Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response is …
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scholarly articleQ13442814

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P356DOI10.1016/J.CELL.2005.11.040
P8608Fatcat IDrelease_zpy7aiqjzzc3vp43rqoogyejly
P3181OpenCitations bibliographic resource ID756240
P698PubMed publication ID16469704
P5875ResearchGate publication ID51372548

P50authorThomas L SaundersQ40082893
Kezhong ZhangQ64604817
Thomas RutkowskiQ73255638
P2093author name stringJun Wu
Sung Hoon Back
Randal J Kaufman
Xiaohua Shen
Kenjiro Sakaki
P2860cites workMolecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cellsQ22007975
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factorsQ22008465
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expressionQ24291231
Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysisQ24537679
The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinomaQ24805822
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.Q24815740
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPsQ28115918
Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to GolgiQ28141775
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humansQ28145545
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factorQ28238069
Acute-phase proteins and other systemic responses to inflammationQ28296941
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevationQ28365331
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytesQ28580776
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studiesQ28611460
Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegmentQ28640526
Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segmentQ28644805
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signalsQ28646129
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controlsQ29547730
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interferenceQ29615920
Decoding the patterns of self and nonself by the innate immune systemQ29618448
CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signalsQ29620470
Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational changeQ33927526
Infection and inflammation-induced proatherogenic changes of lipoproteinsQ33935040
Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteinsQ34104923
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart diseaseQ34311841
Innate and acquired immunity intersect in a global view of the acute-phase responseQ34329553
Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulumQ34358672
Orchestrating the unfolded protein response in health and diseaseQ35001604
Bioengineering of coagulation factor VIII for improved secretionQ38345967
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.Q42456186
Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1.Q42819162
C-reactive protein levels and outcomes after statin therapyQ45213511
Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery diseaseQ45213515
Comparison of the associations of apolipoprotein B and non-high-density lipoprotein cholesterol with other cardiovascular risk factors in patients with the metabolic syndrome in the Insulin Resistance Atherosclerosis StudyQ46207351
Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteinsQ47851307
Transport-Dependent Proteolysis of SREBPQ54231898
A time-dependent phase shift in the mammalian unfolded protein responseQ72997174
Role of STAT3 and C/EBP in cytokine-dependent expression of the mouse serum amyloid P-component (SAP) and C-reactive protein (CRP) genesQ73953977
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
inflammationQ101991
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stressQ21109197
activating transcription factor 6Q21116808
CAMP responsive element binding protein 3 like 3Q21116826
CAMP responsive element binding protein 3-like 3Q21494286
P304page(s)587-599
P577publication date2006-02-01
P1433published inCellQ655814
P1476titleEndoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
P478volume124