A model for Batten disease protein CLN3: functional implications from homology and mutations

scientific article

A model for Batten disease protein CLN3: functional implications from homology and mutations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(96)01290-2
P698PubMed publication ID8980123
P5875ResearchGate publication ID14228110

P50authorSara E. MoleQ42563205
Bonnie Ann WallaceQ41770829
P2093author name stringR M Gardiner
P B Munroe
H M Mitchison
R W Janes
P2860cites workYeast genes and human diseaseQ48066231
Basic local alignment search toolQ25938991
A simple method for displaying the hydropathic character of a proteinQ26778481
Multiple sequence alignment with hierarchical clusteringQ27860956
The ENZYME data bankQ28239413
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The SWISS-PROT protein sequence data bank: current statusQ33463176
Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteinsQ34181973
PROSITE: recent developmentsQ34870115
Neuronal ceroid-lipofuscinoses in childhoodQ39649997
Waterlogged MoleculesQ40164690
Batten disease and mitochondrial pathways of proteolysisQ41115539
The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthaseQ41197592
Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferaseQ42091424
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)75-77
P577publication date1996-12-01
P1433published inFEBS LettersQ1388051
P1476titleA model for Batten disease protein CLN3: functional implications from homology and mutations
P478volume399

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cites work (P2860)
Q45094647A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting
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Q34238658Biochemistry of neuronal ceroid lipofuscinoses
Q24310339Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease
Q55043107C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes.
Q22254722CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells
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Q24802601Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
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Q24633059Mutations in a novel CLN6-encoded transmembrane protein cause variant neuronal ceroid lipofuscinosis in man and mouse
Q34238591Neuronal ceroid lipofuscinoses: classification and diagnosis
Q34238638Outlook for future treatment
Q33639100Paul Dyken Lecture of the Southern Pediatric Neurology Society. Inherited neurodegenerative disease: the evolution of our thinking
Q41010705Specific alterations in levels of mannose 6-phosphorylated glycoproteins in different neuronal ceroid lipofuscinoses
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Q22009145Studies of membrane association of CLN3 protein
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Q31148303The transmembrane topology of Batten disease protein CLN3 determined by consensus computational prediction constrained by experimental data
Q40648630Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells
Q39598497btn1 affects endocytosis, polarization of sterol-rich membrane domains and polarized growth in Schizosaccharomyces pombe

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