scholarly article | Q13442814 |
P356 | DOI | 10.1128/MCB.22.16.5639-5649.2002 |
P8608 | Fatcat ID | release_wubv42oif5e6dgo77dkkhrds2u |
P932 | PMC publication ID | 133973 |
P698 | PubMed publication ID | 12138176 |
P50 | author | Vikram Misra | Q57765186 |
Peter O'Hare | Q61306670 | ||
P2093 | author name string | Noreen Rapin | |
Erin Smith-Windsor | |||
Camilo Raggo | |||
Julie Stirling | |||
Philipe Gobeil | |||
P2860 | cites work | Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells | Q22007975 |
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 | ||
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latency | Q22011024 | ||
Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation | Q22253188 | ||
ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1 | Q22254333 | ||
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis | Q24310555 | ||
Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein | Q24320818 | ||
Interaction of ATF6 and serum response factor | Q24336048 | ||
Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor | Q24336173 | ||
The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF | Q24523280 | ||
Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP | Q24603763 | ||
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood | Q24614744 | ||
N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the host cell factor-1 binding motif | Q24649820 | ||
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs | Q28115918 | ||
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE | Q28139998 | ||
Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi | Q28141775 | ||
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans | Q28145545 | ||
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease | Q28344251 | ||
Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency | Q28504545 | ||
LZIP-1 and LZIP-2: two novel members of the bZIP family | Q28585015 | ||
Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies | Q28611460 | ||
Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins | Q28640407 | ||
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins | Q29620170 | ||
Presenilins, processing of beta-amyloid precursor protein, and notch signaling. | Q33684040 | ||
Presenilins: molecular switches between proteolysis and signal transduction | Q33730415 | ||
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes | Q33916842 | ||
Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. | Q34424993 | ||
Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi | Q35644888 | ||
Mammalian stress response: induction of the glucose-regulated protein family | Q36183765 | ||
A cyclic AMP-responsive element-binding transcriptional activator in Drosophila melanogaster, dCREB-A, is a member of the leucine zipper family | Q36701321 | ||
The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex | Q39727479 | ||
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1. | Q40109691 | ||
The cellular response to unfolded proteins: intercompartmental signaling | Q40535495 | ||
Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning | Q41028518 | ||
Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection | Q41260355 | ||
Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. | Q44697855 | ||
A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. | Q44998479 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
Cyclic AMP prevents an increase in GAP-43 but promotes neurite growth in cultured adult rat dorsal root ganglion neurons. | Q52164368 | ||
Transport-Dependent Proteolysis of SREBP | Q54231898 | ||
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis | Q77798021 | ||
P433 | issue | 16 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
proteolysis | Q33123 | ||
P304 | page(s) | 5639-5649 | |
P577 | publication date | 2002-08-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis | |
P478 | volume | 22 |
Q37663300 | A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens |
Q91875055 | A mutation in Site-1 Protease is associated with a complex phenotype that includes episodic hyperCKemia and focal myoedema |
Q24318529 | A novel isoform of human LZIP negatively regulates the transactivation of the glucocorticoid receptor |
Q24317491 | A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response |
Q33262919 | Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins |
Q28082366 | Advances and New Concepts in Alcohol-Induced Organelle Stress, Unfolded Protein Responses and Organ Damage |
Q36673609 | An orchestrated program regulating secretory pathway genes and cargos by the transmembrane transcription factor CREB-H. |
Q36898912 | Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons |
Q92317240 | Axotomy Induces Phasic Alterations in Luman/CREB3 Expression and Nuclear Localization in Injured and Contralateral Uninjured Sensory Neurons: Correlation With Intrinsic Axon Growth Capacity |
Q24337349 | BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer |
Q42760035 | CREB3 subfamily transcription factors are not created equal: Recent insights from global analyses and animal models. |
Q50296854 | CREB3 translocates from the cytosol to the nucleus |
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Q38316703 | Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress |
Q42664049 | Cloning and characterization of rat Luman/CREB3, a transcription factor highly expressed in nervous system tissue. |
