| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2006PNAS..10317272Z |
| P356 | DOI | 10.1073/PNAS.0608531103 |
| P932 | PMC publication ID | 1859922 |
| P698 | PubMed publication ID | 17088526 |
| P5875 | ResearchGate publication ID | 6707787 |
| P2093 | author name string | Li Zhang | |
| Michael J Caplan | |||
| Ji Li | |||
| Lawrence H Young | |||
| P2860 | cites work | Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells | Q44693355 |
| Sulfite-mediated oxidative stress in kidney cells | Q44724710 | ||
| Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease | Q45162599 | ||
| 5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms | Q71824256 | ||
| Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase | Q72210218 | ||
| Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade | Q21245891 | ||
| The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 | Q22254751 | ||
| Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures | Q24290938 | ||
| LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 | Q24310603 | ||
| Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits | Q24321754 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases | Q27939305 | ||
| A serine/threonine kinase gene defective in Peutz-Jeghers syndrome | Q28119198 | ||
| Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells | Q28239348 | ||
| Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase | Q28258611 | ||
| The LKB1 tumor suppressor negatively regulates mTOR signaling | Q28272728 | ||
| Functional domains of the alpha1 catalytic subunit of the AMP-activated protein kinase | Q28291824 | ||
| Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase | Q28567006 | ||
| LKB1 is the upstream kinase in the AMP-activated protein kinase cascade | Q28610414 | ||
| 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? | Q29618095 | ||
| Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. | Q30436000 | ||
| The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit | Q34099494 | ||
| Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. | Q34438345 | ||
| The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry | Q34507504 | ||
| A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity | Q34530696 | ||
| Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. | Q34546258 | ||
| Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity. | Q34556342 | ||
| Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase | Q35003564 | ||
| The molecular physiology of tight junction pores | Q35952151 | ||
| Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton | Q36322073 | ||
| AMPK: a key sensor of fuel and energy status in skeletal muscle | Q36380591 | ||
| The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases | Q40404608 | ||
| PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. | Q40456149 | ||
| Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome | Q41022988 | ||
| Polarized monolayers formed by epithelial cells on a permeable and translucent support | Q41233493 | ||
| Interaction of calcium with plasma membrane of epithelial (MDCK) cells during junction formation | Q41610160 | ||
| Role of calcium in tight junction formation between epithelial cells | Q41712997 | ||
| The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells | Q42570947 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 46 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 17272-17277 | |
| P577 | publication date | 2006-11-06 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | AMP-activated protein kinase regulates the assembly of epithelial tight junctions | |
| P478 | volume | 103 |
| Q47307186 | (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. |
| Q28611264 | A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression |
| Q27314508 | A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics |
| Q33409118 | AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts |
| Q35641071 | AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic |
| Q30426934 | AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane |
| Q42364792 | AMP-activated protein kinase - not just an energy sensor. |
| Q24338892 | AMP-activated protein kinase downregulates Kv7.1 cell surface expression |
| Q37429741 | AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin |
| Q38024322 | AMP-activated protein kinase in the control of cardiac metabolism and remodeling |
| Q37459893 | AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function |
| Q41567299 | AMP-activated protein kinase: a therapeutic target in intestinal diseases. |
| Q26865723 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function |
| Q29618101 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy |
| Q53322508 | AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. |
| Q38712389 | AMPK negatively regulates tensin-dependent integrin activity. |
| Q36920118 | AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization |
| Q90649869 | Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin |
| Q91985663 | Activation of the Ca2+ sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3 |
| Q37309886 | Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane |
| Q34718458 | Adiponectin increases secretion of rat submandibular gland via adiponectin receptors-mediated AMPK signaling |
| Q52688725 | Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions. |
| Q36283354 | Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis |
| Q35050467 | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 |
| Q34534129 | Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway |
| Q37204613 | Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 |
| Q43067512 | Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers. |
| Q30661551 | CaMKII regulates the strength of the epithelial barrier. |
| Q38245149 | Cell fate regulation during preimplantation development: a view of adhesion-linked molecular interactions |
| Q35914155 | Cellular mechanism of bile acid-accelerated hepatocyte polarity |
| Q38168765 | Cellular polarity in aging: role of redox regulation and nutrition. |
| Q37435101 | Chapter 3: acquisition of membrane polarity in epithelial tube formation patterns, signaling pathways, molecular mechanisms, and disease. |
| Q38928944 | Claudin-4 is required for AMPK-modulated paracellular permeability in submandibular gland cells |
| Q33687560 | Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro. |
| Q42118938 | Connecting metabolism to intestinal barrier function: The role of leptin |
| Q36820101 | Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization |
| Q102059062 | Crosstalk between mechanotransduction and metabolism |
| Q55078475 | Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. |
