| scholarly article | Q13442814 |
| P50 | author | Jan Ellenberg | Q1296661 |
| P2093 | author name string | Izabela Sumara | |
| Toru Hirota | |||
| Jan-Michael Peters | |||
| Daniel Gerlich | |||
| Consuelo de la Torre | |||
| Juan F Giménez-Abián | |||
| Claudine Kraft | |||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1712-1722 | |
| P577 | publication date | 2004-10-01 | |
| P1433 | published in | Current Biology | Q1144851 |
| P1476 | title | Roles of polo-like kinase 1 in the assembly of functional mitotic spindles | |
| P478 | volume | 14 |
| Q24307672 | A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells |
| Q53097004 | A Kinase-Phosphatase Network that Regulates Kinetochore-Microtubule Attachments and the SAC. |
| Q91105748 | A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation |
| Q84007581 | A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion |
| Q28484219 | A series of beta-carboline derivatives inhibit the kinase activity of PLKs |
| Q92305752 | A solid-phase transfection platform for arrayed CRISPR screens |
| Q58718962 | A unified view of spatio-temporal control of mitotic entry: Polo kinase as the key |
| Q34771185 | Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer |
| Q39159112 | Abortive cell cycle events in the brains of scrapie-infected hamsters with remarkable decreases of PLK3/Cdc25C and increases of PLK1/cyclin B1. |
| Q37472274 | Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy |
| Q41880466 | All together now: Polo joins the kinase network controlling the spindle assembly checkpoint in Drosophila. |
| Q34430469 | Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation |
| Q42385854 | Balancing the kinetochore ledger |
| Q33999018 | Beyond taxanes: a review of novel agents that target mitotic tubulin and microtubules, kinases, and kinesins. |
| Q33836805 | CCT chaperonin complex is required for the biogenesis of functional Plk1. |
| Q38997789 | COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins |
| Q27305990 | Caenorhabditis elegans polo-like kinase PLK-1 is required for merging parental genomes into a single nucleus |
| Q36317230 | Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments |
| Q36149262 | Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope |
| Q90637868 | Cell cycle-independent furrowing triggered by phosphomimetic mutations of the INCENP STD motif requires Plk1 |
| Q54689852 | Centrobin regulates the assembly of functional mitotic spindles. |
| Q34055829 | Centrobin/NIP2 is a microtubule stabilizer whose activity is enhanced by PLK1 phosphorylation during mitosis |
| Q41199095 | Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro |
| Q30479187 | Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. |
| Q29871463 | Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation |
| Q92256956 | Classical and Emerging Regulatory Mechanisms of Cytokinesis in Animal Cells |
| Q36550391 | Cohesin and DNA damage repair |
| Q36054290 | Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma. |
| Q28288825 | Complex formation of Plk1 and INCENP required for metaphase-anaphase transition |
| Q35021877 | Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis. |
| Q26991874 | DNA damage associated with mitosis and cytokinesis failure |
| Q38103253 | Decoding ubiquitin for mitosis |
| Q33387164 | Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition |
| Q41916004 | Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting |
| Q36579320 | Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis. |
| Q30501259 | Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1 |
| Q30650928 | Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP. |
| Q24299033 | Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1 |
| Q30540597 | Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation |
| Q28286541 | Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit |
| Q36035584 | Enabling and disabling polo-like kinase 1 inhibition through chemical genetics |
| Q27306141 | Expression of constitutively active CDK1 stabilizes APC-Cdh1 substrates and potentiates premature spindle assembly and checkpoint function in G1 cells |
| Q36338599 | FANCA safeguards interphase and mitosis during hematopoiesis in vivo. |
| Q35592112 | From Plk1 to Plk5: functional evolution of polo-like kinases |
| Q42322255 | Furry protein promotes aurora A-mediated Polo-like kinase 1 activation. |
| Q39601527 | Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies |
| Q39390952 | Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target |
| Q47072115 | Heterologous expression of mammalian Plk1 in Drosophila reveals divergence from Polo during late mitosis. |
| Q38878829 | High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells |
| Q28477348 | High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888 |
| Q34652111 | High-throughput RNAi screening by time-lapse imaging of live human cells |
| Q37218015 | Human ABCB1 (P-glycoprotein) and ABCG2 mediate resistance to BI 2536, a potent and selective inhibitor of Polo-like kinase 1 |
| Q39127021 | Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods |
| Q35056261 | Illumination of mitotic orchestra during cell division: a Polo view |
| Q33817671 | Inferring cell cycle feedback regulation from gene expression data |
| Q28268658 | Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner |
| Q40222429 | Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance |
| Q40324279 | Inhibitory effect of Polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells |
| Q55512020 | Kinase and Phosphatase Cross-Talk at the Kinetochore. |
| Q40097772 | Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignment |
| Q36192035 | Kiss and break up--a safe passage to anaphase in mitosis and meiosis. |
| Q36189477 | Kizuna is a novel mitotic substrate for CDC25B phosphatase |
| Q53596078 | Kizuna takes pole position. |
| Q38989539 | Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells |
| Q35128226 | Loading of the 3F3/2 antigen onto kinetochores is dependent on the ordered assembly of the spindle checkpoint proteins |
| Q30441480 | Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells |
| Q55308042 | MAD1: Kinetochore Receptors and Catalytic Mechanisms. |
| Q27310288 | MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1 |
| Q34220987 | Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. |
| Q37728193 | Mechanisms of Chromosome Congression during Mitosis. |
| Q53615029 | Megakaryocyte polyploidization is associated with decreased expression of polo-like kinase (PLK). |
| Q38961886 | Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1. |
| Q40416068 | Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase |
| Q29620741 | Molecular architecture of the kinetochore-microtubule interface |
| Q27025174 | Molecular dynamics of PLK1 during mitosis |
| Q24310028 | Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment |
| Q27316964 | Multiple requirements of PLK1 during mouse oocyte maturation |
| Q46683202 | Multiple roles for separase auto-cleavage during the G2/M transition |
| Q24312184 | Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1 |
