scholarly article | Q13442814 |
P50 | author | Christopher A. Walsh | Q23135514 |
P2093 | author name string | Yuanyi Feng | |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | NudE neurodevelopment protein 1 | Q21982880 |
P304 | page(s) | 279–293 | |
P577 | publication date | 2004-10-14 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | Mitotic spindle regulation by Nde1 controls cerebral cortical size | |
P478 | volume | 44 |
Q50310657 | 16p13.11 duplication is a risk factor for a wide spectrum of neuropsychiatric disorders |
Q35644304 | A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons |
Q37660908 | A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling |
Q26858999 | A developmental and genetic classification for malformations of cortical development: update 2012 |
Q79777437 | A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome |
Q38750052 | ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. |
Q41103145 | ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination |
Q28272263 | Absence of Fyn and Src causes a reeler-like phenotype |
Q30487112 | Advanced microscopic imaging methods to investigate cortical development and the etiology of mental retardation |
Q24620889 | Allelic diversity in human developmental neurogenetics: insights into biology and disease |
Q38004611 | An oblique view on the role of spindle orientation in vertebrate neurogenesis. |
Q50313705 | Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation |
Q24550947 | Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells |
Q91957851 | Bi-allelic Variants in DYNC1I2 Cause Syndromic Microcephaly with Intellectual Disability, Cerebral Malformations, and Dysmorphic Facial Features |
Q64229757 | Brain Organoids-A Bottom-Up Approach for Studying Human Neurodevelopment |
Q96128071 | Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease |
Q36724451 | CCDC88A mutations cause PEHO-like syndrome in humans and mouse |
Q30477056 | CLIP-170 homologue and NUDE play overlapping roles in NUDF localization in Aspergillus nidulans |
Q63977020 | Cdk1 phosphorylation of the dynein adapter Nde1 controls cargo binding from G2 to anaphase |
Q36021561 | Cdk5rap2 exposes the centrosomal root of microcephaly syndromes |
Q28594217 | Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors |
Q38578735 | Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development. |
Q41869289 | Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers |
Q36148380 | Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length |
Q24315867 | Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes |
Q30630071 | Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1 |
Q24336419 | Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylation |
Q41932064 | Centrosome amplification causes microcephaly |
Q24653494 | Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. |
Q34218804 | Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly. |
Q35559947 | Cilia and cell cycle re-entry: more than a coincidence |
Q28067455 | Cilium assembly and disassembly |
Q38839935 | Clinical utility gene card for: 16p13.11 microdeletion syndrome |
Q33654193 | Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes |
Q34161165 | Coevolution of generalist feeding ecologies and gyrencephalic mushroom bodies in insects |
Q28591177 | Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality |
Q38004610 | Control of asymmetric cell division of mammalian neural progenitors. |
Q38194922 | Control of cerebral size and thickness |
Q30485002 | Cytokinesis of neuroepithelial cells can divide their basal process before anaphase |
Q28508499 | Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway |
Q33911093 | Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans |
Q36672834 | Cytoskeleton in action: lissencephaly, a neuronal migration disorder |
Q47380363 | DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. |
Q36634401 | DISC1 genetics, biology and psychiatric illness |
Q28302106 | DISC1-binding proteins in neural development, signalling and schizophrenia |
Q26851318 | DISC1: a key lead in studying cortical development and associated brain disorders |
Q38648132 | Decoding the molecular mechanisms of neuronal migration using in utero electroporation |
Q35579834 | Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons |
Q41495770 | Deletion of RIC8A in neural precursor cells leads to altered neurogenesis and neonatal lethality of mouse |
Q35668966 | Dendrite arborization requires the dynein cofactor NudE |
Q30493243 | Distinct dose-dependent cortical neuronal migration and neurite extension defects in Lis1 and Ndel1 mutant mice |
Q83771992 | Do cilia put brakes on the cell cycle? |
Q38308258 | Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue |
Q39802765 | EFHC1 interacts with microtubules to regulate cell division and cortical development |
Q92403202 | Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma |
Q36794017 | Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding |
Q38781426 | Emerging roles for motor proteins in progenitor cell behavior and neuronal migration during brain development |
Q92568256 | Emerging roles of the centrosome in neuronal development |
Q92218376 | Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development |
Q35293785 | Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development |
Q28729961 | Evolutionary genomics of human intellectual disability |
Q26864155 | Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders |
Q38915638 | Face off against ROS: Tcof1/Treacle safeguards neuroepithelial cells and progenitor neural crest cells from oxidative stress during craniofacial development. |
Q35379284 | Familial imbalance in 16p13.11 leads to a dosage compensation rearrangement in an unaffected carrier |
Q34593858 | Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1. |
Q28591363 | Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis |
Q24635628 | Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia |
Q28590062 | GPR56 regulates pial basement membrane integrity and cortical lamination |
Q35579780 | Gene networks underlying convergent and pleiotropic phenotypes in a large and systematically-phenotyped cohort with heterogeneous developmental disorders. |
Q30815096 | Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness |
Q39285656 | Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex |
Q37158051 | Genetic causes of microcephaly and lessons for neuronal development |
Q34604171 | Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration |
