Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer

scientific article

Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1053/J.GASTRO.2006.07.020
P3181OpenCitations bibliographic resource ID3735604
P698PubMed publication ID17030191

P2093author name stringYick-Pang Ching
Judy W P Yam
David W Chan
Irene O L Ng
Chung-Yiu Chan
P2860cites workDIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stabilityQ22010042
Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding proteinQ24290612
HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencingQ24319786
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-cateninQ24534109
The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discsQ24599652
Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liverQ24680214
Cyclin is degraded by the ubiquitin pathwayQ28131704
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1Q28214701
Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transductionQ28218289
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signalingQ28613827
Wnt signaling: a common theme in animal developmentQ29547527
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathwaysQ29614619
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cellsQ29618245
Whose end is destruction: cell division and the anaphase-promoting complexQ29618257
Linking colorectal cancer to Wnt signalingQ29619810
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleusQ29620188
The Wnt signaling pathway and its role in tumor developmentQ34192072
beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.Q34302259
Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafishQ38352359
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.Q38520593
Wnt signaling: why is everything so negative?Q38529134
The prickle-related gene in vertebrates is essential for gastrulation cell movementsQ39750801
Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpressionQ40625644
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cellsQ42823306
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolismQ44226601
Beta-catenin/Tcf-1-mediated transactivation of cyclin D1 promoter is negatively regulated by thyroid hormoneQ44570386
Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancersQ47806576
Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.Q52021885
Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysisQ58739892
Prognostic significance of pathologic features of hepatocellular carcinoma. A multivariate analysis of 278 patientsQ71067081
Destruction with a box: substrate recognition by the anaphase-promoting complexQ75292418
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectliver cancerQ623031
protein ubiquitinationQ3547638
negative regulation of canonical Wnt signaling pathwayQ14860027
Dishevelled segment polarity protein 3Q21113750
Prickle planar cell polarity protein 1Q21118057
P304page(s)1218-27
P577publication date2006-10-01
P1433published inGastroenterologyQ4039279
P1476titlePrickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer
P478volume131

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cites work (P2860)
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