Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

scientific article

Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1035670321
P356DOI10.1038/377744A0
P3181OpenCitations bibliographic resource ID3836262
P698PubMed publication ID7477266

P50authorBrian KobilkaQ80907
P2093author name stringG S Barsh
V J Dzau
R E Pratt
L Hein
P2860cites workHuman type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lungQ28117226
Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptorQ28283897
Assignment of the human angiotensin II type 2 receptor gene (AGTR2) to chromosome Xq22-q23 by fluorescence in situ hybridizationQ28303792
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant miceQ28591400
Derivation of completely cell culture-derived mice from early-passage embryonic stem cellsQ29547491
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Expression of AT2 receptors in the developing rat fetusQ34198676
Balloon angioplasty enhances the expression of angiotensin II AT1 receptors in neointima of rat aortaQ35608044
Cloning of cDNA and analysis of the gene for mouse angiotensin II type 2 receptorQ36758429
Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarctionQ40341321
Brain angiotensin receptor subtypes in the control of physiological and behavioral responsesQ40746499
A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitroQ43991339
Effect of nonpeptide angiotensin receptor antagonists on water intake and salt appetite in ratsQ46387761
Expression of AT2 receptors in rat fetal subdermal cellsQ46688960
Effects of angiotensin II on [3H]noradrenaline release and phosphatidylinositol hydrolysis in the parietal cortex and locus coeruleus of the rat.Q48186533
Brain angiotensin AT-2 receptor antagonism and water intakeQ48382079
The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking and vasopressin responses to central angiotensinQ48454168
Analysis of angiotensin II receptor subtypes in individual rat brain nucleiQ48485326
Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts.Q54197875
Non-injection methods for the production of embryonic stem cell-embryo chimaerasQ59092151
Drinking induced by subcutaneous injection of angiotensin II in the rat is blocked by the selective AT1 receptor antagonist DuP 753 but not by the selective AT2 receptor antagonist WL 19Q60054757
Angiotensin II binding sites in the rat fetus: characterization of receptor subtypes and interaction with guanyl nucleotidesQ70651999
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in ratsQ72782190
P2507corrigendum / erratumErratum: Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in miceQ60079823
P433issue6551
P407language of work or nameEnglishQ1860
P921main subjectcirculatory systemQ11068
regulation of blood pressureQ14819786
Angiotensin II receptor type 2Q21113831
P304page(s)744-7
P577publication date1995-10-26
P1433published inNatureQ180445
P1476titleBehavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice
P478volume377

Reverse relations

cites work (P2860)
Q40130491A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.
Q47323334A Cre-loxP solution for defining the brain renin-angiotensin system. Focus on "Targeted viral delivery of Cre recombinase induces conditional gene deletion in cardiovascular circuits of the mouse brain".
Q48667990A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex
Q30434317ANG II type 2 receptor regulates smooth muscle growth and force generation in late fetal mouse development
Q42669920AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.
Q42014112AT(2) receptor-dependent vasodilation is mediated by activation of vascular kinin generation under flow conditions
Q43800030AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction
Q44555026AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain
Q30275852AT2 Receptors: Potential Therapeutic Targets for Hypertension
Q26829592AT2 receptor activities and pathophysiological implications
Q37821128AT2 receptor signaling and sympathetic regulation
Q35047332AT2 receptor-mediated vasodilatation is unmasked by AT1 receptor blockade in conscious SHR.
Q41819451AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activation
Q38208962AT2 receptors targeting cardiac protection post-myocardial infarction
Q37274124AT2 receptors: functional relevance in cardiovascular disease.
Q34518023AVR/NAVR deficiency lowers blood pressure and differentially affects urinary concentrating ability, cognition, and anxiety-like behavior in male and female mice
Q30470062Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme
Q73544827Activation of local renin-angiotensin system by chronic hypoxia in rat pancreas
Q34126751Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).
Q37598488Adapter proteins and promoter regulation of the angiotensin AT2 receptor--implications for cardiac pathophysiology
Q77718867Adrenal angiotensin II type 1 and type 2 receptors in Cushing's and Conn's syndromes
Q83467008Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells
Q54017975Analysis of responses to angiotensin II in the mouse.
