Regulation of Hoxb2 by APL-associated PLZF protein

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Regulation of Hoxb2 by APL-associated PLZF protein is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1008133756
P356DOI10.1038/SJ.ONC.1206328
P698PubMed publication ID12802276
P5875ResearchGate publication ID10712601

P50authorFabien GuidezQ37381183
Arthur ZelentQ95995847
P2093author name stringLouise Howell
Robb Krumlauf
Sarah Ivins
Kieran Pemberton
P2860cites workCrystal structure of the BTB domain from PLZFQ22003945
Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion proteinQ24308811
A SNARE involved in protein transport through the Golgi apparatusQ24322596
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger proteinQ24523980
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptorsQ24563942
Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemiaQ24597732
SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor α (RARα) and PLZF-RARα oncoproteins associated with acute promyelocytic leukemiaQ24653689
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cellsQ27860599
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringQ27861072
Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrainQ28143128
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALLQ28254962
Inhibition of transcriptional regulator Yin-Yang-1 by association with c-MycQ28257537
Role of the histone deacetylase complex in acute promyelocytic leukaemiaQ28263534
Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF proteinQ28273724
Components of the SMRT Corepressor Complex Exhibit Distinctive Interactions with the POZ Domain Oncoproteins PLZF, PLZF-RARα, and BCL-6Q28284917
The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentationQ28505421
Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crestQ28506270
ROG, repressor of GATA, regulates the expression of cytokine genesQ28509186
A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector geneQ28593109
Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrainQ28594355
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemiaQ29616211
Altered Hox expression and segmental identity in Mll-mutant miceQ29620391
In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functionsQ33965235
Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrainQ34580344
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factorQ34997317
Effects ofHOX homeobox genes in blood cell differentiationQ38341754
DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancementQ39002684
Molecular mechanisms of segmental patterning in the vertebrate hindbrain and neural crestQ40621773
Oncogenic Transcription Factors in the Human Acute LeukemiasQ41628889
Lineage and stage specific expression of HOX 1 genes in the human hematopoietic systemQ41634022
Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cellsQ41724610
Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A.Q42819246
The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domainQ53445195
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectZinc finger and BTB domain containing 16Q11705457
negative regulation of transcription, DNA-templatedQ14633919
P304page(s)3685-3697
P577publication date2003-06-01
P1433published inOncogeneQ1568657
P1476titleRegulation of Hoxb2 by APL-associated PLZF protein
P478volume22

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cites work (P2860)
Q33625889A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?
Q34787845A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
Q28751687AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukemia
Q39734794Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells.
Q38927009Broad-complex, tramtrack, and bric-à-brac (BTB) proteins: Critical regulators of development
Q38671588Concise Review: Balancing Stem Cell Self-Renewal and Differentiation with PLZF.
Q36959950Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.
Q33523241EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans
Q24305158Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle
Q39533666Evidence for the transmission of neoplastic properties from transformed to normal human stem cells.
Q33863009Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.
Q37054486Identification of Novel EZH2 Targets Regulating Osteogenic Differentiation in Mesenchymal Stem Cells
Q61444977PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Q39855670PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.
Q24301491Protein interactions of the transcription factor Hoxa1
Q36276965RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia
Q37103871RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells
Q50098940Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity.
Q36176648Repression of kit expression by Plzf in germ cells
Q53539317Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters
Q24298449The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties
Q38041096Transcriptional networks in liver and intestinal development
Q33952249Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells
Q42738360Understanding PLZF: two transcriptional targets, REDD1 and smooth muscle α-actin, define new questions in growth control, senescence, self-renewal and tumor suppression

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