A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis

scientific article

A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M407165200
P8608Fatcat IDrelease_hlrdzaqbsjc2lh42kpw7jtr6ta
P698PubMed publication ID15371445

P50authorXin PanQ79188148
P2093author name stringJie Wang
Ai-Ling Li
Bao-Feng Jin
Bei-Fen Shen
Hui-Yan Li
Jiang-Hong Man
Kun He
Ming Yu
Tao Zhou
Xue-Min Zhang
Xiao-Dan Yu
Qi-Nong Ye
Mei-Ru Hu
Song-Cheng Yang
P2860cites workGeneration of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental studyQ35268497
Control of apoptosis by p53.Q35603381
Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix-induced apoptosisQ36294095
Proteomic analysis of eIF-5A in lung adenocarcinomas.Q38355758
Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neuronsQ39922763
Is hypusine essential for eukaryotic cell proliferation?Q40715008
p53 Activation by nitric oxide involves down-regulation of Mdm2.Q40747960
Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.Q40845331
Hypusine is essential for eukaryotic cell proliferation.Q41585515
Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cellsQ42800718
Inhibition of CD83 cell surface expression during dendritic cell maturation by interference with nuclear export of CD83 mRNA.Q42972688
p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B-dependent transcription and stabilization by serine 15 phosphorylationQ44045943
Immunohistochemical detection of c-erbB-2 and p53 in benign breast disease and breast cancer riskQ44397218
Increasing complexity of the Ras signaling pathwayQ47762067
Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding siteQ49110267
p53 De-ubiquitination: at the edge between life and deathQ74221492
Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting proteinQ24291545
Induced gene expression of the hypusine-containing protein eukaryotic initiation factor 5A in activated human T lymphocytesQ24562720
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
Surfing the p53 networkQ28032484
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteinsQ28139757
The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifsQ28206704
Translational control in mammalian cellsQ28295830
PICK1 interacts with and regulates PKC phosphorylation of mGLUR7Q28576999
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5AQ28586364
Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopesQ31011088
Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.Q34283106
Biochemistry and function of hypusine formation on eukaryotic initiation factor 5A.Q34437938
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
protein N-terminus bindingQ14817992
Eukaryotic translation initiation factor 5AQ21112050
Syndecan binding proteinQ21131034
P1104number of pages8
P304page(s)49251-49258
P577publication date2004-09-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleA novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis
P478volume279