Q40639731AngII induces transient phospholipase D activity in the H295R glomerulosa cell model.
Q34558572Angiotensin AT2 receptor ligands: do they have potential as future treatments for neurological disease?
Q35045801Angiotensin AT2 receptors: cardiovascular hope or hype?
Q48106483Angiotensin II AT2 Receptors Contribute to Regulate the Sympathoadrenal and Hormonal Reaction to Stress Stimuli.
Q60682871Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
Q53482343Angiotensin II Type 2 Receptor Inhibits Vascular Intimal Proliferation With Activation of PPARγ.
Q51454283Angiotensin II and III suppress food intake via angiotensin AT(2) receptor and prostaglandin EP(4) receptor in mice.
Q28577645Angiotensin II and NGF differentially influence microtubule proteins in PC12W cells: role of the AT2 receptor
Q34064179Angiotensin II and calcium channels
Q43797608Angiotensin II in cardiac pressure-overload hypertrophy in fetal sheep
Q48311566Angiotensin II in central nervous system physiology
Q45049892Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors
Q78207338Angiotensin II is a growth factor in the peri-implantation rat embryo
Q74265524Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form
Q44692644Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes
Q38167346Angiotensin II receptor antagonists in acute coronary syndromes
Q34622302Angiotensin II receptor antagonists role in arterial hypertension
Q41623699Angiotensin II receptors in endothelial cells
Q48292966Angiotensin II receptors in the human brain
Q28346704Angiotensin II reduces infarct size and has no effect on post-ischaemic contractile dysfunction in isolated rat hearts
Q57630567Angiotensin II signal transduction pathways
Q42155832Angiotensin II signaling up-regulates the immediate early transcription factor ATF3 in the left but not the right atrium
Q44904447Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor
Q46103013Angiotensin II subtype 2 receptor blockade and deficiency attenuate the development of atherosclerosis in an apolipoprotein E-deficient mouse model of diabetes.
Q37986143Angiotensin II type 2 receptor agonists: where should they be applied?
Q51825386Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
Q40851849Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation
Q48287984Angiotensin II type 2 receptor signaling affects dopamine levels in the brain and prevents binge eating disorder
Q74023758Angiotensin II type 2 receptor stimulation of neuronal delayed-rectifier potassium current involves phospholipase A2 and arachidonic acid
Q36081206Angiotensin II type 2 receptor-mediated vasodilation. Focus on bradykinin, NO and endothelium-derived hyperpolarizing factor(s).
Q37340136Angiotensin II type 2 receptors have a major somatodendritic distribution in vasopressin-containing neurons in the mouse hypothalamic paraventricular nucleus
Q42987208Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase
Q37339329Angiotensin II type-2 receptor-specific effects on the cardiovascular system
Q35971305Angiotensin II, a Neuropeptide at the Frontier between Endocrinology and Neuroscience: Is There a Link between the Angiotensin II Type 2 Receptor and Alzheimer's Disease?
Q77943856Angiotensin II: a reproductive hormone too?
Q34268762Angiotensin and its AT2 receptor: new insights into an old system
Q73579468Angiotensin receptor subtypes in the uterine artery during ovine pregnancy
Q30585823Angiotensin receptor type 2 activation induces neuroprotection and neurogenesis after traumatic brain injury
Q41746684Angiotensin receptors and norepinephrine neuromodulation: implications of functional coupling
Q47885872Angiotensin receptors and norepinephrine neuromodulation: implications of functional coupling
Q28284938Angiotensin receptors in the nervous system
Q33687045Angiotensin receptors: molecular biology and signalling
Q38275879Angiotensin type 1 and type 2 receptors during ontogeny: cardiovascular and renal effects
Q37271037Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-γ.
Q47768368Angiotensin-converting enzyme 2 protects from severe acute lung failure
Q35927004Angiotensin-converting enzyme and male fertility
Q73001313Assessment of atrioventricular nodal physiology in the mouse
Q27346365Attenuation of ligand-induced activation of angiotensin II type 1 receptor signaling by the type 2 receptor via protein kinase C.
Q40860075Behavior in mice with targeted disruption of single genes
Q42442933Behavioural performance in three substrains of mouse strain 129.
