Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex

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Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2013.12.016
P3181OpenCitations bibliographic resource ID4752813
P698PubMed publication ID24388750
P5875ResearchGate publication ID259586718

P50authorFeng ZhangQ47695797
Zhiheng XuQ60451495
P2093author name stringDan Xu
Yiming Sun
Yaqing Wang
P2860cites workMany roads lead to primary autosomal recessive microcephalyQ35014103
Cell migration in the forebrainQ35081536
What disorders of cortical development tell us about the cortex: one plus one does not always make twoQ35115582
Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophreniaQ35569556
A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal functionQ36036561
Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous systemQ36294221
WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progressionQ36497538
The JNK pathway and neuronal migrationQ37013713
Mechanisms of asymmetric stem cell divisionQ37092865
Shaping our minds: stem and progenitor cell diversity in the mammalian neocortexQ38073393
Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.Q38314666
Orienting fate: spatial regulation of neurogenic divisionsQ39247291
Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.Q39614258
A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.Q39775444
Docking interactions of the JNK scaffold protein WDR62.Q42533944
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain developmentQ48219557
POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migrationQ48384815
A common mechanism for microcephalyQ82083066
Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformationsQ24296941
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architectureQ24301645
WDR62 is associated with the spindle pole and is mutated in human microcephalyQ24301673
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cellsQ24550947
Autosomal Recessive Primary Microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuumQ24570114
Neurons derived from radial glial cells establish radial units in neocortexQ28202112
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phasesQ28236938
Asymmetric centrosome inheritance maintains neural progenitors in the neocortexQ28505215
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathwayQ28506694
ASPM regulates Wnt signaling pathway activity in the developing brainQ28508236
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.Q28567147
LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stagesQ28574389
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rateQ28589409
Mitotic spindle regulation by Nde1 controls cerebral cortical sizeQ28592549
Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitorsQ28594217
Identification of genes periodically expressed in the human cell cycle and their expression in tumorsQ29619131
Primary microcephaly: do all roads lead to Rome?Q33629131
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.Q33960544
The suppression of CRMP2 expression by bone morphogenetic protein (BMP)-SMAD gradient signaling controls multiple stages of neuronal developmentQ34385933
Cell-cycle control and cortical developmentQ34630030
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmicrocephalyQ431643
neurogenesisQ1456827
mitotic spindle organizationQ14878173
WD repeat domain 62Q21105817
P304page(s)104-16
P577publication date2014-01-16
P1433published inCell ReportsQ5058165
P1476titleMicrocephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex
P478volume6