Reverse relations

cites work (P2860)
Q61800679A PDZ Protein MDA-9/Syntenin: As a Target for Cancer Therapy
Q57228502Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A)
Q46542243Antisense suppression of deoxyhypusine synthase in tomato delays fruit softening and alters growth and development
Q49385083Ascending the PEAK1 toward targeting TGFβ during cancer progression: Recent advances and future perspectives
Q31077285Characterization of a eukaryotic translation initiation factor 5A homolog from Tamarix androssowii involved in plant abiotic stress tolerance
Q24814274Delayed polarization of mononuclear phagocyte transcriptional program by type I interferon isoforms
Q39980089Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes
Q34499945Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.
Q27930978Dimerization of the yeast eukaryotic translation initiation factor 5A requires hypusine and is RNA dependent.
Q39144255Down-regulation of eIF5A-2 prevents epithelial-mesenchymal transition in non-small-cell lung cancer cells
Q38298226Effectiveness of gene expression profiling for response prediction of rectal cancer to preoperative radiotherapy
Q35693689Elongation factor P mediates a novel post-transcriptional regulatory pathway critical for bacterial virulence
Q92641240Epigenetic Regulation of Metabolism and Inflammation by Calorie Restriction
Q34422512Eukaryotic initiation factor 5A plays an essential role in luteinizing hormone receptor regulation
Q24338148Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling
Q44163402Eukaryotic translation initiation factor 5A is involved in pathogen-induced cell death and development of disease symptoms in Arabidopsis
Q30436677Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury
Q39380134Evaluation of deoxyhypusine synthase inhibitors targeting BCR-ABL positive leukemias
Q34395707Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies
Q33886406Expression of measles virus nucleoprotein induces apoptosis and modulates diverse functional proteins in cultured mammalian cells
Q51752762Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death.
Q24337919Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen
Q41899066Host and virus protein interaction studies in understanding shrimp virus gene function
Q33629378Identification and characterization of genes associated with tapping panel dryness from Hevea brasiliensis latex using suppression subtractive hybridization
Q33573655Influence of heart failure on nucleocytoplasmic transport in human cardiomyocytes
Q34096434Inhibition of glycogen phosphorylation induces changes in cellular proteome and signaling pathways in MIA pancreatic cancer cells
Q28385549Mechanistic Study on the Reduction of SWCNT-induced Cytotoxicity by Albumin Coating
Q33563502MicroRNA-434-3p regulates age-related apoptosis through eIF5A1 in the skeletal muscle
Q36085366Modulation of eIF5A expression using SNS01 nanoparticles inhibits NF-κB activity and tumor growth in murine models of multiple myeloma
Q37236208Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression Profiling
Q35676858Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor
Q48154027Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism.
Q34137202Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients.
Q33547691ProbFAST: Probabilistic functional analysis system tool
Q50442509Protein profiles in zebrafish (Danio rerio) brains exposed to chronic microcystin-LR
Q59800430Proteomic Analysis of Biomphalaria glabrata Hemocytes During in vitro Encapsulation of Schistosoma mansoni Sporocysts
Q33555329Proteomic alterations in progeny of irradiated human liver cells
Q37092614Proteomic analysis of protein expression profiles during hyperthermia-induced apoptosis in Tca8113 cells
Q39218842Proteomic analysis of rosiglitazone and guggulsterone treated 3T3-L1 preadipocytes
Q61815131Quantitative Proteomic Analysis of Castor ( L.) Seeds During Early Imbibition Provided Novel Insights into Cold Stress Response
Q38316877Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression.
Q46977439Role of hypusinated eukaryotic translation initiation factor 5A in polyamine depletion-induced cytostasis
Q36863596Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells
Q38163977Roles of eukaryotic initiation factor 5A2 in human cancer.
Q35618595SNS01-T modulation of eIF5A inhibits B-cell cancer progression and synergizes with bortezomib and lenalidomide
Q39179665Selenium mediated arsenic toxicity modifies cytotoxicity, reactive oxygen species and phosphorylated proteins
Q37731379Shrimp molecular responses to viral pathogens
Q34638020Syndecan binding protein (SDCBP) is overexpressed in estrogen receptor negative breast cancers, and is a potential promoter for tumor proliferation
Q36248114Targeting tumor invasion: the roles of MDA-9/Syntenin
Q50713258The Arabidopsis eukaryotic translation initiation factor eIF5A-2 regulates root protoxylem development by modulating cytokinin signaling.
Q37740676The Translation Initiation Factor 1A (TheIF1A) from Tamarix hispida Is Regulated by a Dof Transcription Factor and Increased Abiotic Stress Tolerance
Q37332795The effect of hypusine modification on the intracellular localization of eIF5A.
Q33389509The role of polyamines in protein-dependent hypoxic tolerance of Drosophila
Q30435990The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice
Q33291071Transcriptional oncogenomic hot spots in Barrett's adenocarcinomas: serial analysis of gene expression
Q42017705Transgenic mice overexpressing glia maturation factor-β, an oxidative stress inducible gene, show premature aging due to Zmpste24 down-regulation
Q24319664Ubc9 interacts with SOX4 and represses its transcriptional activity
Q53626183Unique dietary-related mouse model of colitis.
Q26830163eIF5A isoforms and cancer: two brothers for two functions?
Q35689748p53 targets identified by protein expression profiling

Search more.