scholarly article | Q13442814 |
P2093 | author name string | Y Li | |
R Benezra | |||
P433 | issue | 5285 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Mitotic arrest deficient 2 like 1 | Q21132390 |
P304 | page(s) | 246-8 | |
P577 | publication date | 1996-10-11 | |
P1433 | published in | Science | Q192864 |
P1476 | title | Identification of a human mitotic checkpoint gene: hsMAD2 | |
P478 | volume | 274 |
Q28075699 | A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint |
Q22009372 | A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2 |
Q33997177 | A Subunit of the Anaphase-Promoting Complex Is a Centromere-Associated Protein in Mammalian Cells |
Q38846085 | A comprehensive analysis of CDC20 overexpression in common malignant tumors from multiple organs: its correlation with tumor grade and stage |
Q91970577 | A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division |
Q28144150 | A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2 |
Q39724395 | A mutation in NPS1/STH1, an essential gene encoding a component of a novel chromatin-remodeling complex RSC, alters the chromatin structure of Saccharomyces cerevisiae centromeres |
Q42533669 | A new Mad2-interacting domain of Cdc20 is critical for the function of Mad2-Cdc20 complex in the spindle assembly checkpoint |
Q37293039 | A quantitative systems view of the spindle assembly checkpoint |
Q36273802 | A role for mitogen-activated protein kinase in the spindle assembly checkpoint in XTC cells |
Q33862461 | A soybean cDNA encoding a chromatin-binding peptide inhibits mitosis of mammalian cells |
Q74082926 | Aberrant expression of cell-cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability |
Q45952803 | Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. |
Q52188536 | Activation of the metaphase checkpoint and an apoptosis programme in the early zebrafish embryo, by treatment with the spindle-destabilising agent nocodazole |
Q40431966 | Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization. |
Q44527875 | Analysis of detached human kinetochores |
Q41711221 | Anaphase-Promoting Complex 7 is a Prognostic Factor in Human Colorectal Cancer |
Q34371170 | Aneuploidy and malignancy: an unsolved equation |
Q39022250 | Aneuploidy in Cancer and Aging |
Q28749887 | Anthropogenic pollutants: a threat to ecosystem sustainability? |
Q52370039 | Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells |
Q53407205 | Backbone resonances assignment of 19 kDa CD1 domain of human mitotic checkpoint serine/threonine-protein kinase, Bub1. |
Q27934394 | Bifurcation of the mitotic checkpoint pathway in budding yeast |
Q35750136 | Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis |
Q33786507 | Bub1p Kinase Activates the Saccharomyces cerevisiae Spindle Assembly Checkpoint |
Q24600680 | Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis |
Q24534626 | Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores |
Q36325139 | BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1. |
Q27933303 | Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2 |
Q24318410 | Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A |
Q38744041 | C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe. |
Q46518322 | CENP-E as an essential component of the mitotic checkpoint in vitro. |
Q38309596 | CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint |
Q36555958 | CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II. |
Q33946743 | CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells |
Q91812482 | CaMad2 Promotes Multiple Aspects of Genome Stability Beyond Its Direct Function in Chromosome Segregation |
Q40191642 | Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells |
Q38587989 | Causes of Chromosomal Instability |
Q30446001 | Cell Cycle Arrest in cdc20 Mutants of Saccharomyces cerevisiae Is Independent of Ndc10p and Kinetochore Function but Requires a Subset of Spindle Checkpoint Genes |
Q33608768 | Cell cycle control, checkpoint mechanisms, and genotoxic stress |
Q24314465 | Cell cycle, CDKs and cancer: a changing paradigm |
Q40781233 | Cell cycle-dependent interaction of Mad2 with conserved Box1/2 region of human granulocyte-macrophage colony-stimulating factor receptor common betac |
Q41642289 | Cell cycle: Checkpoint proteins and kinetochores |
Q47257517 | Cell-cycle Checkpoints and Aneuploidy on the Path to Cancer |
Q37457681 | Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro |
Q54689852 | Centrobin regulates the assembly of functional mitotic spindles |
Q33632358 | Centromere proteins and chromosome inheritance: a complex affair. |
Q29547850 | Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling |
Q41441718 | Centromeres, checkpoints and chromatid cohesion. |
Q80181472 | Centrosome amplification and aneuploidy in bone marrow failure patients |
Q34645278 | Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation |
