The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity

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The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity is …
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P6179Dimensions Publication ID1000251163
P356DOI10.1038/NCB1474
P3181OpenCitations bibliographic resource ID5125574
P698PubMed publication ID16980960

P2093author name stringMiho Ohsugi
Tadashi Yamamoto
Naoki Oshimori
P2860cites workThe mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98pQ24311458
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomesQ24312101
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substratesQ24322852
Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complexQ24530072
The chromokinesin Kid is required for maintenance of proper metaphase spindle size.Q24535542
Formation of spindle poles by dynein/dynactin-dependent transport of NuMAQ24670127
Cdc2-mediated phosphorylation of Kid controls its distribution to spindle and chromosomesQ24675913
The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindlesQ24685481
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domainQ27642308
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose platesQ27860715
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinaseQ28212662
hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell divisionQ28217184
Polo-like kinases and the orchestration of cell divisionQ29616759
Centrosome composition and microtubule anchoring mechanismsQ29619588
Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosomeQ30442117
Regulating centrosomes by protein phosphorylation.Q34044967
Centrosome maturationQ34045013
Centrosome aberrations: cause or consequence of cancer progression?Q34157650
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.Q34195806
Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary ciliaQ34413778
Cell divisionQ35109702
Polar expeditions--provisioning the centrosome for mitosis.Q35140777
Centrosomal amplification and spindle multipolarity in cancer cellsQ35990959
Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entryQ37031680
Monoclonal antibodies to mitotic cellsQ37611790
Centrosomes split in the presence of impaired DNA integrity during mitosisQ39788663
Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesisQ40542776
Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defectsQ43207732
Roles of polo-like kinase 1 in the assembly of functional mitotic spindlesQ45086018
Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extractsQ46141991
Centrioles resist forces applied on centrosomes during G2/M transition.Q50768016
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectprotein kinase bindingQ14817984
Kizuna centrosomal proteinQ21114099
P304page(s)1095-101
P577publication date2006-10-01
P1433published inNature Cell BiologyQ1574111
P1476titleThe Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity
P478volume8