Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction

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Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.C200686200
P698PubMed publication ID12719437
P5875ResearchGate publication ID10784350

P50authorJürgen KnoblichQ1717362
Stephen M. LanierQ54867228
Dara DunicanQ57339427
Joe B BlumerQ57339491
P2093author name stringYuri K Peterson
Michael L Bernard
Peter Chung
Jun-ichi Nezu
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A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarityQ34530696
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Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteinsQ40847438
A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in DrosophilaQ42486222
The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in DrosophilaQ42508762
Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous systemQ42511782
Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localizationQ47881793
Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteinsQ48057802
Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryosQ48561935
Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patientsQ78109607
Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signalingQ22010510
Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2Q24308852
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptorsQ24336174
Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunitsQ27638907
A serine/threonine kinase gene defective in Peutz-Jeghers syndromeQ28119198
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowthQ28211693
A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organizationQ28214962
A mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKSQ28288020
Receptor-independent activators of heterotrimeric G-protein signaling pathwaysQ28569590
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinaseQ28593509
Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.Q30661459
Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.Q30915703
Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposisQ34066238
Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.Q34113092
Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i.Q34171369
Asymmetric cell division during animal developmentQ34286348
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)23217-23220
P577publication date2003-04-28
P1433published inJournal of Biological ChemistryQ867727
P1476titleInteraction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction
P478volume278

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cites work (P2860)
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