Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable.

scientific article

Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.01018-09
P932PMC publication ID2832490
P698PubMed publication ID20065032
P5875ResearchGate publication ID40907621

P50authorStephen M. LanierQ54867228
Joe B BlumerQ57339491
Violaine SimonQ73536780
Dzwokai MaQ88592713
P2093author name stringAli Vural
Ningfei An
Sadik Oner
P2860cites workThe deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stressQ24301895
Design of Stable α-Helical Arrays from an Idealized TPR MotifQ27641184
The tetratricopeptide repeat: a structural motif mediating protein-protein interactionsQ28145758
Aggresome formation and neurodegenerative diseases: therapeutic implicationsQ28265926
Aggresomes: a cellular response to misfolded proteinsQ28292275
Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted ratsQ28566486
Receptor-independent activators of heterotrimeric G-protein signaling pathwaysQ28569590
The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteinsQ28577307
Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neuronsQ28577675
G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowthQ28585892
Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cellsQ28590088
Aggresomes, inclusion bodies and protein aggregationQ29615253
A critical role for CHIP in the aggresome pathwayQ30485241
Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.Q30661459
Asymmetric divisions, aggresomes and apoptosisQ33621958
Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behaviorQ33841606
Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formationQ33897200
The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formationQ33934283
Regulation of inducible nitric oxide synthase by aggresome formationQ33935202
Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.Q34113092
The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.Q34184261
Membrane targeting and asymmetric localization of Drosophila partner of inscuteable are discrete steps controlled by distinct regions of the protein.Q34280940
Hassles with taking out the garbage: aggravating aggresomes.Q34637179
An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liverQ35669855
Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.Q35995003
A specific role of AGS3 in the surface expression of plasma membrane proteinsQ36156809
Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.Q36747977
Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular functionQ36796699
Nucleus accumbens AGS3 expression drives ethanol seeking through G betagammaQ36858644
G protein betagamma subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry.Q36978627
G betagamma binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activityQ40362637
Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteinsQ40847438
Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15.Q41150346
Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localizationQ41607089
Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.Q42147924
G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitorsQ42481073
A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in DrosophilaQ42486222
Emerging role for autophagy in the removal of aggresomes in Schwann cells.Q44662067
The missing linker: an unexpected role for a histone deacetylaseQ44702958
G protein betagamma directly regulates SNARE protein fusion machinery for secretory granule exocytosis.Q46391444
Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif.Q51604509
The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells.Q51803692
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1528-1540
P577publication date2010-01-11
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleDistribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable
P478volume30

Reverse relations

cites work (P2860)
Q36738441Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection
Q26999408Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad
Q30603352Canonical and noncanonical g-protein signaling helps coordinate actin dynamics to promote macrophage phagocytosis of zymosan
Q33675851Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)
Q39906615Differential effects of AGS3 expression on D(2L) dopamine receptor-mediated adenylyl cyclase signaling
Q35897877Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gαi G-Protein Regulatory Motif Complex
Q37880248Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.
Q36014957Gαi3-Dependent Inhibition of JNK Activity on Intracellular Membranes
Q33543785Identification of a deubiquitinating enzyme as a novel AGS3-interacting protein
Q36079978Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance.
Q35060770Normal autophagic activity in macrophages from mice lacking Gαi3, AGS3, or RGS19.
Q34232074Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.
Q36579455Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.
Q58565715Role of G-proteins and S/T phosphorylation sites in the transition of Activator of G-Protein signaling 3 to cell puncta
Q37598759The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase
Q37099770Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.

Search more.