Identification and characterization of human MUS81-MMS4 structure-specific endonuclease

scientific article

Identification and characterization of human MUS81-MMS4 structure-specific endonuclease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M302484200
P698PubMed publication ID12686547

P50authorAziz SancarQ15118973
P2093author name stringMüge Oğrünç
P2860cites workA human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphataseQ22008669
Purification and properties of human blue-light photoreceptor cryptochrome 2Q24297358
Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificitiesQ24534960
Conserved domains in DNA repair proteins and evolution of repair systemsQ24548678
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1Q24551095
ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologsQ24647834
Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonucleaseQ27935913
DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.Q27937263
MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiaeQ27939646
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathwayQ28141324
Human Mus81-associated endonuclease cleaves Holliday junctions in vitroQ28210371
The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motifQ28214697
Regulation of replication timing in fission yeastQ28363094
Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1Q28645598
Cell cycle checkpoints: preventing an identity crisisQ29547644
Cell cycle checkpoint signaling through the ATM and ATR kinasesQ29617837
The DNA replication checkpoint response stabilizes stalled replication forksQ29618306
DNA excision repairQ29618453
Mus81-Eme1 are essential components of a Holliday junction resolvaseQ29619843
Drosophila arginase is produced from a nonvital gene that contains the elav locus within its third intronQ30883568
Checkpoints: it takes more than time to heal some woundsQ34117424
CHK2 kinase--a busy messenger.Q34457165
Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formationQ34589920
The nonmutagenic repair of broken replication forks via recombinationQ35013053
Nucleotide excision repair in mammalian cellsQ41593250
A kinase from fission yeast responsible for blocking mitosis in S phaseQ48074342
Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4.Q53661726
A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filamentQ78882309
P433issue24
P407language of work or nameEnglishQ1860
P304page(s)21715-20
P577publication date2003-06-13
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification and characterization of human MUS81-MMS4 structure-specific endonuclease
P478volume278

Reverse relations

cites work (P2860)
Q37149779A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4.
Q27931208A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast.
Q38622583An Overview of the Molecular Mechanisms of Recombinational DNA Repair
Q58377015Comparative Genomics of Hemiascomycete Yeasts: Genes Involved in DNA Replication, Repair, and Recombination
Q39391040Control of Mus81 nuclease during the cell cycle
Q45107867Cooperation of the N-terminal Helicase and C-terminal endonuclease activities of Archaeal Hef protein in processing stalled replication forks
Q27650328Crystal structure of the Mus81-Eme1 complex
Q36487307DNA-damage repair; the good, the bad, and the ugly
Q35028557Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.
Q33925085Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis
Q30862224Efficient second strand cleavage during Holliday junction resolution by RuvC requires both increased junction flexibility and an exposed 5' phosphate
Q24644518Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells
Q37577441Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains
Q24537482Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells
Q26797303Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1
Q38245723Holliday junction resolvases
Q35559727Holliday junctions in the eukaryotic nucleus: resolution in sight?
Q36118209Isolation of quiescent and nonquiescent cells from yeast stationary-phase cultures
Q50287370MUS81 binds EME1, EME2
Q38996639MUS81-EME2 promotes replication fork restart
Q35910256Meiotic recombination intermediates and mismatch repair proteins
Q28266170Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
Q24684096Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae
Q35072858Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.
Q24627013RNA interference inhibition of Mus81 reduces mitotic recombination in human cells
Q48098663Resolvase OsGEN1 Mediates DNA Repair by Homologous Recombination.
Q42913266Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae
Q38293464Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
Q24298259Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
Q64075900Structure-Specific Endonucleases and the Resolution of Chromosome Underreplication
Q38593922Substrate specificity of the MUS81-EME2 structure selective endonuclease
Q35945625Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis.
Q35643073The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions
Q39113832The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A.
Q36099356The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice
Q46952804The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
Q38774142The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks