| P50 | author | Patrick O. Humbert | Q54591963 |
| | Helen B Pearson | Q57040683 |
| P2093 | author name string | Nathan J Gödde | |
| | Lorey K Smith | |
| P2860 | cites work | The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells | Q24296824 |
| | KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer | Q24297151 |
| | Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity | Q24297858 |
| | Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer | Q24306388 |
| | Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt | Q24307722 |
| | Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma | Q24319145 |
| | Epithelial cell polarity: a major gatekeeper against cancer? | Q24635870 |
| | Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers | Q24671334 |
| | Identification of Tetratricopeptide Repeat 1 as an Adaptor Protein That Interacts with Heterotrimeric G Proteins and the Small GTPase Ras | Q24673386 |
| | Differential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issues | Q27015135 |
| | Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland | Q27315980 |
| | Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis | Q27348603 |
| | Inhibition of Wnt signaling by Dishevelled PDZ peptides | Q27653983 |
| | Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes | Q27684030 |
| | Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma | Q28141888 |
| | Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1 | Q28189311 |
| | Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis | Q28252777 |
| | Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase | Q28258611 |
| | Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling | Q28287899 |
| | Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development | Q28507073 |
| | Lkb1 deficiency causes prostate neoplasia in the mouse | Q28592491 |
| | Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape | Q28593521 |
| | LKB1 modulates lung cancer differentiation and metastasis | Q30080027 |
| | Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. | Q30370835 |
| | Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis | Q30416351 |
| | The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis | Q30437640 |
| | Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. | Q30497855 |
| | Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells | Q31056323 |
| | FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders | Q33270390 |
| | Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL. | Q33551348 |
| | The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment | Q33570990 |
| | PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis | Q34038395 |
| | Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. | Q34155815 |
| | The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer | Q34169188 |
| | LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling | Q34279063 |
| | Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes | Q34336084 |
| | Epithelial junctions maintain tissue architecture by directing planar spindle orientation. | Q34358882 |
| | Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer | Q34426010 |
| | Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation | Q34460559 |
| | Two novel mutations and a new STK11/LKB1 gene isoform in Peutz-Jeghers patients. | Q34525216 |
| | Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation | Q34527075 |
| | Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction | Q34533191 |
| | LKB1-dependent signaling pathways | Q34535140 |
| | Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. | Q34546258 |
| | Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways | Q34602408 |
| | Protein kinase Cι expression and oncogenic signaling mechanisms in cancer. | Q34787801 |
| | Asymmetric cell divisions promote Notch-dependent epidermal differentiation | Q34796271 |
| | Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis | Q34942127 |
| | SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia | Q35572506 |
| | AMP-activated protein kinase regulates the assembly of epithelial tight junctions | Q35768585 |
| | Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity | Q35787307 |
| | Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma | Q35800124 |
| | Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity. | Q35893646 |
| | ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy | Q35971763 |
| | Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. | Q35997586 |
| | Tumor suppressors Sav/Scrib and oncogene Ras regulate stem-cell transformation in adult Drosophila malpighian tubules | Q36081389 |
| | Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways | Q36486608 |
| | Function and cancer genomics of FAT family genes (review) | Q36642936 |
| | c-Myc phosphorylation by PKCζ represses prostate tumorigenesis | Q36781982 |
| | Polarity proteins as regulators of cell junction complexes: implications for breast cancer | Q36828937 |
| | CD74-dependent deregulation of the tumor suppressor scribble in human epithelial and breast cancer cells. | Q36879247 |
| | Cell polarity in development and cancer. | Q36925556 |
| | Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo | Q37033601 |
| | Tight junction proteins: from barrier to tumorigenesis. | Q37118065 |
| | Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module | Q37333588 |
| | Upsides and downsides to polarity and asymmetric cell division in leukemia. | Q37333623 |
| | scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila | Q37367551 |
| | Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse | Q37368319 |
| | Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis | Q37373237 |
| | PKCι maintains a tumor-initiating cell phenotype that is required for ovarian tumorigenesis. | Q37466903 |
| | Targeting the LKB1 tumor suppressor | Q37506032 |
| | Crumbs3 is essential for proper epithelial development and viability | Q37546005 |
| | Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy | Q37578113 |
| | Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells | Q37593637 |
| | Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer. | Q37616060 |
| | Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions. | Q37749618 |
| | CD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease | Q37826194 |
| | Pointing in the right direction: new developments in the field of planar cell polarity. | Q37866626 |
| | Epithelial cell polarity, stem cells and cancer | Q37968480 |
| | The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man. | Q38038640 |
| | Rewiring cell polarity signaling in cancer | Q38196268 |
| | Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control | Q40216411 |
| | Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes | Q40230487 |
| | Suppression of progression and metastasis of established colon tumors in mice by intravenous delivery of short interfering RNA targeting KITENIN, a metastasis-enhancing protein | Q40365723 |
| | Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity | Q40402576 |
| | Small-molecule inhibitors at the PSD-95/nNOS interface have antidepressant-like properties in mice. | Q41859954 |
| | Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. | Q42522587 |
| | Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex | Q42811211 |
| | Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions | Q43121393 |
| | Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster | Q47072023 |
| | Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. | Q47072687 |
| | Therapeutic antitumor efficacy of monoclonal antibody against Claudin-4 for pancreatic and ovarian cancers. | Q51778516 |
| | High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence. | Q51808809 |
| | Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells. | Q52580604 |
| | Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo. | Q53081543 |
| | Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis. | Q53145549 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 249-257 | |
| P577 | publication date | 2014-08-30 | |
| P1433 | published in | Experimental Cell Research | Q1524289 |
| P1476 | title | Dissecting the role of polarity regulators in cancer through the use of mouse models | |
| P478 | volume | 328 | |