Q22009979 | Characterization of MAD2B and other mitotic spindle checkpoint genes |
Q44013190 | Characterization of regions in hsMAD1 needed for binding hsMAD2. A polymorphic change in an hsMAD1 leucine zipper affects MAD1-MAD2 interaction and spindle checkpoint function |
Q42638933 | Characterization of the genes encoding for MAD2 homologues in wheat |
Q22003896 | Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1 |
Q39574377 | Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption |
Q24670095 | Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 |
Q24548359 | Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex |
Q52592906 | Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential |
Q22254761 | Chfr defines a mitotic stress checkpoint that delays entry into metaphase |
Q42258874 | Chromosomal instability and human cancer |
Q39787703 | Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic-spindle checkpoint. |
Q28588417 | Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 |
Q34119639 | Chromosome segregation and cancer: cutting through the mystery |
Q37574636 | Clinical impact of aneuploidy on gastric cancer patients. |
Q46056223 | Combination analysis of Bub1 and Mad2 expression in endometrial cancer: act as a prognostic factor in endometrial cancer |
Q37357807 | Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. |
Q33882831 | Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans |
Q30300041 | Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint |
Q24312091 | Conservation of the centromere/kinetochore protein ZW10 |
Q28508134 | Conserved C-terminal domains of mCenp-F (LEK1) regulate subcellular localization and mitotic checkpoint delay |
Q42167079 | Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation |
Q33785051 | Control of mitotic transitions by the anaphase-promoting complex |
Q30657692 | Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment |
Q30477159 | Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance |
Q36504196 | Copper aerosols inhibit phytoplankton growth in the Mediterranean Sea |
Q41678512 | Coupling cell division and cell death to microtubule dynamics |
Q37183449 | Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol |
Q24297170 | Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint |
Q24683942 | Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase |
Q37725314 | Cytokinesis and cancer |
Q24652311 | Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation |
Q27933329 | Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint |
Q39707870 | Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin |
Q32063207 | Different susceptibilities of postmitotic checkpoint-proficient and -deficient Balb / 3T3 cells to ICRF-193, a catalytic inhibitor of DNA topoisomerase II. |
Q30452670 | Differential requirements for DNA replication in the activation of mitotic checkpoints in Saccharomyces cerevisiae |
Q30660029 | Disruption of astral microtubule contact with the cell cortex activates a Bub1, Bub3, and Mad3-dependent checkpoint in fission yeast |
Q42365316 | Docking of CDK1 with antibiotic drugs revealed novel therapeutic value in breast ductal cancer in situ |
Q27930132 | Dominant Alleles of Saccharomyces cerevisiae CDC20 Reveal Its Role in Promoting Anaphase |
Q21195153 | Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships |
Q42421337 | Dual regulation of Mad2 localization on kinetochores by Bub1 and Dam1/DASH that ensure proper spindle interaction |
Q44714286 | Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability |
Q75281985 | Dynamic distribution of TTK in HeLa cells: insights from an ultrastructural study |
Q53547506 | Dynein participates in chromosome segregation in fission yeast |
Q36066030 | Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer. |
Q37419092 | Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells. |
Q30307758 | Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes. |
Q39520095 | Escherichia coli CdtB mediates cytolethal distending toxin cell cycle arrest |
Q73347715 | Evaluation of the role of mitotic instability in karyotypically normal men with oligozoospermia |
Q22010696 | Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta |
Q34354345 | Evolutionary conservation between budding yeast and human kinetochores |
Q35182909 | Expression and function analysis of mitotic checkpoint genes identifies TTK as a potential therapeutic target for human hepatocellular carcinoma |
Q40844047 | Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells |
Q50666071 | Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development |
Q41834181 | Expression of mitotic-arrest deficiency 2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer |
Q24305422 | FAT10 plays a role in the regulation of chromosomal stability |
Q51546149 | FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition |
Q36328520 | Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis |
Q27323083 | Fission yeast cells undergo nuclear division in the absence of spindle microtubules |
Q39645373 | Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint |
Q52545781 | Frequent impairment of the spindle assembly checkpoint in hepatocellular carcinoma |
Q34792908 | G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells |
Q33910498 | Generating chromosome instability through the simultaneous deletion of Mad2 and p53. |
Q28131826 | Genetic instabilities in human cancers |
Q38068039 | Genetic instability: tipping the balance |
Q33836026 | Genomic and epigenetic instability in colorectal cancer pathogenesis |
Q40704303 | Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers |
Q29347248 | Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E |
Q40619789 | HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression |
Q24683651 | HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture. |
Q39636406 | HsMAD2 mRNA expression may be a predictor of sensitivity to paclitaxel and survival in neuroblastoma |
Q22010522 | Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC |
Q24299555 | Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1 |
Q24682987 | Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores |
Q24336250 | Human T Cell Leukemia Virus Type 1 Oncoprotein Tax Targets the Human Mitotic Checkpoint Protein MAD1 |
Q24290711 | Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores |
Q24338369 | Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway |
Q54678246 | Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias |
Q24299241 | Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase |
Q92312659 | Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis |
Q24321983 | Identification of a MAD2-binding protein, CMT2, and its role in mitosis |
Q24550894 | Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation |
Q78103256 | Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes, hsMAD2 and p55CDC, in human lung cancers |
Q28595006 | Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein |
Q37872301 | Implications of genomic instability in the diagnosis and treatment of breast cancer |
Q43601540 | In vitro effects of albendazole and its metabolites on the cell proliferation kinetics and micronuclei frequency of stimulated human lymphocytes. |
Q34733119 | Inducing precocious anaphase in cultured mammalian cells |
Q40876361 | Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer |
Q39710967 | Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP. |
Q27649986 | Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer |
Q28307097 | Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation |
Q22010715 | Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1 |
Q33872372 | Interplay between CDC2 kinase and MAP kinase pathway during maturation of mammalian oocytes |
Q35668600 | Kif18a is specifically required for mitotic progression during germ line development. |
Q30305838 | Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells |
Q29618221 | Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage |
Q30448761 | Kinetochore localization of spindle checkpoint proteins: who controls whom? |
Q74535893 | Lack of tension at kinetochores activates the spindle checkpoint in budding yeast |
Q24548054 | Lesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiae |
Q38015243 | Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy |
Q29620330 | Localization of Mad2 to Kinetochores Depends on Microtubule Attachment, Not Tension |
Q47747732 | MAD2 as a key component of mitotic checkpoint: A probable prognostic factor for gastric cancer |
Q24648493 | MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity |
Q28593914 | MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells |
Q40677568 | MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells |
Q24291452 | MAD2B is an inhibitor of the anaphase-promoting complex |
Q40109309 | MAD2DeltaC induces aneuploidy and promotes anchorage-independent growth in human prostate epithelial cells |
Q37143221 | MAD2γ, a novel MAD2 isoform, reduces mitotic arrest and is associated with resistance in testicular germ cell tumors |
Q27935794 | MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p |
Q28475490 | MPF Governs the Assembly and Contraction of Actomyosin Rings by Activating RhoA and MAPK during Chemical-Induced Cytokinesis of Goat Oocytes |
Q34168724 | Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. |
Q36178158 | Mad2 and p27 expression profiles in colorectal cancer and its clinical significance |
Q36309195 | Mad2 and p53 expression profiles in colorectal cancer and its clinical significance |
Q40947072 | Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis. |
Q24534571 | Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint |
Q34708764 | Mad2 haploinsufficiency protects hematopoietic progenitor cells subjected to cell-cycle stress in vivo and to inhibition of redox function of Ape1/Ref-1 in vitro |
Q35642838 | Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells |
Q34582843 | Mad2 phosphorylation regulates its association with Mad1 and the APC/C. |
Q33763645 | Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes |
Q24682864 | Mad2 transiently associates with an APC/p55Cdc complex during mitosis |
Q34101240 | Mad2-Independent Inhibition of APCCdc20 by the Mitotic Checkpoint Protein BubR1 |
Q36879638 | Making an effective switch at the kinetochore by phosphorylation and dephosphorylation |
Q28568126 | Mammalian BUB1 Protein Kinases: Map Positions andin VivoExpression |
Q36452963 | Mammalian chromosomes containcis‐acting elements that control replication timing, mitotic condensation, and stability of entire chromosomes |
Q24635263 | Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints |
Q24683053 | Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events |
Q28272880 | Map Location and Gene Structure of theHomo sapiensMitotic Arrest Deficient 2 (MAD2L1) Gene at 4q27 |
Q34119143 | Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery |
Q37193068 | Mechanisms of chromosomal instability. |
Q30442107 | Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase |
Q24679267 | Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling |
Q34368625 | Microtubule-associated proteins and their essential roles during mitosis. |
Q24555706 | Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores |
Q41713562 | Microtubules and actin filaments: dynamic targets for cancer chemotherapy |
Q41744223 | Mitosis and checkpoints that control progression through mitosis in vertebrate somatic cells |
Q55171502 | Mitotic checkpoint protein hsMAD2 as a marker predicting liver metastasis of human gastric cancers |
Q35132582 | Mitotic checkpoints, genetic instability, and cancer |
Q34132846 | Mitotic checkpoints: from yeast to cancer |
Q33926467 | Mitotic chromosomal instability and cancer: mouse modelling of the human disease. |
Q37279001 | Molecular alterations associated with bladder cancer initiation and progression |
Q40799396 | Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer |
Q28202760 | Molecular cloning and characterization of the human budding uninhibited by benomyl (BUB3) promoter |
Q30441327 | Molecular credentialing of rodent bladder carcinogenesis models |
Q34154624 | Motility proteins and the origin of the nucleus |
Q33640520 | Mouse hematopoietic stem cells, unlike human and mouse embryonic stem cells, exhibit checkpoint-apoptosis coupling |
Q43680754 | Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. |
Q24306340 | Multiple roles of vertebrate REV genes in DNA repair and recombination |
Q40944054 | Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines |
Q30326722 | Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines. |
Q52536820 | Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers |
Q73135768 | Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines |
Q36382112 | Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila |
Q24320018 | Mutations of mitotic checkpoint genes in human cancers |
Q34386933 | Mutual antagonism between the anaphase promoting complex and the spindle assembly checkpoint contributes to mitotic timing in Caenorhabditis elegans |
Q90485059 | Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Cancer Surveillance in Fanconi Anemia |
Q24310671 | NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling |
Q37745480 | Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. |
Q26825698 | Non-targeted effects of ionising radiation--implications for low dose risk. |
Q46811004 | Numerical aberrations of chromosomes 1 and 7 by fluorescent in situ hybridization and DNA ploidy analysis in breast cancer |
Q29619455 | On the road to cancer: aneuploidy and the mitotic checkpoint |
Q34950012 | Orchestrating nuclear envelope disassembly and reassembly during mitosis |
Q83535210 | Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients |
Q34615320 | Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae |
Q33947088 | Paclitaxel-induced cell death: where the cell cycle and apoptosis come together |
Q46396099 | Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol |
Q92840478 | Pathological significance of MAD2L1 in breast cancer: an immunohistochemical study and meta analysis |
Q37491603 | Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint |
Q22009360 | Phosphorylation of human MAD1 by the BUB1 kinase in vitro |
Q34076444 | Phosphorylation of nucleoporin Tpr governs its differential localization and is required for its mitotic function |
Q36798836 | Polyplex exposure inhibits cell cycle, increases inflammatory response, and can cause protein expression without cell division. |
