Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

scientific article

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.3755548
P3181OpenCitations bibliographic resource ID3228026
P698PubMed publication ID3755548

P2093author name stringE Chen
A Ullrich
L Rhee
M D Waterfield
T L Yang-Feng
U Francke
P J Parker
L Coussens
P433issue4766
P407language of work or nameEnglishQ1860
P921main subjectProtein kinase C gammaQ21114845
protein kinase C betaQ21114850
signal transductionQ828130
P304page(s)859-66
P577publication date1986-08-22
P1433published inScienceQ192864
P1476titleMultiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways
P478volume233

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cites work (P2860)
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Q33852435Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties
Q37141320Protein kinase C, an elusive therapeutic target?
Q50511731Protein kinase C-alpha mediates endothelial barrier dysfunction induced by TNF-alpha.
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Q72068105Protein kinase Cβ expression in melanoma cells and melanocytes: differential expression correlates with biological responses to 12-O-tetradecanoylphorbol 13-acetate
Q47679667Protein kinases in amphibian ectoderm induced for neural differentiation
Q48721148Purification and characterization of protein kinase C isozymes from rat heart
Q34634276Purification and characterization of three types of protein kinase C from rabbit brain cytosol
Q67672002Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: Individual response patterns and their relationships with both maturation and protein kinase C content
Q45033918Rapid filtration assays for protein kinase C activity and phorbol ester binding using multiwell plates with fitted filtration discs
Q40784189Real-Time Translocation and Function of PKCβII Isoform in Response to Nociceptive Signaling via the TRPV1 Pain Receptor
Q38316475Recent advances in receptor research
Q41509951Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line
Q41889651Regulation of GH3 pituitary tumour-cell adenylate cyclase activity by activators of protein kinase C
Q42799221Regulation of Na+-H+ exchange in normal NIH-3T3 cells and in NIH-3T3 cells expressing the ras oncogene
Q48268565Regulation of astrocyte proliferation by prostaglandin E2 and the alpha subtype of protein kinase C.
Q40641908Regulation of cytosolic phospholipase A(2) translocation
Q42800943Regulation of differentiation and protein kinase C expression in 3T3 T proadipocytes: effects of TGF-beta and transformation
Q39515158Regulation of protein kinase C activity by various lipids
Q36711217Regulation of protein kinase C activity in neuronal differentiation induced by the N-ras oncogene in PC-12 cells
Q48315224Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart
Q70998064Regulatory domain of human protein kinase C alpha dominantly inhibits protein kinase C beta-I-regulated growth and morphology in Saccharomyces cerevisiae
Q70174965Regulatory modulation in hepatology
Q43690861Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice
Q90043731Reticulocyte and red blood cell deformation triggers specific phosphorylation events
Q37462144Rice small C2-domain proteins are phosphorylated by calcium-dependent protein kinase.
Q40155730Roles of human peripheral blood leukocyte protein kinase C and G proteins in inflammatory mediator release by isogenic Escherichia coli strains
Q41700040Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells
Q34447989Selective translocation of protein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis
Q41836805Sequence conservation in the protein coding and intron regions of the engrailed transcription unit
Q40516059Sequence of human protein kinase C alpha
Q42820729Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase
Q40154363Signal transduction in human platelets and inflammatory mediator release induced by genetically cloned hemolysin-positive and -negative Escherichia coli strains
Q73564443Signal transduction mechanism in human neutrophil: comparative study between the zeta and beta-protein kinase isotypes
Q24303055Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
Q36708558Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy
Q36517697Specific protein kinase C isoforms as transducers and modulators of insulin signaling
Q34298292Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain
Q41773060Stimulation of phosphatidylcholine breakdown and diacylglycerol production by growth factors in Swiss-3T3 cells
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Q24674621The C2 domain calcium-binding motif: structural and functional diversity
Q24314678The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization
Q42577947The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate
Q36820567The Candida albicans PKC1 gene encodes a protein kinase C homolog necessary for cellular integrity but not dimorphism
Q40615747The Cytosolic Phospholipase A2 Catalytic Domain Modulates Association and Residence Time at Golgi Membranes
Q28361275The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin
Q48184498The common structure and activities of four subspecies of rat brain protein kinase C family
Q22254864The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus
Q42141639The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding
Q42799929The expression of PDGF-alpha but not PDGF-beta receptors is suppressed in Swiss/3T3 fibroblasts over-expressing protein kinase C-alpha
Q24530820The extended protein kinase C superfamily
Q34531291The gene coding for the p68 calcium-binding protein is localised to bands q32-q34 of human chromosome 5, and to mouse chromosome 11.
Q48098187The heterogeneity of protein kinase C in various rat tissues
Q35755645The influence of activation or inhibition of protein kinase C on the release of radioactivity from rat isolated atria labelled with [3H]-noradrenaline
Q69438027The interaction of aluminium with soluble protein kinase C from mouse brain
Q68315285The interleukin-4 receptor gene (IL4R) maps to 16p11.2–16p12.1 in human and to the distal region of mouse chromosome 7
Q29619947The molecular heterogeneity of protein kinase C and its implications for cellular regulation
Q38262070The molecular machinery of neurotransmitter release (Nobel lecture).
Q70163348The physical map of chromosome arm 19q: some new assignments, confirmations and re-assessments
Q24606883The protein kinase C-related PKC-L(eta) gene product is localized in the cell nucleus
Q41683869The regulatory domain of protein kinase C-epsilon restricts the catalytic-domain-specificity
Q41976770The role of hydrophobic interactions in the phospholipid-dependent activation of protein kinase C.
Q39557519The role of protein phosphorylation in the control of cell growth and differentiation
Q54647048The role of the phosphatidylinositol turnover in 12-hydroxyeicosatetraenoic acid generation from human platelets by Escherichia coli alpha-haemolysin, thrombin and fluoride.
Q28305776The rsp5-domain is shared by proteins of diverse functions
Q77483361The sevenfold way of PKC regulation
Q69445004The stimulation of phosphorylation of intracellular proteins in GH3 rat pituitary tumour cells by phorbol esters of distinct biological activity
Q43923507The transformed (initiated) human cell phenotype: study of cultured skin fibroblasts from individuals predisposed to cancer
Q37520009The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression
Q36531203Tissue and cellular distribution of the extended family of protein kinase C isoenzymes
Q38999244Toll-like receptor 2 activation by β2→1-fructans protects barrier function of T84 human intestinal epithelial cells in a chain length-dependent manner
Q24556556Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C
Q36745359Transcriptional regulation of the tartrate-resistant acid phosphatase (TRAP) gene by iron
Q42479307Translocation of protein kinase C isozymes in rat pituitary lactotroph-enriched cell cultures by substance P: effects of sex and age
Q36546242Transmitter release: target of regulation by protein kinase C?
Q42024338Two calcium-dependent protein kinases from Chlamydomonas reinhardtii are transcriptionally regulated by nutrient starvation
Q40872855Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.
Q24623403Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction
Q36417286Unique substrate specificity and regulatory properties of PKC-epsilon: a rationale for diversity
Q56987787Upregulation of PKC δ- and downregulation of PKC α-mRNA and protein by a phorbol ester in human T84 cells
Q49241259Vasoconstriction in rat isolated mesentery and small intestine in response to various activators of protein kinase C.
Q24563029WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome
Q35848808X-linked hypophosphataemia: a homologous phenotype in humans and mice with unusual organ-specific gene dosage
Q41994692Yeast phenotype classifies mammalian protein kinase C cDNA mutants
Q47827945ZmcPKC70, a protein kinase C-type enzyme from maize. Biochemical characterization, regulation by phorbol 12-myristate 13-acetate and its possible involvement in nitrate reductase gene expression
Q85478382[The molecular machinery of neurotransmitter secretion]
Q69364209cis-Fatty acids, which activate protein kinase C, attenuate Na+ and Ca2+ currents in mouse neuroblastoma cells