| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1012470381 |
| P356 | DOI | 10.1038/NATURE08787 |
| P8608 | Fatcat ID | release_lwod7u2v2bdinbgjvisa6tt46q |
| P3181 | OpenCitations bibliographic resource ID | 2333475 |
| P932 | PMC publication ID | 2877384 |
| P698 | PubMed publication ID | 20182505 |
| P5875 | ResearchGate publication ID | 41562716 |
| P50 | author | Kai Simons | Q880181 |
| Jonathan Weissman | Q6274745 | ||
| Ruedi Aebersold | Q7377799 | ||
| Christer S Ejsing | Q40356320 | ||
| Bernd Bodenmiller | Q88700613 | ||
| David K. Breslow | Q37381719 | ||
| Sean R Collins | Q37393509 | ||
| P2093 | author name string | Andrej Shevchenko | |
| P2860 | cites work | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease | Q22251069 |
| Is the mammalian serine palmitoyltransferase a high-molecular-mass complex? | Q24298593 | ||
| ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins | Q24300713 | ||
| Molecular machinery for non-vesicular trafficking of ceramide | Q24302195 | ||
| Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide | Q24337032 | ||
| Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER | Q24337469 | ||
| Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes | Q24632382 | ||
| Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants | Q24633806 | ||
| Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry | Q24646313 | ||
| Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL | Q24652984 | ||
| Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. | Q27930626 | ||
| Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression | Q27933027 | ||
| Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity | Q27934818 | ||
| Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function | Q38904716 | ||
| Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast | Q41833747 | ||
| Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma | Q43601724 | ||
| High-performance liquid chromatography analysis of molecular species of sphingolipid-related long chain bases and long chain base phosphates in Saccharomyces cerevisiae after derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate | Q43793900 | ||
| Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation | Q46703342 | ||
| Essential role for diacylglycerol in protein transport from the yeast Golgi complex. | Q48721596 | ||
| Status of childhood asthma in the United States, 1980-2007 | Q64132856 | ||
| Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile | Q27935813 | ||
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Q27938723 | ||
| The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant | Q27940195 | ||
| Principles of bioactive lipid signalling: lessons from sphingolipids | Q28265743 | ||
| A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications | Q28275529 | ||
| Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma | Q29614903 | ||
| Phosphate-binding tag, a new tool to visualize phosphorylated proteins | Q29617792 | ||
| In-gel digestion of proteins for MALDI-MS fingerprint mapping | Q33330016 | ||
| Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism | Q34202240 | ||
| Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function | Q34568452 | ||
| The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy | Q34594323 | ||
| Interorganelle trafficking of ceramide is regulated by phosphorylation-dependent cooperativity between the PH and START domains of CERT. | Q34620309 | ||
| ORMDL3 gene is associated with asthma in three ethnically diverse populations | Q34756865 | ||
| Effect of 17q21 variants and smoking exposure in early-onset asthma | Q34857209 | ||
| Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae | Q34920283 | ||
| Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network | Q34980423 | ||
| Functions and metabolism of sphingolipids in Saccharomyces cerevisiae | Q36491040 | ||
| Regulation of long chain unsaturated fatty acid synthesis in yeast | Q36571437 | ||
| Inhibitors of sphingolipid metabolism enzymes. | Q36627445 | ||
| Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling | Q36727413 | ||
| Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae | Q36768641 | ||
| The alliance of sphingosine-1-phosphate and its receptors in immunity | Q37010807 | ||
| Discovering susceptibility genes for asthma and allergy | Q37095239 | ||
| The role of sphingosine-1-phosphate and its receptors in asthma | Q37128721 | ||
| Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. | Q37230975 | ||
| SAC1 lipid phosphatase and growth control of the secretory pathway | Q37350551 | ||
| Protein quality control as a strategy for cellular regulation: lessons from ubiquitin-mediated regulation of the sterol pathway | Q37401243 | ||
| Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. | Q37408201 | ||
