scholarly article | Q13442814 |
P50 | author | Peter Aplan | Q89272233 |
P2093 | author name string | Ahuvit David | |
Alwin Krämer | |||
Asher Castiel | |||
Shai Izraeli | |||
Ilan R Kirsch | |||
Michael Brandeis | |||
Sharon Moshkovitz | |||
Michal Mark Danieli | |||
P2860 | cites work | Chfr defines a mitotic stress checkpoint that delays entry into metaphase | Q22254761 |
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase | Q24301325 | ||
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion | Q24301594 | ||
PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein | Q24306346 | ||
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes | Q24312101 | ||
Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase | Q24321736 | ||
Chfr is linked to tumour metastasis through the downregulation of HDAC1 | Q24324032 | ||
Active cyclin B1-Cdk1 first appears on centrosomes in prophase | Q24338617 | ||
Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint | Q24530007 | ||
A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size | Q24570115 | ||
Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia | Q24594559 | ||
The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition | Q24652690 | ||
Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells | Q24676923 | ||
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice | Q24684680 | ||
Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR | Q28187458 | ||
Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity | Q28209840 | ||
Expression of the SIL gene is correlated with growth induction and cellular proliferation | Q28254853 | ||
Sil overexpression in lung cancer characterizes tumors with increased mitotic activity | Q28258388 | ||
The SIL gene is required for mouse embryonic axial development and left-right specification | Q28509071 | ||
Chfr is required for tumor suppression and Aurora A regulation | Q28510913 | ||
Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings | Q28769509 | ||
A molecular signature of metastasis in primary solid tumors | Q29614442 | ||
Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance | Q30477159 | ||
The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain | Q33323380 | ||
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. | Q33370199 | ||
Primary microcephaly: do all roads lead to Rome? | Q33629131 | ||
Drosophila Ana2 is a conserved centriole duplication factor | Q33643718 | ||
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4. | Q33960544 | ||
BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly | Q34085175 | ||
SAK/PLK4 is required for centriole duplication and flagella development | Q34472675 | ||
The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization | Q35950169 | ||
Polo-like kinase 1 is essential for early embryonic development and tumor suppression | Q36949896 | ||
Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly | Q37156137 | ||
Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1 | Q37267614 | ||
Nuclear localization of Chfr is crucial for its checkpoint function | Q39867562 | ||
The SIL gene is essential for mitotic entry and survival of cancer cells. | Q40141674 | ||
Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity | Q40144143 | ||
A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association. | Q40328385 | ||
The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centrosomal protein | Q40381206 | ||
Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis | Q40542776 | ||
The mitotic checkpoint gene, SIL is regulated by E2F1. | Q42126696 | ||
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles | Q45086018 | ||
The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus | Q45240522 | ||
Chfr interacts and colocalizes with TCTP to the mitotic spindle. | Q52587117 | ||
P433 | issue | Pt 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 532-539 | |
P577 | publication date | 2011-01-18 | |
P1433 | published in | Journal of Cell Science | Q1524177 |
P1476 | title | The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr | |
P478 | volume | 124 |
Q36961022 | 14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression |
Q26858999 | A developmental and genetic classification for malformations of cortical development: update 2012 |
Q36262514 | A novel function of the human oncogene Stil: Regulation of PC12 cell toxic susceptibility through the Shh pathway |
Q28551506 | Alcohol Regulates Genes that Are Associated with Response to Endocrine Therapy and Attenuates the Actions of Tamoxifen in Breast Cancer Cells |
Q36625721 | Building a centriole |
Q37967195 | CHFR: a key checkpoint component implicated in a wide range of cancers |
Q36848137 | Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly |
Q36202759 | Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast |
Q37158051 | Genetic causes of microcephaly and lessons for neuronal development |
Q41915395 | Identifying protein-protein interaction sites using peptide arrays |
Q41928965 | Lack of centrioles and primary cilia in STIL(-/-) mouse embryos |
Q30559126 | Loss of centrioles causes chromosomal instability in vertebrate somatic cells |
Q56770849 | Malformations of cortical development and epilepsy |
Q30556376 | Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression. |
Q40148678 | Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells |
Q49918080 | Novel STIL Compound Heterozygous Mutations Cause Severe Fetal Microcephaly and Centriolar Lengthening |
Q36564548 | Primary cilia and aberrant cell signaling in epithelial ovarian cancer |
Q27674490 | SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism inC. eleganscentriole assembly |
Q47851151 | STIL balancing primary microcephaly and cancer |
Q64087935 | STIL: a multi-function protein required for dopaminergic neural proliferation, protection, and regeneration |
Q33689051 | Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer |
Q28071761 | The PLK4-STIL-SAS-6 module at the core of centriole duplication |
Q53090758 | The STIL protein contains intrinsically disordered regions that mediate its protein-protein interactions. |
Q38222110 | The centrosome duplication cycle in health and disease. |
Q24294326 | The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation |
Q37622621 | Transcription of the SCL/TAL1 interrupting Locus (Stil) is required for cell proliferation in adult Zebrafish Retinas |
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