| Q90647026 | Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis |
| Q34519883 | Normal cells, but not cancer cells, survive severe Plk1 depletion |
| Q42166294 | P21-activated kinase is required for mitotic progression and regulates Plk1. |
| Q39012724 | PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy |
| Q57069974 | PLK1 as a potential prognostic marker of gastric cancer through MEK-ERK pathway on PDTX models |
| Q93116248 | PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling |
| Q35636562 | PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis |
| Q47971528 | PLK1 regulates spindle association of phosphorylated eukaryotic translation initiation factor 4E binding protein, and spindle function in mouse oocytes |
| Q40736757 | PLK1 regulates spindle formation kinetics and APC/C activation in mouse zygote |
| Q41569146 | PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2. |
| Q47368506 | PLK4: a link between centriole biogenesis and cancer |
| Q29615188 | Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes |
| Q30484139 | Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle. |
| Q24292817 | Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1 |
| Q43142770 | Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a |
| Q41459053 | Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis. |
| Q40464411 | Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling. |
| Q27334288 | Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines |
| Q41554827 | Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes |
| Q34149971 | Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission |
| Q30525261 | Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment. |
| Q39682585 | Plk1 regulates both ASAP localization and its role in spindle pole integrity |
| Q24318919 | Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora |
| Q36030471 | Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation. |
| Q28115063 | Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression |
| Q24338881 | Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components |
| Q51603331 | Plk1-mediated stabilization of 53BP1 through USP7 regulates centrosome positioning to maintain bipolarity. |
| Q30443415 | Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores |
| Q35235743 | Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo |
| Q37192073 | Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation |
| Q51991100 | Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1. |
| Q91906639 | Polo-like kinase 1 inhibition in NSCLC: mechanism of action and emerging predictive biomarkers |
| Q39380065 | Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice. |
| Q47397392 | Polo-like kinase 1 inhibition results in misaligned chromosomes and aberrant spindles in porcine oocytes during the first meiotic division |
| Q43601146 | Polo-like kinase 1 is essential for the first mitotic division in the mouse embryo |
| Q38984499 | Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis |
| Q27303017 | Polo-like kinase controls vertebrate spindle elongation and cytokinesis |
| Q36625772 | Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei |
| Q21090068 | Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1 |
| Q30528929 | Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing |
| Q91529267 | Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved |
| Q33259741 | Probing cell-division phenotype space and Polo-like kinase function using small molecules |
| Q26779135 | Putting a bit into the polo-box domain of polo-like kinase 1 |
| Q39451744 | Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome |
| Q38128358 | Real-time nanoscale proteomic analysis of the novel multi-kinase pathway inhibitor rigosertib to measure the response to treatment of cancer |
| Q42127116 | Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases |
| Q37015055 | Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1). |
| Q36919923 | Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by phosphorylation at a CDK site in mitosis |
| Q37811897 | Shared and separate functions of polo-like kinases and aurora kinases in cancer |
| Q46467809 | Sirt1 Regulates Microtubule Dynamics Through Negative Regulation of Plk1 in Mitosis. |
| Q28081253 | Spatiotemporal regulation of the anaphase-promoting complex in mitosis |
| Q37340912 | Spindle assembly defects leading to the formation of a monopolar mitotic apparatus |
| Q40479096 | Spindle checkpoint and apoptotic response in alpha-particle transformed human bronchial epithelial cells. |
| Q83225252 | Subcellular drug targeting illuminates local kinase action |
| Q36717905 | Targeted anti-mitotic therapies: can we improve on tubulin agents? |
| Q33564389 | Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells |
| Q38714999 | Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma |
| Q47139532 | Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck. |
| Q53348000 | Targeting polo-like kinase 1 for cancer therapy. |
| Q47263437 | Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis |
| Q35946386 | Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions |
| Q38707137 | The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation |
| Q24336860 | The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis |
| Q27320051 | The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation |
| Q37999289 | The Greatwall kinase: a new pathway in the control of the cell cycle |
| Q24545999 | The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation |
| Q24303592 | The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity |
| Q34541480 | The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr |
| Q29618398 | The anaphase promoting complex/cyclosome: a machine designed to destroy |
| Q37116059 | The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest |
| Q37031833 | The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores |
| Q34663848 | The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores |
| Q39130997 | The equilibrium of ubiquitination and deubiquitination at PLK1 regulates sister chromatid separation |
| Q33555628 | The natural product Aristolactam AIIIa as a new ligand targeting the polo-box domain of polo-like kinase 1 potently inhibits cancer cell proliferation |
| Q24297234 | The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus |
| Q38165149 | The role of polo-like kinase 1 in carcinogenesis: cause or consequence? |
| Q24322683 | Ubiquitylation-dependent localization of PLK1 in mitosis |
| Q38331761 | Understanding the Polo Kinase machine |
| Q33550033 | Use of cryopreserved cell aliquots in the high-throughput screening of small interfering RNA libraries |
| Q30480149 | Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis |
| Q33410018 | Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation |
| Q36497538 | WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression |
| Q34659879 | p38α MAPK Is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation |
| Q51528185 | p53 Suppresses E2F1-dependent PLK1 expression upon DNA damage by forming p53-E2F1-DNA complex. |
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