PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130

scientific article

PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130 is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1016354374
P356DOI10.1038/CR.2010.56
P3181OpenCitations bibliographic resource ID4355467
P698PubMed publication ID20421892
P5875ResearchGate publication ID43346089

P50authorZhenhua ZouQ86825622
P2093author name stringYi Wang
Lei Li
Jun Qin
Tao Zhang
Lin Liu
Weimin Gong
Zhongwei Zhou
Ya Wen
Litao Sun
Xiaotian Sun
Shilai Bao
Shaoshi Guo
P2860cites workNegative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1HsQ22008487
The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formationQ24292939
GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distributionQ24305177
Coordination of golgin tethering and SNARE assembly: GM130 binds syntaxin 5 in a p115-regulated mannerQ24305336
PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginineQ24307732
PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase familyQ24310851
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPsQ24311843
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zetaQ24318811
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genesQ24563451
Characterization of a cis-Golgi matrix protein, GM130Q24672240
VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragmentsQ24677725
A role for giantin in docking COPI vesicles to Golgi membranesQ24683329
The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130Q24685935
The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activityQ27931859
Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1pQ27939495
Arginine methylation regulates the p53 responseQ28116284
The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi trafficQ28141461
Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase familyQ28142367
Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation PropertiesQ28201556
The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartmentQ28214965
The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated mannerQ28238101
GRASP65, a protein involved in the stacking of Golgi cisternaeQ28252739
Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosisQ28573476
The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repressionQ28585090
Arginine methylation an emerging regulator of protein functionQ29617311
Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumorsQ30851433
Reprogramming primordial germ cells into pluripotent stem cellsQ33379605
Golgins in the structure and dynamics of the Golgi apparatusQ34218887
Isolation of a matrix that binds medial Golgi enzymesQ34335605
Organellar proteomics reveals Golgi arginine dimethylationQ34360019
Golgi architecture and inheritanceQ34525643
Cell-cycle-specific Golgi fragmentation: how and why?Q35189422
SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in ArabidopsisQ35741779
Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphomaQ35941514
Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cellsQ36959982
Generation of primordial germ cells from pluripotent stem cellsQ37358132
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.Q37432768
Golgins and GRASPs: holding the Golgi togetherQ37512660
Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPsQ39665747
Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling.Q40464411
Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defectsQ40547899
A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system.Q41850628
Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiationQ42073882
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filamentsQ42861316
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stackQ46341560
The Sm-protein methyltransferase, dart5, is essential for germ-cell specification and maintenance.Q47072191
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cellsQ48547495
A cryptic Rab1-binding site in the p115 tethering proteinQ50336128
Structural integrity of the Golgi is temperature sensitive in conditional-lethal mutants with no detectable GM130.Q51838071
The highly conserved protein methyltransferase, Skb1, is a mediator of hyperosmotic stress response in the fission yeast Schizosaccharomyces pombe.Q54370032
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectGolgi apparatusQ83181
Golgi ribbon formationQ21111433
Protein arginine methyltransferase 5Q21130994
Golgin A2Q21172266
P304page(s)1023-33
P577publication date2010-09-01
P1433published inCell ResearchQ1524018
P1476titlePRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130
P478volume20

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cites work (P2860)
Q99710798ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration
Q34945684An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.
Q38337906Arabidopsis floral initiator SKB1 confers high salt tolerance by regulating transcription and pre-mRNA splicing through altering histone H4R3 and small nuclear ribonucleoprotein LSM4 methylation.
Q34279382Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing
Q26851594Arginine methyltransferases as novel therapeutic targets for breast cancer
Q58614576Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells
Q35626092Evolutionary emergence of a novel splice variant with an opposite effect on the cell cycle
Q38815850GM130 regulates epithelial-to-mesenchymal transition and invasion of gastric cancer cells via snail
Q92763241Golgi Structure and Function in Health, Stress, and Diseases
Q34476104Golgi post-translational modifications and associated diseases
Q33357384Histone H4R3 methylation catalyzed by SKB1/PRMT5 is required for maintaining shoot apical meristem
Q34107266Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5
Q36040610JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein
Q90402870LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity
Q37589927Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice
Q28506694MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway
Q36275660Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells
Q36796282Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer
Q89640752PRMT5 in gene regulation and hematologic malignancies
Q91943244PRMT5-dependent transcriptional repression of c-Myc target genes promotes gastric cancer progression
Q42702501Proliferative role of TRAF4 in breast cancer by upregulating PRMT5 nuclear expression
Q35191784Protein arginine methylation in parasitic protozoa
Q60924996Protein arginine methyltransferase 5 (PRMT5) dysregulation in cancer
Q24298151Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells
Q39326599Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade
Q37398814Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
Q37145814Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation
Q50705431SKB1/PRMT5-mediated histone H4R3 dimethylation of Ib subgroup bHLH genes negatively regulates iron homeostasis in Arabidopsis thaliana.
Q92763245Selected Golgi-Localized Proteins and Carcinogenesis: What Do We Know?
Q38642785Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity
Q37395704Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia
Q47390446The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
Q36548253Toxoplasma gondii Arginine Methyltransferase 1 (PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division.
Q35577094Versatility of PRMT5-induced methylation in growth control and development.
Q24298324srGAP2 Arginine Methylation Regulates Cell Migration and Cell Spreading through Promoting Dimerization

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