| Q38245421 | Dissecting the role of polarity regulators in cancer through the use of mouse models. |
| Q41199559 | Dystroglycan and AMP kinase: polarity's protectors when the power goes out. |
| Q40185886 | Effect of dietary nonstructural carbohydrate content on activation of 5'-adenosine monophosphate-activated protein kinase in liver, skeletal muscle, and digital laminae of lean and obese ponies |
| Q82978338 | Effects of n-3 polyunsaturated fatty acids on rat livers after partial hepatectomy via LKB1-AMPK signaling pathway |
| Q35016923 | Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth |
| Q26851833 | Emerging role of cell polarity proteins in breast cancer progression and metastasis |
| Q37968480 | Epithelial cell polarity, stem cells and cancer |
| Q37241585 | Epithelial junctions and polarity: complexes and kinases |
| Q91817427 | Establishing Boundaries: The Relationship That Exists between Intestinal Epithelial Cells and Gut-Dwelling Bacteria |
| Q39582504 | Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1β by suppressing AMP-activated protein kinase (AMPK) activation. |
| Q30578909 | Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK. |
| Q89138010 | GPR40 receptor activation promotes tight junction assembly in airway epithelial cells via AMPK-dependent mechanisms |
| Q91692304 | Gut microbiota metabolite regulation of host defenses at mucosal surfaces: implication in precision medicine |
| Q36972087 | Hepatocyte polarity |
| Q36253752 | Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction |
| Q41912916 | Ignoring matrix boundaries when the LKB1 master kinase is gone. |
| Q64982692 | Implications of AMPK in the Formation of Epithelial Tight Junctions. |
| Q37896565 | Insights from model organisms on the functions of the tumor suppressor protein LKB1: zebrafish chips in. |
| Q39904783 | Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells |
| Q53178021 | L-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells. |
| Q38034578 | LKB1 and AMP-activated protein kinase: regulators of cell polarity |
| Q37543834 | LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism |
| Q36119701 | LKB1 and AMPK maintain epithelial cell polarity under energetic stress |
| Q39026772 | LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies |
| Q36978341 | LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation |
| Q33916529 | LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo |
| Q37829489 | LKB1 loss of function studied in vivo |
| Q37811822 | LKB1 regulated pathways in lung cancer invasion and metastasis |
| Q37211374 | LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. |
| Q48569187 | LKB1 signaling in cephalic neural crest cells is essential for vertebrate head development |
| Q28280001 | LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain |
| Q37333592 | LKB1; linking cell structure and tumor suppression |
| Q44501125 | Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK. |
| Q37276934 | Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo |
| Q36486608 | Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways |
| Q28475263 | Lymphocytes Accelerate Epithelial Tight Junction Assembly: Role of AMP-Activated Protein Kinase (AMPK) |
| Q89104991 | Mechanisms linking mechanotransduction and cell metabolism |
| Q58774497 | Mechanisms regulating intestinal barrier integrity and its pathological implications |
| Q41110512 | Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1. |
| Q93204707 | Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ-mediated phosphorylation of occludin |
| Q38797366 | Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth |
| Q47100569 | Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. |
| Q42575812 | Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose |
| Q37824725 | Molecular mechanisms of tumor suppression by LKB1. |
| Q39908010 | Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes |
| Q40130513 | Occludin regulates glucose uptake and ATP production in pericytes by influencing AMP-activated protein kinase activity |
| Q57067836 | Ocular Manifestations of Emerging Flaviviruses and the Blood-Retinal Barrier |
| Q41982039 | Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms |
| Q35601616 | Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia |
| Q37396622 | Protection and Restitution of Gut Barrier by Probiotics: Nutritional and Clinical Implications |
| Q37350410 | Protein trafficking in polarized cells |
| Q34611758 | RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis |
| Q91645103 | Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function? |
| Q34129484 | Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1. |
| Q38196268 | Rewiring cell polarity signaling in cancer |
| Q42697966 | Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats |
| Q61803411 | Role of Dietary Lipids in Modulating Inflammation through the Gut Microbiota |
| Q37854547 | Role of LKB1-SAD/MARK pathway in neuronal polarization |
| Q92081710 | Role of Tricellular Tight Junction Protein Lipolysis-Stimulated Lipoprotein Receptor (LSR) in Cancer Cells |
| Q38594976 | Role of tight junctions in signal transduction: an update. |
| Q35175369 | Specific deletion of AMP-activated protein kinase (α1AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiology |
| Q35990220 | Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization |
| Q37506032 | Targeting the LKB1 tumor suppressor |
| Q24616273 | The AMPK signalling pathway coordinates cell growth, autophagy and metabolism |
| Q37886809 | The LKB1 complex-AMPK pathway: the tree that hides the forest |
| Q34345692 | The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells |
| Q29617506 | The LKB1-AMPK pathway: metabolism and growth control in tumour suppression |
| Q37824021 | The LKB1/AMPK polarity pathway |
| Q24595075 | The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK. |
| Q37715482 | The stress polarity pathway: AMPK 'GIV'-es protection against metabolic insults |
| Q89636468 | The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer |
| Q38222544 | The unique polarity phenotype of hepatocytes |
| Q47725186 | Treatment with AICAR inhibits blastocyst development, trophectoderm differentiation and tight junction formation and function in mice |
| Q44510337 | Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress |
| Q92533673 | Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions |
| Q53835631 | Wild jujube polysaccharides protect against experimental inflammatory bowel disease by enabling enhanced intestinal barrier function. |
| Q38862390 | miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene. |
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