Q34478370 | Genomic variants and variations in malformations of cortical development |
Q102388697 | Gestational diabetes induces behavioral and brain gene transcription dysregulation in adult offspring |
Q28655454 | Growth and folding of the mammalian cerebral cortex: from molecules to malformations |
Q33265521 | Heterogeneity of mammary lesions represent molecular differences |
Q41858741 | Human NDE1 splicing and mammalian brain development. |
Q41918485 | Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2. |
Q34181137 | Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected] |
Q24294765 | Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis |
Q35369750 | Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility. |
Q34452659 | Identification of a Novel Dynein Binding Domain in Nudel Essential for Spindle Pole Organization in Xenopus Egg Extract |
Q33435631 | Identification of genes differentially expressed in dorsal and ventral chick midbrain during early development |
Q24656124 | Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system |
Q42486775 | Interkinetic nuclear migration in the mouse embryonic ureteric epithelium: Possible implication for congenital anomalies of the kidney and urinary tract |
Q41934993 | Interkinetic nuclear movement in the ventricular zone of the cortex. |
Q36127211 | Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin. |
Q57280070 | Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex |
Q35797268 | Katanin p80 regulates human cortical development by limiting centriole and cilia number |
Q36255663 | LIS-less neurons don't even make it to the starting gate |
Q28574389 | LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages |
Q30560241 | LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. |
Q30608477 | Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia |
Q28584948 | Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination |
Q36617722 | Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more |
Q37778122 | Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies |
Q34293449 | Live imaging of mitosis in the developing mouse embryonic cortex |
Q27334950 | Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro |
Q37295265 | MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex |
Q34700227 | Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders. |
Q56232683 | Malformations of cortical development |
Q31162335 | Malformations of cortical development: genetic mechanisms and diagnostic approach |
Q34220987 | Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. |
Q30676872 | Mechanism and regulation of cytoplasmic dynein |
Q41921410 | Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate |
Q41930126 | Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size |
Q24317320 | Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex |
Q42428366 | Microtubule-associated defects caused by EFHC1 mutations in juvenile myoclonic epilepsy |
Q34965715 | Microtubule-associated type II protein kinase A is important for neurite elongation. |
Q24314268 | Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly |
Q36486600 | Mitotic spindle (DIS)orientation and DISease: cause or consequence? |
Q37323987 | Modes and mishaps of neuronal migration in the mammalian brain |
Q35626052 | Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. |
Q21146375 | Molecular insights into human brain evolution |
Q35077279 | Morphological and functional aspects of progenitors perturbed in cortical malformations |
Q28593991 | Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport |
Q24298230 | Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human |
Q24301645 | Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture |
Q42381514 | N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex |
Q38981297 | NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness |
Q39919009 | NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction |
Q37208704 | NDE1 and NDEL1: twin neurodevelopmental proteins with similar 'nature' but different 'nurture'. |
Q55185737 | NDE1 positively regulates oligodendrocyte morphological differentiation. |
Q30567482 | Native disorder mediates binding of dynein to NudE and dynactin |
Q34796294 | Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry |
Q24318793 | Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity. |
Q37939016 | Ndel1, Nudel (Noodle): flexible in the cell? |
Q30528662 | Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon |
Q36580299 | Neural development is dependent on the function of specificity protein 2 in cell cycle progression |
Q36671367 | Neural stem cells and their manipulation |
Q42522587 | Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. |
Q43072719 | Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. |
Q47720809 | Neurogenesis in G minor |
Q30431661 | Neuronal migration defects in the Loa dynein mutant mouse |
Q36880780 | Neuronal migration: unraveling the molecular pathway with humans, mice, and a fungus |
Q34241703 | Neuropathology of 16p13.11 deletion in epilepsy |
Q28081713 | New frontiers: discovering cilia-independent functions of cilia proteins |
Q41934017 | Novel NDE1 homozygous mutation resulting in microhydranencephaly and not microlyssencephaly |
Q30494259 | Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction |
Q36520499 | Novel genetic tools facilitate the study of cortical neuron migration |
Q38274815 | NudC is required for interkinetic nuclear migration and neuronal migration during neocortical development. |
Q36118856 | NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochores |
Q27937675 | NudEL targets dynein to microtubule ends through LIS1. |
Q24540219 | Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly |
Q30479787 | Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase |
Q34266814 | OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease |
Q52884385 | Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports. |
Q39366533 | PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1 |
Q34705135 | Phenotypic manifestations of copy number variation in chromosome 16p13.11. |
Q37426383 | Polarity regulation in migrating neurons in the cortex |
Q47228439 | Primary cilia proteins: ciliary and extraciliary sites and functions. |
Q38241685 | Progenitor genealogy in the developing cerebral cortex |
Q36025228 | Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint |
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Q35572513 | Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly |
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