Q33829619 | Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system |
Q91529267 | Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved |
Q24685871 | Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. |
Q28214604 | Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis |
Q24315748 | Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint |
Q37709125 | Prognostic and predictive values of CDK1 and MAD2L1 in lung adenocarcinoma. |
Q33574972 | Prognostic utility of chromosomal instability detected by fluorescence in situ hybridization in fine-needle aspirates from oral squamous cell carcinomas |
Q36694133 | Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia |
Q24299702 | Re-evaluating the role of Tao1 in the spindle checkpoint |
Q34646656 | Recent advances in cancer research: mouse models of tumorigenesis |
Q30452748 | Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere |
Q38612159 | Regulation of the Cyclin B Degradation System by an Inhibitor of Mitotic Proteolysis |
Q37015055 | Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1). |
Q35552257 | Retention of the BUB3 checkpoint protein on lagging chromosomes |
Q34019827 | Role of Cyclin B1/Cdc2 Up-Regulation in the Development of Mitotic Prometaphase Arrest in Human Breast Cancer Cells Treated with Nocodazole |
Q40249347 | Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells |
Q39285369 | Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest |
Q74114602 | Role of mitotic control in spermatogenesis |
Q34182193 | Roles of MAPK and Spindle Assembly Checkpoint in Spontaneous Activation and MIII Arrest of Rat Oocytes |
Q36123872 | SAC-ing mitotic errors: how the spindle assembly checkpoint (SAC) plays defense against chromosome mis-segregation |
Q58126198 | Screening of cell cycle-related genes regulated by KIAA0101 in gastric cancer |
Q73270846 | Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers |
Q28190327 | Securin is required for chromosomal stability in human cells |
Q93163984 | Separase-triggered apoptosis enforces minimal length of mitosis |
Q24305356 | Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1 |
Q42673791 | Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage |
Q24676152 | Specific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2 |
Q33497326 | Spindle assembly checkpoint protein dynamics reveal conserved and unsuspected roles in plant cell division |
Q47281299 | Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents |
Q24679269 | Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity |
Q24682946 | Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores |
Q33787823 | Spindle checkpoint requires Mad1-bound and Mad1-free Mad2. |
Q42930766 | Spindle checkpoint signaling requires the mis6 kinetochore subcomplex, which interacts with mad2 and mitotic spindles |
Q39687466 | Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/Dis1-MAPs in fission yeast |
Q22008675 | Structural requirements and dynamics of mitosin-kinetochore interaction in M phase |
Q24534133 | Structure and interactions of the translation initiation factor eIF1 |
Q33581534 | Suppression of chemically induced and spontaneous mouse oocyte activation by AMP-activated protein kinase |
Q37544007 | Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors |
Q46288094 | Taming the Beast: Control of APC/C(Cdc20)-Dependent Destruction. |
Q41392338 | Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion. |
Q30498045 | Temporal changes in Hec1 phosphorylation control kinetochore–microtubule attachment stability during mitosis |
Q48460354 | Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells |
Q37595514 | The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli |
Q39732713 | The DNA damage response to non-replicating adeno-associated virus: Centriole overduplication and mitotic catastrophe independent of the spindle checkpoint. |
Q24298478 | The GTPase Gem and its partner Kif9 are required for chromosome alignment, spindle length control, and mitotic progression |
Q32010161 | The HORMA domain: a common structural denominator in mitotic checkpoints, chromosome synapsis and DNA repair |
Q64056668 | The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells |
Q24314385 | The Human Homologue of Bub3 Is Required for Kinetochore Localization of Bub1 and a Mad3/Bub1-related Protein Kinase |
Q61735093 | The Kinetochore of Higher Eucaryotes: A Molecular View |
Q27637433 | The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20 |
Q24290969 | The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation |
Q28586108 | The Sac3 homologue shd1 is involved in mitotic progression in mammalian cells |
Q24683919 | The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex |
Q24316058 | The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells |
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