Q36315764 | Crimean-Congo hemorrhagic fever virus glycoprotein processing by the endoprotease SKI-1/S1P is critical for virus infectivity |
Q38067504 | Current drug discovery strategies against arenavirus infections. |
Q24320231 | DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation |
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Q38178193 | DC-STAMP, the key fusion-mediating molecule in osteoclastogenesis. |
Q38344667 | Development of protein-based inhibitors of the proprotein of convertase SKI-1/S1P: processing of SREBP-2, ATF6, and a viral glycoprotein |
Q37797970 | Diabetes as a disease of endoplasmic reticulum stress |
Q80238624 | Differential subcellular localization and activity of kelch repeat proteins KLHDC1 and KLHDC2 |
Q81604029 | ER stress signaling by regulated proteolysis of ATF6 |
Q34708452 | Endoplasmic reticulum association and N-linked glycosylation of the human Nrf3 transcription factor |
Q24304232 | Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response |
Q26864238 | Endoplasmic reticulum stress and type 2 diabetes |
Q36844431 | Endoplasmic reticulum stress: signaling the unfolded protein response |
Q37602123 | Expression pattern implicates a potential role for luman recruitment factor in the process of implantation in uteri and development of preimplantation embryos in mice |
Q42237860 | GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion |
Q24815740 | Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. |
Q41646513 | HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress. |
Q42184608 | Herpes simplex virus-1 disarms the unfolded protein response in the early stages of infection. |
Q35605069 | Human leucine zipper protein sLZIP induces migration and invasion of cervical cancer cells via expression of matrix metalloproteinase-9. |
Q35914983 | Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice |
Q45327325 | Interplay between hepatitis C virus and ARF4. |
Q38316360 | JAB1/CSN5 inhibits the activity of Luman/CREB3 by promoting its degradation |
Q36223723 | Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation. |
Q42322098 | Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element |
Q24300509 | Luman is capable of binding and activating transcription from the unfolded protein response element |
Q41971020 | Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization |
Q24301000 | Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element |
Q50296852 | MBTPS1 (S1P) cleaves CREB3 |
Q50296853 | MBTPS2 (S2P) cleaves CREB3 |
Q39314148 | Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF. |
Q40034529 | Novel Brn3a cis-acting sequences mediate transcription of human trkA in neurons. |
Q38346133 | Organelle autoregulation-stress responses in the ER, Golgi, mitochondria and lysosome |
Q33543763 | PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes |
Q80098102 | Primate cytomegalovirus US12 gene family: a distinct and diverse clade of seven-transmembrane proteins |
Q37847814 | Regulated intramembrane proteolysis: signaling pathways and biological functions |
Q24293528 | Regulation of ADP-ribosylation factor 4 expression by small leucine zipper protein and involvement in breast cancer cell migration |
Q37352508 | Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences. |
Q42952040 | Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress |
Q38149888 | Roles of regulated intramembrane proteolysis in virus infection and antiviral immunity |
Q34526352 | Sensing nerve injury at the axonal ER: activated Luman/CREB3 serves as a novel axonally synthesized retrograde regeneration signal |
Q37622607 | Signalling pathways in the unfolded protein response: development from yeast to mammals |
Q50603977 | Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. |
Q34547044 | Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors |
Q58640364 | The Unfolded Protein Response and Cholesterol Biosynthesis Link Luman/CREB3 to Regenerative Axon Growth in Sensory Neurons |
Q37006310 | The endoplasmic reticulum and the unfolded protein response |
Q38201042 | The essential biology of the endoplasmic reticulum stress response for structural and computational biologists. |
Q24805822 | The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma |
Q38253020 | The neuroimmunology of degeneration and regeneration in the peripheral nervous system. |
Q34466767 | The neuronal host cell factor-binding protein Zhangfei inhibits herpes simplex virus replication |
Q40264454 | The proprotein convertase SKI-1/S1P. In vitro analysis of Lassa virus glycoprotein-derived substrates and ex vivo validation of irreversible peptide inhibitors |
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Q28258161 | The proprotein convertases and their implication in sterol and/or lipid metabolism |
Q38093057 | The role of the unfolded protein response in diabetes mellitus |
Q37860033 | The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology |
Q26851197 | The site-2 protease |
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Q50336411 | Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis |
Q34026175 | Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy |
Q40090967 | Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells |
Q24294669 | Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman |
Q34882839 | Zhangfei, a novel regulator of the human nerve growth factor receptor, trkA. |
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