Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.

scientific article

Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PGEN.1002566
P932PMC publication ID3315461
P698PubMed publication ID22479190
P5875ResearchGate publication ID223987299

P50authorPaul A TrainorQ48687276
P2093author name stringJill Dixon
Michael J Dixon
Daisuke Sakai
P2860cites workControl of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium.Q50661583
Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouseQ51299150
Dynamic expression of murine Cux2 in craniofacial, limb, urogenital and neuronal primordia.Q52100384
Structure, function and assembly of the nucleolusQ52223868
A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cellsQ52546192
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wallQ64117434
Recurrence of Treacher Collins' syndrome with sonographic findingsQ72084499
Isolation and culture of whole postimplantation embryos and germ layer derivativesQ72583899
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1Q79754843
Cellular allometry: the spindle in development and inheritanceQ84595461
Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for preventionQ84794775
Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.Q37162736
Neurogenesis and asymmetric cell divisionQ37177866
DNA repair deficiency and neurological diseaseQ37368873
Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortexQ38799056
Prenatal sonographic diagnosis of Treacher Collins syndrome: a case and review of the literatureQ40957219
The predictive value of microcephaly during the first year of life for mental retardation at seven yearsQ41930655
Structural basis for self-renewal of neural progenitors in cortical neurogenesis.Q42130839
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.Q42522587
Sequence analysis, identification of evolutionary conserved motifs and expression analysis of murine tcof1 provide further evidence for a potential function for the gene and its human homologue, TCOF1.Q42656543
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.Q43072719
Roles of polo-like kinase 1 in the assembly of functional mitotic spindlesQ45086018
Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest developmentQ46970821
Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cellsQ47401361
Genetic background has a major effect on the penetrance and severity of craniofacial defects in mice heterozygous for the gene encoding the nucleolar protein TreacleQ47886958
The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factorQ24299223
Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1Q24299765
Characterization of Su48, a centrosome protein essential for cell divisionQ24546644
The spindle-assembly checkpoint in space and timeQ27860766
Neurons derived from radial glial cells establish radial units in neocortexQ28202112
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phasesQ28236938
Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual dispositionQ28237754
Evolution of the neocortex: a perspective from developmental biologyQ28258984
Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative GroupQ28273395
The cell biology of neurogenesisQ28284165
Cytoskeletal genes regulating brain sizeQ28285696
Asymmetric centrosome inheritance maintains neural progenitors in the neocortexQ28505215
Pax-6 is involved in the specification of hindbrain motor neuron subtypeQ28567078
Mitotic spindle regulation by Nde1 controls cerebral cortical sizeQ28592549
Polo-like kinases and the orchestration of cell divisionQ29616759
Primary microcephaly: do all roads lead to Rome?Q33629131
Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesisQ34304333
Genotyping in 46 patients with tentative diagnosis of Treacher Collins syndrome revealed unexpected phenotypic variationQ34344840
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.Q34575151
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.Q34618385
Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.Q34978484
Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesisQ34978629
Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalitiesQ35011856
Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.Q35781685
Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanismQ36658115
The centrosome in neuronal developmentQ36786169
Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesisQ37082090
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectneurogenesisQ1456827
P304page(s)e1002566
P577publication date2012-03-29
P1433published inPLOS GeneticsQ1893441
P1476titleMammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells
P478volume8