| scholarly article | Q13442814 |
| P50 | author | Stephen M. Lanier | Q54867228 |
| Joe B Blumer | Q57339491 | ||
| P2093 | author name string | J. B. Blumer | |
| S. M. Lanier | |||
| P2860 | cites work | Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s) | Q74016638 |
| Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8 | Q80186423 | ||
| Girdin protein: a new potential distant metastasis predictor of breast cancer | Q82676566 | ||
| GPSM2 and Chudley-McCullough syndrome: a Dutch founder variant brought to North America | Q86392474 | ||
| Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling | Q22010510 | ||
| Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration | Q22254214 | ||
| Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles | Q24297434 | ||
| Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins | Q24313402 | ||
| The cationic region of Rhes mediates its interactions with specific Gbeta subunits | Q24316984 | ||
| Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity | Q24317318 | ||
| Akt/PKB regulates actin organization and cell motility via Girdin/APE | Q24319781 | ||
| Crystal structure of the β2 adrenergic receptor-Gs protein complex | Q24635327 | ||
| Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts | Q24670347 | ||
| Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits | Q27638907 | ||
| LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways | Q27671529 | ||
| Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN) | Q27675508 | ||
| Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions | Q27676217 | ||
| An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs | Q27684596 | ||
| Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor | Q27934014 | ||
| Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi | Q28115003 | ||
| Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON | Q28138253 | ||
| Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes | Q28201057 | ||
| Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor | Q28201257 | ||
| Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases | Q28212840 | ||
| A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization | Q28214962 | ||
| Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue | Q28218928 | ||
| The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors | Q28238833 | ||
| Dexamethasone rapidly induces a novel ras superfamily member-related gene in AtT-20 cells | Q28260734 | ||
| The Ras-related protein AGS1/RASD1 suppresses cell growth | Q28265751 | ||
| Specific in vivo binding of activator of G protein signalling 1 to the Gbeta1 subunit | Q28277087 | ||
| Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits | Q36673368 | ||
| Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum | Q36680959 | ||
| Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations | Q36729833 | ||
| Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1). | Q36742217 | ||
| Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking. | Q36747977 | ||
| Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors | Q36773326 | ||
| Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function | Q36796699 | ||
| A truncating mutation in GPSM2 is associated with recessive non-syndromic hearing loss | Q36855007 | ||
| Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma | Q36858644 | ||
| Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity | Q37013755 | ||
| Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network. | Q37099770 | ||
| GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling | Q37117635 | ||
| Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association | Q37408332 | ||
| The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase | Q37598759 | ||
| Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. | Q37880248 | ||
| Ric-8 regulation of heterotrimeric G proteins | Q38079286 | ||
| Signalling bias in new drug discovery: detection, quantification and therapeutic impact. | Q38081692 | ||
| Efficacy and ligand bias at the μ-opioid receptor | Q38104365 | ||
| Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. | Q38334695 | ||
| Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin). | Q36433811 | ||
| G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease | Q36504457 | ||
| Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex | Q36567861 | ||
| Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors. | Q36579455 | ||
| Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors. | Q36579634 | ||
| Involvement of Girdin in the determination of cell polarity during cell migration | Q28483426 | ||
| G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis | Q28509151 | ||
| Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43) | Q28513014 | ||
| Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats | Q28566486 | ||
| Receptor-independent activators of heterotrimeric G-protein signaling pathways | Q28569590 | ||
| Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha | Q28572549 | ||
| Rhes: A striatal-specific Ras homolog related to Dexras1 | Q28578297 | ||
| The RGS14 GoLoco domain discriminates among Galphai isoforms | Q28584345 | ||
| A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis | Q28585704 | ||
| G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth | Q28585892 | ||
| Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety | Q28586019 | ||
| Nucleotide exchange factor RIC-8 is indispensable in mammalian early development | Q28589364 | ||
| Rhes is involved in striatal function | Q28589966 | ||
| Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells | Q28590088 | ||
| Genome-wide association study identifies three novel loci for type 2 diabetes | Q29417014 | ||
| Asymmetric cell divisions promote stratification and differentiation of mammalian skin | Q29620393 | ||
| LGN regulates mitotic spindle orientation during epithelial morphogenesis | Q30434467 | ||
| A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics | Q30437593 | ||
| Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle | Q30495284 | ||
| Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells | Q30538070 | ||
| Structure-function of the G protein-coupled receptor superfamily | Q30576993 | ||
| A spindle-independent cleavage furrow positioning pathway. | Q30578547 | ||
| Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3. | Q30981890 | ||
| Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma | Q33231433 | ||
| An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy | Q33528947 | ||
| Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable. | Q33705006 | ||
| A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration | Q33799957 | ||
| Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior | Q33841606 | ||
| A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate | Q33948589 | ||
| Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. | Q33960515 | ||
| Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai | Q33966889 | ||
| Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis. | Q34113092 | ||
| Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD. | Q34124149 | ||
| Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes | Q34133413 | ||
| Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo | Q38353471 | ||
| GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression | Q38974569 | ||
| A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration | Q39209451 | ||
| The regulation of Rasd1 expression by glucocorticoids and prolactin controls peripartum maternal insulin secretion | Q39330905 | ||
| A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. | Q39341462 | ||
| Ras dexamethasone-induced protein 1 is a modulator of hormone secretion in the volume overloaded heart | Q39381503 | ||
| The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function | Q39616042 | ||
| Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells | Q39686834 | ||
| Differential effects of AGS3 expression on D(2L) dopamine receptor-mediated adenylyl cyclase signaling | Q39906615 | ||
| The monomeric G proteins AGS1 and Rhes selectively influence Galphai-dependent signaling to modulate N-type (CaV2.2) calcium channels. | Q39936146 | ||
| Dexras1 blocks receptor-mediated heterologous sensitization of adenylyl cyclase 1. | Q40418054 | ||
| Dexras1 inhibits adenylyl cyclase | Q40578641 | ||
| Dexras1/AGS-1, a steroid hormone-induced guanosine triphosphate-binding protein, inhibits 3',5'-cyclic adenosine monophosphate-stimulated secretion in AtT-20 corticotroph cells | Q40805615 | ||
| Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins | Q40847438 | ||
| Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease | Q41196900 | ||
| Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia | Q42029608 | ||
| Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3. | Q42147924 | ||
| Drosophila GoLoco-protein Pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling | Q42184011 | ||
| G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors | Q42481073 | ||
| Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division | Q42485369 | ||
| Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins | Q42485373 | ||
| A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila | Q42486222 | ||
| Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. | Q42495400 | ||
| Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system | Q42511782 | ||
| Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina | Q42807828 | ||
| IGF-1 activates a cilium-localized noncanonical Gβγ signaling pathway that regulates cell-cycle progression | Q42957171 | ||
| Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. | Q43271908 | ||
| AGS3 and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3 blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i). | Q44730636 | ||
| Dexras1 potentiates photic and suppresses nonphotic responses of the circadian clock | Q45038419 | ||
| RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans | Q45103218 | ||
| The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors | Q45205316 | ||
| Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. | Q46854784 | ||
| Control of embryonic spindle positioning and Galpha activity by C. elegans RIC-8. | Q47069601 | ||
| Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins | Q47069999 | ||
| Tre1 GPCR signaling orients stem cell divisions in the Drosophila central nervous system | Q47071130 | ||
| Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila. | Q47072851 | ||
| Girdin locates in centrosome and midbody and plays an important role in cell division | Q47424908 | ||
| Receptor- and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation. | Q47735328 | ||
| Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization | Q47881793 | ||
| The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway | Q47922889 | ||
| Mouse dexamethasone-induced RAS protein 1 gene is expressed in a circadian rhythmic manner in the suprachiasmatic nucleus. | Q48393721 | ||
| The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells. | Q51803692 | ||
| GPSM2 mutations in Chudley-McCullough syndrome. | Q55154813 | ||
| The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells. | Q34184261 | ||
| Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos | Q34197454 | ||
| Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor. | Q34232074 | ||
| Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion | Q34319297 | ||
| A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine | Q34321618 | ||
| Return of the GDI: the GoLoco motif in cell division. | Q34326049 | ||
| Casting a wider net: whole-cell assays to capture varied and biased signaling | Q34350478 | ||
| RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos | Q34358248 | ||
| Expression of GIV/Girdin, a metastasis‐related protein, predicts patient survival in colon cancer | Q34502681 | ||
| Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf). | Q34509373 | ||
| Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction | Q34533191 | ||
| Attenuation of Rhes activity significantly delays the appearance of behavioral symptoms in a mouse model of Huntington's disease | Q34562244 | ||
| A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals | Q34611677 | ||
| Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. | Q34748737 | ||
| Asymmetric cell divisions promote Notch-dependent epidermal differentiation | Q34796271 | ||
| Rhes and AGS1/Dexras1 affect signaling by dopamine D1 receptors through adenylyl cyclase | Q34798869 | ||
| Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator | Q34978973 | ||
| Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents | Q35003246 | ||
| Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor | Q35011100 | ||
| Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin | Q35013054 | ||
| Accessory proteins for G protein-signaling systems: activators of G protein signaling and other nonreceptor proteins influencing the activation state of G proteins | Q35140419 | ||
| AGS-3 alters Caenorhabditis elegans behavior after food deprivation via RIC-8 activation of the neural G protein G αo. | Q35180330 | ||
| 'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass? | Q35210020 | ||
| G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cells | Q35515403 | ||
| G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gβ and Gαi protein subunits | Q35763023 | ||
| A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegans | Q35965179 | ||
| Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling. | Q35995003 | ||
| GPSM2 mutations cause the brain malformations and hearing loss in Chudley-McCullough syndrome | Q36017073 | ||
| Endomorphin-2: a biased agonist at the μ-opioid receptor. | Q36105495 | ||
| A specific role of AGS3 in the surface expression of plasma membrane proteins | Q36156809 | ||
| Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways | Q36207326 | ||
| Accessory proteins for G proteins: partners in signaling. | Q36364667 | ||
| Ligand-directed signalling within the opioid receptor family | Q36382935 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 388-396 | |
| P577 | publication date | 2014-03-01 | |
| P1433 | published in | Molecular Pharmacology | Q1943386 |
| P1476 | title | Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad | |
| P478 | volume | 85 |
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