| Regulation of ceramide biosynthesis by TOR complex 2. | Q37439524 | ||
| The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation | Q38407684 | ||
| P433 | issue | 7284 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sphingolipids | Q410395 |
| ceramide metabolic process | Q14905116 | ||
| ORMDL sphingolipid biosynthesis regulator 2 | Q21124248 | ||
| SPOTS complex | Q21124249 | ||
| ORMDL sphingolipid biosynthesis regulator 3 | Q21124251 | ||
| ORMDL sphingolipid biosynthesis regulator 1 | Q21124253 | ||
| Serine palmitoyltransferase long chain base subunit 1 | Q21135688 | ||
| Serine C-palmitoyltransferase LCB2 YDR062W | Q27547563 | ||
| Phosphatidylinositol-3-phosphatase SAC1 YKL212W | Q27549612 | ||
| Sphingolipid homeostasis protein ORM2 YLR350W | Q27550500 | ||
| Sphingolipid homeostasis protein ORM1 YGR038W | Q27551947 | ||
| Serine C-palmitoyltransferase LCB1 YMR296C | Q27552599 | ||
| Tsc3p YBR058C-A | Q27552617 | ||
| P304 | page(s) | 1048-53 | |
| P577 | publication date | 2010-02-25 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Orm family proteins mediate sphingolipid homeostasis | |
| P478 | volume | 463 |
| Q37423775 | 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells |
| Q38156023 | 17q21 locus and ORMDL3: an increased risk for childhood asthma |
| Q35912807 | A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses |
| Q45950081 | A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast. |
| Q50144971 | A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle. |
| Q89581354 | A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels |
| Q34714955 | A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. |
| Q97643148 | A global lipid map defines a network essential for Zika virus replication |
| Q28293885 | A large-scale, consortium-based genomewide association study of asthma |
| Q34955765 | A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. |
| Q64041127 | A perilous path: the inborn errors of sphingolipid metabolism |
| Q34974977 | A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children. |
| Q38002318 | A world of sphingolipids and glycolipids in the brain--novel functions of simple lipids modified with glucose |
| Q36113177 | Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice |
| Q42725909 | Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether. |
| Q35747758 | Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells |
| Q35096324 | Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions |
| Q36348432 | Airway reactivity and sphingolipids-implications for childhood asthma |
| Q35035158 | All-trans retinoic acid modulates ORMDL3 expression via transcriptional regulation |
| Q37576605 | An inducible ER-Golgi tether facilitates ceramide transport to alleviate lipotoxicity |
| Q34402916 | An update on sphingosine-1-phosphate and other sphingolipid mediators |
| Q35045437 | Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data |
| Q86699416 | Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity |
| Q51735705 | Aryl hydrocarbon receptor signaling promotes ORMDL3-dependent generation of sphingosine-1-phosphate by inhibiting sphingosine-1-phosphate lyase. |
| Q38485516 | Assessment of crosstalks between the Snf1 kinase complex and sphingolipid metabolism in S. cerevisiae via systems biology approaches |
| Q58862200 | Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma |
| Q41041515 | Association between ORMDL3 polymorphism and susceptibility to asthma: a meta-analysis. |
| Q47890784 | Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes. |
| Q34045396 | Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population |
| Q64088374 | Asthma and obesity in the Middle East region: An overview |
| Q35225431 | Autophagy in the light of sphingolipid metabolism |
| Q47329636 | Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling. |
| Q38098434 | Biotechnological production of sphingoid bases and their applications. |
| Q50144888 | Can Controlling Endoplasmic Reticulum Dysfunction Treat Allergic Inflammation in Severe Asthma With Fungal Sensitization? |
| Q47172594 | Cell Size and Growth Rate Are Modulated by TORC2-Dependent Signals |
| Q43150780 | Cell biology: A brake on lipid synthesis. |
| Q64071005 | Ceramide Imbalance and Impaired TLR4-Mediated Autophagy in BMDM of an ORMDL3-Overexpressing Mouse Model |
| Q55002300 | Ceramide species are elevated in human breast cancer and are associated with less aggressiveness. |
| Q34729966 | Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models |
| Q42621345 | Characterization of a novel isoform of the human ORMDL3 gene |
| Q33557346 | Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. |
| Q41716771 | Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact. |
