus: common signaling pathways in embryogenesis metaplasia and neoplasia |
| Q36241260 | The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer |
| Q56762984 | The role of the transcription factor AP-1 in colitis-associated and β-catenin-dependent intestinal tumorigenesis in mice |
| Q41758457 | The secreted Frizzled-Related Protein 2 modulates cell fate and the Wnt pathway in the murine intestinal epithelium |
| Q38773122 | The third dimension: new developments in cell culture models for colorectal research. |
| Q39339736 | The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells. |
| Q37526996 | Therapeutic implications of Cancer Initiating Cells |
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