Q37853834Blood pressure and renal hemodynamic effects of angiotensin fragments
Q37127331Brain renin angiotensin in disease
Q82768839C3123A polymorphism of the angiotensin II type 2 receptor gene and salt sensitivity in healthy Japanese men
Q24605567Cancer cachexia--pathophysiology and management
Q35188971Candidate Agtr2 influenced genes and pathways identified by expression profiling in the developing brain of Agtr2(-/y) mice
Q28505671Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects
Q47316917Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice.
Q48835664Cardiovascular ATIP (Angiotensin receptor type 2 interacting protein) expression in mouse development
Q44573472Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Q37377636Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxants
Q45154803Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus
Q44851212Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats
Q47962393Chemical lesion of the inferior olive reduces [125I]sarcosine1-angiotensin II binding to AT2 receptors in the cerebellar cortex of young rats
Q37360830Chimeric mice carrying 'regional' targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells
Q43607896Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons
Q77486593Circadian rhythms of activity and drinking in mice lacking angiotensin II 1A receptors
Q40667685Circulating microparticles from diabetic rats impair endothelial function and regulate endothelial protein expression.
Q34065655Classical Renin-Angiotensin system in kidney physiology
Q35125556Comparison of the transcriptomes of mouse skin derived precursors (SKPs) and SKP-derived fibroblasts (SFBs) by RNA-Seq
Q37365115Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes
Q43253857Compound 21, the first orally active, selective agonist of the angiotensin type 2 receptor (AT2): implications for AT2 receptor research and therapeutic potential
Q92710285Counter-regulatory renin-angiotensin system in cardiovascular disease
Q89394623Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
Q34162513Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells
Q37136352Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling
Q34557839Developmental changes in AT1 and AT2 receptor-protein expression in rats
Q45239069Developmental expression patterns for angiotensin receptors in mouse skin and brain
Q35063290Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface
Q38079544Different cross-talk sites between the renin-angiotensin and the kallikrein-kinin systems
Q48655552Differential action of AGCF2 upon cell type-dependent expression of human angiotensinogen gene
Q28569728Differential effects of 17beta-estradiol and of synthetic progestins on aldosterone-salt-induced kidney disease
Q42273452Differential role of angiotensin II receptor subtypes on endothelial superoxide formation
Q44542218Differential vasoconstrictions induced by angiotensin II: role of AT1 and AT2 receptors in isolated C57BL/6J mouse blood vessels.
Q48522887Distribution of angiotensin type-1 receptor messenger RNA expression in the adult rat brain
Q47617969Dose-dependent inhibitory effects of angiotensin II on visual responses of the rat superior colliculus: AT1 and AT2 receptor contributions
Q93178810Downregulation of AT2R decreases the responsiveness of BKCa channels to angiotensin II in patients with hypertension
Q35782663Early expression of all the components of the renin-angiotensin-system in human development
Q44390736Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats
Q43967973Effect of angiotensin II on pulse wave velocity in humans is mediated through angiotensin II type 1 (AT(1)) receptors
Q73098656Effect of cortisol on fetal ovine vascular angiotensin II receptors and contractility
Q74450181Effects of ACTH on adrenal angiotensin II receptor subtype expression in vivo
Q48269962Effects of targeted disruption of the mouse angiotensin II type 2 receptor gene on stress-induced hyperthermia
Q73064446Effects of the insurmountable angiotensin AT1 receptor antagonist candesartan and the surmountable antagonist losartan on ischemia/reperfusion injury in rat hearts
Q28283897Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor
Q42993543Efficient transcription of the human angiotensin II type 2 receptor gene requires intronic sequence elements
Q44838500Elevated blood pressure in normotensive rats produced by 'knockdown' of the angiotensin type 2 receptor
Q33894083Elevated testosterone levels during rat pregnancy cause hypersensitivity to angiotensin II and attenuation of endothelium-dependent vasodilation in uterine arteries
Q28506779Embryonic lethality in Dear gene-deficient mice: new player in angiogenesis
Q43263750Endothelial AT(2)-receptors: chicken or egg?
Q35850581Exploring type I angiotensin (AT1) receptor functions through gene targeting.