| Q58554422 | Chronic Psychosocial Stress in Mice Is Associated With Increased Acid Sphingomyelinase Activity in Liver and Serum and With Hepatic C16:0-Ceramide Accumulation |
| Q37158874 | Constructing de novo biosynthetic pathways for chemical synthesis inside living cells |
| Q35573342 | Control of Plasma Membrane Permeability by ABC Transporters. |
| Q38927559 | Coordinated regulation of the orosomucoid-like gene family expression controls de novo ceramide synthesis in mammalian cells. |
| Q44169090 | Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. |
| Q92587636 | Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes |
| Q46588935 | Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides |
| Q97565947 | Differential Expression of Ormdl Genes in the Islets of Mice and Humans with Obesity |
| Q27317139 | Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans |
| Q48046142 | Disruption of sphingolipid biosynthesis in Nicotiana benthamiana activates salicylic acid-dependent responses and compromises resistance to Alternaria alternata f. sp. lycopersici. |
| Q90146842 | Downregulation of orosomucoid 2 acts as a prognostic factor associated with cancer-promoting pathways in liver cancer |
| Q48221250 | Dysregulation of metabolic pathways in a mouse model of allergic asthma |
| Q46276341 | Easy, Fast, and Reproducible Quantification of Cholesterol and Other Lipids in Human Plasma by Combined High Resolution MSX and FTMS Analysis |
| Q40766329 | Effect of Gubenfangxiao decoction on respiratory syncytial virus-induced asthma and expression of asthma susceptibility gene orosomucoid 1-like protein 3 in mice. |
| Q57179424 | Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze |
| Q47678283 | Effects of genetic factors to inhaled corticosteroid response in children with asthma: a literature review |
| Q26825586 | Endoplasmic reticulum stress and inflammation |
| Q55279398 | Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation. |
| Q92333939 | Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism |
| Q36373921 | Ethylene Modulates Sphingolipid Synthesis in Arabidopsis |
| Q34801792 | Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells |
| Q34073801 | Expression of the bacterial type III effector DspA/E in Saccharomyces cerevisiae down-regulates the sphingolipid biosynthetic pathway leading to growth arrest. |
| Q36438411 | Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance |
| Q21134862 | Flexibility of a eukaryotic lipidome--insights from yeast lipidomics |
| Q36843274 | Following the flux of long-chain bases through the sphingolipid pathway in vivo using mass spectrometry |
| Q28709421 | Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions |
| Q57170220 | Gene editing in the context of an increasingly complex genome |
| Q43039948 | Gene expression patterns in livers of Hispanic patients infected with hepatitis C virus |
| Q35214374 | Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis |
| Q40138527 | Genetic variants and risk of asthma in an American Indian population |
| Q36808724 | Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network |
| Q43525026 | Genetic variants of 17q21 are associated with childhood-onset asthma and related phenotypes in a northeastern Han Chinese population: a case-control study |
| Q43450626 | Genetic variants on 17q21 are associated with ankylosing spondylitis susceptibility and severity in a Chinese Han population |
| Q37833146 | Genome-wide association studies for discovery of genes involved in asthma |
| Q64086691 | Genomic, Transcriptomic, and Epigenomic Features Differentiate Genes That Are Relevant for Muscular Polyunsaturated Fatty Acids in the Common Carp |
| Q36405917 | Glycosphingolipids and cell death: one aim, many ways |
| Q30382642 | HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship. |
| Q37027169 | Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2. |
| Q54978902 | Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae. |
| Q35134904 | High-content screening of yeast mutant libraries by shotgun lipidomics |
| Q54542484 | High-level production of tetraacetyl phytosphingosine (TAPS) by combined genetic engineering of sphingoid base biosynthesis and L-serine availability in the non-conventional yeast Pichia ciferrii. |
| Q26741039 | Homeoviscous Adaptation and the Regulation of Membrane Lipids |
| Q39089127 | Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling. |
| Q36154956 | Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin and Nigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes. |
| Q33767342 | Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis |
| Q60915327 | Identifying genes with tri-modal association with survival and tumor grade in cancer patients |
| Q50969955 | Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity. |
