scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1016975209 |
P356 | DOI | 10.1007/S00438-005-1124-Y |
P698 | PubMed publication ID | 15731909 |
P5875 | ResearchGate publication ID | 8001583 |
P50 | author | Stilianos Antonarakis | Q15429287 |
Christelle Borel | Q91710837 | ||
P2093 | author name string | Nathalie Lin-Marq | |
P2860 | cites work | Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade | Q21245891 |
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death | Q24291382 | ||
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow | Q24291392 | ||
LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1 | Q24291996 | ||
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm | Q24296287 | ||
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD | Q24305094 | ||
Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins | Q24307824 | ||
Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin | Q24310542 | ||
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo | Q24531930 | ||
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes | Q24534395 | ||
Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity | Q24539769 | ||
GSK-3: tricks of the trade for a multi-tasking kinase | Q24624069 | ||
The Wnts | Q24802301 | ||
Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases | Q27939305 | ||
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome | Q28119198 | ||
Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1 | Q28189311 | ||
LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest | Q28205561 | ||
LKB1--a master tumour suppressor of the small intestine and beyond | Q28208312 | ||
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth | Q28211693 | ||
Elastic fiber homeostasis requires lysyl oxidase-like 1 protein | Q28240976 | ||
Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene | Q28250528 | ||
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase | Q28258611 | ||
LKB1 tumor suppressor protein: PARtaker in cell polarity | Q28265461 | ||
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis | Q28300857 | ||
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366 | Q28504452 | ||
Causal relationship between the loss of RUNX3 expression and gastric cancer | Q28509530 | ||
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity | Q28568803 | ||
Haploinsufficiency of the mouse Forkhead Box f1 gene causes defects in gall bladder development | Q28587688 | ||
Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function | Q28591207 | ||
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase | Q28593509 | ||
Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice | Q28594689 | ||
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade | Q28610414 | ||
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector | Q29547503 | ||
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene | Q29616540 | ||
Caught up in a Wnt storm: Wnt signaling in cancer | Q29617494 | ||
Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex | Q31152974 | ||
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. | Q33643620 | ||
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways | Q33814311 | ||
Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis | Q34066238 | ||
Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis | Q34156001 | ||
Regulation of GSK-3: a cellular multiprocessor | Q34299875 | ||
Increased risk for cancer in patients with the Peutz-Jeghers syndrome | Q34472625 | ||
Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest | Q34504424 | ||
The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry | Q34507504 | ||
Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome. | Q34512116 | ||
Very high risk of cancer in familial Peutz-Jeghers syndrome | Q34512286 | ||
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice | Q34522435 | ||
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation | Q34527075 | ||
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity | Q34530696 | ||
Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction | Q34533191 | ||
LKB1, a protein kinase regulating cell proliferation and polarity | Q34534892 | ||
LKB1 (XEEK1) regulates Wnt signalling in vertebrate development | Q34536922 | ||
Correlation of Staining for LKB1 and COX-2 in Hamartomatous Polyps and Carcinomas from Patients with Peutz–Jeghers Syndrome | Q34543277 | ||
Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. | Q34546258 | ||
Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos | Q34733393 | ||
Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. | Q34756366 | ||
Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis | Q35210772 | ||
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium | Q39895829 | ||
Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways. | Q40673025 | ||
Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients. | Q40674603 | ||
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome | Q41022988 | ||
Immunolocalization of beta catenin in intestinal polyps of Peutz-Jeghers and juvenile polyposis syndromes | Q42160195 | ||
Reduction of Cell Surface Fibronectin (LETS Protein) Correlates with Tumorigenicity of Hamster Fibroblasts Transformed by Herpes Simplex Virus Type 2 | Q45803883 | ||
Smooth muscle expresses bone morphogenetic protein (Vgr-1/BMP-6) in human fetal intestine | Q46180828 | ||
Analysis of high density expression microarrays with signed-rank call algorithms | Q48611725 | ||
Robust estimators for expression analysis | Q48611734 | ||
Growth and molecular profile of lung cancer cells expressing ectopic LKB1: down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway. | Q54783174 | ||
High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors | Q73172777 | ||
Perinatal hypoxia-ischemia decreased neuronal but increased cerebral vascular endothelial IGFBP3 expression | Q73530524 | ||
Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients | Q78109607 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | negative regulation of canonical Wnt signaling pathway | Q14860027 |
Serine/threonine kinase 11 | Q21109306 | ||
Serine/threonine kinase 11 | Q21991188 | ||
P304 | page(s) | 184-96 | |
P577 | publication date | 2005-04-01 | |
P1433 | published in | Molecular Genetics and Genomics | Q15753424 |
P1476 | title | Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling | |
P478 | volume | 273 |
Q35094301 | Endopancreatic bile duct cholangiocarcinoma in a patient with peutz-jeghers syndrome. |
Q35853581 | Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. |
Q38829991 | GSK-3β controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells |
Q54449617 | Immunohistological evidence for Wnt-signaling activation in Peutz-Jeghers polyposis. |
Q24312214 | Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity |
Q55342073 | Involvement of NADPH Oxidase 1 in Liver Kinase B1-Mediated Effects on Tumor Angiogenesis and Growth. |
Q42801148 | Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1alpha and UCP-1 gene expression in brown adipocytes. |
Q38994951 | LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT. |
Q24655120 | LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome |
Q37333592 | LKB1; linking cell structure and tumor suppression |
Q50314061 | Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice |
Q36016140 | Mucosal pigmentation caused by imatinib: report of three cases |
Q81904177 | Osteogenic tumours in Lkb1-deficient mice |
Q81993570 | Pigmentation of the hard palate |
Q38838114 | RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A. |
Q41677991 | Specific deletion of LKB1/Stk11 in the Müllerian duct mesenchyme drives hyperplasia of the periurethral stroma and tumorigenesis in male mice |
Q34409196 | The biology of hyperpigmentation syndromes |
Q39097606 | The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3β activity in cell growth of esophageal carcinoma |
Q54486535 | Two variants in STK11 gene in Chinese patients with Peutz-Jeghers syndrome. |
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