Q24563508Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth
Q44512040Function of renal angiotensin AT2 receptors is not enhanced in Lyon hypertensive rats
Q38340269G protein-coupled receptors: functional and mechanistic insights through altered gene expression
Q35839992Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice
Q40861559Gene disruption in mice: models of development and disease
Q40892446Gene targeting--homing in on alpha 2-adrenoceptor-subtype function
Q35176920Gene-targeting studies of the renin-angiotensin system: mechanisms of hypertension and cardiovascular disease
Q48813717Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist
Q48861743Genetic deletion of angiotensin AT2 receptor leads to increased cell numbers in different brain structures of mice
Q79105221Genetic disorders of human congenital anomalies of the kidney and urinary tract (CAKUT)
Q35179025Genetic evaluation for coronary artery disease
Q37871869Genetically modified mouse models used for studying the role of the AT2 receptor in cardiac hypertrophy and heart failure
Q47279404Haplotypes of the angiotensin II receptor genes AGTR1 and AGTR2 in women with normotensive pregnancy and women with preeclampsia
Q41953838High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats
Q38069825How does angiotensin AT(2) receptor activation help neuronal differentiation and improve neuronal pathological situations?
Q44249518Identification of the region of AT2 receptor needed for inhibition of the AT1 receptor-mediated inositol 1,4,5-triphosphate generation
Q44642393Identification of two AGTR2 mutations in male patients with non-syndromic mental retardation.
Q36354009Impact of AT2 receptor deficiency on postnatal cardiovascular development
Q37416298Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure
Q51892892Impaired spatial memory and altered dendritic spine morphology in angiotensin II type 2 receptor-deficient mice.
Q45294803Importance of the renin-angiotensin system in the regulation of arterial blood pressure in conscious mice and rats
Q78050736In-vivo electrophysiological study in mice with chronic anterior myocardial infarction
Q43766131Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice
Q37461915Increased angiotensin II AT1 receptor mRNA and binding in spleen and lung of AT2 receptor gene disrupted mice
Q52010170Increased maternal cortisol in late-gestation ewes decreases fetal cardiac expression of 11beta-HSD2 mRNA and the ratio of AT1 to AT2 receptor mRNA.
Q57630554Insights derived from ACE knockout mice
Q35850538Insights into angiotensin II receptor function through AT2 receptor knockout mice
Q33987660Insights into the functions of type 1 (AT1) angiotensin II receptors provided by gene targeting
Q48061654Insulin and insulin-like growth factors induce expression of angiotensin type-2 receptor in vascular-smooth-muscle cells
Q78229164Interactions between AT1 and AT2 receptors in uterine arteries from pregnant ewes
Q36241932International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].
Q52937062Intronic ANG II type 2 receptor gene polymorphism 1675 G/A modulates receptor protein expression but not mRNA splicing.
Q38061004Key developments in renin-angiotensin-aldosterone system inhibition.
Q34140879Knockout of renin-angiotensin system genes: effects on vascular development
Q35912250Lifestyle intervention might easily improve blood pressure in hypertensive men with the C genotype of angiotensin II type 2 receptor gene
Q34731369Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis
Q73318406Lipopolysaccharides and cytokines downregulate the angiotensin II type 2 receptor in rat cardiac fibroblasts
Q37308105Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog.
Q48705203Localization of angiotensin-converting enzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus
Q37981089Long-term blood pressure control: is there a set-point in the brain?
Q46047739Maternal adaptation in pregnant hypertensive rats: improvement of vascular and inflammatory variables and oxidative damage in the kidney.
Q48493960Maternal nutrient restriction in sheep: hypertension and decreased nephron number in offspring at 9 months of age.
Q30306044Mechanism of action of angiotensin-receptor blocking agents
Q51471225Mechanisms of impaired urinary concentrating ability in adult rats treated neonatally with enalapril.
Q30843430Microvascular vasodilator properties of the angiotensin II type 2 receptor in a mouse model of type 1 diabetes
Q52170561Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension.
Q48672854Modulation of angiotensin II type 2 receptor mRNA in rat hypothalamus and brainstem neuronal cultures by growth factors.