| Q37881286 | Inhalant allergies in children |
| Q47990488 | Inositol Depletion Induced by Acute Treatment of the Bipolar Disorder Drug Valproate Increases Levels of Phytosphingosine |
| Q36881382 | Inositol lipid regulation of lipid transfer in specialized membrane domains. |
| Q64258063 | Integrated Proteomics and Metabolomic Analyses of Plasma Injury Biomarkers in a Serious Brain Trauma Model in Rats |
| Q44678974 | Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma |
| Q34053079 | Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate |
| Q38821886 | Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsiveness |
| Q92581865 | Investigating the regulatory role of ORMDL3 in airway barrier dysfunction using in vivo and in vitro models |
| Q26860280 | Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome |
| Q33778298 | Keeping sphingolipid levels nORMal |
| Q35145403 | Kinetochore genes are required to fully activate secretory pathway expansion in S. cerevisiae under induced ER stress |
| Q35138292 | Lipid Analysis of Airway Epithelial Cells for Studying Respiratory Diseases |
| Q28276574 | Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets |
| Q38217765 | Lipid landscapes and pipelines in membrane homeostasis |
| Q37187327 | Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition |
| Q38151973 | Lipids and cell death in yeast |
| Q47108131 | Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis |
| Q27930217 | Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase |
| Q27930785 | Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation |
| Q49166378 | MCC/Eisosomes Regulate Cell Wall Synthesis and Stress Responses in Fungi. |
| Q41755967 | Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis |
| Q36454387 | Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups |
| Q37618072 | Membrane engineering of S. cerevisiae targeting sphingolipid metabolism |
| Q36266173 | Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins |
| Q34330398 | Membranes in balance: mechanisms of sphingolipid homeostasis |
| Q54407970 | Microarray analysis of hepatic gene expression in juvenile Japanese flounder Paralichthys olivaceus fed diets supplemented with fish or vegetable oils. |
| Q89479913 | Modulation of TORC2 Signaling by a Conserved Lkb1 Signaling Axis in Budding Yeast |
| Q38287558 | Molecular mechanisms of nasal epithelium in rhinitis and rhinosinusitis |
| Q24301846 | Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I |
| Q40500249 | Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells |
| Q27315147 | Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure |
| Q38457018 | Nonlinear fitness consequences of variation in expression level of a eukaryotic gene |
| Q35079758 | Novel HSAN1 mutation in serine palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity |
| Q92820037 | Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages |
| Q50500056 | ORM Elevation in Response to Cognitive Impairment Is an Accompanying Phenomenon. |
| Q48120556 | ORM Expression Alters Sphingolipid Homeostasis and Differentially Affects Ceramide Synthase Activity |
| Q35229446 | ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy |
| Q42159911 | ORMDL proteins regulate ceramide levels during sterile inflammation |
| Q28118152 | ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis |
| Q48024260 | ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway |
| Q92382053 | ORMDL3 and allergic asthma: From physiology to pathology |
| Q24299559 | ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6 |
| Q30573228 | ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48. |
| Q38682191 | ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma |
| Q36030524 | Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways |
| Q43092058 | Orm proteins integrate multiple signals to maintain sphingolipid homeostasis |
| Q46166735 | Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide |
| Q40421305 | Orosomucoid Proteins Interact with the Small Subunit of Serine Palmitoyltransferase and Contribute to Sphingolipid Homeostasis and Stress Responses in Arabidopsis. |
| Q38364856 | Orosomucoid, an acute response protein with multiple modulating activities |
| Q46229658 | Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma |
| Q37895205 | PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism |
| Q36579422 | Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages |
| Q37980790 | Perspectives on immunomodulation early in life. |
| Q38109881 | Phosphatidylinositol-4-phosphate: the Golgi and beyond |
| Q27304793 | Phosphoinositide kinase signaling controls ER-PM cross-talk. |
| Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
| Q40956422 | PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles |
| Q38792251 | Plant Sphingolipid Metabolism and Function |