Q45147849Modulation of body fluids and angiotensin II receptors in a rat model of intra-uterine growth restriction
Q34613050Molecular and phenotypic analysis of Attractin mutant mice
Q41084357Molecular biology of angiotensin receptors and their role in human cardiovascular disease
Q36062244Molecular evidence of tissue renin-angiotensin systems: a focus on the brain
Q34140872Mouse models of blood pressure regulation and hypertension
Q37828217Mouse systems for studying the genetics of hypertension and related disorders
Q28592947Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes
Q48564719Mutation of a conserved fifth transmembrane domain lysine residue (Lys215) attenuates ligand binding in the angiotensin II type 2 receptor
Q47734837Neuronal ion channel signalling pathways: modulation by angiotensin II.
Q35079395New approaches to genetic manipulation of mice: tissue-specific expression of ACE.
Q37809435New insights into angiotensin receptor actions: from blood pressure to aging
Q52525698Normotensive blood pressure in mice with a disrupted renin Ren-1d gene.
Q52184810Ontogeny and regulation of cardiac angiotensin types 1 and 2 receptors during fetal life in sheep.
Q60274922Ontogeny of angiotensin II receptors, types 1 and 2, in ovine mesonephros and metanephros
Q36296584Ontogeny of angiotensin type 2 and type 1 receptor expression in mice
Q52099641Ontogeny of congenital anomalies of the kidney and urinary tract, CAKUT
Q41971058Opposite effects of angiotensins receptors type 2 and type 4 on streptozotocin induced diabetes vascular alterations in mice
Q49053455Opposite regulation of brain angiotensin type 1 and type 2 receptors in cold-induced hypertension
Q59868686Oral administration of losartan influences aminopeptidase activity in the frontal cortex
Q34289976Origin, differentiation and regulation of fetal and adult Leydig cells
Q31115399PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism
Q42544169Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat.
Q37452264Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice
Q28279771Physiology of kidney renin
Q85690746Platelet-endothelial cell interaction in brain microvessels of angiotensin II type-2 receptor knockout mice following transient bilateral common carotid artery occlusion
Q45713726Podocytes of AT2 receptor knockout mice are protected from angiotensin II-mediated RAGE induction
Q35074218Possible involvement of the adipose tissue renin-angiotensin system in the pathophysiology of obesity and obesity-related disorders.
Q28379250Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole
Q38083849Postnatal development of the renal medulla; role of the renin-angiotensin system
Q42503774Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
Q77493413Presence of angiotensin II and expression of angiotensin II type-2 receptor in human fallopian tube
Q35173127Pressor responsiveness to angiotensin II in female mice is enhanced with age: role of the angiotensin type 2 receptor.
Q77104362Prostanoids, but not nitric oxide, counterregulate angiotensin II mediated vasoconstriction in vivo
Q39294782Protective Angiotensin Type 2 Receptors in the Brain and Hypertension
Q41820888Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats
Q39862510Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor
Q27023787Rational drug design and synthesis of molecules targeting the angiotensin II type 1 and type 2 receptors
Q34260674Recent advances involving the renin-angiotensin system
Q33418273Receptor-induced dilatation in the systemic and intrarenal adaptation to pregnancy in rats
Q33593068Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
Q50665394Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis.
Q35782695Renin angiotensin system in development of mice and men
Q34555338Renin enhancer is critical for control of renin gene expression and cardiovascular function.
Q37269647Renin-angiotensin system revisited
Q33658583Renin-angiotensin systems and reproduction
Q35656144Reporter mouse strain provides a novel look at angiotensin type-2 receptor distribution in the central nervous system
Q39091986Review: AT1-receptors in the central nervous system
Q39091996Review: Gene targeting studies of angiotensin II type 1 (AT1) receptors
Q39091992Review: Lessons on renal function from transgenic mice lacking different angiotensin II receptors
Q51432835Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.