| Q38810193 | Plant sphingolipids: Their importance in cellular organization and adaption. |
| Q35596158 | Plasma Membrane Proteolipid 3 Protein Modulates Amphotericin B Resistance through Sphingolipid Biosynthetic Pathway. |
| Q38752381 | Plasma membrane organization promotes virulence of the human fungal pathogen Candida albicans |
| Q38034862 | Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae |
| Q54517310 | Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. |
| Q34663879 | Promoter characterization and role of cAMP/PKA/CREB in the basal transcription of the mouse ORMDL3 gene |
| Q96952221 | Proper regulation of inositolphosphorylceramide levels is required for acquirement of low pH resistance in budding yeast |
| Q47107227 | Proposal for a common nomenclature for fragment ions in mass spectra of lipids. |
| Q51738049 | Protection mechanisms against aberrant metabolism of sphingolipids in budding yeast. |
| Q46246140 | Protective role of the HOG pathway against the growth defect caused by impaired biosynthesis of complex sphingolipids in yeast Saccharomyces cerevisiae. |
| Q35042863 | Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry |
| Q27934330 | Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae |
| Q38385271 | Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion. |
| Q28118990 | PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity |
| Q33634444 | Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease. |
| Q47722430 | Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeast Saccharomyces cerevisiae |
| Q34986547 | RNA-seq analysis of broiler liver transcriptome reveals novel responses to high ambient temperature |
| Q38868037 | Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells |
| Q27933657 | Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1 |
| Q35121224 | Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in Saccharomyces cerevisiae |
| Q35116189 | Regulation of lipid metabolism: a tale of two yeasts |
| Q36058716 | Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast |
| Q38711466 | Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein |
| Q38262594 | Resveratrol and its oligomers: modulation of sphingolipid metabolism and signaling in disease |
| Q34142159 | Rice ORMDL controls sphingolipid homeostasis affecting fertility resulting from abnormal pollen development |
| Q34920713 | Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus |
| Q92210473 | Role of MCC/Eisosome in Fungal Lipid Homeostasis |
| Q34180063 | Role of a conserved arginine residue during catalysis in serine palmitoyltransferase |
| Q37826774 | Roles of sphingolipids in Drosophila development and disease |
| Q35080312 | Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids |
| Q35048834 | Rule-based models of the interplay between genetic and environmental factors in childhood allergy |
| Q38869085 | S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis |
| Q36333335 | Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated |
| Q90596984 | Seipin negatively regulates sphingolipid production at the ER-LD contact site |
| Q24323001 | Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression |
| Q35006511 | Signaling at the Golgi |
| Q35842051 | Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability |
| Q38937414 | Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. |
| Q35324757 | Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics |
| Q64146866 | Sphingolipid biosynthesis in man and microbes |
| Q27932351 | Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress |
| Q50130199 | Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function. |
| Q38094869 | Sphingolipid homeostasis in the endoplasmic reticulum and beyond |
| Q48156182 | Sphingolipid metabolic flow controls phosphoinositide turnover at the trans-Golgi network |
| Q49950035 | Sphingolipid metabolism in cancer signalling and therapy. |
| Q35061720 | Sphingolipid metabolites in inflammatory disease |
| Q26992148 | Sphingolipid signaling in metabolic disorders |
| Q40689643 | Sphingolipid signaling mediates iron toxicity |
| Q47742080 | Sphingolipids activate the endoplasmic reticulum stress surveillance pathway. |
| Q30467364 | Sphingolipids and plant defense/disease: the "death" connection and beyond |
| Q28084945 | Sphingolipids as cell fate regulators in lung development and disease |
| Q37340289 | Sphingolipids contribute to acetic acid resistance in Zygosaccharomyces bailii. |
| Q40867505 | Sphingolipids regulate telomere clustering by affecting the transcription of genes involved in telomere homeostasis |
| Q42575213 | Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons |
| Q55267154 | Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study. |
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