Q44185525Role of AT2 receptor in the brain in regulation of blood pressure and water intake
Q35608848Role of angiotensin AT1 and AT2 receptors in cardiac hypertrophy and cardiac remodelling
Q33883065Role of angiotensin AT1, and AT2 receptors in cardiac hypertrophy and disease
Q37284634Role of mitogen-activated protein kinase in cardiac hypertrophy and heart failure
Q43708511Role of the renin-angiotensin system during alterations of sodium intake in conscious mice
Q47962829Sciatic nerve transection evokes lasting up-regulation of angiotensin AT2 and AT1 receptor mRNA in adult rat dorsal root ganglia and sciatic nerves
Q43625220Selective down-regulation of AT2 receptors in uterine arteries from pregnant ewes given 24-h intravenous infusions of angiotensin II.
Q28594131Serotonin 2B receptor is required for heart development
Q51117577Sex- and age-related differences in the chronic pressure-natriuresis relationship: role of the angiotensin type 2 receptor.
Q33826656Signal transduction from the angiotensin II AT2 receptor
Q34697114Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training.
Q28645766Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control
Q33330952Specific single chain variable fragment (ScFv) antibodies to angiotensin II AT(2) receptor: evaluation of the angiotensin II receptor expression in normal and tumor-bearing mouse lung
Q33685969Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats.
Q36335687Structural basis for selectivity and diversity in angiotensin II receptors
Q37168385Suppression of Resting Metabolism by the Angiotensin AT2 Receptor
Q30304009Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor
Q42989490Sustained phospholipase D activation in response to angiotensin II but not carbachol in bovine adrenal glomerulosa cells
Q97543051TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2
Q33680652The AT2 receptor: fact, fancy and fantasy
Q36520049The Angiotensin II Type 2 Receptor in Brain Functions: An Update
Q37150747The Frail Renin-Angiotensin System
Q33962025The acute vascular effects of frusemide in heart failure
Q34086986The angiotensin II AT2 receptor is an AT1 receptor antagonist.
Q74428985The angiotensin II binding site on Mycoplasma hyorhynis is structurally distinct from mammalian AT1 and AT2 receptors
Q36058186The angiotensin II type 2 receptor activates flow-mediated outward remodelling through T cells-dependent interleukin-17 production
Q30413945The angiotensin II type 2 receptor and the kidney
Q37622583The angiotensin II type 2 receptor in the brain
Q40559527The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced obesity in rats
Q34019802The cardiac renin-angiotensin system: novel signaling mechanisms related to cardiac growth and function
Q59287172The influence of restraint on blood pressure in the rat
Q40853213The interaction of nitric oxide, bradykinin, and the angiotensin II type 2 receptor: lessons learned from transgenic mice
Q37526343The link between stress disorders and autonomic dysfunction in muscular dystrophy
Q37622572The past, present and future of angiotensin II type 2 receptor stimulation
Q37988002The regenerative potential of angiotensin AT2 receptor in cardiac repair.
Q35850561The renin-angiotensin system in kidney development
Q33217815The renin-angiotensin system: current data
Q35105871The role of ACE2 in cardiovascular physiology
Q41386967The role of angiotensin receptors in cardiovascular diseases
Q35028529The subtype 2 of angiotensin II receptors and pressure-natriuresis in adult rat kidneys
Q39376362The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases.
Q35677285Transgenesis and gene targeting in the mouse; tools for studying genetic determinants of hypertension
Q34028513Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways
Q33799227Transgenic and knockout models in renin-angiotensin system
Q52981348Transgenic animal models for the functional analysis of vasoactive peptides.
Q35850586Transgenic mice for studies of the renin-angiotensin system in hypertension.
Q34101139Transgenic mouse models of angiotensin receptor subtype function in the cardiovascular system
Q33887636Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
Q34144326Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland
Q38196317Unwrapping the origins and roles of the renal endothelium.
Q44650642Up-Regulation of Angiotensin II Type 2 Receptor in Rat Thoracic Aorta by Pressure-Overload
Q28077454Update on RAAS Modulation for the Treatment of Diabetic Cardiovascular Disease
Q46816577Valsartan abolishes most of the memory-improving effects of intracerebroventricular angiotensin II in rats.
Q37097104Vascular angiotensin AT2 receptors in hypertension and ageing
Q37112560Vascular biology of angiotensin and the impact of physical activity
Q34940868Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation.
Q34028504What can knockout mice contribute to an understanding of hypertension?

Q60079823Erratum: Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in micemain subjectP921

Search more.